REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | SAA1 | Serum amyloid A-1 protein | [1] | -14.08[2] | -14.15[3] | -9.48[4] | -12.31[5] | -3.77[6] | -0.15[7] |
2 | UBB | Polyubiquitin-B | [8] | 2.86[9] | 2.64[10] | 2.70[11] | 2.47[12] | 2.63[13] | 0.81[14] |
3 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [15] | [16] | [17] | [18] | [19] | [20] | [21] |
4 | UBC | Polyubiquitin-C | [22] | 3.31[23] | 3.40[24] | 3.07[25] | 3.32[26] | 3.01[27] | 1.26[28] |
5 | HMGB1 | High mobility group protein B1 | [29] | 4.76[30] | 5.48[31] | 5.13[32] | 5.71[33] | 4.89[34] | 2.13[35] |
6 | NFKBIA | NF-kappa-B inhibitor alpha | [36] | 4.01[37] | 2.19[38] | 1.73[39] | 1.73[40] | 3.32[41] | 1.55[42] |
7 | APP | Amyloid-beta A4 protein | [43] | 5.44[44] | 4.87[45] | 5.44[46] | 6.03[47] | 6.14[48] | 2.82[49] |
8 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [50] | 5.74[51] | 5.63[52] | 6.58[53] | 4.72[54] | 5.24[55] | 2.03[56] |
9 | UBE2V1 | Ubiquitin-conjugating enzyme E2 variant 1 | [57] | 1.19[58] | 0.98[59] | 1.03[60] | 1.36[61] | 0.41[62] | -2.32[63] |
10 | IKBKG | NF-kappa-B essential modulator | [64] | 4.17[65] | 4.30[66] | 1.96[67] | 4.40[68] | 2.89[69] | 2.08[70] |
11 | IRAK1 | Interleukin-1 receptor-associated kinase 1 | [71] | 6.48[72] | 5.85[73] | 4.74[74] | 6.04[75] | 6.12[76] | 2.00[77] |
12 | UBE2N | Ubiquitin-conjugating enzyme E2 N | [78] | 5.75[79] | 6.21[80] | 4.94[81] | 5.57[82] | 5.16[83] | 1.97[84] |
13 | NFKB2 | Nuclear factor NF-kappa-B p100 subunit | [85] | 4.29[86] | 4.58[87] | 4.93[88] | 3.87[89] | 4.42[90] | -0.33[91] |
14 | RELA | Transcription factor p65 | [92] | 5.20[93] | 4.67[94] | 4.72[95] | 5.19[96] | 4.80[97] | 1.81[98] |
15 | NFKBIB | NF-kappa-B inhibitor beta | [99] | 3.90[100] | 3.70[101] | 3.94[102] | 3.43[103] | 3.48[104] | 0.96[105] |
16 | TAB2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 | [106] | 5.43[107] | 5.57[108] | 5.75[109] | 6.95[110] | 6.11[111] | 2.93[112] |
17 | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7 | [113] | 4.96[114] | 6.01[115] | 5.79[116] | 5.74[117] | 5.62[118] | 2.94[119] |
18 | IRAK2 | Interleukin-1 receptor-associated kinase-like 2 | [120] | 4.98[121] | 5.07[122] | 4.76[123] | 2.82[124] | 4.07[125] | 1.67[126] |
19 | NKIRAS2 | NF-kappa-B inhibitor-interacting Ras-like protein 2 | [127] | 5.82[128] | 4.54[129] | 5.52[130] | 5.83[131] | 5.33[132] | 2.89[133] |
20 | TAB3 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 | [134] | 5.12[135] | 7.04[136] | 7.05[137] | 5.60[138] | 6.50[139] | 3.52[140] |
21 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [141] | 5.73[142] | 5.39[143] | 5.09[144] | 5.00[145] | 5.61[146] | 3.14[147] |
22 | NKIRAS1 | NF-kappa-B inhibitor-interacting Ras-like protein 1 | [148] | 3.69[149] | 3.47[150] | 4.60[151] | 4.70[152] | 4.69[153] | 2.46[154] |
23 | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2 | [155] | 4.49[156] | 5.07[157] | 4.99[158] | 5.05[159] | 4.72[160] | 1.56[161] |
24 | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha | [162] | 5.96[163] | 7.16[164] | 7.04[165] | 5.90[166] | 6.42[167] | 4.20[168] |
25 | TAB1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | [169] | 5.71[170] | 6.33[171] | 6.32[172] | 5.26[173] | 5.30[174] | 2.91[175] |
26 | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta | [176] | 5.58[177] | 5.62[178] | 5.64[179] | 5.51[180] | 5.30[181] | 3.87[182] |
27 | TRAF6 | TNF receptor-associated factor 6 | [183] | 6.15[184] | 6.02[185] | 6.50[186] | 6.91[187] | 6.07[188] | 5.60[189] |
28 | NOD2 | Nucleotide-binding oligomerization domain-containing protein 2 | [190] | 3.16[191] | 1.17[192] | [193] | 1.64[194] | 4.89[195] | 2.16[196] |
29 | S100A12 | Protein S100-A12 | [197] | [198] | [199] | [200] | [201] | [202] | 2.97[203] |
30 | NOD1 | Nucleotide-binding oligomerization domain-containing protein 1 | [204] | 6.08[205] | 5.74[206] | 6.45[207] | 7.49[208] | 6.82[209] | 4.77[210] |
31 | AGER | Advanced glycosylation end product-specific receptor | [211] | 4.02[212] | 7.17[213] | 6.01[214] | 5.89[215] | 5.36[216] | 2.58[217] |
32 | S100B | Protein S100-B | [218] | 1.20[219] | 0.21[220] | [221] | 3.49[222] | -0.82[223] | 3.84[224] |