REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX_WITHIN_TLR4_COMPLEX Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.04[2] -0.29[3] -0.40[4] -0.25[5] -0.15[6] -0.13[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] 0.40[16] 0.46[17] -0.03[18] 0.60[19] 0.22[20] 0.32[21]
4 CD14 Monocyte differentiation antigen CD14 [22] -6.18[23] -6.30[24] -3.75[25] -2.28[26] -3.82[27] 1.24[28]
5 UBA52 Ubiquitin-60S ribosomal protein L40 [29] 2.84[30] 2.69[31] 3.48[32] 2.00[33] 2.45[34] 1.09[35]
6 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [36] 2.52[37] 2.64[38] 2.65[39] 4.23[40] 3.32[41] 1.99[42]
7 MAP3K7 Mitogen-activated protein kinase kinase kinase 7 [43] 2.06[44] 3.08[45] 2.69[46] 3.02[47] 2.84[48] 2.00[49]
8 IRAK2 Interleukin-1 receptor-associated kinase-like 2 [50] 2.08[51] 2.13[52] 1.66[53] 0.10[54] 1.28[55] 0.73[56]
9 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 [57] 2.21[58] 4.11[59] 3.95[60] 2.88[61] 3.72[62] 2.58[63]
10 TICAM1 TIR domain-containing adapter molecule 1 [64] 1.45[65] 0.29[66] 0.97[67] 1.30[68] 1.99[69] 1.25[70]
11 TAB1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [71] 2.80[72] 3.40[73] 3.22[74] 2.54[75] 2.51[76] 1.97[77]
12 LY96 Lymphocyte antigen 96 [78] -0.50[79] -0.93[80] -7.61[81] 1.16[82] -2.82[83] 0.39[84]
13 TRAF6 TNF receptor-associated factor 6 [85] 3.25[86] 3.09[87] 3.39[88] 4.19[89] 3.28[90] 4.66[91]
14 TLR4 Toll-like receptor 4 [92] 2.43[93] -2.77[94] -3.92[95] -2.57[96] 7.49[97] 6.21[98]
15 TICAM2 TIR domain-containing adapter molecule 2 [99] -5.72[100] [101] -5.45[102] 1.03[103] 1.01[104] -0.23[105]
16 SARM1 Sterile alpha and TIR motif-containing protein 1 [106] 0.58[107] 0.80[108] 2.24[109] 1.20[110] 6.14[111] 4.75[112]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte CD14
Mean 148
Standard deviation 1.9e+02
Values 0.7 1.6 16 3.4e+02 3.8e+02
[23]
HepG2 CD14
Mean 1.01
Standard deviation 0.084
Values 1.1 0.95
[24]
HepG2.C3A CD14
Mean 0.856
Standard deviation 0.32
Values 1.1 0.63
[25]
HuH.7 CD14
Mean 5.78
Standard deviation 1.1
Values 5.8 4.7 6.9
[26]
SNU475 CD14
Mean 9.74
Standard deviation 1.9
Values 8.4 11
[27]
THLE CD14
Mean 4.8
Standard deviation 0.97
Values 5.5 4.1
[28]
liver CD14
Mean 148
Standard deviation 88
Values 2.1e+02 68 2.4e+02 77
[29]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[30]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[31]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[32]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[33]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[34]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[35]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[36]
ref_hepatocyte TAB2
Mean 9.62
Standard deviation 3.5
Values 7.9 8.1 16 8.4 7.8
[37]
HepG2 TAB2
Mean 27.4
Standard deviation 8.1
Values 22 33
[38]
HepG2.C3A TAB2
Mean 27.3
Standard deviation 2.5
Values 29 26
[39]
HuH.7 TAB2
Mean 31.5
Standard deviation 8.5
Values 28 41 25
[40]
SNU475 TAB2
Mean 57.4
Standard deviation 2.2
Values 59 56
[41]
THLE TAB2
Mean 44.2
Standard deviation 0.52
Values 44 45
[42]
liver TAB2
Mean 16.2
Standard deviation 4.7
Values 21 15 10 19
[43]
ref_hepatocyte MAP3K7
Mean 8.64
Standard deviation 6.6
Values 18 13 4.6 4 3.6
[44]
HepG2 MAP3K7
Mean 17.8
Standard deviation 6.7
Values 13 23
[45]
HepG2.C3A MAP3K7
Mean 33.3
Standard deviation 3
Values 31 35
[46]
HuH.7 MAP3K7
Mean 29.2
Standard deviation 2.3
Values 31 27 30
[47]
SNU475 MAP3K7
Mean 22.3
Standard deviation 2.2
Values 24 21
[48]
THLE MAP3K7
Mean 28.3
Standard deviation 1.5
Values 29 27
[49]
liver MAP3K7
Mean 14.6
Standard deviation 1.8
Values 14 16 16 12
[50]
ref_hepatocyte IRAK2
Mean 8.12
Standard deviation 8.7
Values 2.6 12 22 2.3 1.9
[51]
HepG2 IRAK2
Mean 17
Standard deviation 8.7
Values 23 11
[52]
HepG2.C3A IRAK2
Mean 16.3
Standard deviation 5.4
Values 20 12
[53]
HuH.7 IRAK2
Mean 13.4
Standard deviation 4.3
Values 10 18 11
[54]
SNU475 IRAK2
Mean 2.77
Standard deviation 1.6
Values 1.6 3.9
[55]
THLE IRAK2
Mean 9.08
Standard deviation 2
Values 7.7 10
[56]
liver IRAK2
Mean 5.68
Standard deviation 1
Values 4.5 5.2 6.5 6.5
[57]
ref_hepatocyte TAB3
Mean 6.67
Standard deviation 6.1
Values 17 5.7 5.5 1.9 3.1
[58]
HepG2 TAB3
Mean 15.3
Standard deviation 7.1
Values 10 20
[59]
HepG2.C3A TAB3
Mean 52.5
Standard deviation 9.3
Values 59 46
[60]
HuH.7 TAB3
Mean 53.9
Standard deviation 32
Values 42 90 30
[61]
SNU475 TAB3
Mean 15.6
Standard deviation 5
Values 19 12
[62]
THLE TAB3
Mean 40.2
Standard deviation 2.3
Values 42 39
[63]
liver TAB3
Mean 16.8
Standard deviation 3.6
Values 21 18 15 13
[64]
ref_hepatocyte TICAM1
Mean 4.75
Standard deviation 6.4
Values 0 1.4 16 3.4 3
[65]
HepG2 TICAM1
Mean 6.41
Standard deviation 2.9
Values 8.5 4.3
[66]
HepG2.C3A TICAM1
Mean 2.66
Standard deviation 0.59
Values 3.1 2.2
[67]
HuH.7 TICAM1
Mean 4.87
Standard deviation 0.33
Values 5.2 4.5 4.9
[68]
SNU475 TICAM1
Mean 3.73
Standard deviation 0.28
Values 3.5 3.9
[69]
THLE TICAM1
Mean 8.64
Standard deviation 1.3
Values 7.7 9.5
[70]
liver TICAM1
Mean 4.77
Standard deviation 3.4
Values 7.9 1.4 7.4 2.3
[71]
ref_hepatocyte TAB1
Mean 3.61
Standard deviation 1.3
Values 2.3 2.1 5.1 4.4 4.1
[72]
HepG2 TAB1
Mean 12.5
Standard deviation 0.3
Values 13 12
[73]
HepG2.C3A TAB1
Mean 17.4
Standard deviation 1.8
Values 19 16
[74]
HuH.7 TAB1
Mean 17.6
Standard deviation 2.2
Values 19 15 19
[75]
SNU475 TAB1
Mean 6.68
Standard deviation 1.2
Values 7.5 5.8
[76]
THLE TAB1
Mean 9.45
Standard deviation 1.6
Values 8.3 11
[77]
liver TAB1
Mean 5.99
Standard deviation 1.7
Values 7.6 4.1 7.1 5.1
[78]
ref_hepatocyte LY96
Mean 2.98
Standard deviation 1.7
Values 3 4.2 0 4 3.7
[79]
HepG2 LY96
Mean 1.05
Standard deviation 0.03
Values 1 1.1
[80]
HepG2.C3A LY96
Mean 0.711
Standard deviation 0.08
Values 0.77 0.65
[81]
HuH.7 LY96
Mean 0.008
Standard deviation 0.0015
Values 0.0082 0.0064 0.0094
[82]
SNU475 LY96
Mean 2.13
Standard deviation 0.56
Values 2.5 1.7
[83]
THLE LY96
Mean 0.194
Standard deviation 0.13
Values 0.1 0.29
[84]
liver LY96
Mean 1.65
Standard deviation 1.4
Values 2.6 0.6 3 0.34
[85]
ref_hepatocyte TRAF6
Mean 0.965
Standard deviation 0.32
Values 0.82 1 1.5 0.7 0.8
[86]
HepG2 TRAF6
Mean 4.54
Standard deviation 0.72
Values 4 5
[87]
HepG2.C3A TRAF6
Mean 3.74
Standard deviation 0.086
Values 3.8 3.7
[88]
HuH.7 TRAF6
Mean 5.32
Standard deviation 1
Values 5 6.4 4.5
[89]
SNU475 TRAF6
Mean 5.61
Standard deviation 0.46
Values 5.9 5.3
[90]
THLE TRAF6
Mean 4.31
Standard deviation 0.54
Values 3.9 4.7
[91]
liver TRAF6
Mean 10.3
Standard deviation 0.99
Values 9.7 12 9.8 10
[92]
ref_hepatocyte TLR4
Mean 0.547
Standard deviation 0.41
Values 0 1.1 0.33 0.64 0.66
[93]
HepG2 TLR4
Mean 1.46
Standard deviation 0.9
Values 0.82 2.1
[94]
HepG2.C3A TLR4
Mean 0.0365
Standard deviation 0.024
Values 0.019 0.054
[95]
HuH.7 TLR4
Mean 0.0189
Standard deviation 0.019
Values 0 0.019 0.037
[96]
SNU475 TLR4
Mean 0.0293
Standard deviation 0.0087
Values 0.023 0.035
[97]
THLE TLR4
Mean 45
Standard deviation 10
Values 52 38
[98]
liver TLR4
Mean 17.2
Standard deviation 6.3
Values 13 19 11 25
[99]
ref_hepatocyte TICAM2
Mean 0.456
Standard deviation 0.51
Values 0 0.53 0 0.51 1.2
[100]
HepG2 TICAM2
Mean 0.00429
Standard deviation 0.0061
Values 0 0.0086
[101]
HepG2.C3A TICAM2
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 TICAM2
Mean 0.00547
Standard deviation 0.0095
Values 0.016 0 0
[103]
SNU475 TICAM2
Mean 0.297
Standard deviation 0.053
Values 0.26 0.33
[104]
THLE TICAM2
Mean 0.422
Standard deviation 0.036
Values 0.4 0.45
[105]
liver TICAM2
Mean 0.164
Standard deviation 0.11
Values 0.21 0.14 0.026 0.28
[106]
ref_hepatocyte SARM1
Mean 0.16
Standard deviation 0.097
Values 0.066 0.067 0.16 0.29 0.21
[107]
HepG2 SARM1
Mean 0.118
Standard deviation 0.021
Values 0.1 0.13
[108]
HepG2.C3A SARM1
Mean 0.127
Standard deviation 0.013
Values 0.14 0.12
[109]
HuH.7 SARM1
Mean 0.395
Standard deviation 0.092
Values 0.3 0.49 0.39
[110]
SNU475 SARM1
Mean 0.117
Standard deviation 0.028
Values 0.097 0.14
[111]
THLE SARM1
Mean 5.16
Standard deviation 0.78
Values 4.6 5.7
[112]
liver SARM1
Mean 1.82
Standard deviation 0.21
Values 1.6 2 1.7 1.9