REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_DEATH_RECEPTORS_AND_LIGANDS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 TMEM219 Insulin-like growth factor-binding protein 3 receptor [1] -1.80[2] -1.18[3] -1.80[4] -1.79[5] -2.20[6] -1.97[7]
2 TNFRSF10B Tumor necrosis factor receptor superfamily member 10B [8] 1.22[9] 1.43[10] 1.17[11] 0.12[12] 1.54[13] -0.40[14]
3 FAS Tumor necrosis factor receptor superfamily member 6 [15] -2.37[16] -1.26[17] -9.32[18] -1.29[19] -0.96[20] -2.16[21]
4 TNFRSF10A Tumor necrosis factor receptor superfamily member 10A [22] -2.21[23] -2.34[24] -2.38[25] -2.57[26] -3.01[27] -2.14[28]
5 TP53BP2 Apoptosis-stimulating of p53 protein 2 [29] -1.37[30] -0.71[31] 0.81[32] 1.71[33] 0.81[34] -0.38[35]
6 TNFRSF10D Tumor necrosis factor receptor superfamily member 10D [36] 0.98[37] 1.35[38] 1.86[39] 0.87[40] -0.17[41] -0.42[42]
7 TP53 Cellular tumor antigen p53 [43] 0.87[44] 0.76[45] 1.47[46] 1.75[47] 1.22[48] -0.48[49]
8 IGFBP3 Insulin-like growth factor-binding protein 3 [50] 2.28[51] -2.28[52] -2.87[53] 0.90[54] -0.27[55] 3.79[56]
9 PPP1R13B Apoptosis-stimulating of p53 protein 1 [57] 0.77[58] 0.41[59] -0.57[60] 1.40[61] 1.06[62] 0.55[63]
10 TNFRSF10C Tumor necrosis factor receptor superfamily member 10C [64] -2.79[65] -1.55[66] -3.19[67] -2.86[68] -3.69[69] -0.03[70]
11 TP73 Tumor protein p73 [71] -0.04[72] 2.84[73] 1.71[74] 1.13[75] 2.07[76] 0.22[77]
12 TP63 Tumor protein 63 [78] [79] [80] -2.56[81] -0.92[82] -4.69[83] -1.91[84]
[1]
ref_hepatocyte TMEM219
Mean 35.9
Standard deviation 22
Values 18 19 28 42 72
[2]
HepG2 TMEM219
Mean 38.7
Standard deviation 1.3
Values 40 38
[3]
HepG2.C3A TMEM219
Mean 42.1
Standard deviation 9.6
Values 49 35
[4]
HuH.7 TMEM219
Mean 27.3
Standard deviation 3.4
Values 24 27 31
[5]
SNU475 TMEM219
Mean 13.9
Standard deviation 3.9
Values 17 11
[6]
THLE TMEM219
Mean 13.4
Standard deviation 2
Values 12 15
[7]
liver TMEM219
Mean 17.5
Standard deviation 16
Values 31 4.5 31 3
[8]
ref_hepatocyte TNFRSF10B
Mean 14.6
Standard deviation 7.1
Values 17 19 23 9.2 5.4
[9]
HepG2 TNFRSF10B
Mean 128
Standard deviation 33
Values 1.5e+02 1e+02
[10]
HepG2.C3A TNFRSF10B
Mean 105
Standard deviation 32
Values 1.3e+02 82
[11]
HuH.7 TNFRSF10B
Mean 87.5
Standard deviation 7.5
Values 81 95 86
[12]
SNU475 TNFRSF10B
Mean 21.3
Standard deviation 2.9
Values 19 23
[13]
THLE TNFRSF10B
Mean 73
Standard deviation 11
Values 81 66
[14]
liver TNFRSF10B
Mean 21.3
Standard deviation 4.6
Values 21 22 16 27
[15]
ref_hepatocyte FAS
Mean 10.9
Standard deviation 10
Values 5.6 28 13 5 3.1
[16]
HepG2 FAS
Mean 7.93
Standard deviation 5
Values 4.4 11
[17]
HepG2.C3A FAS
Mean 12.1
Standard deviation 8.5
Values 6.1 18
[18]
HuH.7 FAS
Mean 0.0451
Standard deviation 0.028
Values 0.041 0.019 0.075
[19]
SNU475 FAS
Mean 5.96
Standard deviation 1.8
Values 4.7 7.2
[20]
THLE FAS
Mean 9.58
Standard deviation 1.5
Values 11 8.5
[21]
liver FAS
Mean 4.68
Standard deviation 1.2
Values 6.4 4.1 4.5 3.7
[22]
ref_hepatocyte TNFRSF10A
Mean 8.1
Standard deviation 8.4
Values 4.2 21 12 2.1 0.98
[23]
HepG2 TNFRSF10A
Mean 6.59
Standard deviation 2.7
Values 8.5 4.7
[24]
HepG2.C3A TNFRSF10A
Mean 4.25
Standard deviation 0.05
Values 4.2 4.3
[25]
HuH.7 TNFRSF10A
Mean 4.14
Standard deviation 0.46
Values 4.4 4.5 3.6
[26]
SNU475 TNFRSF10A
Mean 1.83
Standard deviation 0.29
Values 1.6 2
[27]
THLE TNFRSF10A
Mean 1.72
Standard deviation 0.37
Values 2 1.5
[28]
liver TNFRSF10A
Mean 3.52
Standard deviation 1.4
Values 1.8 5.2 3.1 4
[29]
ref_hepatocyte TP53BP2
Mean 6.24
Standard deviation 6.5
Values 2.6 7.1 17 2.4 2
[30]
HepG2 TP53BP2
Mean 9.07
Standard deviation 1.2
Values 8.2 9.9
[31]
HepG2.C3A TP53BP2
Mean 10.2
Standard deviation 0.052
Values 10 10
[32]
HuH.7 TP53BP2
Mean 29.1
Standard deviation 12
Values 24 43 20
[33]
SNU475 TP53BP2
Mean 27.4
Standard deviation 1.5
Values 26 28
[34]
THLE TP53BP2
Mean 18.7
Standard deviation 0.31
Values 19 19
[35]
liver TP53BP2
Mean 9.23
Standard deviation 1.2
Values 8.3 11 8.1 9.9
[36]
ref_hepatocyte TNFRSF10D
Mean 5.54
Standard deviation 3.3
Values 3.3 7 9.8 6.4 1.2
[37]
HepG2 TNFRSF10D
Mean 41.1
Standard deviation 18
Values 54 28
[38]
HepG2.C3A TNFRSF10D
Mean 37.7
Standard deviation 9.3
Values 44 31
[39]
HuH.7 TNFRSF10D
Mean 53.1
Standard deviation 7.5
Values 50 62 48
[40]
SNU475 TNFRSF10D
Mean 13.6
Standard deviation 2.7
Values 12 15
[41]
THLE TNFRSF10D
Mean 8.47
Standard deviation 1.1
Values 9.3 7.7
[42]
liver TNFRSF10D
Mean 7.96
Standard deviation 1.4
Values 7.5 7.3 7.1 10
[43]
ref_hepatocyte TP53
Mean 5.28
Standard deviation 0.94
Values 5.5 3.7 6.2 5.5 5.5
[44]
HepG2 TP53
Mean 36.3
Standard deviation 0.12
Values 36 36
[45]
HepG2.C3A TP53
Mean 23.9
Standard deviation 1.8
Values 23 25
[46]
HuH.7 TP53
Mean 38.7
Standard deviation 16
Values 50 20 46
[47]
SNU475 TP53
Mean 23.7
Standard deviation 6.7
Values 28 19
[48]
THLE TP53
Mean 21.1
Standard deviation 6.6
Values 16 26
[49]
liver TP53
Mean 7.29
Standard deviation 2.3
Values 9 5 9.5 5.6
[50]
ref_hepatocyte IGFBP3
Mean 3.76
Standard deviation 3.4
Values 0 4.6 9.1 2.9 2.3
[51]
HepG2 IGFBP3
Mean 68.6
Standard deviation 93
Values 1.3e+02 2.6
[52]
HepG2.C3A IGFBP3
Mean 2.06
Standard deviation 1.8
Values 3.3 0.82
[53]
HuH.7 IGFBP3
Mean 1.37
Standard deviation 1.5
Values 0.47 3.1 0.58
[54]
SNU475 IGFBP3
Mean 9.43
Standard deviation 3.7
Values 12 6.8
[55]
THLE IGFBP3
Mean 5.34
Standard deviation 0.41
Values 5.1 5.6
[56]
liver IGFBP3
Mean 100
Standard deviation 51
Values 1.3e+02 83 1.5e+02 36
[57]
ref_hepatocyte PPP1R13B
Mean 1.88
Standard deviation 0.66
Values 2.2 2 2.8 1.3 1.2
[58]
HepG2 PPP1R13B
Mean 12.1
Standard deviation 1.7
Values 11 13
[59]
HepG2.C3A PPP1R13B
Mean 6.62
Standard deviation 0.98
Values 7.3 5.9
[60]
HuH.7 PPP1R13B
Mean 3.36
Standard deviation 0.41
Values 3.6 2.9 3.6
[61]
SNU475 PPP1R13B
Mean 6.65
Standard deviation 1.5
Values 7.7 5.6
[62]
THLE PPP1R13B
Mean 6.74
Standard deviation 0.32
Values 6.5 7
[63]
liver PPP1R13B
Mean 5.29
Standard deviation 1.2
Values 6.1 5.5 3.5 6.1
[64]
ref_hepatocyte TNFRSF10C
Mean 0.479
Standard deviation 0.47
Values 1.1 0.87 0.21 0.095 0.11
[65]
HepG2 TNFRSF10C
Mean 0.26
Standard deviation 0.07
Values 0.31 0.21
[66]
HepG2.C3A TNFRSF10C
Mean 0.435
Standard deviation 0.11
Values 0.52 0.35
[67]
HuH.7 TNFRSF10C
Mean 0.139
Standard deviation 0.0082
Values 0.14 0.15 0.13
[68]
SNU475 TNFRSF10C
Mean 0.0882
Standard deviation 0.046
Values 0.12 0.056
[69]
THLE TNFRSF10C
Mean 0.0636
Standard deviation 0.052
Values 0.1 0.027
[70]
liver TNFRSF10C
Mean 0.9
Standard deviation 0.36
Values 0.66 0.73 0.77 1.4
[71]
ref_hepatocyte TP73
Mean 0.183
Standard deviation 0.15
Values 0.4 0 0.19 0.23 0.098
[72]
HepG2 TP73
Mean 0.666
Standard deviation 0.13
Values 0.57 0.76
[73]
HepG2.C3A TP73
Mean 3.48
Standard deviation 0.49
Values 3.1 3.8
[74]
HuH.7 TP73
Mean 1.58
Standard deviation 0.41
Values 2.1 1.4 1.3
[75]
SNU475 TP73
Mean 0.537
Standard deviation 0.035
Values 0.56 0.51
[76]
THLE TP73
Mean 1.32
Standard deviation 0.075
Values 1.3 1.4
[77]
liver TP73
Mean 0.407
Standard deviation 0.19
Values 0.19 0.47 0.33 0.64
[78]
ref_hepatocyte TP63
Mean 0.0845
Standard deviation 0.17
Values 0 0.026 0.4 0 0
[79]
HepG2 TP63
Mean 0
Standard deviation 0
Values 0 0
[80]
HepG2.C3A TP63
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 TP63
Mean 0.038
Standard deviation 0.033
Values 0 0.058 0.056
[82]
SNU475 TP63
Mean 0.06
Standard deviation 0.059
Values 0.019 0.1
[83]
THLE TP63
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[84]
liver TP63
Mean 0.0431
Standard deviation 0.045
Values 0.024 0.043 0 0.11