REACTOME_TNF_RECEPTOR_SUPERFAMILY_TNFSF_MEMBERS_MEDIATING_NON_CANONICAL_NF_KB_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 TNFRSF12A Tumor necrosis factor receptor superfamily member 12A [1] 0.04[2] -0.37[3] -1.49[4] -0.46[5] -0.64[6] -2.67[7]
2 LTBR Tumor necrosis factor receptor superfamily member 3 [8] -0.41[9] -0.80[10] 0.72[11] -0.05[12] -0.18[13] 0.66[14]
3 BIRC3 Baculoviral IAP repeat-containing protein 3 [15] -2.55[16] -1.52[17] -3.03[18] -2.40[19] 0.62[20] -1.63[21]
4 BIRC2 Baculoviral IAP repeat-containing protein 2 [22] 0.81[23] 1.77[24] 1.61[25] 1.13[26] 1.18[27] 1.17[28]
5 TRAF2 TNF receptor-associated factor 2 [29] 0.80[30] 0.86[31] 1.48[32] 0.84[33] 0.10[34] -0.35[35]
6 CD40 Tumor necrosis factor receptor superfamily member 5 [36] -0.24[37] -1.42[38] -8.79[39] -2.10[40] -1.52[41] -0.49[42]
7 TNFSF14 Tumor necrosis factor ligand superfamily member 14 [43] -3.95[44] 0.40[45] -3.57[46] -4.58[47] -3.72[48] 2.43[49]
8 TNFSF12 Tumor necrosis factor ligand superfamily member 12 [50] -1.08[51] 0.46[52] -2.96[53] -1.20[54] -1.28[55] -1.03[56]
9 TNFSF11 Tumor necrosis factor ligand superfamily member 11 [57] [58] [59] [60] -9.82[61] -5.08[62] -3.31[63]
10 MAP3K14 Mitogen-activated protein kinase kinase kinase 14 [64] 0.17[65] 0.63[66] 0.35[67] 2.79[68] 1.03[69] 1.33[70]
11 TRAF3 TNF receptor-associated factor 3 [71] 3.45[72] 2.88[73] 3.37[74] 3.55[75] 3.21[76] 2.37[77]
12 LTB Lymphotoxin-beta [78] -1.19[79] -1.46[80] -4.81[81] -3.93[82] -5.81[83] -2.35[84]
13 TNFRSF11A Tumor necrosis factor receptor superfamily member 11A [85] 2.61[86] 1.40[87] 0.43[88] 0.09[89] 0.67[90] -0.80[91]
14 TNFSF13B Tumor necrosis factor ligand superfamily member 13B [92] -5.33[93] -2.34[94] -2.58[95] -0.35[96] 0.36[97] 3.28[98]
15 CD40LG CD40 ligand [99] -4.21[100] [101] -4.97[102] -3.52[103] [104] -0.13[105]
16 LTA Lymphotoxin-alpha [106] -2.81[107] [108] -1.49[109] -0.14[110] -3.14[111] -1.39[112]
17 TNFRSF13C Tumor necrosis factor receptor superfamily member 13C [113] [114] [115] [116] [117] [118] [119]
[1]
ref_hepatocyte TNFRSF12A
Mean 52.6
Standard deviation 71
Values 11 41 1.8e+02 32 1.5
[2]
HepG2 TNFRSF12A
Mean 80.4
Standard deviation 23
Values 96 65
[3]
HepG2.C3A TNFRSF12A
Mean 53.5
Standard deviation 8.3
Values 59 48
[4]
HuH.7 TNFRSF12A
Mean 12.9
Standard deviation 3.5
Values 9.1 16 13
[5]
SNU475 TNFRSF12A
Mean 42.6
Standard deviation 8.9
Values 36 49
[6]
THLE TNFRSF12A
Mean 70.7
Standard deviation 15
Values 60 81
[7]
liver TNFRSF12A
Mean 8.63
Standard deviation 11
Values 3.8 4.5 25 1.5
[8]
ref_hepatocyte LTBR
Mean 30.5
Standard deviation 23
Values 4.3 17 39 64 29
[9]
HepG2 LTBR
Mean 34.3
Standard deviation 5.2
Values 38 31
[10]
HepG2.C3A LTBR
Mean 23.1
Standard deviation 7.8
Values 29 18
[11]
HuH.7 LTBR
Mean 34.5
Standard deviation 1.9
Values 33 34 36
[12]
SNU475 LTBR
Mean 32.9
Standard deviation 3.1
Values 35 31
[13]
THLE LTBR
Mean 56.6
Standard deviation 5.3
Values 53 60
[14]
liver LTBR
Mean 50.3
Standard deviation 31
Values 69 22 84 26
[15]
ref_hepatocyte BIRC3
Mean 15.6
Standard deviation 19
Values 1.2 29 43 1.5 3.2
[16]
HepG2 BIRC3
Mean 3.98
Standard deviation 0.49
Values 4.3 3.6
[17]
HepG2.C3A BIRC3
Mean 7.2
Standard deviation 0.46
Values 6.9 7.5
[18]
HuH.7 BIRC3
Mean 1.31
Standard deviation 1.3
Values 0.65 2.8 0.49
[19]
SNU475 BIRC3
Mean 3.3
Standard deviation 0.79
Values 2.7 3.9
[20]
THLE BIRC3
Mean 50.3
Standard deviation 18
Values 63 37
[21]
liver BIRC3
Mean 5.25
Standard deviation 1.9
Values 5.1 5 3.2 7.7
[22]
ref_hepatocyte BIRC2
Mean 10
Standard deviation 3.6
Values 13 14 11 6.4 5.8
[23]
HepG2 BIRC2
Mean 26.2
Standard deviation 3.4
Values 24 29
[24]
HepG2.C3A BIRC2
Mean 45.2
Standard deviation 3.6
Values 43 48
[25]
HuH.7 BIRC2
Mean 21
Standard deviation 4
Values 18 25 20
[26]
SNU475 BIRC2
Mean 24.6
Standard deviation 0.14
Values 24 25
[27]
THLE BIRC2
Mean 47.5
Standard deviation 12
Values 56 39
[28]
liver BIRC2
Mean 23.6
Standard deviation 3.9
Values 25 25 27 18
[29]
ref_hepatocyte TRAF2
Mean 5.07
Standard deviation 4.4
Values 1.1 5.1 12 4.2 2.5
[30]
HepG2 TRAF2
Mean 13.1
Standard deviation 2.2
Values 15 12
[31]
HepG2.C3A TRAF2
Mean 12.2
Standard deviation 1.2
Values 13 11
[32]
HuH.7 TRAF2
Mean 9.75
Standard deviation 2.3
Values 9.4 7.6 12
[33]
SNU475 TRAF2
Mean 10.1
Standard deviation 0.75
Values 9.6 11
[34]
THLE TRAF2
Mean 11.4
Standard deviation 2.7
Values 9.5 13
[35]
liver TRAF2
Mean 4.15
Standard deviation 1.4
Values 4 2.6 6 4.1
[36]
ref_hepatocyte CD40
Mean 4.89
Standard deviation 3.8
Values 0 1.6 8.5 7.1 7.3
[37]
HepG2 CD40
Mean 6.2
Standard deviation 2.8
Values 8.2 4.2
[38]
HepG2.C3A CD40
Mean 2.41
Standard deviation 0.21
Values 2.6 2.3
[39]
HuH.7 CD40
Mean 0.00761
Standard deviation 0.0083
Values 0.016 0.0064 0
[40]
SNU475 CD40
Mean 1.27
Standard deviation 0.3
Values 1.1 1.5
[41]
THLE CD40
Mean 3.58
Standard deviation 1.1
Values 4.4 2.8
[42]
liver CD40
Mean 3.64
Standard deviation 2.1
Values 4.1 2 6.4 2.1
[43]
ref_hepatocyte TNFSF14
Mean 4.67
Standard deviation 4.7
Values 0.8 0.43 3.7 6.4 12
[44]
HepG2 TNFSF14
Mean 0.45
Standard deviation 0.085
Values 0.51 0.39
[45]
HepG2.C3A TNFSF14
Mean 8.16
Standard deviation 4.2
Values 11 5.2
[46]
HuH.7 TNFSF14
Mean 0.27
Standard deviation 0.041
Values 0.26 0.31 0.23
[47]
SNU475 TNFSF14
Mean 0.218
Standard deviation 0.0069
Values 0.22 0.21
[48]
THLE TNFSF14
Mean 0.742
Standard deviation 0.43
Values 1 0.44
[49]
liver TNFSF14
Mean 26.1
Standard deviation 15
Values 7.4 31 23 43
[50]
ref_hepatocyte TNFSF12
Mean 2.36
Standard deviation 1.2
Values 2.2 1.4 1.3 4.2 2.7
[51]
HepG2 TNFSF12
Mean 1.66
Standard deviation 0.54
Values 2 1.3
[52]
HepG2.C3A TNFSF12
Mean 4.28
Standard deviation 2.6
Values 6.1 2.5
[53]
HuH.7 TNFSF12
Mean 0.208
Standard deviation 0.075
Values 0.14 0.29 0.2
[54]
SNU475 TNFSF12
Mean 1.15
Standard deviation 0.57
Values 1.6 0.75
[55]
THLE TNFSF12
Mean 2.04
Standard deviation 0.14
Values 1.9 2.1
[56]
liver TNFSF12
Mean 1.2
Standard deviation 0.85
Values 2.4 0.5 1.4 0.61
[57]
ref_hepatocyte TNFSF11
Mean 2.05
Standard deviation 2.8
Values 0.099 6.4 3.2 0.32 0.22
[58]
HepG2 TNFSF11
Mean 0
Standard deviation 0
Values 0 0
[59]
HepG2.C3A TNFSF11
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 TNFSF11
Mean 0
Standard deviation 0
Values 0 0 0
[61]
SNU475 TNFSF11
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[62]
THLE TNFSF11
Mean 0.127
Standard deviation 0.029
Values 0.15 0.11
[63]
liver TNFSF11
Mean 0.215
Standard deviation 0.11
Values 0.31 0.27 0.23 0.053
[64]
ref_hepatocyte MAP3K14
Mean 1.9
Standard deviation 1.1
Values 0.92 2.2 3.6 1.7 1.1
[65]
HepG2 MAP3K14
Mean 3.19
Standard deviation 0.37
Values 3.4 2.9
[66]
HepG2.C3A MAP3K14
Mean 3.89
Standard deviation 0.18
Values 4 3.8
[67]
HuH.7 MAP3K14
Mean 1.66
Standard deviation 0.35
Values 1.3 1.9 1.8
[68]
SNU475 MAP3K14
Mean 14.7
Standard deviation 3
Values 13 17
[69]
THLE MAP3K14
Mean 8.14
Standard deviation 0.86
Values 8.8 7.5
[70]
liver MAP3K14
Mean 4.97
Standard deviation 1.7
Values 2.9 4.3 6.3 6.4
[71]
ref_hepatocyte TRAF3
Mean 1.27
Standard deviation 0.83
Values 0.98 2.5 1.7 0.56 0.6
[72]
HepG2 TRAF3
Mean 20.8
Standard deviation 3.9
Values 24 18
[73]
HepG2.C3A TRAF3
Mean 12.4
Standard deviation 0.058
Values 12 12
[74]
HuH.7 TRAF3
Mean 9.05
Standard deviation 1.3
Values 10 8.7 7.9
[75]
SNU475 TRAF3
Mean 16.6
Standard deviation 0.54
Values 17 16
[76]
THLE TRAF3
Mean 24.7
Standard deviation 3.8
Values 22 27
[77]
liver TRAF3
Mean 6.87
Standard deviation 4
Values 4.4 9.3 2.6 11
[78]
ref_hepatocyte LTB
Mean 0.989
Standard deviation 0.94
Values 0 0.14 1.6 1 2.2
[79]
HepG2 LTB
Mean 0.645
Standard deviation 0.34
Values 0.88 0.41
[80]
HepG2.C3A LTB
Mean 0.476
Standard deviation 0.23
Values 0.64 0.31
[81]
HuH.7 LTB
Mean 0.0242
Standard deviation 0.015
Values 0.041 0.013 0.019
[82]
SNU475 LTB
Mean 0.0724
Standard deviation 0.0092
Values 0.079 0.066
[83]
THLE LTB
Mean 0.037
Standard deviation 0.015
Values 0.047 0.027
[84]
liver LTB
Mean 0.203
Standard deviation 0.21
Values 0.49 0.071 0.21 0.04
[85]
ref_hepatocyte TNFRSF11A
Mean 0.838
Standard deviation 1.1
Values 1.8 0.15 2.2 0.052 0.024
[86]
HepG2 TNFRSF11A
Mean 7.65
Standard deviation 0.84
Values 7.1 8.2
[87]
HepG2.C3A TNFRSF11A
Mean 2.91
Standard deviation 0.61
Values 2.5 3.3
[88]
HuH.7 TNFRSF11A
Mean 0.777
Standard deviation 0.16
Values 0.77 0.62 0.94
[89]
SNU475 TNFRSF11A
Mean 0.995
Standard deviation 0.25
Values 1.2 0.82
[90]
THLE TNFRSF11A
Mean 2.8
Standard deviation 0.56
Values 2.4 3.2
[91]
liver TNFRSF11A
Mean 0.503
Standard deviation 0.29
Values 0.28 0.78 0.23 0.71
[92]
ref_hepatocyte TNFSF13B
Mean 0.308
Standard deviation 0.22
Values 0 0.44 0.32 0.22 0.57
[93]
HepG2 TNFSF13B
Mean 0.0114
Standard deviation 0.0081
Values 0.0057 0.017
[94]
HepG2.C3A TNFSF13B
Mean 0.0803
Standard deviation 0.038
Values 0.11 0.054
[95]
HuH.7 TNFSF13B
Mean 0.0355
Standard deviation 0.028
Values 0.033 0.064 0.0094
[96]
SNU475 TNFSF13B
Mean 0.27
Standard deviation 0.027
Values 0.25 0.29
[97]
THLE TNFSF13B
Mean 0.827
Standard deviation 0.1
Values 0.9 0.76
[98]
liver TNFSF13B
Mean 3.12
Standard deviation 1.7
Values 3.5 2.1 5.4 1.5
[99]
ref_hepatocyte CD40LG
Mean 0.0976
Standard deviation 0.22
Values 0 0 0 0 0.49
[100]
HepG2 CD40LG
Mean 0.00788
Standard deviation 0.0051
Values 0.011 0.0043
[101]
HepG2.C3A CD40LG
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 CD40LG
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[103]
SNU475 CD40LG
Mean 0.00949
Standard deviation 0.0063
Values 0.014 0.0051
[104]
THLE CD40LG
Mean 0
Standard deviation 0
Values 0 0
[105]
liver CD40LG
Mean 0.0927
Standard deviation 0.034
Values 0.047 0.13 0.1 0.093
[106]
ref_hepatocyte LTA
Mean 0.0472
Standard deviation 0.11
Values 0 0 0 0 0.24
[107]
HepG2 LTA
Mean 0.01
Standard deviation 0.002
Values 0.011 0.0086
[108]
HepG2.C3A LTA
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 LTA
Mean 0.0115
Standard deviation 0.015
Values 0 0.0064 0.028
[110]
SNU475 LTA
Mean 0.0479
Standard deviation 0.061
Values 0.0046 0.091
[111]
THLE LTA
Mean 0.0112
Standard deviation 0.00084
Values 0.012 0.011
[112]
liver LTA
Mean 0.0187
Standard deviation 0.024
Values 0.024 0 0.051 0
[113]
ref_hepatocyte TNFRSF13C
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[114]
HepG2 TNFRSF13C
Mean 0.0652
Standard deviation 0.038
Values 0.092 0.039
[115]
HepG2.C3A TNFRSF13C
Mean 0.0545
Standard deviation 0.047
Values 0.087 0.021
[116]
HuH.7 TNFRSF13C
Mean 0.104
Standard deviation 0.019
Values 0.11 0.083 0.12
[117]
SNU475 TNFRSF13C
Mean 0.0116
Standard deviation 0.016
Values 0.023 0
[118]
THLE TNFRSF13C
Mean 0.0443
Standard deviation 0.013
Values 0.035 0.053
[119]
liver TNFRSF13C
Mean 0
Standard deviation 0
Values 0 0 0 0