REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLUCOSE_DEPENDENT_INS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | SEC11C | Signal peptidase complex catalytic subunit SEC11C | [1] | -2.62[2] | -1.22[3] | -3.49[4] | -2.54[5] | -3.97[6] | -0.90[7] |
2 | SEC11A | Signal peptidase complex catalytic subunit SEC11A | [8] | -0.22[9] | -0.41[10] | -0.30[11] | -0.03[12] | -0.65[13] | -1.63[14] |
3 | SPCS1 | Signal peptidase complex subunit 1 | [15] | -0.74[16] | -1.50[17] | -2.33[18] | -1.25[19] | -0.89[20] | -0.27[21] |
4 | SPCS2 | Signal peptidase complex subunit 2 | [22] | 1.85[23] | 1.05[24] | 0.45[25] | 1.66[26] | 1.29[27] | 1.49[28] |
5 | SPCS3 | Signal peptidase complex subunit 3 | [29] | 1.37[30] | 1.59[31] | 2.20[32] | 2.28[33] | 2.24[34] | 2.20[35] |
6 | DPP4 | Dipeptidyl peptidase 4 | [36] | 1.44[37] | 2.20[38] | 2.30[39] | 0.77[40] | 1.64[41] | 0.56[42] |
7 | GATA4 | Transcription factor GATA-4 | [43] | 2.27[44] | 1.47[45] | 2.97[46] | 0.56[47] | 3.13[48] | 1.71[49] |
8 | PAX6 | Paired box protein Pax-6 | [50] | 7.16[51] | 4.74[52] | 6.48[53] | 6.53[54] | 3.00[55] | 3.48[56] |
9 | GPR119 | Glucose-dependent insulinotropic receptor | [57] | 1.56[58] | 2.95[59] | -0.71[60] | [61] | [62] | [63] |
10 | PCSK1 | Neuroendocrine convertase 1 | [64] | -1.88[65] | 1.00[66] | 1.27[67] | 6.09[68] | 7.52[69] | 6.33[70] |
11 | FFAR1 | Free fatty acid receptor 1 | [71] | [72] | [73] | [74] | [75] | [76] | [77] |
12 | ISL1 | Insulin gene enhancer protein ISL-1 | [78] | [79] | [80] | [81] | [82] | [83] | [84] |
13 | GIP | Gastric inhibitory polypeptide | [85] | [86] | [87] | [88] | [89] | [90] | [91] |