REACTOME_BH3_ONLY_PROTEINS_ASSOCIATE_WITH_AND_INACTIVATE_ANTI_APOPTOTIC_BCL_2_MEMBERS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 STAT3 Signal transducer and activator of transcription 3 [1] -0.47[2] -1.35[3] -1.35[4] -0.11[5] -0.08[6] 1.33[7]
2 BCL2L1 Bcl-2-like protein 1 [8] 1.12[9] 1.13[10] 1.34[11] -0.97[12] 0.18[13] -1.90[14]
3 BAD Bcl2-associated agonist of cell death [15] -2.69[16] -1.94[17] -3.63[18] -1.42[19] -0.26[20] -2.50[21]
4 BID BH3-interacting domain death agonist [22] -1.29[23] -0.56[24] -1.69[25] -0.64[26] -0.42[27] -0.91[28]
5 BBC3 Bcl-2-binding component 3 [29] -0.28[30] 0.23[31] -1.02[32] -3.16[33] -1.64[34] -5.41[35]
6 BMF Bcl-2-modifying factor [36] -0.20[37] 0.79[38] 1.11[39] 3.28[40] -1.32[41] -1.88[42]
7 PMAIP1 Phorbol-12-myristate-13-acetate-induced protein 1 [43] -0.97[44] -3.71[45] -0.91[46] 1.93[47] 1.91[48] -5.38[49]
8 BCL2L11 Bcl-2-like protein 11 [50] 0.48[51] 1.11[52] 0.70[53] 1.51[54] 1.25[55] 0.91[56]
9 BCL2 Apoptosis regulator Bcl-2 [57] -3.88[58] 2.15[59] -6.00[60] 1.42[61] 1.89[62] 2.15[63]
[1]
ref_hepatocyte STAT3
Mean 30.1
Standard deviation 11
Values 26 25 18 46 36
[2]
HepG2 STAT3
Mean 97.5
Standard deviation 10
Values 90 1e+02
[3]
HepG2.C3A STAT3
Mean 30.7
Standard deviation 5.2
Values 34 27
[4]
HuH.7 STAT3
Mean 49.1
Standard deviation 15
Values 47 65 35
[5]
SNU475 STAT3
Mean 65.4
Standard deviation 12
Values 74 57
[6]
THLE STAT3
Mean 44.3
Standard deviation 6
Values 40 49
[7]
liver STAT3
Mean 227
Standard deviation 42
Values 1.9e+02 2.3e+02 2.8e+02 2e+02
[8]
ref_hepatocyte BCL2L1
Mean 26.8
Standard deviation 12
Values 16 44 34 23 16
[9]
HepG2 BCL2L1
Mean 260
Standard deviation 56
Values 3e+02 2.2e+02
[10]
HepG2.C3A BCL2L1
Mean 152
Standard deviation 4.3
Values 1.5e+02 1.5e+02
[11]
HuH.7 BCL2L1
Mean 283
Standard deviation 60
Values 3.1e+02 2.1e+02 3.2e+02
[12]
SNU475 BCL2L1
Mean 32.1
Standard deviation 4.1
Values 29 35
[13]
THLE BCL2L1
Mean 47
Standard deviation 4.7
Values 44 50
[14]
liver BCL2L1
Mean 21.6
Standard deviation 11
Values 31 9.8 31 14
[15]
ref_hepatocyte BAD
Mean 16.7
Standard deviation 11
Values 5.4 16 6.7 28 27
[16]
HepG2 BAD
Mean 11.6
Standard deviation 0.78
Values 11 12
[17]
HepG2.C3A BAD
Mean 11.3
Standard deviation 1.1
Values 10 12
[18]
HuH.7 BAD
Mean 5.61
Standard deviation 0.7
Values 5 6.4 5.5
[19]
SNU475 BAD
Mean 14.6
Standard deviation 2.5
Values 16 13
[20]
THLE BAD
Mean 21.6
Standard deviation 1.3
Values 21 23
[21]
liver BAD
Mean 8.85
Standard deviation 6.2
Values 16 3.7 12 3.7
[22]
ref_hepatocyte BID
Mean 12.3
Standard deviation 4.8
Values 4.5 12 17 15 12
[23]
HepG2 BID
Mean 22.5
Standard deviation 0.74
Values 22 23
[24]
HepG2.C3A BID
Mean 21.5
Standard deviation 4.7
Values 18 25
[25]
HuH.7 BID
Mean 15.9
Standard deviation 4.6
Values 15 12 21
[26]
SNU475 BID
Mean 18.5
Standard deviation 1.4
Values 19 17
[27]
THLE BID
Mean 14.3
Standard deviation 1.7
Values 13 15
[28]
liver BID
Mean 19.7
Standard deviation 11
Values 30 9.4 29 10
[29]
ref_hepatocyte BBC3
Mean 4.09
Standard deviation 4.3
Values 3.6 0.92 11 3.2 1.3
[30]
HepG2 BBC3
Mean 15.1
Standard deviation 11
Values 23 7
[31]
HepG2.C3A BBC3
Mean 12.4
Standard deviation 9.8
Values 19 5.5
[32]
HuH.7 BBC3
Mean 8.39
Standard deviation 3.1
Values 5.7 12 7.8
[33]
SNU475 BBC3
Mean 1.08
Standard deviation 0.44
Values 1.4 0.77
[34]
THLE BBC3
Mean 2.04
Standard deviation 0.082
Values 2.1 2
[35]
liver BBC3
Mean 0.288
Standard deviation 0.11
Values 0.24 0.3 0.18 0.44
[36]
ref_hepatocyte BMF
Mean 2.81
Standard deviation 5.3
Values 12 0.45 0.57 0.29 0.39
[37]
HepG2 BMF
Mean 10.9
Standard deviation 5
Values 14 7.4
[38]
HepG2.C3A BMF
Mean 12.6
Standard deviation 10
Values 20 5.3
[39]
HuH.7 BMF
Mean 25.2
Standard deviation 17
Values 15 44 16
[40]
SNU475 BMF
Mean 63.9
Standard deviation 40
Values 92 36
[41]
THLE BMF
Mean 1.75
Standard deviation 0.33
Values 1.5 2
[42]
liver BMF
Mean 2.29
Standard deviation 1.9
Values 1.4 2.1 0.67 5.1
[43]
ref_hepatocyte PMAIP1
Mean 2.2
Standard deviation 2.9
Values 0.061 3.5 6.7 0.22 0.54
[44]
HepG2 PMAIP1
Mean 5.03
Standard deviation 2.9
Values 7.1 3
[45]
HepG2.C3A PMAIP1
Mean 0.435
Standard deviation 0.037
Values 0.41 0.46
[46]
HuH.7 PMAIP1
Mean 4.88
Standard deviation 0.84
Values 4.6 5.8 4.2
[47]
SNU475 PMAIP1
Mean 19.7
Standard deviation 2.1
Values 18 21
[48]
THLE PMAIP1
Mean 12.8
Standard deviation 1
Values 14 12
[49]
liver PMAIP1
Mean 0.159
Standard deviation 0.092
Values 0.21 0.11 0.26 0.053
[50]
ref_hepatocyte BCL2L11
Mean 1.6
Standard deviation 0.72
Values 2.4 0.45 1.7 2 1.5
[51]
HepG2 BCL2L11
Mean 10.1
Standard deviation 0.76
Values 11 9.5
[52]
HepG2.C3A BCL2L11
Mean 9.01
Standard deviation 0.3
Values 8.8 9.2
[53]
HuH.7 BCL2L11
Mean 10.8
Standard deviation 1
Values 11 12 9.7
[54]
SNU475 BCL2L11
Mean 10.7
Standard deviation 3
Values 13 8.6
[55]
THLE BCL2L11
Mean 5.92
Standard deviation 0.75
Values 5.4 6.4
[56]
liver BCL2L11
Mean 9.03
Standard deviation 4.2
Values 7.8 6.5 6.5 15
[57]
ref_hepatocyte BCL2
Mean 0.0984
Standard deviation 0.087
Values 0.019 0 0.15 0.12 0.2
[58]
HepG2 BCL2
Mean 0.0301
Standard deviation 0.0061
Values 0.034 0.026
[59]
HepG2.C3A BCL2
Mean 1.13
Standard deviation 0.21
Values 1.3 0.99
[60]
HuH.7 BCL2
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[61]
SNU475 BCL2
Mean 0.618
Standard deviation 0.094
Values 0.55 0.68
[62]
THLE BCL2
Mean 0.568
Standard deviation 0.0088
Values 0.56 0.57
[63]
liver BCL2
Mean 1.31
Standard deviation 1
Values 0.49 1.8 0.49 2.5