REACTOME_BIOSYNTHESIS_OF_EPA_DERIVED_SPMS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GPX4 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial [1] -0.14[2] -0.19[3] -0.81[4] -0.20[5] -0.87[6] -0.60[7]
2 HPGD 15-hydroxyprostaglandin dehydrogenase [NAD(+)] [8] -6.48[9] -7.18[10] 1.64[11] -4.34[12] -5.14[13] 1.81[14]
3 LTA4H Leukotriene A-4 hydrolase [15] 1.69[16] 1.87[17] 1.35[18] 1.84[19] 2.07[20] -0.33[21]
4 ALOX5 Arachidonate 5-lipoxygenase [22] 0.80[23] -5.00[24] -5.24[25] -4.67[26] -3.68[27] 4.01[28]
5 PTGS2 Prostaglandin G/H synthase 2 [29] [30] -1.40[31] -1.47[32] 5.32[33] 10.88[34] 4.03[35]
6 ALOX15 Arachidonate 15-lipoxygenase [36] 3.28[37] -1.24[38] 3.03[39] 0.70[40] 0.88[41] 0.25[42]
[1]
ref_hepatocyte GPX4
Mean 223
Standard deviation 63
Values 3.1e+02 1.4e+02 2.2e+02 2e+02 2.5e+02
[2]
HepG2 GPX4
Mean 141
Standard deviation 10
Values 1.5e+02 1.3e+02
[3]
HepG2.C3A GPX4
Mean 164
Standard deviation 3.3
Values 1.7e+02 1.6e+02
[4]
HuH.7 GPX4
Mean 128
Standard deviation 29
Values 1.1e+02 1.1e+02 1.6e+02
[5]
SNU475 GPX4
Mean 64.8
Standard deviation 11
Values 73 57
[6]
THLE GPX4
Mean 54.8
Standard deviation 1.7
Values 54 56
[7]
liver GPX4
Mean 91.2
Standard deviation 88
Values 1.7e+02 18 1.6e+02 12
[8]
ref_hepatocyte HPGD
Mean 29.5
Standard deviation 45
Values 0.17 5.7 1.8 35 1.1e+02
[9]
HepG2 HPGD
Mean 0.23
Standard deviation 0.13
Values 0.14 0.32
[10]
HepG2.C3A HPGD
Mean 0.172
Standard deviation 0.12
Values 0.087 0.26
[11]
HuH.7 HPGD
Mean 92.8
Standard deviation 79
Values 46 1.8e+02 48
[12]
SNU475 HPGD
Mean 0.487
Standard deviation 0.29
Values 0.7 0.28
[13]
THLE HPGD
Mean 0.376
Standard deviation 0.08
Values 0.43 0.32
[14]
liver HPGD
Mean 64.5
Standard deviation 48
Values 25 68 1.3e+02 35
[15]
ref_hepatocyte LTA4H
Mean 21.8
Standard deviation 17
Values 50 24 8.9 13 13
[16]
HepG2 LTA4H
Mean 48.8
Standard deviation 6.4
Values 53 44
[17]
HepG2.C3A LTA4H
Mean 67.1
Standard deviation 27
Values 86 48
[18]
HuH.7 LTA4H
Mean 55.9
Standard deviation 9.7
Values 48 67 53
[19]
SNU475 LTA4H
Mean 26
Standard deviation 1.8
Values 27 25
[20]
THLE LTA4H
Mean 40.9
Standard deviation 1.6
Values 40 42
[21]
liver LTA4H
Mean 10.7
Standard deviation 1.4
Values 11 11 13 9
[22]
ref_hepatocyte ALOX5
Mean 0.387
Standard deviation 0.51
Values 0 0.18 0 0.53 1.2
[23]
HepG2 ALOX5
Mean 0.467
Standard deviation 0.66
Values 0.93 0
[24]
HepG2.C3A ALOX5
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[25]
HuH.7 ALOX5
Mean 0.0103
Standard deviation 0.013
Values 0.025 0.0064 0
[26]
SNU475 ALOX5
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[27]
THLE ALOX5
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[28]
liver ALOX5
Mean 3.87
Standard deviation 1.4
Values 2.2 4.4 3.4 5.5
[29]
ref_hepatocyte PTGS2
Mean 0.032
Standard deviation 0.045
Values 0 0 0 0.095 0.065
[30]
HepG2 PTGS2
Mean 0
Standard deviation 0
Values 0 0
[31]
HepG2.C3A PTGS2
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[32]
HuH.7 PTGS2
Mean 0.0117
Standard deviation 0.013
Values 0 0.026 0.0094
[33]
SNU475 PTGS2
Mean 0.428
Standard deviation 0.51
Values 0.07 0.79
[34]
THLE PTGS2
Mean 27
Standard deviation 7.8
Values 33 22
[35]
liver PTGS2
Mean 0.325
Standard deviation 0.24
Values 0.24 0.67 0.13 0.26
[36]
ref_hepatocyte ALOX15
Mean 0.0272
Standard deviation 0.03
Values 0 0 0.019 0.052 0.065
[37]
HepG2 ALOX15
Mean 0.183
Standard deviation 0.19
Values 0.32 0.051
[38]
HepG2.C3A ALOX15
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[39]
HuH.7 ALOX15
Mean 0.223
Standard deviation 0.099
Values 0.27 0.11 0.29
[40]
SNU475 ALOX15
Mean 0.0148
Standard deviation 0.0078
Values 0.0093 0.02
[41]
THLE ALOX15
Mean 0.0225
Standard deviation 0.0017
Values 0.024 0.021
[42]
liver ALOX15
Mean 0.0201
Standard deviation 0.031
Values 0 0.014 0 0.066