REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GNG5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 -0.88[1] -0.71[2] -1.69[3] -1.94[4] -2.21[5] -0.84[6]
2 GNB1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [7] 1.34[8] 1.35[9] 0.75[10] 1.16[11] 0.94[12] -0.49[13]
3 GNB2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [14] -0.27[15] -0.53[16] -0.32[17] -0.49[18] -0.45[19] -0.86[20]
4 GNG10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 -4.37[21] -4.09[22] -4.52[23] -3.94[24] -3.13[25] -3.60[26]
5 AAMP Angio-associated migratory cell protein [27] 0.41[28] 0.53[29] 0.40[30] -1.04[31] -1.08[32] 0.36[33]
6 GNG12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 -4.42[34] -7.36[35] 0.47[36] 1.75[37] 1.84[38] 1.23[39]
7 GNA13 Guanine nucleotide-binding protein subunit alpha-13 [40] 0.45[41] 0.61[42] 0.96[43] 1.06[44] -0.12[45] 1.28[46]
8 GNA11 Guanine nucleotide-binding protein subunit alpha-11 [47] -0.34[48] -0.43[49] -0.59[50] -1.31[51] -0.53[52] -0.51[53]
9 GNB5 Guanine nucleotide-binding protein subunit beta-5 [54] 0.43[55] 0.46[56] 1.36[57] 0.66[58] 0.77[59] 1.63[60]
10 GNAQ Guanine nucleotide-binding protein G(q) subunit alpha [61] 0.40[62] 1.17[63] 1.57[64] 1.46[65] 1.66[66] 2.18[67]
11 GNG11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 -7.85[68] -7.86[69] -7.29[70] 2.14[71] 3.44[72] 2.98[73]
12 GNG7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 1.88[74] 1.53[75] 2.21[76] -2.36[77] -1.75[78] 0.77[79]
13 GNG4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 3.80[80] 1.56[81] 5.24[82] 1.13[83] -1.00[84] -1.81[85]
14 GNB4 Guanine nucleotide-binding protein subunit beta-4 [86] -0.04[87] 0.45[88] 1.32[89] 2.55[90] 5.28[91] 4.83[92]
15 GNG2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 -5.95[93] -6.84[94] [95] 2.99[96] 2.45[97] 3.52[98]
16 TBXA2R Thromboxane A2 receptor [99] -0.97[100] -0.47[101] 0.62[102] 0.51[103] -0.05[104] 3.71[105]
17 GNA15 Guanine nucleotide-binding protein subunit alpha-15 [106] -3.05[107] -4.77[108] [109] -6.16[110] -2.61[111] 0.84[112]
18 GNA14 Guanine nucleotide-binding protein subunit alpha-14 [113] -5.73[114] -6.13[115] -5.10[116] -6.42[117] -3.34[118] 3.98[119]
19 GNGT2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [120] [121] [122] -2.19[123] -6.88[124] 0.85[125]
20 GNG3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 -0.53[126] 1.30[127] -1.05[128] -0.83[129] -1.16[130] 0.66[131]
21 GNB3 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [132] 1.92[133] 4.16[134] 3.34[135] 0.88[136] 3.58[137] -0.94[138]
22 GNGT1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 [139] [140] [141] [142] [143] [144] [145]
23 GNG8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [146] [147] [148] [149] [150] [151]
24 GNG13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [152] [153] [154] [155] [156] [157]

[1]
ref_hepatocyte GNG5
Mean 71
Standard deviation 24
Values 60 35 85 91 85
[2]
HepG2 GNG5
Mean 68.1
Standard deviation 11
Values 60 76
[3]
HepG2.C3A GNG5
Mean 68.6
Standard deviation 10
Values 61 76
[4]
HuH.7 GNG5
Mean 36.1
Standard deviation 6.8
Values 38 28 42
[5]
SNU475 GNG5
Mean 37.2
Standard deviation 3.1
Values 39 35
[6]
THLE GNG5
Mean 34.8
Standard deviation 0.49
Values 34 35
[7]
liver GNG5
Mean 33.6
Standard deviation 38
Values 75 1.4 56 1.4
[8]
ref_hepatocyte GNB1
Mean 42.7
Standard deviation 15
Values 44 60 53 31 24
[9]
HepG2 GNB1
Mean 190
Standard deviation 15
Values 2e+02 1.8e+02
[10]
HepG2.C3A GNB1
Mean 171
Standard deviation 4.5
Values 1.7e+02 1.7e+02
[11]
HuH.7 GNB1
Mean 118
Standard deviation 23
Values 1.4e+02 93 1.2e+02
[12]
SNU475 GNB1
Mean 191
Standard deviation 19
Values 2e+02 1.8e+02
[13]
THLE GNB1
Mean 185
Standard deviation 12
Values 1.8e+02 1.9e+02
[14]
liver GNB1
Mean 25.7
Standard deviation 5
Values 31 25 19 27
[15]
ref_hepatocyte GNB2
Mean 38.8
Standard deviation 20
Values 15 25 41 67 46
[16]
HepG2 GNB2
Mean 56.5
Standard deviation 6.2
Values 61 52
[17]
HepG2.C3A GNB2
Mean 42.3
Standard deviation 7.9
Values 48 37
[18]
HuH.7 GNB2
Mean 51.2
Standard deviation 3.5
Values 50 49 55
[19]
SNU475 GNB2
Mean 55.4
Standard deviation 5.7
Values 59 51
[20]
THLE GNB2
Mean 64.6
Standard deviation 5.2
Values 61 68
[21]
liver GNB2
Mean 18.2
Standard deviation 7.1
Values 24 11 25 13
[22]
ref_hepatocyte GNG10
Mean 36.1
Standard deviation 25
Values 54 68 12 12 34
[23]
HepG2 GNG10
Mean 3.07
Standard deviation 0.45
Values 2.8 3.4
[24]
HepG2.C3A GNG10
Mean 3.33
Standard deviation 1.3
Values 2.4 4.3
[25]
HuH.7 GNG10
Mean 2.59
Standard deviation 0.11
Values 2.6 2.5 2.7
[26]
SNU475 GNG10
Mean 4.73
Standard deviation 1.4
Values 5.8 3.7
[27]
THLE GNG10
Mean 9.34
Standard deviation 0.66
Values 8.9 9.8
[28]
liver GNG10
Mean 2.53
Standard deviation 1.2
Values 3.6 2.1 3.3 1.1
[29]
ref_hepatocyte AAMP
Mean 31.6
Standard deviation 8.5
Values 19 26 37 37 39
[30]
HepG2 AAMP
Mean 74.1
Standard deviation 12
Values 82 66
[31]
HepG2.C3A AAMP
Mean 71.9
Standard deviation 5.7
Values 76 68
[32]
HuH.7 AAMP
Mean 68.6
Standard deviation 23
Values 74 44 88
[33]
SNU475 AAMP
Mean 30.9
Standard deviation 0.7
Values 31 30
[34]
THLE AAMP
Mean 33.9
Standard deviation 6
Values 30 38
[35]
liver AAMP
Mean 34.6
Standard deviation 19
Values 50 19 51 18
[36]
ref_hepatocyte GNG12
Mean 16.5
Standard deviation 18
Values 0.58 46 23 5.6 7.3
[37]
HepG2 GNG12
Mean 1.35
Standard deviation 0.72
Values 1.9 0.84
[38]
HepG2.C3A GNG12
Mean 0.158
Standard deviation 0.011
Values 0.17 0.15
[39]
HuH.7 GNG12
Mean 37.3
Standard deviation 6.6
Values 44 36 31
[40]
SNU475 GNG12
Mean 111
Standard deviation 32
Values 1.3e+02 89
[41]
THLE GNG12
Mean 133
Standard deviation 28
Values 1.1e+02 1.5e+02
[42]
liver GNG12
Mean 32.7
Standard deviation 9.9
Values 36 32 43 19
[43]
ref_hepatocyte GNA13
Mean 12
Standard deviation 12
Values 13 31 12 1.9 2.2
[44]
HepG2 GNA13
Mean 28.8
Standard deviation 4
Values 26 32
[45]
HepG2.C3A GNA13
Mean 28.9
Standard deviation 0.08
Values 29 29
[46]
HuH.7 GNA13
Mean 38.4
Standard deviation 14
Values 37 53 25
[47]
SNU475 GNA13
Mean 50.3
Standard deviation 7
Values 55 45
[48]
THLE GNA13
Mean 25.1
Standard deviation 0.96
Values 24 26
[49]
liver GNA13
Mean 24.8
Standard deviation 4.4
Values 22 30 20 26
[50]
ref_hepatocyte GNA11
Mean 10
Standard deviation 6.7
Values 19 12 12 3.8 2.8
[51]
HepG2 GNA11
Mean 14
Standard deviation 0.12
Values 14 14
[52]
HepG2.C3A GNA11
Mean 11.8
Standard deviation 0.77
Values 11 12
[53]
HuH.7 GNA11
Mean 10.9
Standard deviation 2.1
Values 13 11 8.6
[54]
SNU475 GNA11
Mean 8.12
Standard deviation 0.83
Values 8.7 7.5
[55]
THLE GNA11
Mean 15.8
Standard deviation 3.1
Values 14 18
[56]
liver GNA11
Mean 5.97
Standard deviation 1.7
Values 6.1 7 3.6 7.3
[57]
ref_hepatocyte GNB5
Mean 4.79
Standard deviation 2.5
Values 6.3 6.9 2 6.5 2.2
[58]
HepG2 GNB5
Mean 11.3
Standard deviation 2.9
Values 13 9.2
[59]
HepG2.C3A GNB5
Mean 10.4
Standard deviation 1.2
Values 11 9.5
[60]
HuH.7 GNB5
Mean 20.1
Standard deviation 2.5
Values 20 23 18
[61]
SNU475 GNB5
Mean 15.2
Standard deviation 0.29
Values 15 15
[62]
THLE GNB5
Mean 18.5
Standard deviation 0.68
Values 18 19
[63]
liver GNB5
Mean 12.6
Standard deviation 4.4
Values 13 12 18 7.3
[64]
ref_hepatocyte GNAQ
Mean 1.88
Standard deviation 1
Values 1.6 2 3.6 1.1 1.1
[65]
HepG2 GNAQ
Mean 4.36
Standard deviation 1.2
Values 3.5 5.2
[66]
HepG2.C3A GNAQ
Mean 6.67
Standard deviation 0.93
Values 6 7.3
[67]
HuH.7 GNAQ
Mean 9.12
Standard deviation 3.7
Values 11 11 4.8
[68]
SNU475 GNAQ
Mean 10.4
Standard deviation 1.4
Values 11 9.4
[69]
THLE GNAQ
Mean 13.5
Standard deviation 3.4
Values 11 16
[70]
liver GNAQ
Mean 7.23
Standard deviation 3.8
Values 5.1 11 3 9.6
[71]
ref_hepatocyte GNG11
Mean 1.51
Standard deviation 1.6
Values 0 0 1.3 3.2 3
[72]
HepG2 GNG11
Mean 0.0115
Standard deviation 0.016
Values 0.023 0
[73]
HepG2.C3A GNG11
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[74]
HuH.7 GNG11
Mean 0.0158
Standard deviation 0.022
Values 0.041 0.0064 0
[75]
SNU475 GNG11
Mean 13.3
Standard deviation 2
Values 12 15
[76]
THLE GNG11
Mean 37.1
Standard deviation 6.4
Values 33 42
[77]
liver GNG11
Mean 10.1
Standard deviation 8.8
Values 16 3.1 19 2
[78]
ref_hepatocyte GNG7
Mean 0.972
Standard deviation 0.89
Values 2.2 0.22 0.098 0.76 1.6
[79]
HepG2 GNG7
Mean 6.31
Standard deviation 1.2
Values 7.2 5.5
[80]
HepG2.C3A GNG7
Mean 4.41
Standard deviation 1.7
Values 5.6 3.2
[81]
HuH.7 GNG7
Mean 7.39
Standard deviation 1.1
Values 8.1 6.1 7.9
[82]
SNU475 GNG7
Mean 0.379
Standard deviation 0.19
Values 0.51 0.24
[83]
THLE GNG7
Mean 0.654
Standard deviation 0.35
Values 0.9 0.41
[84]
liver GNG7
Mean 1.4
Standard deviation 0.99
Values 2.8 0.53 1.3 1
[85]
ref_hepatocyte GNG4
Mean 0.665
Standard deviation 1.2
Values 2.8 0.17 0.098 0.15 0.11
[86]
HepG2 GNG4
Mean 16.3
Standard deviation 4.5
Values 19 13
[87]
HepG2.C3A GNG4
Mean 3.08
Standard deviation 0.29
Values 2.9 3.3
[88]
HuH.7 GNG4
Mean 41.2
Standard deviation 8.1
Values 48 32 43
[89]
SNU475 GNG4
Mean 2.92
Standard deviation 0.47
Values 3.3 2.6
[90]
THLE GNG4
Mean 0.755
Standard deviation 0.19
Values 0.89 0.62
[91]
liver GNG4
Mean 0.161
Standard deviation 0.098
Values 0.024 0.26 0.18 0.19
[92]
ref_hepatocyte GNB4
Mean 0.389
Standard deviation 0.25
Values 0.16 0.31 0.7 0.17 0.61
[93]
HepG2 GNB4
Mean 0.666
Standard deviation 0.063
Values 0.71 0.62
[94]
HepG2.C3A GNB4
Mean 0.835
Standard deviation 0.043
Values 0.87 0.8
[95]
HuH.7 GNB4
Mean 1.6
Standard deviation 0.14
Values 1.6 1.7 1.5
[96]
SNU475 GNB4
Mean 4.59
Standard deviation 0.038
Values 4.6 4.6
[97]
THLE GNB4
Mean 34.3
Standard deviation 7.5
Values 29 40
[98]
liver GNB4
Mean 9.42
Standard deviation 4.4
Values 4.9 15 7 11
[99]
ref_hepatocyte GNG2
Mean 0.352
Standard deviation 0.41
Values 0 0.06 0.53 0.18 0.99
[100]
HepG2 GNG2
Mean 0.01
Standard deviation 0.002
Values 0.011 0.0086
[101]
HepG2.C3A GNG2
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[102]
HuH.7 GNG2
Mean 0
Standard deviation 0
Values 0 0 0
[103]
SNU475 GNG2
Mean 5.62
Standard deviation 1.4
Values 4.6 6.6
[104]
THLE GNG2
Mean 4.37
Standard deviation 0.87
Values 5 3.8
[105]
liver GNG2
Mean 3.44
Standard deviation 0.91
Values 3.5 3.6 4.4 2.2
[106]
ref_hepatocyte TBXA2R
Mean 0.317
Standard deviation 0.28
Values 0.052 0.12 0.46 0.22 0.73
[107]
HepG2 TBXA2R
Mean 0.284
Standard deviation 0.12
Values 0.37 0.2
[108]
HepG2.C3A TBXA2R
Mean 0.36
Standard deviation 0.054
Values 0.4 0.32
[109]
HuH.7 TBXA2R
Mean 0.8
Standard deviation 0.04
Values 0.84 0.76 0.81
[110]
SNU475 TBXA2R
Mean 0.905
Standard deviation 0.032
Values 0.93 0.88
[111]
THLE TBXA2R
Mean 0.694
Standard deviation 0.011
Values 0.69 0.7
[112]
liver TBXA2R
Mean 3.52
Standard deviation 1.7
Values 5.4 1.4 4.1 3.2
[113]
ref_hepatocyte GNA15
Mean 0.271
Standard deviation 0.31
Values 0 0 0.27 0.33 0.76
[114]
HepG2 GNA15
Mean 0.0573
Standard deviation 0.081
Values 0.11 0
[115]
HepG2.C3A GNA15
Mean 0.0156
Standard deviation 0.0083
Values 0.0097 0.021
[116]
HuH.7 GNA15
Mean 0
Standard deviation 0
Values 0 0 0
[117]
SNU475 GNA15
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[118]
THLE GNA15
Mean 0.101
Standard deviation 0.0083
Values 0.095 0.11
[119]
liver GNA15
Mean 0.411
Standard deviation 0.3
Values 0.047 0.6 0.28 0.71
[120]
ref_hepatocyte GNA14
Mean 0.216
Standard deviation 0.25
Values 0 0.19 0 0.28 0.61
[121]
HepG2 GNA14
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[122]
HepG2.C3A GNA14
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[123]
HuH.7 GNA14
Mean 0.0103
Standard deviation 0.013
Values 0.025 0.0064 0
[124]
SNU475 GNA14
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[125]
THLE GNA14
Mean 0.0485
Standard deviation 0.023
Values 0.065 0.032
[126]
liver GNA14
Mean 2.89
Standard deviation 0.64
Values 3.5 2.1 3.3 2.7
[127]
ref_hepatocyte GNGT2
Mean 0.154
Standard deviation 0.23
Values 0 0 0.06 0.16 0.54
[128]
HepG2 GNGT2
Mean 0
Standard deviation 0
Values 0 0
[129]
HepG2.C3A GNGT2
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 GNGT2
Mean 0
Standard deviation 0
Values 0 0 0
[131]
SNU475 GNGT2
Mean 0.0673
Standard deviation 0.062
Values 0.023 0.11
[132]
THLE GNGT2
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[133]
liver GNGT2
Mean 0.235
Standard deviation 0.19
Values 0.35 0.086 0.44 0.066
[134]
ref_hepatocyte GNG3
Mean 0.127
Standard deviation 0.2
Values 0 0 0 0.46 0.18
[135]
HepG2 GNG3
Mean 0.155
Standard deviation 0.032
Values 0.18 0.13
[136]
HepG2.C3A GNG3
Mean 0.493
Standard deviation 0.33
Values 0.73 0.26
[137]
HuH.7 GNG3
Mean 0.101
Standard deviation 0.06
Values 0.033 0.15 0.12
[138]
SNU475 GNG3
Mean 0.144
Standard deviation 0.053
Values 0.18 0.11
[139]
THLE GNG3
Mean 0.13
Standard deviation 0.018
Values 0.14 0.12
[140]
liver GNG3
Mean 0.17
Standard deviation 0.089
Values 0.047 0.26 0.21 0.17
[141]
ref_hepatocyte GNB3
Mean 0.0571
Standard deviation 0.11
Values 0.24 0 0 0 0.041
[142]
HepG2 GNB3
Mean 0.379
Standard deviation 0.11
Values 0.3 0.45
[143]
HepG2.C3A GNB3
Mean 1.61
Standard deviation 0.27
Values 1.4 1.8
[144]
HuH.7 GNB3
Mean 0.95
Standard deviation 0.47
Values 0.98 0.47 1.4
[145]
SNU475 GNB3
Mean 0.211
Standard deviation 0.003
Values 0.21 0.21
[146]
THLE GNB3
Mean 1.55
Standard deviation 0.56
Values 1.9 1.1
[147]
liver GNB3
Mean 0.0253
Standard deviation 0.019
Values 0.047 0.029 0.026 0
[148]
ref_hepatocyte GNGT1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[149]
HepG2 GNGT1
Mean 0
Standard deviation 0
Values 0 0
[150]
HepG2.C3A GNGT1
Mean 0
Standard deviation 0
Values 0 0
[151]
HuH.7 GNGT1
Mean 0.0409
Standard deviation 0.035
Values 0.0082 0.077 0.037
[152]
SNU475 GNGT1
Mean 0.0679
Standard deviation 0.0043
Values 0.065 0.071
[153]
THLE GNGT1
Mean 0
Standard deviation 0
Values 0 0
[154]
liver GNGT1
Mean 0
Standard deviation 0
Values 0 0 0 0
[155]
ref_hepatocyte GNG8
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[156]
HepG2 GNG8
Mean 0
Standard deviation 0
Values 0 0
[157]
HepG2.C3A GNG8
Mean 0
Standard deviation 0
Values 0 0
[158]
HuH.7 GNG8
Mean 0
Standard deviation 0
Values 0 0 0
[159]
SNU475 GNG8
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[160]
THLE GNG8
Mean 0
Standard deviation 0
Values 0 0
[161]
liver GNG8
Mean 0
Standard deviation 0
Values 0 0 0 0
[162]
ref_hepatocyte GNG13
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[163]
HepG2 GNG13
Mean 0
Standard deviation 0
Values 0 0
[164]
HepG2.C3A GNG13
Mean 0
Standard deviation 0
Values 0 0
[165]
HuH.7 GNG13
Mean 0.0152
Standard deviation 0.017
Values 0.033 0.013 0
[166]
SNU475 GNG13
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[167]
THLE GNG13
Mean 0.0142
Standard deviation 0.005
Values 0.018 0.011
[168]
liver GNG13
Mean 0
Standard deviation 0
Values 0 0 0 0