REACTOME_TRAIL_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 TNFSF10 Tumor necrosis factor ligand superfamily member 10 [1] -4.92[2] -3.46[3] -0.88[4] -2.41[5] -5.42[6] -1.46[7]
2 CFLAR CASP8 and FADD-like apoptosis regulator [8] -0.84[9] -0.23[10] -0.72[11] -0.48[12] -0.08[13] 1.49[14]
3 TNFRSF10B Tumor necrosis factor receptor superfamily member 10B [15] 1.54[16] 1.27[17] 1.03[18] -0.27[19] 1.58[20] -0.04[21]
4 FADD FAS-associated death domain protein [22] -0.41[23] -1.26[24] -0.58[25] 1.99[26] 0.05[27] -1.84[28]
5 CASP8 Caspase-8 [29] -0.43[30] 0.00[31] -0.87[32] -0.02[33] -0.52[34] -1.49[35]
6 TNFRSF10A Tumor necrosis factor receptor superfamily member 10A [36] -1.89[37] -2.50[38] -2.52[39] -2.96[40] -2.97[41] -1.78[42]
7 TNFRSF10D Tumor necrosis factor receptor superfamily member 10D [43] 1.30[44] 1.20[45] 1.71[46] 0.48[47] -0.13[48] -0.05[49]
8 CASP10 Caspase-10 [50] 0.77[51] 1.92[52] 0.83[53] 0.49[54] 0.78[55] 1.00[56]
[1]
ref_hepatocyte TNFSF10
Mean 20
Standard deviation 23
Values 13 4.3 4.9 18 61
[2]
HepG2 TNFSF10
Mean 1.99
Standard deviation 0.0057
Values 2 2
[3]
HepG2.C3A TNFSF10
Mean 5.38
Standard deviation 0.9
Values 6 4.8
[4]
HuH.7 TNFSF10
Mean 31.9
Standard deviation 15
Values 21 49 26
[5]
SNU475 TNFSF10
Mean 6.62
Standard deviation 4.6
Values 9.9 3.4
[6]
THLE TNFSF10
Mean 0.781
Standard deviation 0.14
Values 0.88 0.68
[7]
liver TNFSF10
Mean 10.8
Standard deviation 3.9
Values 14 7 8 15
[8]
ref_hepatocyte CFLAR
Mean 16.4
Standard deviation 8.4
Values 9.6 29 22 11 11
[9]
HepG2 CFLAR
Mean 27.8
Standard deviation 7.9
Values 22 33
[10]
HepG2.C3A CFLAR
Mean 41.4
Standard deviation 1.1
Values 42 41
[11]
HuH.7 CFLAR
Mean 29.2
Standard deviation 4.7
Values 27 35 26
[12]
SNU475 CFLAR
Mean 20.7
Standard deviation 4
Values 24 18
[13]
THLE CFLAR
Mean 25.9
Standard deviation 3.2
Values 28 24
[14]
liver CFLAR
Mean 68.9
Standard deviation 22
Values 63 73 44 97
[15]
ref_hepatocyte TNFRSF10B
Mean 14.6
Standard deviation 7.1
Values 17 19 23 9.2 5.4
[16]
HepG2 TNFRSF10B
Mean 128
Standard deviation 33
Values 1.5e+02 1e+02
[17]
HepG2.C3A TNFRSF10B
Mean 105
Standard deviation 32
Values 1.3e+02 82
[18]
HuH.7 TNFRSF10B
Mean 87.5
Standard deviation 7.5
Values 81 95 86
[19]
SNU475 TNFRSF10B
Mean 21.3
Standard deviation 2.9
Values 19 23
[20]
THLE TNFRSF10B
Mean 73
Standard deviation 11
Values 81 66
[21]
liver TNFRSF10B
Mean 21.3
Standard deviation 4.6
Values 21 22 16 27
[22]
ref_hepatocyte FADD
Mean 9.28
Standard deviation 6.6
Values 3.8 12 20 6.3 5.1
[23]
HepG2 FADD
Mean 21.1
Standard deviation 4.6
Values 24 18
[24]
HepG2.C3A FADD
Mean 11.5
Standard deviation 1.6
Values 10 13
[25]
HuH.7 FADD
Mean 18.2
Standard deviation 3.2
Values 16 16 22
[26]
SNU475 FADD
Mean 65.1
Standard deviation 11
Values 73 58
[27]
THLE FADD
Mean 16
Standard deviation 3.5
Values 14 19
[28]
liver FADD
Mean 3.86
Standard deviation 1.3
Values 2.5 4.9 3 5.1
[29]
ref_hepatocyte CASP8
Mean 8.88
Standard deviation 6.8
Values 18 13 8.9 1.9 2.8
[30]
HepG2 CASP8
Mean 19.9
Standard deviation 3.1
Values 22 18
[31]
HepG2.C3A CASP8
Mean 26.3
Standard deviation 13
Values 17 35
[32]
HuH.7 CASP8
Mean 14.2
Standard deviation 3.6
Values 14 11 18
[33]
SNU475 CASP8
Mean 15.4
Standard deviation 0.7
Values 16 15
[34]
THLE CASP8
Mean 10.3
Standard deviation 0.97
Values 9.6 11
[35]
liver CASP8
Mean 4.72
Standard deviation 0.87
Values 3.4 5.2 5.3 5
[36]
ref_hepatocyte TNFRSF10A
Mean 8.1
Standard deviation 8.4
Values 4.2 21 12 2.1 0.98
[37]
HepG2 TNFRSF10A
Mean 6.59
Standard deviation 2.7
Values 8.5 4.7
[38]
HepG2.C3A TNFRSF10A
Mean 4.25
Standard deviation 0.05
Values 4.2 4.3
[39]
HuH.7 TNFRSF10A
Mean 4.14
Standard deviation 0.46
Values 4.4 4.5 3.6
[40]
SNU475 TNFRSF10A
Mean 1.83
Standard deviation 0.29
Values 1.6 2
[41]
THLE TNFRSF10A
Mean 1.72
Standard deviation 0.37
Values 2 1.5
[42]
liver TNFRSF10A
Mean 3.52
Standard deviation 1.4
Values 1.8 5.2 3.1 4
[43]
ref_hepatocyte TNFRSF10D
Mean 5.54
Standard deviation 3.3
Values 3.3 7 9.8 6.4 1.2
[44]
HepG2 TNFRSF10D
Mean 41.1
Standard deviation 18
Values 54 28
[45]
HepG2.C3A TNFRSF10D
Mean 37.7
Standard deviation 9.3
Values 44 31
[46]
HuH.7 TNFRSF10D
Mean 53.1
Standard deviation 7.5
Values 50 62 48
[47]
SNU475 TNFRSF10D
Mean 13.6
Standard deviation 2.7
Values 12 15
[48]
THLE TNFRSF10D
Mean 8.47
Standard deviation 1.1
Values 9.3 7.7
[49]
liver TNFRSF10D
Mean 7.96
Standard deviation 1.4
Values 7.5 7.3 7.1 10
[50]
ref_hepatocyte CASP10
Mean 1.74
Standard deviation 0.76
Values 3 1 1.8 1.3 1.6
[51]
HepG2 CASP10
Mean 8.95
Standard deviation 0.044
Values 9 8.9
[52]
HepG2.C3A CASP10
Mean 19.5
Standard deviation 6.6
Values 24 15
[53]
HuH.7 CASP10
Mean 9.07
Standard deviation 0.43
Values 9 9.5 8.7
[54]
SNU475 CASP10
Mean 4.29
Standard deviation 1.6
Values 5.5 3.1
[55]
THLE CASP10
Mean 5
Standard deviation 0.38
Values 5.3 4.7
[56]
liver CASP10
Mean 5.18
Standard deviation 1.9
Values 3.7 7.8 3.9 5.3