REACTOME_TICAM1_DEPENDENT_ACTIVATION_OF_IRF3_IRF7 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.12[2] -0.32[3] -0.42[4] -0.28[5] -0.10[6] 0.09[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] 0.33[16] 0.43[17] -0.05[18] 0.57[19] 0.28[20] 0.54[21]
4 UBA52 Ubiquitin-60S ribosomal protein L40 [22] 2.76[23] 2.66[24] 3.46[25] 1.97[26] 2.51[27] 1.31[28]
5 IRF7 Interferon regulatory factor 7 [29] -7.15[30] -6.16[31] -5.30[32] -0.65[33] -1.18[34] 1.90[35]
6 IRF3 Interferon regulatory factor 3 [36] 2.38[37] 2.54[38] 3.02[39] 2.85[40] 2.17[41] 0.79[42]
7 TANK TRAF family member-associated NF-kappa-B activator [43] 0.94[44] 2.92[45] 2.30[46] 2.62[47] 1.58[48] 2.50[49]
8 TBK1 Serine/threonine-protein kinase TBK1 [50] 1.45[51] 3.12[52] 2.02[53] 2.99[54] 2.80[55] 2.44[56]
9 TICAM1 TIR domain-containing adapter molecule 1 [57] 1.37[58] 0.26[59] 0.95[60] 1.27[61] 2.04[62] 1.47[63]
10 TRAF3 TNF receptor-associated factor 3 [64] 4.97[65] 4.38[66] 3.74[67] 5.33[68] 5.46[69] 3.89[70]
11 TLR3 Toll-like receptor 3 [71] -1.76[72] -2.23[73] -2.80[74] 2.13[75] 2.94[76] 3.02[77]
12 IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon [78] 3.80[79] 3.66[80] 2.31[81] 5.06[82] 4.33[83] 1.73[84]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[23]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[24]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[25]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[26]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[27]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[28]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[29]
ref_hepatocyte IRF7
Mean 11.7
Standard deviation 10
Values 0 3.4 11 20 24
[30]
HepG2 IRF7
Mean 0.0429
Standard deviation 0.012
Values 0.034 0.051
[31]
HepG2.C3A IRF7
Mean 0.0764
Standard deviation 0.0019
Values 0.078 0.075
[32]
HuH.7 IRF7
Mean 0.158
Standard deviation 0.13
Values 0.16 0.29 0.028
[33]
SNU475 IRF7
Mean 2.42
Standard deviation 0.34
Values 2.2 2.7
[34]
THLE IRF7
Mean 2.27
Standard deviation 0.44
Values 2 2.6
[35]
liver IRF7
Mean 15.8
Standard deviation 4.5
Values 16 9.6 20 18
[36]
ref_hepatocyte IRF3
Mean 10
Standard deviation 4.1
Values 7.1 4.7 13 15 10
[37]
HepG2 IRF3
Mean 27.2
Standard deviation 6.6
Values 32 23
[38]
HepG2.C3A IRF3
Mean 27.3
Standard deviation 1.4
Values 28 26
[39]
HuH.7 IRF3
Mean 43.3
Standard deviation 14
Values 47 28 54
[40]
SNU475 IRF3
Mean 23.5
Standard deviation 4.3
Values 20 27
[41]
THLE IRF3
Mean 19.9
Standard deviation 0.46
Values 20 20
[42]
liver IRF3
Mean 6.27
Standard deviation 2.8
Values 8.8 3.7 8.7 4
[43]
ref_hepatocyte TANK
Mean 8.63
Standard deviation 3.4
Values 7.4 6.5 5.3 10 14
[44]
HepG2 TANK
Mean 8.65
Standard deviation 2.2
Values 7.1 10
[45]
HepG2.C3A TANK
Mean 30.5
Standard deviation 0.31
Values 31 30
[46]
HuH.7 TANK
Mean 22.6
Standard deviation 1.7
Values 22 21 25
[47]
SNU475 TANK
Mean 17.3
Standard deviation 2.1
Values 19 16
[48]
THLE TANK
Mean 11.4
Standard deviation 0.54
Values 12 11
[49]
liver TANK
Mean 17.8
Standard deviation 10
Values 32 10 20 9.7
[50]
ref_hepatocyte TBK1
Mean 6.94
Standard deviation 1.7
Values 7.8 8.4 8.4 5 5.2
[51]
HepG2 TBK1
Mean 9.87
Standard deviation 3.8
Values 7.2 13
[52]
HepG2.C3A TBK1
Mean 28.1
Standard deviation 7.6
Values 23 33
[53]
HuH.7 TBK1
Mean 14.9
Standard deviation 0.71
Values 14 16 15
[54]
SNU475 TBK1
Mean 17.9
Standard deviation 1.5
Values 19 17
[55]
THLE TBK1
Mean 21.3
Standard deviation 2.3
Values 23 20
[56]
liver TBK1
Mean 13.7
Standard deviation 2.9
Values 13 15 17 10
[57]
ref_hepatocyte TICAM1
Mean 4.75
Standard deviation 6.4
Values 0 1.4 16 3.4 3
[58]
HepG2 TICAM1
Mean 6.41
Standard deviation 2.9
Values 8.5 4.3
[59]
HepG2.C3A TICAM1
Mean 2.66
Standard deviation 0.59
Values 3.1 2.2
[60]
HuH.7 TICAM1
Mean 4.87
Standard deviation 0.33
Values 5.2 4.5 4.9
[61]
SNU475 TICAM1
Mean 3.73
Standard deviation 0.28
Values 3.5 3.9
[62]
THLE TICAM1
Mean 8.64
Standard deviation 1.3
Values 7.7 9.5
[63]
liver TICAM1
Mean 4.77
Standard deviation 3.4
Values 7.9 1.4 7.4 2.3
[64]
ref_hepatocyte TRAF3
Mean 1.27
Standard deviation 0.83
Values 0.98 2.5 1.7 0.56 0.6
[65]
HepG2 TRAF3
Mean 20.8
Standard deviation 3.9
Values 24 18
[66]
HepG2.C3A TRAF3
Mean 12.4
Standard deviation 0.058
Values 12 12
[67]
HuH.7 TRAF3
Mean 9.05
Standard deviation 1.3
Values 10 8.7 7.9
[68]
SNU475 TRAF3
Mean 16.6
Standard deviation 0.54
Values 17 16
[69]
THLE TRAF3
Mean 24.7
Standard deviation 3.8
Values 22 27
[70]
liver TRAF3
Mean 6.87
Standard deviation 4
Values 4.4 9.3 2.6 11
[71]
ref_hepatocyte TLR3
Mean 1.04
Standard deviation 0.74
Values 0 2 0.89 0.97 1.3
[72]
HepG2 TLR3
Mean 0.16
Standard deviation 0.0012
Values 0.16 0.16
[73]
HepG2.C3A TLR3
Mean 0.103
Standard deviation 0.036
Values 0.078 0.13
[74]
HuH.7 TLR3
Mean 0.0792
Standard deviation 0.093
Values 0.033 0.19 0.019
[75]
SNU475 TLR3
Mean 1.48
Standard deviation 0.068
Values 1.5 1.4
[76]
THLE TLR3
Mean 3.51
Standard deviation 0.81
Values 4.1 2.9
[77]
liver TLR3
Mean 3.05
Standard deviation 0.49
Values 2.5 3.4 2.8 3.5
[78]
ref_hepatocyte IKBKE
Mean 0.818
Standard deviation 0.8
Values 0.91 2.2 0.36 0.25 0.39
[79]
HepG2 IKBKE
Mean 5.94
Standard deviation 0.2
Values 5.8 6.1
[80]
HepG2.C3A IKBKE
Mean 4.84
Standard deviation 0.7
Values 4.3 5.3
[81]
HuH.7 IKBKE
Mean 2.16
Standard deviation 0.28
Values 2.3 1.8 2.3
[82]
SNU475 IKBKE
Mean 8.87
Standard deviation 0.19
Values 8.7 9
[83]
THLE IKBKE
Mean 7.27
Standard deviation 2.9
Values 5.2 9.3
[84]
liver IKBKE
Mean 0.988
Standard deviation 0.21
Values 1.2 0.98 1.1 0.69