REACTOME_TFAP2_AP_2_FAMILY_REGULATES_TRANSCRIPTION_OF_GROWTH_FACTORS_AND_THEIR_RECEPTORS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 VEGFA Vascular endothelial growth factor A [1] 0.10[2] 0.56[3] -0.41[4] -0.67[5] 0.04[6] -0.24[7]
2 YY1 Transcriptional repressor protein YY1 [8] -1.10[9] -1.97[10] -1.65[11] -0.41[12] -0.87[13] -1.00[14]
3 ERBB2 Receptor tyrosine-protein kinase erbB-2 [15] 1.26[16] -0.81[17] 0.80[18] 0.15[19] -0.25[20] -0.86[21]
4 EGFR Epidermal growth factor receptor [22] -1.81[23] -3.07[24] 0.24[25] -0.67[26] -0.06[27] 1.63[28]
5 ATAD2 ATPase family AAA domain-containing protein 2 [29] 0.53[30] 1.85[31] 1.88[32] 1.83[33] 1.74[34] -0.38[35]
6 TGFA Protransforming growth factor alpha [36] 0.68[37] 0.86[38] -9.76[39] -2.07[40] -3.29[41] -1.41[42]
7 ESR1 Estrogen receptor [43] -8.42[44] [45] -7.35[46] -5.27[47] -7.54[48] 1.38[49]
8 KIT Mast/stem cell growth factor receptor Kit [50] -4.10[51] -6.87[52] [53] 1.40[54] -4.14[55] 2.62[56]
9 CGA Glycoprotein hormones alpha chain [57] [58] [59] -3.92[60] -4.62[61] -5.94[62] -5.12[63]
10 TFAP2C Transcription factor AP-2 gamma [64] [65] [66] [67] 2.92[68] 3.65[69] 0.03[70]
11 TFAP2A Transcription factor AP-2-alpha [71] [72] [73] [74] [75] [76] [77]
12 CGB8 [78] [79] [80] [81] [82] [83] [84]
13 TFAP2B Transcription factor AP-2-beta [85] [86] [87] [88] [89] [90] [91]
14 CGB3 Choriogonadotropin subunit beta 3 [92] [93] [94] [95] [96] [97] [98]
15 CGB5 [99] [100] [101] [102] [103] [104] [105]
[1]
ref_hepatocyte VEGFA
Mean 15.4
Standard deviation 8.3
Values 12 5.2 12 22 25
[2]
HepG2 VEGFA
Mean 78.9
Standard deviation 39
Values 1.1e+02 51
[3]
HepG2.C3A VEGFA
Mean 178
Standard deviation 91
Values 2.4e+02 1.1e+02
[4]
HuH.7 VEGFA
Mean 64.6
Standard deviation 7.4
Values 59 62 73
[5]
SNU475 VEGFA
Mean 38.2
Standard deviation 17
Values 26 50
[6]
THLE VEGFA
Mean 70.1
Standard deviation 17
Values 82 58
[7]
liver VEGFA
Mean 37.5
Standard deviation 27
Values 18 70 14 48
[8]
ref_hepatocyte YY1
Mean 14
Standard deviation 2.1
Values 15 16 15 11 14
[9]
HepG2 YY1
Mean 31.4
Standard deviation 3.8
Values 29 34
[10]
HepG2.C3A YY1
Mean 28.1
Standard deviation 3.2
Values 26 30
[11]
HuH.7 YY1
Mean 25.1
Standard deviation 3.8
Values 27 28 21
[12]
SNU475 YY1
Mean 41.9
Standard deviation 1.7
Values 43 41
[13]
THLE YY1
Mean 34.2
Standard deviation 6.5
Values 30 39
[14]
liver YY1
Mean 20.2
Standard deviation 4.1
Values 24 22 15 20
[15]
ref_hepatocyte ERBB2
Mean 6.44
Standard deviation 3.8
Values 13 3.9 4.7 3.7 7.1
[16]
HepG2 ERBB2
Mean 73.6
Standard deviation 10
Values 66 81
[17]
HepG2.C3A ERBB2
Mean 29
Standard deviation 6.9
Values 34 24
[18]
HuH.7 ERBB2
Mean 62.5
Standard deviation 7.1
Values 69 55 63
[19]
SNU475 ERBB2
Mean 28.2
Standard deviation 8.4
Values 34 22
[20]
THLE ERBB2
Mean 24.1
Standard deviation 2.7
Values 22 26
[21]
liver ERBB2
Mean 10.2
Standard deviation 3.4
Values 7.9 8.1 9.6 15
[22]
ref_hepatocyte EGFR
Mean 5.53
Standard deviation 4.2
Values 0.94 8.5 11 3.5 3.5
[23]
HepG2 EGFR
Mean 7.53
Standard deviation 0.89
Values 6.9 8.2
[24]
HepG2.C3A EGFR
Mean 5.18
Standard deviation 0.67
Values 5.7 4.7
[25]
HuH.7 EGFR
Mean 36.6
Standard deviation 25
Values 32 63 15
[26]
SNU475 EGFR
Mean 13.7
Standard deviation 0.74
Values 13 14
[27]
THLE EGFR
Mean 23.6
Standard deviation 4.4
Values 20 27
[28]
liver EGFR
Mean 49.4
Standard deviation 14
Values 39 69 47 42
[29]
ref_hepatocyte ATAD2
Mean 4.19
Standard deviation 4.2
Values 10 7.1 0.27 1.4 2
[30]
HepG2 ATAD2
Mean 28.9
Standard deviation 19
Values 16 42
[31]
HepG2.C3A ATAD2
Mean 119
Standard deviation 50
Values 84 1.5e+02
[32]
HuH.7 ATAD2
Mean 86.3
Standard deviation 21
Values 1.1e+02 67 84
[33]
SNU475 ATAD2
Mean 58.6
Standard deviation 13
Values 49 68
[34]
THLE ATAD2
Mean 61.8
Standard deviation 4.6
Values 65 59
[35]
liver ATAD2
Mean 9.23
Standard deviation 2.4
Values 11 12 7.7 6.7
[36]
ref_hepatocyte TGFA
Mean 2
Standard deviation 1.3
Values 3.8 2.7 2.1 0.72 0.76
[37]
HepG2 TGFA
Mean 15.3
Standard deviation 2.1
Values 17 14
[38]
HepG2.C3A TGFA
Mean 28.4
Standard deviation 4.2
Values 25 31
[39]
HuH.7 TGFA
Mean 0.0129
Standard deviation 0.0035
Values 0.016 0.013 0.0094
[40]
SNU475 TGFA
Mean 1.88
Standard deviation 0.53
Values 1.5 2.3
[41]
THLE TGFA
Mean 0.903
Standard deviation 0.47
Values 1.2 0.57
[42]
liver TGFA
Mean 2.16
Standard deviation 0.15
Values 2.1 2.3 2.2 2
[43]
ref_hepatocyte ESR1
Mean 1.54
Standard deviation 2.3
Values 0 0.17 0 2.2 5.3
[44]
HepG2 ESR1
Mean 0.0215
Standard deviation 0.018
Values 0.034 0.0086
[45]
HepG2.C3A ESR1
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 ESR1
Mean 0.0525
Standard deviation 0.047
Values 0.11 0.032 0.019
[47]
SNU475 ESR1
Mean 0.157
Standard deviation 0.14
Values 0.06 0.25
[48]
THLE ESR1
Mean 0.0367
Standard deviation 0.0067
Values 0.041 0.032
[49]
liver ESR1
Mean 11.5
Standard deviation 7
Values 7.2 11 6.1 22
[50]
ref_hepatocyte KIT
Mean 0.0798
Standard deviation 0.075
Values 0 0 0.15 0.1 0.15
[51]
HepG2 KIT
Mean 0.0222
Standard deviation 0.025
Values 0.04 0.0043
[52]
HepG2.C3A KIT
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[53]
HuH.7 KIT
Mean 0
Standard deviation 0
Values 0 0 0
[54]
SNU475 KIT
Mean 0.83
Standard deviation 0.64
Values 1.3 0.38
[55]
THLE KIT
Mean 0.0201
Standard deviation 0.013
Values 0.03 0.011
[56]
liver KIT
Mean 1.41
Standard deviation 1.3
Values 0.21 3 1.9 0.54
[57]
ref_hepatocyte CGA
Mean 0.0776
Standard deviation 0.17
Values 0 0 0 0.39 0
[58]
HepG2 CGA
Mean 0
Standard deviation 0
Values 0 0
[59]
HepG2.C3A CGA
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 CGA
Mean 0.0287
Standard deviation 0.011
Values 0.016 0.032 0.037
[61]
SNU475 CGA
Mean 0.0125
Standard deviation 0.011
Values 0.0046 0.02
[62]
THLE CGA
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[63]
liver CGA
Mean 0.00642
Standard deviation 0.013
Values 0 0 0.026 0
[64]
ref_hepatocyte TFAP2C
Mean 0.0185
Standard deviation 0.041
Values 0 0 0.092 0 0
[65]
HepG2 TFAP2C
Mean 0
Standard deviation 0
Values 0 0
[66]
HepG2.C3A TFAP2C
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 TFAP2C
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 TFAP2C
Mean 0.552
Standard deviation 0.6
Values 0.13 0.98
[69]
THLE TFAP2C
Mean 1.03
Standard deviation 0.31
Values 1.2 0.81
[70]
liver TFAP2C
Mean 0.0543
Standard deviation 0.05
Values 0 0.086 0.026 0.11
[71]
ref_hepatocyte TFAP2A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[72]
HepG2 TFAP2A
Mean 0.0229
Standard deviation 0.032
Values 0.046 0
[73]
HepG2.C3A TFAP2A
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[74]
HuH.7 TFAP2A
Mean 0.224
Standard deviation 0.043
Values 0.26 0.23 0.18
[75]
SNU475 TFAP2A
Mean 10.4
Standard deviation 1.4
Values 11 9.5
[76]
THLE TFAP2A
Mean 2.69
Standard deviation 1
Values 2 3.4
[77]
liver TFAP2A
Mean 0.0326
Standard deviation 0.047
Values 0 0.014 0.1 0.013
[78]
ref_hepatocyte CGB8
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 CGB8
Mean 0
Standard deviation 0
Values 0 0
[80]
HepG2.C3A CGB8
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 CGB8
Mean 0
Standard deviation 0
Values 0 0 0
[82]
SNU475 CGB8
Mean 0.00992
Standard deviation 0.0075
Values 0.0046 0.015
[83]
THLE CGB8
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[84]
liver CGB8
Mean 0.00331
Standard deviation 0.0066
Values 0 0 0 0.013
[85]
ref_hepatocyte TFAP2B
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 TFAP2B
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A TFAP2B
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 TFAP2B
Mean 0.0935
Standard deviation 0.061
Values 0.033 0.15 0.094
[89]
SNU475 TFAP2B
Mean 0
Standard deviation 0
Values 0 0
[90]
THLE TFAP2B
Mean 0
Standard deviation 0
Values 0 0
[91]
liver TFAP2B
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[92]
ref_hepatocyte CGB3
Missing
[93]
HepG2 CGB3
Missing
[94]
HepG2.C3A CGB3
Missing
[95]
HuH.7 CGB3
Missing
[96]
SNU475 CGB3
Missing
[97]
THLE CGB3
Missing
[98]
liver CGB3
Missing
[99]
ref_hepatocyte CGB5
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[100]
HepG2 CGB5
Missing
[101]
HepG2.C3A CGB5
Missing
[102]
HuH.7 CGB5
Missing
[103]
SNU475 CGB5
Missing
[104]
THLE CGB5
Missing
[105]
liver CGB5
Missing