REACTOME_TNF_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.65[2] -1.03[3] -0.89[4] -1.16[5] -0.80[6] -0.51[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] -0.21[16] -0.28[17] -0.53[18] -0.30[19] -0.43[20] -0.06[21]
4 UBA52 Ubiquitin-60S ribosomal protein L40 [22] 2.23[23] 1.95[24] 2.98[25] 1.09[26] 1.80[27] 0.71[28]
5 TNFRSF1A Tumor necrosis factor receptor superfamily member 1A [29] 1.08[30] 0.43[31] 0.72[32] 1.99[33] 2.06[34] 1.45[35]
6 SPPL2A Signal peptide peptidase-like 2A [36] -0.25[37] -0.03[38] -0.26[39] 1.58[40] 0.42[41] 1.64[42]
7 IKBKG NF-kappa-B essential modulator [43] 0.66[44] 0.62[45] -1.64[46] 0.77[47] -0.55[48] 0.77[49]
8 TAX1BP1 Tax1-binding protein 1 [50] 1.45[51] 2.44[52] 2.62[53] 2.60[54] 1.70[55] 1.92[56]
9 RBCK1 RanBP-type and C3HC4-type zinc finger-containing protein 1 [57] 2.46[58] 2.94[59] 1.06[60] 1.40[61] 0.67[62] 0.90[63]
10 CFLAR CASP8 and FADD-like apoptosis regulator [64] 1.16[65] 1.73[66] 1.27[67] 1.08[68] 1.13[69] 2.93[70]
11 BIRC3 Baculoviral IAP repeat-containing protein 3 [71] -1.57[72] -0.73[73] -3.13[74] -1.50[75] 2.16[76] -0.71[77]
12 TNFAIP3 Tumor necrosis factor alpha-induced protein 3 [78] 2.18[79] 2.70[80] -0.58[81] 0.41[82] 2.27[83] 0.34[84]
13 BIRC2 Baculoviral IAP repeat-containing protein 2 [85] 1.79[86] 2.56[87] 1.50[88] 2.04[89] 2.72[90] 2.10[91]
14 SHARPIN Sharpin [92] 1.28[93] 0.94[94] 0.96[95] 1.71[96] 1.08[97] 1.08[98]
15 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [99] 1.91[100] 1.90[101] 2.15[102] 3.32[103] 2.67[104] 1.61[105]
16 FADD FAS-associated death domain protein [106] 1.59[107] 0.70[108] 1.41[109] 3.55[110] 1.26[111] -0.40[112]
17 CASP8 Caspase-8 [113] 1.57[114] 1.96[115] 1.12[116] 1.54[117] 0.69[118] -0.05[119]
18 MAP3K7 Mitogen-activated protein kinase kinase kinase 7 [120] 1.45[121] 2.34[122] 2.19[123] 2.11[124] 2.19[125] 1.62[126]
19 TRAF1 TNF receptor-associated factor 1 [127] -2.88[128] -3.18[129] -2.35[130] -1.92[131] -1.46[132] -1.53[133]
20 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 [134] 1.60[135] 3.37[136] 3.45[137] 1.97[138] 3.07[139] 2.20[140]
21 TRADD Tumor necrosis factor receptor type 1-associated DEATH domain protein 1.29[141] 0.94[142] -0.24[143] 0.64[144] 0.38[145] 0.78[146]
22 USP4 Ubiquitin carboxyl-terminal hydrolase 4 [147] 1.73[148] 2.03[149] 1.27[150] 1.63[151] 2.51[152] 2.19[153]
23 TRAF2 TNF receptor-associated factor 2 [154] 1.78[155] 1.66[156] 1.38[157] 1.74[158] 1.65[159] 0.57[160]
24 ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 [161] 2.22[162] 1.92[163] 1.65[164] 3.36[165] 2.39[166] 1.45[167]
25 RIPK1 Receptor-interacting serine/threonine-protein kinase 1 [168] 1.84[169] 1.82[170] 1.49[171] 2.70[172] 2.12[173] 2.85[174]
26 CYLD Ubiquitin carboxyl-terminal hydrolase CYLD [175] 1.44[176] 1.40[177] 0.20[178] 2.57[179] 3.69[180] 3.31[181]
27 RNF31 E3 ubiquitin-protein ligase RNF31 [182] 3.99[183] 2.02[184] 2.80[185] 2.74[186] 2.22[187] 2.45[188]
28 CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha [189] 2.45[190] 3.49[191] 3.44[192] 2.27[193] 2.98[194] 2.88[195]
29 TAB1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [196] 2.19[197] 2.66[198] 2.73[199] 1.63[200] 1.86[201] 1.59[202]
30 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta [203] 2.07[204] 1.95[205] 2.04[206] 1.88[207] 1.87[208] 2.55[209]
31 BAG4 BAG family molecular chaperone regulator 4 [210] 1.90[211] 2.67[212] 3.96[213] 1.56[214] 1.68[215] 3.19[216]
32 NSMAF Protein FAN [217] 2.37[218] 2.09[219] -0.36[220] 3.67[221] 2.80[222] 1.54[223]
33 OTUD7B OTU domain-containing protein 7B [224] 2.62[225] 2.01[226] 2.41[227] 3.70[228] 3.05[229] 2.79[230]
34 SMPD2 Sphingomyelin phosphodiesterase 2 [231] 0.60[232] 0.75[233] 0.13[234] -0.15[235] 0.86[236] -0.24[237]
35 XIAP E3 ubiquitin-protein ligase XIAP [238] 3.06[239] 3.47[240] 3.92[241] 4.21[242] 3.53[243] 4.05[244]
36 SPPL2B Signal peptide peptidase-like 2B [245] 2.83[246] 2.90[247] 3.32[248] 2.10[249] 2.72[250] 2.60[251]
37 USP21 Ubiquitin carboxyl-terminal hydrolase 21 [252] 2.61[253] 2.58[254] 2.48[255] 3.13[256] 2.74[257] 1.41[258]
38 MADD MAP kinase-activating death domain protein [259] 4.10[260] 3.79[261] 4.19[262] 3.71[263] 3.30[264] 3.93[265]
39 USP2 Ubiquitin carboxyl-terminal hydrolase 2 [266] 2.76[267] 2.25[268] 1.26[269] 1.33[270] -0.27[271] 1.50[272]
40 SMPD3 Sphingomyelin phosphodiesterase 3 [273] 1.66[274] 1.96[275] 1.21[276] 1.95[277] 0.91[278] 4.29[279]
41 CLIP3 CAP-Gly domain-containing linker protein 3 [280] 1.74[281] 2.75[282] 2.81[283] 2.68[284] 6.93[285] 2.49[286]
42 TNF Tumor necrosis factor [287] 2.65[288] 0.33[289] -4.28[290] -0.60[291] -3.93[292] -0.52[293]
43 RACK1 Receptor of activated protein C kinase 1 [294] [295] [296] [297] [298] [299] [300]
44 OTULIN Ubiquitin thioesterase otulin [301] [302] [303] [304] [305] [306] [307]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[23]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[24]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[25]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[26]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[27]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[28]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[29]
ref_hepatocyte TNFRSF1A
Mean 30.7
Standard deviation 20
Values 11 15 24 55 48
[30]
HepG2 TNFRSF1A
Mean 49
Standard deviation 6
Values 53 45
[31]
HepG2.C3A TNFRSF1A
Mean 31.7
Standard deviation 8.2
Values 37 26
[32]
HuH.7 TNFRSF1A
Mean 37.3
Standard deviation 0.38
Values 38 37 37
[33]
SNU475 TNFRSF1A
Mean 72.7
Standard deviation 0.99
Values 73 72
[34]
THLE TNFRSF1A
Mean 92.5
Standard deviation 20
Values 78 1.1e+02
[35]
liver TNFRSF1A
Mean 46.1
Standard deviation 22
Values 51 26 74 33
[36]
ref_hepatocyte SPPL2A
Mean 23.6
Standard deviation 13
Values 22 45 11 21 20
[37]
HepG2 SPPL2A
Mean 15
Standard deviation 6
Values 11 19
[38]
HepG2.C3A SPPL2A
Mean 17.7
Standard deviation 2.9
Values 16 20
[39]
HuH.7 SPPL2A
Mean 14.6
Standard deviation 6
Values 11 22 11
[40]
SNU475 SPPL2A
Mean 42.2
Standard deviation 9.9
Values 49 35
[41]
THLE SPPL2A
Mean 22.7
Standard deviation 4.6
Values 19 26
[42]
liver SPPL2A
Mean 40.4
Standard deviation 11
Values 50 35 49 28
[43]
ref_hepatocyte IKBKG
Mean 22.7
Standard deviation 14
Values 7.4 36 37 24 10
[44]
HepG2 IKBKG
Mean 27.1
Standard deviation 5.7
Values 31 23
[45]
HepG2.C3A IKBKG
Mean 26.7
Standard deviation 4
Values 30 24
[46]
HuH.7 IKBKG
Mean 5.4
Standard deviation 1.3
Values 5.4 4.1 6.7
[47]
SNU475 IKBKG
Mean 23.2
Standard deviation 3.5
Values 21 26
[48]
THLE IKBKG
Mean 11.2
Standard deviation 1
Values 10 12
[49]
liver IKBKG
Mean 21.3
Standard deviation 6.6
Values 20 22 29 13
[50]
ref_hepatocyte TAX1BP1
Mean 21.1
Standard deviation 6.3
Values 24 31 17 18 16
[51]
HepG2 TAX1BP1
Mean 43.4
Standard deviation 7.8
Values 38 49
[52]
HepG2.C3A TAX1BP1
Mean 87.2
Standard deviation 12
Values 79 96
[53]
HuH.7 TAX1BP1
Mean 95.5
Standard deviation 13
Values 91 1.1e+02 85
[54]
SNU475 TAX1BP1
Mean 76.1
Standard deviation 2.5
Values 74 78
[55]
THLE TAX1BP1
Mean 49.2
Standard deviation 6.5
Values 54 45
[56]
liver TAX1BP1
Mean 43.9
Standard deviation 14
Values 54 41 55 26
[57]
ref_hepatocyte RBCK1
Mean 19
Standard deviation 9.1
Values 22 15 33 15 10
[58]
HepG2 RBCK1
Mean 79.2
Standard deviation 18
Values 92 67
[59]
HepG2.C3A RBCK1
Mean 111
Standard deviation 64
Values 1.6e+02 66
[60]
HuH.7 RBCK1
Mean 29.2
Standard deviation 2.1
Values 27 31 29
[61]
SNU475 RBCK1
Mean 29.9
Standard deviation 9.3
Values 36 23
[62]
THLE RBCK1
Mean 21.9
Standard deviation 2
Values 23 20
[63]
liver RBCK1
Mean 19.6
Standard deviation 6.5
Values 28 14 22 15
[64]
ref_hepatocyte CFLAR
Mean 16.4
Standard deviation 8.4
Values 9.6 29 22 11 11
[65]
HepG2 CFLAR
Mean 27.8
Standard deviation 7.9
Values 22 33
[66]
HepG2.C3A CFLAR
Mean 41.4
Standard deviation 1.1
Values 42 41
[67]
HuH.7 CFLAR
Mean 29.2
Standard deviation 4.7
Values 27 35 26
[68]
SNU475 CFLAR
Mean 20.7
Standard deviation 4
Values 24 18
[69]
THLE CFLAR
Mean 25.9
Standard deviation 3.2
Values 28 24
[70]
liver CFLAR
Mean 68.9
Standard deviation 22
Values 63 73 44 97
[71]
ref_hepatocyte BIRC3
Mean 15.6
Standard deviation 19
Values 1.2 29 43 1.5 3.2
[72]
HepG2 BIRC3
Mean 3.98
Standard deviation 0.49
Values 4.3 3.6
[73]
HepG2.C3A BIRC3
Mean 7.2
Standard deviation 0.46
Values 6.9 7.5
[74]
HuH.7 BIRC3
Mean 1.31
Standard deviation 1.3
Values 0.65 2.8 0.49
[75]
SNU475 BIRC3
Mean 3.3
Standard deviation 0.79
Values 2.7 3.9
[76]
THLE BIRC3
Mean 50.3
Standard deviation 18
Values 63 37
[77]
liver BIRC3
Mean 5.25
Standard deviation 1.9
Values 5.1 5 3.2 7.7
[78]
ref_hepatocyte TNFAIP3
Mean 11.3
Standard deviation 19
Values 4.3 2.5 44 3.7 1.5
[79]
HepG2 TNFAIP3
Mean 38.7
Standard deviation 5.9
Values 43 34
[80]
HepG2.C3A TNFAIP3
Mean 55.9
Standard deviation 5.4
Values 60 52
[81]
HuH.7 TNFAIP3
Mean 5.6
Standard deviation 2.8
Values 4.2 8.9 3.7
[82]
SNU475 TNFAIP3
Mean 8.95
Standard deviation 6.4
Values 4.4 13
[83]
THLE TNFAIP3
Mean 39.3
Standard deviation 6.8
Values 34 44
[84]
liver TNFAIP3
Mean 7.87
Standard deviation 2
Values 11 5.9 7.6 7.5
[85]
ref_hepatocyte BIRC2
Mean 10
Standard deviation 3.6
Values 13 14 11 6.4 5.8
[86]
HepG2 BIRC2
Mean 26.2
Standard deviation 3.4
Values 24 29
[87]
HepG2.C3A BIRC2
Mean 45.2
Standard deviation 3.6
Values 43 48
[88]
HuH.7 BIRC2
Mean 21
Standard deviation 4
Values 18 25 20
[89]
SNU475 BIRC2
Mean 24.6
Standard deviation 0.14
Values 24 25
[90]
THLE BIRC2
Mean 47.5
Standard deviation 12
Values 56 39
[91]
liver BIRC2
Mean 23.6
Standard deviation 3.9
Values 25 25 27 18
[92]
ref_hepatocyte SHARPIN
Mean 9.77
Standard deviation 5.2
Values 4.1 4.3 15 12 13
[93]
HepG2 SHARPIN
Mean 17.9
Standard deviation 2.9
Values 20 16
[94]
HepG2.C3A SHARPIN
Mean 14.4
Standard deviation 3.7
Values 17 12
[95]
HuH.7 SHARPIN
Mean 14.1
Standard deviation 2.2
Values 14 12 16
[96]
SNU475 SHARPIN
Mean 19.1
Standard deviation 1.6
Values 20 18
[97]
THLE SHARPIN
Mean 14.8
Standard deviation 0.22
Values 15 15
[98]
liver SHARPIN
Mean 11.3
Standard deviation 7
Values 19 4.7 15 6.2
[99]
ref_hepatocyte TAB2
Mean 9.62
Standard deviation 3.5
Values 7.9 8.1 16 8.4 7.8
[100]
HepG2 TAB2
Mean 27.4
Standard deviation 8.1
Values 22 33
[101]
HepG2.C3A TAB2
Mean 27.3
Standard deviation 2.5
Values 29 26
[102]
HuH.7 TAB2
Mean 31.5
Standard deviation 8.5
Values 28 41 25
[103]
SNU475 TAB2
Mean 57.4
Standard deviation 2.2
Values 59 56
[104]
THLE TAB2
Mean 44.2
Standard deviation 0.52
Values 44 45
[105]
liver TAB2
Mean 16.2
Standard deviation 4.7
Values 21 15 10 19
[106]
ref_hepatocyte FADD
Mean 9.28
Standard deviation 6.6
Values 3.8 12 20 6.3 5.1
[107]
HepG2 FADD
Mean 21.1
Standard deviation 4.6
Values 24 18
[108]
HepG2.C3A FADD
Mean 11.5
Standard deviation 1.6
Values 10 13
[109]
HuH.7 FADD
Mean 18.2
Standard deviation 3.2
Values 16 16 22
[110]
SNU475 FADD
Mean 65.1
Standard deviation 11
Values 73 58
[111]
THLE FADD
Mean 16
Standard deviation 3.5
Values 14 19
[112]
liver FADD
Mean 3.86
Standard deviation 1.3
Values 2.5 4.9 3 5.1
[113]
ref_hepatocyte CASP8
Mean 8.88
Standard deviation 6.8
Values 18 13 8.9 1.9 2.8
[114]
HepG2 CASP8
Mean 19.9
Standard deviation 3.1
Values 22 18
[115]
HepG2.C3A CASP8
Mean 26.3
Standard deviation 13
Values 17 35
[116]
HuH.7 CASP8
Mean 14.2
Standard deviation 3.6
Values 14 11 18
[117]
SNU475 CASP8
Mean 15.4
Standard deviation 0.7
Values 16 15
[118]
THLE CASP8
Mean 10.3
Standard deviation 0.97
Values 9.6 11
[119]
liver CASP8
Mean 4.72
Standard deviation 0.87
Values 3.4 5.2 5.3 5
[120]
ref_hepatocyte MAP3K7
Mean 8.64
Standard deviation 6.6
Values 18 13 4.6 4 3.6
[121]
HepG2 MAP3K7
Mean 17.8
Standard deviation 6.7
Values 13 23
[122]
HepG2.C3A MAP3K7
Mean 33.3
Standard deviation 3
Values 31 35
[123]
HuH.7 MAP3K7
Mean 29.2
Standard deviation 2.3
Values 31 27 30
[124]
SNU475 MAP3K7
Mean 22.3
Standard deviation 2.2
Values 24 21
[125]
THLE MAP3K7
Mean 28.3
Standard deviation 1.5
Values 29 27
[126]
liver MAP3K7
Mean 14.6
Standard deviation 1.8
Values 14 16 16 12
[127]
ref_hepatocyte TRAF1
Mean 7.51
Standard deviation 9.8
Values 0.064 17 19 0.39 0.64
[128]
HepG2 TRAF1
Mean 0.773
Standard deviation 0.67
Values 1.2 0.3
[129]
HepG2.C3A TRAF1
Mean 0.631
Standard deviation 0.33
Values 0.87 0.4
[130]
HuH.7 TRAF1
Mean 1.09
Standard deviation 0.11
Values 0.96 1.2 1.1
[131]
SNU475 TRAF1
Mean 1.19
Standard deviation 0.16
Values 1.1 1.3
[132]
THLE TRAF1
Mean 1.97
Standard deviation 0.35
Values 1.7 2.2
[133]
liver TRAF1
Mean 1.43
Standard deviation 0.57
Values 0.89 1.7 1.1 2.1
[134]
ref_hepatocyte TAB3
Mean 6.67
Standard deviation 6.1
Values 17 5.7 5.5 1.9 3.1
[135]
HepG2 TAB3
Mean 15.3
Standard deviation 7.1
Values 10 20
[136]
HepG2.C3A TAB3
Mean 52.5
Standard deviation 9.3
Values 59 46
[137]
HuH.7 TAB3
Mean 53.9
Standard deviation 32
Values 42 90 30
[138]
SNU475 TAB3
Mean 15.6
Standard deviation 5
Values 19 12
[139]
THLE TAB3
Mean 40.2
Standard deviation 2.3
Values 42 39
[140]
liver TAB3
Mean 16.8
Standard deviation 3.6
Values 21 18 15 13
[141]
ref_hepatocyte TRADD
Mean 5.53
Standard deviation 1.5
Values 3.6 4.8 5.3 7.4 6.5
[142]
HepG2 TRADD
Mean 10.2
Standard deviation 3.2
Values 12 8
[143]
HepG2.C3A TRADD
Mean 8.12
Standard deviation 2.3
Values 9.8 6.5
[144]
HuH.7 TRADD
Mean 3.47
Standard deviation 1.2
Values 2.9 2.7 4.9
[145]
SNU475 TRADD
Mean 5.13
Standard deviation 1
Values 5.8 4.4
[146]
THLE TRADD
Mean 5.18
Standard deviation 0.33
Values 4.9 5.4
[147]
liver TRADD
Mean 5.22
Standard deviation 3
Values 9.2 2.7 6 3
[148]
ref_hepatocyte USP4
Mean 5.41
Standard deviation 1.7
Values 4.6 8.4 4.1 5.1 4.8
[149]
HepG2 USP4
Mean 13.6
Standard deviation 2.2
Values 12 15
[150]
HepG2.C3A USP4
Mean 16.9
Standard deviation 2.6
Values 15 19
[151]
HuH.7 USP4
Mean 9.64
Standard deviation 1.7
Values 12 8.3 9.1
[152]
SNU475 USP4
Mean 9.98
Standard deviation 1.4
Values 11 9
[153]
THLE USP4
Mean 22.1
Standard deviation 2.8
Values 20 24
[154]
liver USP4
Mean 13.6
Standard deviation 6.3
Values 14 11 22 6.9
[155]
ref_hepatocyte TRAF2
Mean 5.07
Standard deviation 4.4
Values 1.1 5.1 12 4.2 2.5
[156]
HepG2 TRAF2
Mean 13.1
Standard deviation 2.2
Values 15 12
[157]
HepG2.C3A TRAF2
Mean 12.2
Standard deviation 1.2
Values 13 11
[158]
HuH.7 TRAF2
Mean 9.75
Standard deviation 2.3
Values 9.4 7.6 12
[159]
SNU475 TRAF2
Mean 10.1
Standard deviation 0.75
Values 9.6 11
[160]
THLE TRAF2
Mean 11.4
Standard deviation 2.7
Values 9.5 13
[161]
liver TRAF2
Mean 4.15
Standard deviation 1.4
Values 4 2.6 6 4.1
[162]
ref_hepatocyte ADAM17
Mean 5.04
Standard deviation 4.3
Values 10 8.5 4.3 1 1.1
[163]
HepG2 ADAM17
Mean 17.8
Standard deviation 0.96
Values 18 17
[164]
HepG2.C3A ADAM17
Mean 14.6
Standard deviation 0.94
Values 14 15
[165]
HuH.7 ADAM17
Mean 11.7
Standard deviation 1.5
Values 13 12 10
[166]
SNU475 ADAM17
Mean 31
Standard deviation 2.8
Values 33 29
[167]
THLE ADAM17
Mean 19
Standard deviation 2.3
Values 17 21
[168]
liver ADAM17
Mean 7.57
Standard deviation 0.72
Values 7.2 8.6 7 7.4
[169]
ref_hepatocyte RIPK1
Mean 4.28
Standard deviation 0.89
Values 3.7 4.4 3.1 5.4 4.8
[170]
HepG2 RIPK1
Mean 11.5
Standard deviation 4
Values 8.7 14
[171]
HepG2.C3A RIPK1
Mean 11.5
Standard deviation 0.53
Values 11 12
[172]
HuH.7 RIPK1
Mean 8.85
Standard deviation 0.42
Values 8.4 9.3 8.8
[173]
SNU475 RIPK1
Mean 16.6
Standard deviation 2.9
Values 19 15
[174]
THLE RIPK1
Mean 13.4
Standard deviation 1
Values 13 14
[175]
liver RIPK1
Mean 17
Standard deviation 5.1
Values 12 21 13 22
[176]
ref_hepatocyte CYLD
Mean 4.19
Standard deviation 3.9
Values 1.9 11 5.5 1.5 1.6
[177]
HepG2 CYLD
Mean 8.62
Standard deviation 3.8
Values 5.9 11
[178]
HepG2.C3A CYLD
Mean 8.42
Standard deviation 0.26
Values 8.6 8.2
[179]
HuH.7 CYLD
Mean 3.55
Standard deviation 1.5
Values 2.9 5.2 2.6
[180]
SNU475 CYLD
Mean 14.8
Standard deviation 2.6
Values 17 13
[181]
THLE CYLD
Mean 38.9
Standard deviation 5.8
Values 43 35
[182]
liver CYLD
Mean 22.8
Standard deviation 4.7
Values 22 26 17 27
[183]
ref_hepatocyte RNF31
Mean 4.01
Standard deviation 1.4
Values 5.8 2.3 5.1 3.2 3.8
[184]
HepG2 RNF31
Mean 48.2
Standard deviation 2.9
Values 50 46
[185]
HepG2.C3A RNF31
Mean 12.4
Standard deviation 0.53
Values 12 13
[186]
HuH.7 RNF31
Mean 20.6
Standard deviation 2
Values 23 21 19
[187]
SNU475 RNF31
Mean 16
Standard deviation 0.43
Values 16 16
[188]
THLE RNF31
Mean 13.5
Standard deviation 0.0054
Values 13 13
[189]
liver RNF31
Mean 12
Standard deviation 0.42
Values 12 12 12 13
[190]
ref_hepatocyte CHUK
Mean 3.93
Standard deviation 1.2
Values 4.2 5.7 2.3 3.4 4.1
[191]
HepG2 CHUK
Mean 16.2
Standard deviation 6.4
Values 12 21
[192]
HepG2.C3A CHUK
Mean 33.6
Standard deviation 13
Values 25 43
[193]
HuH.7 CHUK
Mean 31.4
Standard deviation 3.3
Values 34 28 32
[194]
SNU475 CHUK
Mean 11.3
Standard deviation 1.1
Values 11 12
[195]
THLE CHUK
Mean 22.3
Standard deviation 0.15
Values 22 22
[196]
liver CHUK
Mean 16
Standard deviation 3.3
Values 13 21 15 15
[197]
ref_hepatocyte TAB1
Mean 3.61
Standard deviation 1.3
Values 2.3 2.1 5.1 4.4 4.1
[198]
HepG2 TAB1
Mean 12.5
Standard deviation 0.3
Values 13 12
[199]
HepG2.C3A TAB1
Mean 17.4
Standard deviation 1.8
Values 19 16
[200]
HuH.7 TAB1
Mean 17.6
Standard deviation 2.2
Values 19 15 19
[201]
SNU475 TAB1
Mean 6.68
Standard deviation 1.2
Values 7.5 5.8
[202]
THLE TAB1
Mean 9.45
Standard deviation 1.6
Values 8.3 11
[203]
liver TAB1
Mean 5.99
Standard deviation 1.7
Values 7.6 4.1 7.1 5.1
[204]
ref_hepatocyte IKBKB
Mean 3.48
Standard deviation 0.8
Values 2.9 4.3 4.2 3.5 2.5
[205]
HepG2 IKBKB
Mean 11
Standard deviation 0.46
Values 11 11
[206]
HepG2.C3A IKBKB
Mean 10.2
Standard deviation 1
Values 11 9.5
[207]
HuH.7 IKBKB
Mean 10.6
Standard deviation 1.9
Values 11 8.4 12
[208]
SNU475 IKBKB
Mean 7.65
Standard deviation 1.8
Values 8.9 6.4
[209]
THLE IKBKB
Mean 9.14
Standard deviation 0.21
Values 9.3 9
[210]
liver IKBKB
Mean 11.2
Standard deviation 0.34
Values 11 11 11 12
[211]
ref_hepatocyte BAG4
Mean 3.32
Standard deviation 2
Values 6.1 2.8 1.3 1.9 4.5
[212]
HepG2 BAG4
Mean 9.37
Standard deviation 4
Values 6.5 12
[213]
HepG2.C3A BAG4
Mean 16.1
Standard deviation 2.4
Values 14 18
[214]
HuH.7 BAG4
Mean 38.1
Standard deviation 6.2
Values 44 32 38
[215]
SNU475 BAG4
Mean 5.84
Standard deviation 0.0067
Values 5.8 5.8
[216]
THLE BAG4
Mean 7.64
Standard deviation 0.45
Values 8 7.3
[217]
liver BAG4
Mean 16.6
Standard deviation 6.8
Values 21 11 24 11
[218]
ref_hepatocyte NSMAF
Mean 3.03
Standard deviation 1.7
Values 4.9 3.8 4.1 1.2 1.2
[219]
HepG2 NSMAF
Mean 11.8
Standard deviation 2.5
Values 10 14
[220]
HepG2.C3A NSMAF
Mean 9.85
Standard deviation 1.2
Values 9 11
[221]
HuH.7 NSMAF
Mean 1.74
Standard deviation 0.28
Values 1.9 1.9 1.4
[222]
SNU475 NSMAF
Mean 23
Standard deviation 1.4
Values 24 22
[223]
THLE NSMAF
Mean 15.2
Standard deviation 2.3
Values 14 17
[224]
liver NSMAF
Mean 4.87
Standard deviation 0.54
Values 4.6 5.7 4.8 4.5
[225]
ref_hepatocyte OTUD7B
Mean 2.95
Standard deviation 1.5
Values 3.2 4.9 3.8 1.2 1.7
[226]
HepG2 OTUD7B
Mean 13.7
Standard deviation 0.66
Values 13 14
[227]
HepG2.C3A OTUD7B
Mean 9.08
Standard deviation 0.14
Values 9 9.2
[228]
HuH.7 OTUD7B
Mean 11.6
Standard deviation 2.9
Values 12 14 8.4
[229]
SNU475 OTUD7B
Mean 23
Standard deviation 2.1
Values 24 21
[230]
THLE OTUD7B
Mean 17.6
Standard deviation 2.7
Values 16 20
[231]
liver OTUD7B
Mean 11.2
Standard deviation 8.3
Values 4.3 19 3.7 18
[232]
ref_hepatocyte SMPD2
Mean 2.83
Standard deviation 2.4
Values 0.63 1.8 6.8 3.1 1.8
[233]
HepG2 SMPD2
Mean 3.24
Standard deviation 0.12
Values 3.3 3.1
[234]
HepG2.C3A SMPD2
Mean 3.63
Standard deviation 0.1
Values 3.6 3.7
[235]
HuH.7 SMPD2
Mean 2.28
Standard deviation 0.65
Values 2.3 1.6 2.9
[236]
SNU475 SMPD2
Mean 1.52
Standard deviation 0.34
Values 1.3 1.8
[237]
THLE SMPD2
Mean 3.71
Standard deviation 0.59
Values 3.3 4.1
[238]
liver SMPD2
Mean 1.32
Standard deviation 0.52
Values 2 0.78 1.5 1
[239]
ref_hepatocyte XIAP
Mean 2.63
Standard deviation 0.63
Values 2.6 3.3 2.1 1.9 3.2
[240]
HepG2 XIAP
Mean 16.7
Standard deviation 3.8
Values 14 19
[241]
HepG2.C3A XIAP
Mean 22.3
Standard deviation 5.6
Values 18 26
[242]
HuH.7 XIAP
Mean 29.4
Standard deviation 6.2
Values 34 31 22
[243]
SNU475 XIAP
Mean 29.2
Standard deviation 5.9
Values 33 25
[244]
THLE XIAP
Mean 21.9
Standard deviation 3.4
Values 19 24
[245]
liver XIAP
Mean 24
Standard deviation 7.9
Values 19 34 16 27
[246]
ref_hepatocyte SPPL2B
Mean 2.5
Standard deviation 1.3
Values 1.8 0.96 2 3.7 4.1
[247]
HepG2 SPPL2B
Mean 13.4
Standard deviation 1.1
Values 14 13
[248]
HepG2.C3A SPPL2B
Mean 14.3
Standard deviation 4
Values 17 11
[249]
HuH.7 SPPL2B
Mean 18.5
Standard deviation 3.8
Values 20 14 21
[250]
SNU475 SPPL2B
Mean 6.39
Standard deviation 1.4
Values 7.4 5.4
[251]
THLE SPPL2B
Mean 11.9
Standard deviation 1.9
Values 13 11
[252]
liver SPPL2B
Mean 8.38
Standard deviation 1.6
Values 8.8 6.2 10 8.5
[253]
ref_hepatocyte USP21
Mean 1.92
Standard deviation 0.82
Values 2.6 0.48 2.2 2.2 2.1
[254]
HepG2 USP21
Mean 8.86
Standard deviation 0.64
Values 9.3 8.4
[255]
HepG2.C3A USP21
Mean 8.76
Standard deviation 1.2
Values 9.6 7.9
[256]
HuH.7 USP21
Mean 7.91
Standard deviation 1.1
Values 8.5 6.6 8.5
[257]
SNU475 USP21
Mean 10
Standard deviation 1.7
Values 11 8.9
[258]
THLE USP21
Mean 9.23
Standard deviation 1
Values 8.5 10
[259]
liver USP21
Mean 2.8
Standard deviation 0.83
Values 3.2 2.1 3.8 2.1
[260]
ref_hepatocyte MADD
Mean 1.88
Standard deviation 0.3
Values 2.2 1.5 1.9 2.2 1.7
[261]
HepG2 MADD
Mean 24.4
Standard deviation 0.88
Values 25 24
[262]
HepG2.C3A MADD
Mean 19.8
Standard deviation 2
Values 21 18
[263]
HuH.7 MADD
Mean 25.4
Standard deviation 2.5
Values 28 24 24
[264]
SNU475 MADD
Mean 14.7
Standard deviation 1.3
Values 14 16
[265]
THLE MADD
Mean 13.3
Standard deviation 1.2
Values 13 14
[266]
liver MADD
Mean 15.8
Standard deviation 1.9
Values 16 18 13 16
[267]
ref_hepatocyte USP2
Mean 1.28
Standard deviation 0.47
Values 1.7 1.4 1.2 1.6 0.52
[268]
HepG2 USP2
Mean 6.54
Standard deviation 0.021
Values 6.5 6.6
[269]
HepG2.C3A USP2
Mean 4.63
Standard deviation 0.13
Values 4.7 4.5
[270]
HuH.7 USP2
Mean 2.26
Standard deviation 0.065
Values 2.2 2.2 2.3
[271]
SNU475 USP2
Mean 1.92
Standard deviation 0.082
Values 2 1.9
[272]
THLE USP2
Mean 0.761
Standard deviation 0.26
Values 0.58 0.94
[273]
liver USP2
Mean 1.98
Standard deviation 0.74
Values 2.7 0.96 2.3 2
[274]
ref_hepatocyte SMPD3
Mean 0.464
Standard deviation 0.66
Values 0 0 0 0.93 1.4
[275]
HepG2 SMPD3
Mean 1.11
Standard deviation 1
Values 1.8 0.37
[276]
HepG2.C3A SMPD3
Mean 1.38
Standard deviation 0.73
Values 1.9 0.86
[277]
HuH.7 SMPD3
Mean 0.793
Standard deviation 0.28
Values 0.62 0.64 1.1
[278]
SNU475 SMPD3
Mean 1.07
Standard deviation 0.15
Values 1.2 0.97
[279]
THLE SMPD3
Mean 0.63
Standard deviation 0.36
Values 0.88 0.38
[280]
liver SMPD3
Mean 5.01
Standard deviation 3.1
Values 1.4 5.6 4.2 8.8
[281]
ref_hepatocyte CLIP3
Mean 0.15
Standard deviation 0.15
Values 0 0.31 0.12 0.29 0.024
[282]
HepG2 CLIP3
Mean 0.378
Standard deviation 0.073
Values 0.43 0.33
[283]
HepG2.C3A CLIP3
Mean 0.768
Standard deviation 0.78
Values 1.3 0.21
[284]
HuH.7 CLIP3
Mean 0.779
Standard deviation 0.43
Values 0.48 1.3 0.58
[285]
SNU475 CLIP3
Mean 0.574
Standard deviation 0.24
Values 0.75 0.4
[286]
THLE CLIP3
Mean 13.2
Standard deviation 0.51
Values 13 14
[287]
liver CLIP3
Mean 0.463
Standard deviation 0.36
Values 0.82 0.086 0.72 0.23
[288]
ref_hepatocyte TNF
Mean 0.113
Standard deviation 0.17
Values 0 0 0 0.17 0.39
[289]
HepG2 TNF
Mean 0.533
Standard deviation 0.44
Values 0.84 0.22
[290]
HepG2.C3A TNF
Mean 0.108
Standard deviation 0.029
Values 0.087 0.13
[291]
HuH.7 TNF
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[292]
SNU475 TNF
Mean 0.0443
Standard deviation 0.023
Values 0.028 0.061
[293]
THLE TNF
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[294]
liver TNF
Mean 0.0431
Standard deviation 0.06
Values 0 0.014 0.026 0.13
[295]
ref_hepatocyte RACK1
Missing
[296]
HepG2 RACK1
Missing
[297]
HepG2.C3A RACK1
Missing
[298]
HuH.7 RACK1
Missing
[299]
SNU475 RACK1
Missing
[300]
THLE RACK1
Missing
[301]
liver RACK1
Missing
[302]
ref_hepatocyte OTULIN
Missing
[303]
HepG2 OTULIN
Missing
[304]
HepG2.C3A OTULIN
Missing
[305]
HuH.7 OTULIN
Missing
[306]
SNU475 OTULIN
Missing
[307]
THLE OTULIN
Missing
[308]
liver OTULIN
Missing