REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLUCAGON_LIKE_PEPTIDE_1 | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | SEC11C | Signal peptidase complex catalytic subunit SEC11C | [1] | -3.68[2] | -1.77[3] | -4.32[4] | -3.64[5] | -4.78[6] | -1.30[7] |
2 | SEC11A | Signal peptidase complex catalytic subunit SEC11A | [8] | -1.28[9] | -0.96[10] | -1.13[11] | -1.12[12] | -1.46[13] | -2.03[14] |
3 | SPCS1 | Signal peptidase complex subunit 1 | [15] | -1.80[16] | -2.05[17] | -3.16[18] | -2.34[19] | -1.70[20] | -0.67[21] |
4 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | [22] | 1.44[23] | 1.22[24] | 0.53[25] | 1.97[26] | 1.68[27] | -0.51[28] |
5 | CTNNB1 | Catenin beta-1 | [29] | 2.05[30] | 1.30[31] | 1.99[32] | 1.44[33] | 1.58[34] | 1.83[35] |
6 | SPCS2 | Signal peptidase complex subunit 2 | [36] | 0.79[37] | 0.50[38] | -0.38[39] | 0.56[40] | 0.47[41] | 1.10[42] |
7 | SPCS3 | Signal peptidase complex subunit 3 | [43] | 0.31[44] | 1.04[45] | 1.37[46] | 1.19[47] | 1.43[48] | 1.81[49] |
8 | DPP4 | Dipeptidyl peptidase 4 | [50] | 0.38[51] | 1.65[52] | 1.47[53] | -0.32[54] | 0.83[55] | 0.16[56] |
9 | TCF7L2 | Transcription factor 7-like 2 | [57] | 1.30[58] | 1.83[59] | 1.82[60] | 1.38[61] | 1.27[62] | 2.44[63] |
10 | PAX6 | Paired box protein Pax-6 | [64] | 6.10[65] | 4.19[66] | 5.65[67] | 5.44[68] | 2.19[69] | 3.09[70] |
11 | GPR119 | Glucose-dependent insulinotropic receptor | [71] | 0.50[72] | 2.40[73] | -1.54[74] | [75] | [76] | [77] |
12 | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 | [78] | 2.02[79] | 4.03[80] | 3.12[81] | 1.69[82] | 4.32[83] | -0.96[84] |
13 | PCSK1 | Neuroendocrine convertase 1 | [85] | -2.94[86] | 0.45[87] | 0.43[88] | 5.00[89] | 6.71[90] | 5.93[91] |
14 | LEP | Leptin | [92] | -0.90[93] | -0.16[94] | -0.91[95] | -0.17[96] | -1.58[97] | 3.03[98] |
15 | CDX2 | Homeobox protein CDX-2 | [99] | 3.17[100] | 2.55[101] | 11.77[102] | 2.17[103] | 1.31[104] | -0.60[105] |
16 | GNG13 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 | [106] | [107] | [108] | [109] | [110] | [111] | |
17 | GNAT3 | Guanine nucleotide-binding protein G(t) subunit alpha-3 | [112] | [113] | [114] | [115] | [116] | [117] | [118] |
18 | FFAR1 | Free fatty acid receptor 1 | [119] | [120] | [121] | [122] | [123] | [124] | [125] |
19 | GCG | Glucagon | [126] | [127] | [128] | [129] | [130] | [131] | [132] |
20 | FFAR4 | Free fatty acid receptor 4 | [133] | [134] | [135] | [136] | [137] | [138] | [139] |
21 | GRP | Gastrin-releasing peptide | [140] | [141] | [142] | [143] | [144] | [145] | [146] |