REACTOME_TLR3_MEDIATED_TICAM1_DEPENDENT_PROGRAMMED_CELL_DEATH Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 FADD FAS-associated death domain protein [1] 0.13[2] -0.56[3] 0.27[4] 0.96[5] -0.08[6] -1.52[7]
2 CASP8 Caspase-8 [8] 0.11[9] 0.70[10] -0.02[11] -1.05[12] -0.65[13] -1.16[14]
3 TICAM1 TIR domain-containing adapter molecule 1 [15] -0.62[16] -1.71[17] -0.66[18] -2.19[19] 0.00[20] -0.25[21]
4 RIPK1 Receptor-interacting serine/threonine-protein kinase 1 [22] 0.38[23] 0.56[24] 0.35[25] 0.11[26] 0.78[27] 1.74[28]
5 TLR3 Toll-like receptor 3 [29] -3.75[30] -4.20[31] -4.41[32] -1.33[33] 0.89[34] 1.31[35]
6 RIPK3 Receptor-interacting serine/threonine-protein kinase 3 [36] -6.56[37] [38] -5.11[39] [40] -5.20[41] 0.81[42]
[1]
ref_hepatocyte FADD
Mean 9.28
Standard deviation 6.6
Values 3.8 12 20 6.3 5.1
[2]
HepG2 FADD
Mean 21.1
Standard deviation 4.6
Values 24 18
[3]
HepG2.C3A FADD
Mean 11.5
Standard deviation 1.6
Values 10 13
[4]
HuH.7 FADD
Mean 18.2
Standard deviation 3.2
Values 16 16 22
[5]
SNU475 FADD
Mean 65.1
Standard deviation 11
Values 73 58
[6]
THLE FADD
Mean 16
Standard deviation 3.5
Values 14 19
[7]
liver FADD
Mean 3.86
Standard deviation 1.3
Values 2.5 4.9 3 5.1
[8]
ref_hepatocyte CASP8
Mean 8.88
Standard deviation 6.8
Values 18 13 8.9 1.9 2.8
[9]
HepG2 CASP8
Mean 19.9
Standard deviation 3.1
Values 22 18
[10]
HepG2.C3A CASP8
Mean 26.3
Standard deviation 13
Values 17 35
[11]
HuH.7 CASP8
Mean 14.2
Standard deviation 3.6
Values 14 11 18
[12]
SNU475 CASP8
Mean 15.4
Standard deviation 0.7
Values 16 15
[13]
THLE CASP8
Mean 10.3
Standard deviation 0.97
Values 9.6 11
[14]
liver CASP8
Mean 4.72
Standard deviation 0.87
Values 3.4 5.2 5.3 5
[15]
ref_hepatocyte TICAM1
Mean 4.75
Standard deviation 6.4
Values 0 1.4 16 3.4 3
[16]
HepG2 TICAM1
Mean 6.41
Standard deviation 2.9
Values 8.5 4.3
[17]
HepG2.C3A TICAM1
Mean 2.66
Standard deviation 0.59
Values 3.1 2.2
[18]
HuH.7 TICAM1
Mean 4.87
Standard deviation 0.33
Values 5.2 4.5 4.9
[19]
SNU475 TICAM1
Mean 3.73
Standard deviation 0.28
Values 3.5 3.9
[20]
THLE TICAM1
Mean 8.64
Standard deviation 1.3
Values 7.7 9.5
[21]
liver TICAM1
Mean 4.77
Standard deviation 3.4
Values 7.9 1.4 7.4 2.3
[22]
ref_hepatocyte RIPK1
Mean 4.28
Standard deviation 0.89
Values 3.7 4.4 3.1 5.4 4.8
[23]
HepG2 RIPK1
Mean 11.5
Standard deviation 4
Values 8.7 14
[24]
HepG2.C3A RIPK1
Mean 11.5
Standard deviation 0.53
Values 11 12
[25]
HuH.7 RIPK1
Mean 8.85
Standard deviation 0.42
Values 8.4 9.3 8.8
[26]
SNU475 RIPK1
Mean 16.6
Standard deviation 2.9
Values 19 15
[27]
THLE RIPK1
Mean 13.4
Standard deviation 1
Values 13 14
[28]
liver RIPK1
Mean 17
Standard deviation 5.1
Values 12 21 13 22
[29]
ref_hepatocyte TLR3
Mean 1.04
Standard deviation 0.74
Values 0 2 0.89 0.97 1.3
[30]
HepG2 TLR3
Mean 0.16
Standard deviation 0.0012
Values 0.16 0.16
[31]
HepG2.C3A TLR3
Mean 0.103
Standard deviation 0.036
Values 0.078 0.13
[32]
HuH.7 TLR3
Mean 0.0792
Standard deviation 0.093
Values 0.033 0.19 0.019
[33]
SNU475 TLR3
Mean 1.48
Standard deviation 0.068
Values 1.5 1.4
[34]
THLE TLR3
Mean 3.51
Standard deviation 0.81
Values 4.1 2.9
[35]
liver TLR3
Mean 3.05
Standard deviation 0.49
Values 2.5 3.4 2.8 3.5
[36]
ref_hepatocyte RIPK3
Mean 0.227
Standard deviation 0.15
Values 0 0.37 0.33 0.15 0.29
[37]
HepG2 RIPK3
Mean 0.00501
Standard deviation 0.001
Values 0.0057 0.0043
[38]
HepG2.C3A RIPK3
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 RIPK3
Mean 0.0107
Standard deviation 0.019
Values 0 0.032 0
[40]
SNU475 RIPK3
Mean 0
Standard deviation 0
Values 0 0
[41]
THLE RIPK3
Mean 0.0112
Standard deviation 0.00084
Values 0.012 0.011
[42]
liver RIPK3
Mean 0.474
Standard deviation 0.21
Values 0.78 0.43 0.36 0.33