REACTOME_TRANSCRIPTIONAL_REGULATION_OF_TESTIS_DIFFERENTIATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SOX9 Transcription factor SOX-9 [1] 0.08[2] 0.15[3] 0.32[4] -0.21[5] -2.31[6] -2.60[7]
2 GATA4 Transcription factor GATA-4 [8] -1.49[9] -1.62[10] 0.13[11] -0.50[12] 1.09[13] 1.11[14]
3 NR5A1 Steroidogenic factor 1 [15] 1.49[16] 1.27[17] -4.22[18] -6.06[19] -7.49[20] -8.84[21]
4 PTGDS Prostaglandin-H2 D-isomerase [22] -1.79[23] -1.67[24] -10.22[25] 0.54[26] -0.70[27] 1.42[28]
5 WNT4 Protein Wnt-4 [29] -5.97[30] -5.17[31] -5.96[32] -0.64[33] -3.32[34] 0.74[35]
6 SRY Sex-determining region Y protein [36] -1.02[37] -1.12[38] [39] [40] [41] [42]
7 AMH Muellerian-inhibiting factor [43] -3.40[44] 1.06[45] 4.15[46] 2.61[47] 4.56[48] 2.04[49]
8 ZFPM2 Zinc finger protein ZFPM2 [50] [51] -1.36[52] -3.54[53] 6.62[54] 6.81[55] 7.50[56]
9 FGF9 Fibroblast growth factor 9 [57] -0.02[58] -3.74[59] [60] 3.51[61] -2.97[62] 0.63[63]
10 DMRT1 Doublesex- and mab-3-related transcription factor 1 [64] [65] [66] [67] [68] [69] [70]
11 FOXL2 Forkhead box protein L2 [71] [72] [73] [74] [75] [76] [77]
12 DHH Desert hedgehog protein [78] [79] [80] [81] [82] [83] [84]
13 WT1 Wilms tumor protein [85] [86] [87] [88] [89] [90] [91]
[1]
ref_hepatocyte SOX9
Mean 6.44
Standard deviation 14
Values 31 0.028 0.63 0.17 0.27
[2]
HepG2 SOX9
Mean 73.1
Standard deviation 8
Values 79 67
[3]
HepG2.C3A SOX9
Mean 71.7
Standard deviation 24
Values 89 55
[4]
HuH.7 SOX9
Mean 61.6
Standard deviation 13
Values 75 50 60
[5]
SNU475 SOX9
Mean 6.21
Standard deviation 0.59
Values 6.6 5.8
[6]
THLE SOX9
Mean 4.14
Standard deviation 0.56
Values 4.5 3.7
[7]
liver SOX9
Mean 1.05
Standard deviation 0.26
Values 0.78 0.96 1.1 1.4
[8]
ref_hepatocyte GATA4
Mean 3.97
Standard deviation 2.3
Values 6.3 1 2.3 6 4.3
[9]
HepG2 GATA4
Mean 15.1
Standard deviation 1.5
Values 14 16
[10]
HepG2.C3A GATA4
Mean 12.9
Standard deviation 0.72
Values 13 12
[11]
HuH.7 GATA4
Mean 33.3
Standard deviation 6.5
Values 30 41 29
[12]
SNU475 GATA4
Mean 3.13
Standard deviation 0.12
Values 3.2 3
[13]
THLE GATA4
Mean 26.9
Standard deviation 1.1
Values 26 28
[14]
liver GATA4
Mean 8.47
Standard deviation 2.5
Values 12 6.8 9.2 6.2
[15]
ref_hepatocyte NR5A1
Mean 1.54
Standard deviation 3.4
Values 7.7 0 0 0 0.024
[16]
HepG2 NR5A1
Mean 46.3
Standard deviation 3.3
Values 49 44
[17]
HepG2.C3A NR5A1
Mean 37.1
Standard deviation 14
Values 47 27
[18]
HuH.7 NR5A1
Mean 0.634
Standard deviation 0.33
Values 0.4 1 0.49
[19]
SNU475 NR5A1
Mean 0.0257
Standard deviation 0.029
Values 0.046 0.0051
[20]
THLE NR5A1
Mean 0.0275
Standard deviation 0.014
Values 0.018 0.037
[21]
liver NR5A1
Mean 0.00331
Standard deviation 0.0066
Values 0 0 0 0.013
[22]
ref_hepatocyte PTGDS
Mean 0.485
Standard deviation 0.7
Values 0 0 0 0.9 1.5
[23]
HepG2 PTGDS
Mean 1.51
Standard deviation 1.9
Values 2.8 0.19
[24]
HepG2.C3A PTGDS
Mean 1.52
Standard deviation 1
Values 2.3 0.78
[25]
HuH.7 PTGDS
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[26]
SNU475 PTGDS
Mean 0.785
Standard deviation 0.16
Values 0.67 0.9
[27]
THLE PTGDS
Mean 0.956
Standard deviation 0.028
Values 0.98 0.94
[28]
liver PTGDS
Mean 1.28
Standard deviation 1.1
Values 2.4 0.23 2.1 0.46
[29]
ref_hepatocyte WNT4
Mean 0.276
Standard deviation 0.47
Values 0 0 0.3 1.1 0
[30]
HepG2 WNT4
Mean 0.0472
Standard deviation 0.0061
Values 0.052 0.043
[31]
HepG2.C3A WNT4
Mean 0.0764
Standard deviation 0.0019
Values 0.078 0.075
[32]
HuH.7 WNT4
Mean 0.034
Standard deviation 0.022
Values 0.033 0.013 0.056
[33]
SNU475 WNT4
Mean 0.197
Standard deviation 0.1
Values 0.13 0.27
[34]
THLE WNT4
Mean 0.0881
Standard deviation 0.034
Values 0.11 0.064
[35]
liver WNT4
Mean 0.454
Standard deviation 0.67
Values 0.024 0.3 0.051 1.4
[36]
ref_hepatocyte SRY
Mean 0.0268
Standard deviation 0.06
Values 0.13 0 0 0 0
[37]
HepG2 SRY
Mean 0.142
Standard deviation 0.13
Values 0.052 0.23
[38]
HepG2.C3A SRY
Mean 0.124
Standard deviation 0.037
Values 0.097 0.15
[39]
HuH.7 SRY
Mean 0
Standard deviation 0
Values 0 0 0
[40]
SNU475 SRY
Mean 0
Standard deviation 0
Values 0 0
[41]
THLE SRY
Mean 0
Standard deviation 0
Values 0 0
[42]
liver SRY
Mean 0
Standard deviation 0
Values 0 0 0 0
[43]
ref_hepatocyte AMH
Mean 0.0163
Standard deviation 0.036
Values 0 0 0 0 0.081
[44]
HepG2 AMH
Mean 0.0165
Standard deviation 0.0071
Values 0.011 0.021
[45]
HepG2.C3A AMH
Mean 0.338
Standard deviation 0.099
Values 0.41 0.27
[46]
HuH.7 AMH
Mean 2.21
Standard deviation 0.66
Values 1.5 2.4 2.7
[47]
SNU475 AMH
Mean 0.11
Standard deviation 0.038
Values 0.083 0.14
[48]
THLE AMH
Mean 1.23
Standard deviation 0.41
Values 1.5 0.94
[49]
liver AMH
Mean 0.0658
Standard deviation 0.08
Values 0.024 0.029 0.026 0.19
[50]
ref_hepatocyte ZFPM2
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[51]
HepG2 ZFPM2
Mean 0
Standard deviation 0
Values 0 0
[52]
HepG2.C3A ZFPM2
Mean 0.0253
Standard deviation 0.0055
Values 0.029 0.021
[53]
HuH.7 ZFPM2
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[54]
SNU475 ZFPM2
Mean 0.713
Standard deviation 0.4
Values 0.43 1
[55]
THLE ZFPM2
Mean 2.33
Standard deviation 0.7
Values 1.8 2.8
[56]
liver ZFPM2
Mean 1.16
Standard deviation 0.42
Values 1.1 1.5 0.59 1.5
[57]
ref_hepatocyte FGF9
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[58]
HepG2 FGF9
Mean 0.0687
Standard deviation 9.1e-05
Values 0.069 0.069
[59]
HepG2.C3A FGF9
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[60]
HuH.7 FGF9
Mean 0
Standard deviation 0
Values 0 0 0
[61]
SNU475 FGF9
Mean 0.0822
Standard deviation 0.08
Values 0.14 0.025
[62]
THLE FGF9
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[63]
liver FGF9
Mean 0.00993
Standard deviation 0.02
Values 0 0 0 0.04
[64]
ref_hepatocyte DMRT1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 DMRT1
Mean 0.00501
Standard deviation 0.001
Values 0.0057 0.0043
[66]
HepG2.C3A DMRT1
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 DMRT1
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 DMRT1
Mean 0
Standard deviation 0
Values 0 0
[69]
THLE DMRT1
Mean 0.00828
Standard deviation 0.0033
Values 0.0059 0.011
[70]
liver DMRT1
Mean 0.00662
Standard deviation 0.013
Values 0 0 0 0.026
[71]
ref_hepatocyte FOXL2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[72]
HepG2 FOXL2
Mean 0.0558
Standard deviation 0.055
Values 0.017 0.094
[73]
HepG2.C3A FOXL2
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[74]
HuH.7 FOXL2
Mean 0.136
Standard deviation 0.033
Values 0.098 0.16 0.15
[75]
SNU475 FOXL2
Mean 2.71
Standard deviation 0.15
Values 2.6 2.8
[76]
THLE FOXL2
Mean 1.6
Standard deviation 0.29
Values 1.4 1.8
[77]
liver FOXL2
Mean 0
Standard deviation 0
Values 0 0 0 0
[78]
ref_hepatocyte DHH
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 DHH
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[80]
HepG2.C3A DHH
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[81]
HuH.7 DHH
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[82]
SNU475 DHH
Mean 0.00696
Standard deviation 0.0098
Values 0.014 0
[83]
THLE DHH
Mean 0.0225
Standard deviation 0.0017
Values 0.024 0.021
[84]
liver DHH
Mean 0.03
Standard deviation 0.051
Values 0 0.014 0 0.11
[85]
ref_hepatocyte WT1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 WT1
Mean 0.593
Standard deviation 0.28
Values 0.79 0.39
[87]
HepG2.C3A WT1
Mean 3.91
Standard deviation 0.87
Values 3.3 4.5
[88]
HuH.7 WT1
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[89]
SNU475 WT1
Mean 0.247
Standard deviation 0.23
Values 0.083 0.41
[90]
THLE WT1
Mean 3.5
Standard deviation 1
Values 2.8 4.2
[91]
liver WT1
Mean 0.0592
Standard deviation 0.062
Values 0.094 0.014 0.13 0