REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_P | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | F2 | Prothrombin | [1] | -1.41[2] | -1.04[3] | -0.76[4] | -9.68[5] | -9.93[6] | 0.25[7] |
2 | GNG5 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | -0.36[8] | -0.30[9] | -1.27[10] | -0.93[11] | -1.10[12] | -1.66[13] | |
3 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | [14] | 1.86[15] | 1.75[16] | 1.17[17] | 2.16[18] | 2.05[19] | -1.31[20] |
4 | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | [21] | 0.24[22] | -0.13[23] | 0.10[24] | 0.51[25] | 0.66[26] | -1.68[27] |
5 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | -3.86[28] | -3.69[29] | -4.10[30] | -2.93[31] | -2.02[32] | -4.42[33] | |
6 | GNG12 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 | -3.91[34] | -6.96[35] | 0.89[36] | 2.76[37] | 2.95[38] | 0.41[39] | |
7 | GNA13 | Guanine nucleotide-binding protein subunit alpha-13 | [40] | 0.96[41] | 1.01[42] | 1.38[43] | 2.07[44] | 0.99[45] | 0.46[46] |
8 | MAPK1 | Mitogen-activated protein kinase 1 | [47] | 2.55[48] | 2.57[49] | 2.30[50] | 2.73[51] | 2.47[52] | 1.70[53] |
9 | GNA11 | Guanine nucleotide-binding protein subunit alpha-11 | [54] | 0.18[55] | -0.02[56] | -0.17[57] | -0.31[58] | 0.58[59] | -1.33[60] |
10 | ARRB2 | Beta-arrestin-2 | [61] | 1.01[62] | 1.28[63] | 1.13[64] | -0.44[65] | 0.46[66] | -0.95[67] |
11 | GNB5 | Guanine nucleotide-binding protein subunit beta-5 | [68] | 0.94[69] | 0.86[70] | 1.78[71] | 1.67[72] | 1.88[73] | 0.81[74] |
12 | GNA12 | Guanine nucleotide-binding protein subunit alpha-12 | [75] | 2.83[76] | 2.63[77] | 1.84[78] | 2.61[79] | 2.79[80] | 0.01[81] |
13 | MAPK3 | Mitogen-activated protein kinase 3 | [82] | 2.70[83] | 2.62[84] | 2.56[85] | 1.30[86] | 1.41[87] | -1.12[88] |
14 | SRC | Proto-oncogene tyrosine-protein kinase Src | [89] | 3.87[90] | 3.73[91] | 2.63[92] | 3.28[93] | 2.55[94] | -0.93[95] |
15 | GNAQ | Guanine nucleotide-binding protein G(q) subunit alpha | [96] | 0.92[97] | 1.58[98] | 1.99[99] | 2.46[100] | 2.78[101] | 1.36[102] |
16 | GNG11 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 | -7.33[103] | -7.45[104] | -6.87[105] | 3.14[106] | 4.55[107] | 2.16[108] | |
17 | F2R | Proteinase-activated receptor 1 | [109] | 3.69[110] | 2.05[111] | 2.50[112] | 4.72[113] | 4.23[114] | 2.66[115] |
18 | GNG7 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 | 2.40[116] | 1.93[117] | 2.63[118] | -1.36[119] | -0.64[120] | -0.05[121] | |
19 | F2RL2 | Proteinase-activated receptor 3 | [122] | -4.59[123] | -3.75[124] | -1.92[125] | 4.59[126] | -0.39[127] | 0.75[128] |
20 | GNG4 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 | 4.32[129] | 1.96[130] | 5.66[131] | 2.13[132] | 0.11[133] | -2.63[134] | |
21 | ARRB1 | Beta-arrestin-1 | [135] | 4.43[136] | 4.11[137] | 3.31[138] | 3.03[139] | 2.93[140] | 3.19[141] |
22 | GNB4 | Guanine nucleotide-binding protein subunit beta-4 | [142] | 0.48[143] | 0.85[144] | 1.75[145] | 3.56[146] | 6.39[147] | 4.01[148] |
23 | GNG2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | -5.43[149] | -6.43[150] | [151] | 3.99[152] | 3.56[153] | 2.70[154] | |
24 | GNA15 | Guanine nucleotide-binding protein subunit alpha-15 | [155] | -2.54[156] | -4.37[157] | [158] | -5.15[159] | -1.50[160] | 0.02[161] |
25 | GNA14 | Guanine nucleotide-binding protein subunit alpha-14 | [162] | -5.21[163] | -5.73[164] | -4.68[165] | -5.41[166] | -2.23[167] | 3.16[168] |
26 | F2RL3 | Proteinase-activated receptor 4 | [169] | -2.56[170] | -1.55[171] | -2.49[172] | -2.55[173] | 1.34[174] | -0.43[175] |
27 | GNGT2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 | [176] | [177] | [178] | -1.19[179] | -5.77[180] | 0.03[181] | |
28 | GNG3 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 | -0.01[182] | 1.70[183] | -0.63[184] | 0.18[185] | -0.04[186] | -0.16[187] | |
29 | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 | [188] | 2.43[189] | 4.57[190] | 3.76[191] | 1.88[192] | 4.69[193] | -1.76[194] |
30 | GNG13 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 | [195] | [196] | [197] | [198] | [199] | [200] | |
31 | GNG8 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 | [201] | [202] | [203] | [204] | [205] | [206] | |
32 | GNGT1 | Guanine nucleotide-binding protein G(T) subunit gamma-T1 | [207] | [208] | [209] | [210] | [211] | [212] | [213] |