REACTOME_BETA_OXIDATION_OF_VERY_LONG_CHAIN_FATTY_ACIDS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ACAA1 3-ketoacyl-CoA thiolase, peroxisomal [1] -0.93[2] -0.05[3] -1.32[4] -1.88[5] -1.55[6] -0.48[7]
2 HSD17B4 Peroxisomal multifunctional enzyme type 2 [8] 0.09[9] -0.16[10] 0.19[11] 0.46[12] 1.16[13] 0.15[14]
3 ECI2 Enoyl-CoA delta isomerase 2, mitochondrial [15] -0.22[16] -0.08[17] -0.42[18] 0.07[19] -0.89[20] -1.59[21]
4 DECR2 Peroxisomal 2,4-dienoyl-CoA reductase [22] -0.68[23] -0.98[24] 0.69[25] -1.35[26] -1.44[27] -0.37[28]
5 EHHADH Peroxisomal bifunctional enzyme [29] -1.35[30] -1.20[31] 0.00[32] -0.78[33] -1.44[34] 1.02[35]
6 ACOX1 Peroxisomal acyl-coenzyme A oxidase 1 [36] 2.45[37] 2.27[38] 2.38[39] 2.03[40] 1.71[41] 2.46[42]
7 MLYCD Malonyl-CoA decarboxylase, mitochondrial [43] 0.03[44] -0.42[45] -0.24[46] -0.14[47] 0.16[48] 0.39[49]
8 ACOT8 Acyl-coenzyme A thioesterase 8 [50] 0.58[51] 0.44[52] 1.10[53] 1.50[54] 1.04[55] -1.48[56]
9 ACOT4 Acyl-coenzyme A thioesterase 4 [57] -7.59[58] -6.53[59] -1.60[60] 0.92[61] -1.66[62] 0.13[63]
10 ABCD1 ATP-binding cassette sub-family D member 1 [64] 4.36[65] 2.90[66] 1.37[67] 3.93[68] 3.04[69] 0.31[70]
11 ACOT6 Putative acyl-coenzyme A thioesterase 6 [71] -3.34[72] -4.18[73] -1.53[74] -5.27[75] -2.48[76] -1.22[77]
[1]
ref_hepatocyte ACAA1
Mean 118
Standard deviation 1e+02
Values 71 41 25 2.1e+02 2.5e+02
[2]
HepG2 ACAA1
Mean 47.6
Standard deviation 17
Values 35 60
[3]
HepG2.C3A ACAA1
Mean 119
Standard deviation 20
Values 1.3e+02 1.1e+02
[4]
HuH.7 ACAA1
Mean 31.3
Standard deviation 4
Values 27 32 35
[5]
SNU475 ACAA1
Mean 10.8
Standard deviation 2.1
Values 12 9.3
[6]
THLE ACAA1
Mean 14.9
Standard deviation 1.6
Values 14 16
[7]
liver ACAA1
Mean 185
Standard deviation 78
Values 2.5e+02 1.2e+02 2.5e+02 1.2e+02
[8]
ref_hepatocyte HSD17B4
Mean 85.8
Standard deviation 51
Values 1.2e+02 57 11 1.1e+02 1.3e+02
[9]
HepG2 HSD17B4
Mean 70.1
Standard deviation 24
Values 53 87
[10]
HepG2.C3A HSD17B4
Mean 80.1
Standard deviation 0.22
Values 80 80
[11]
HuH.7 HSD17B4
Mean 64.3
Standard deviation 5.5
Values 68 58 67
[12]
SNU475 HSD17B4
Mean 39.5
Standard deviation 6.9
Values 44 35
[13]
THLE HSD17B4
Mean 70.3
Standard deviation 2.4
Values 69 72
[14]
liver HSD17B4
Mean 208
Standard deviation 20
Values 1.9e+02 2.2e+02 2.3e+02 1.9e+02
[15]
ref_hepatocyte ECI2
Mean 74.3
Standard deviation 36
Values 93 54 26 76 1.2e+02
[16]
HepG2 ECI2
Mean 48.9
Standard deviation 10
Values 42 56
[17]
HepG2.C3A ECI2
Mean 73.5
Standard deviation 1.4
Values 73 75
[18]
HuH.7 ECI2
Mean 36.6
Standard deviation 7.2
Values 37 29 43
[19]
SNU475 ECI2
Mean 26.1
Standard deviation 4.3
Values 29 23
[20]
THLE ECI2
Mean 14.7
Standard deviation 0.26
Values 15 14
[21]
liver ECI2
Mean 53.9
Standard deviation 36
Values 96 22 71 27
[22]
ref_hepatocyte DECR2
Mean 35.4
Standard deviation 41
Values 6.9 9.5 3.8 62 95
[23]
HepG2 DECR2
Mean 17
Standard deviation 1.7
Values 16 18
[24]
HepG2.C3A DECR2
Mean 18.8
Standard deviation 1.7
Values 20 18
[25]
HuH.7 DECR2
Mean 37.5
Standard deviation 11
Values 38 27 48
[26]
SNU475 DECR2
Mean 4.65
Standard deviation 2.4
Values 6.3 3
[27]
THLE DECR2
Mean 4.79
Standard deviation 0.45
Values 4.5 5.1
[28]
liver DECR2
Mean 59.6
Standard deviation 51
Values 1.2e+02 15 80 22
[29]
ref_hepatocyte EHHADH
Mean 33.3
Standard deviation 41
Values 13 9 4.6 36 1e+02
[30]
HepG2 EHHADH
Mean 10
Standard deviation 5.1
Values 6.4 14
[31]
HepG2.C3A EHHADH
Mean 15.2
Standard deviation 3.7
Values 13 18
[32]
HuH.7 EHHADH
Mean 22
Standard deviation 3.4
Values 25 19 22
[33]
SNU475 EHHADH
Mean 6.51
Standard deviation 1.9
Values 7.9 5.1
[34]
THLE EHHADH
Mean 4.51
Standard deviation 0.22
Values 4.4 4.7
[35]
liver EHHADH
Mean 147
Standard deviation 40
Values 1.9e+02 1e+02 1.2e+02 1.8e+02
[36]
ref_hepatocyte ACOX1
Mean 11.2
Standard deviation 8.5
Values 15 4.5 2.3 11 23
[37]
HepG2 ACOX1
Mean 46.9
Standard deviation 9
Values 41 53
[38]
HepG2.C3A ACOX1
Mean 56.3
Standard deviation 2.2
Values 58 55
[39]
HuH.7 ACOX1
Mean 38.2
Standard deviation 5
Values 43 33 38
[40]
SNU475 ACOX1
Mean 15.2
Standard deviation 4.1
Values 18 12
[41]
THLE ACOX1
Mean 13.4
Standard deviation 1.8
Values 12 15
[42]
liver ACOX1
Mean 134
Standard deviation 77
Values 63 1.8e+02 75 2.2e+02
[43]
ref_hepatocyte MLYCD
Mean 9.36
Standard deviation 8.7
Values 2.4 2.7 3.9 19 18
[44]
HepG2 MLYCD
Mean 7.35
Standard deviation 1.3
Values 6.4 8.3
[45]
HepG2.C3A MLYCD
Mean 7.3
Standard deviation 0.37
Values 7.6 7
[46]
HuH.7 MLYCD
Mean 5.21
Standard deviation 0.55
Values 5.2 4.7 5.8
[47]
SNU475 MLYCD
Mean 2.84
Standard deviation 1
Values 3.6 2.1
[48]
THLE MLYCD
Mean 3.83
Standard deviation 0.37
Values 3.6 4.1
[49]
liver MLYCD
Mean 26.8
Standard deviation 5.4
Values 22 23 33 30
[50]
ref_hepatocyte ACOT8
Mean 9.09
Standard deviation 5.1
Values 7.6 4.2 4.6 14 15
[51]
HepG2 ACOT8
Mean 10.5
Standard deviation 0.047
Values 10 10
[52]
HepG2.C3A ACOT8
Mean 12.9
Standard deviation 0.35
Values 13 13
[53]
HuH.7 ACOT8
Mean 12.8
Standard deviation 3.6
Values 14 8.8 16
[54]
SNU475 ACOT8
Mean 8.62
Standard deviation 1.7
Values 9.8 7.4
[55]
THLE ACOT8
Mean 6.83
Standard deviation 0.25
Values 6.7 7
[56]
liver ACOT8
Mean 7.1
Standard deviation 3.2
Values 9.8 5.3 9.8 3.5
[57]
ref_hepatocyte ACOT4
Mean 3.95
Standard deviation 3.9
Values 0 1.7 1.8 8.2 8
[58]
HepG2 ACOT4
Mean 0.0158
Standard deviation 0.01
Values 0.023 0.0086
[59]
HepG2.C3A ACOT4
Mean 0.0447
Standard deviation 0.033
Values 0.068 0.021
[60]
HuH.7 ACOT4
Mean 0.861
Standard deviation 0.3
Values 0.86 0.56 1.2
[61]
SNU475 ACOT4
Mean 2.5
Standard deviation 0.18
Values 2.6 2.4
[62]
THLE ACOT4
Mean 0.457
Standard deviation 0.053
Values 0.42 0.49
[63]
liver ACOT4
Mean 9.44
Standard deviation 3.9
Values 14 6 12 6.2
[64]
ref_hepatocyte ABCD1
Mean 2.32
Standard deviation 1.2
Values 4.2 1.1 2.6 2.4 1.3
[65]
HepG2 ABCD1
Mean 36.5
Standard deviation 6.2
Values 41 32
[66]
HepG2.C3A ABCD1
Mean 18.2
Standard deviation 4.3
Values 21 15
[67]
HuH.7 ABCD1
Mean 3.94
Standard deviation 0.8
Values 3.7 4.8 3.3
[68]
SNU475 ABCD1
Mean 11.8
Standard deviation 4.2
Values 15 8.8
[69]
THLE ABCD1
Mean 6.97
Standard deviation 0.6
Values 6.5 7.4
[70]
liver ABCD1
Mean 6.26
Standard deviation 1.8
Values 5.9 7.6 3.9 7.6
[71]
ref_hepatocyte ACOT6
Mean 0.802
Standard deviation 1
Values 0 0 0.42 2.4 1.1
[72]
HepG2 ACOT6
Mean 0.0608
Standard deviation 0.005
Values 0.057 0.064
[73]
HepG2.C3A ACOT6
Mean 0.0463
Standard deviation 0.01
Values 0.039 0.054
[74]
HuH.7 ACOT6
Mean 0.183
Standard deviation 0.12
Values 0.16 0.077 0.31
[75]
SNU475 ACOT6
Mean 0.00696
Standard deviation 0.0098
Values 0.014 0
[76]
THLE ACOT6
Mean 0.0527
Standard deviation 0.059
Values 0.095 0.011
[77]
liver ACOT6
Mean 0.751
Standard deviation 0.27
Values 1.1 0.56 0.9 0.49