REACTOME_SYNTHESIS_OF_PYROPHOSPHATES_IN_THE_CYTOSOL Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 NUDT3 Diphosphoinositol polyphosphate phosphohydrolase 1 [1] -0.61[2] -0.85[3] -1.28[4] -1.09[5] -1.89[6] -0.67[7]
2 NUDT4 Diphosphoinositol polyphosphate phosphohydrolase 2 [8] -3.96[9] -4.08[10] -3.50[11] -4.67[12] -5.38[13] -4.43[14]
3 ITPK1 Inositol-tetrakisphosphate 1-kinase [15] 1.13[16] 0.17[17] -0.95[18] 0.17[19] 0.01[20] 0.10[21]
4 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 -0.16[22] 1.99[23] 2.23[24] 1.76[25] 1.42[26] 2.03[27]
5 IP6K1 Inositol hexakisphosphate kinase 1 [28] 1.60[29] 1.60[30] 2.37[31] 1.55[32] 2.18[33] 1.43[34]
6 IPPK Inositol-pentakisphosphate 2-kinase [35] -0.01[36] 0.12[37] -0.29[38] 0.40[39] 0.69[40] -0.24[41]
7 IP6K3 Inositol hexakisphosphate kinase 3 [42] -2.41[43] -5.52[44] -8.74[45] -3.69[46] 0.94[47] -0.18[48]
8 PPIP5K1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 2.17[49] 2.77[50] 2.69[51] 3.29[52] 2.42[53] 2.26[54]
9 NUDT11 Diphosphoinositol polyphosphate phosphohydrolase 3-beta [55] [56] [57] -5.97[58] 1.54[59] 2.84[60] -2.70[61]
10 NUDT10 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha [62] [63] -5.27[64] [65] -0.83[66] 0.24[67] 2.25[68]
[1]
ref_hepatocyte NUDT3
Mean 15.3
Standard deviation 13
Values 35 23 8.7 5.7 4.1
[2]
HepG2 NUDT3
Mean 24.4
Standard deviation 3
Values 26 22
[3]
HepG2.C3A NUDT3
Mean 17.3
Standard deviation 3.5
Values 15 20
[4]
HuH.7 NUDT3
Mean 10.1
Standard deviation 2.4
Values 12 7.5 11
[5]
SNU475 NUDT3
Mean 11.9
Standard deviation 1.3
Values 13 11
[6]
THLE NUDT3
Mean 8.94
Standard deviation 2.2
Values 7.4 11
[7]
liver NUDT3
Mean 15.7
Standard deviation 1.7
Values 17 16 17 13
[8]
ref_hepatocyte NUDT4
Mean 13.5
Standard deviation 5.1
Values 21 17 12 8.2 10
[9]
HepG2 NUDT4
Mean 2.12
Standard deviation 0.61
Values 1.7 2.6
[10]
HepG2.C3A NUDT4
Mean 1.63
Standard deviation 0.12
Values 1.7 1.5
[11]
HuH.7 NUDT4
Mean 1.93
Standard deviation 0.56
Values 1.3 2.4 2.1
[12]
SNU475 NUDT4
Mean 0.883
Standard deviation 0.28
Values 0.68 1.1
[13]
THLE NUDT4
Mean 0.705
Standard deviation 0.24
Values 0.54 0.87
[14]
liver NUDT4
Mean 1.03
Standard deviation 0.14
Values 1.1 1.1 0.82 1.1
[15]
ref_hepatocyte ITPK1
Mean 9.61
Standard deviation 4.1
Values 4.5 7 9.1 13 14
[16]
HepG2 ITPK1
Mean 51.3
Standard deviation 10
Values 59 44
[17]
HepG2.C3A ITPK1
Mean 22.1
Standard deviation 0.46
Values 22 22
[18]
HuH.7 ITPK1
Mean 8.02
Standard deviation 1.6
Values 9.6 6.4 8
[19]
SNU475 ITPK1
Mean 18
Standard deviation 3
Values 20 16
[20]
THLE ITPK1
Mean 21
Standard deviation 2.6
Values 19 23
[21]
liver ITPK1
Mean 16.9
Standard deviation 6.6
Values 14 11 16 26
[22]
ref_hepatocyte PPIP5K2
Mean 3.26
Standard deviation 1.5
Values 4.5 4.6 1.9 1.4 3.9
[23]
HepG2 PPIP5K2
Mean 7.1
Standard deviation 3.6
Values 4.5 9.7
[24]
HepG2.C3A PPIP5K2
Mean 26.4
Standard deviation 8.5
Values 20 32
[25]
HuH.7 PPIP5K2
Mean 24.8
Standard deviation 3.5
Values 29 22 24
[26]
SNU475 PPIP5K2
Mean 18.4
Standard deviation 4.2
Values 21 15
[27]
THLE PPIP5K2
Mean 18.9
Standard deviation 2.3
Values 21 17
[28]
liver PPIP5K2
Mean 21.9
Standard deviation 3.7
Values 20 27 21 19
[29]
ref_hepatocyte IP6K1
Mean 2.97
Standard deviation 1.3
Values 2.3 2.8 5 3.3 1.6
[30]
HepG2 IP6K1
Mean 22
Standard deviation 0.47
Values 22 22
[31]
HepG2.C3A IP6K1
Mean 18.4
Standard deviation 2.5
Values 20 17
[32]
HuH.7 IP6K1
Mean 24.8
Standard deviation 2.7
Values 27 25 22
[33]
SNU475 IP6K1
Mean 14.5
Standard deviation 0.0032
Values 15 15
[34]
THLE IP6K1
Mean 29.2
Standard deviation 5.1
Values 26 33
[35]
liver IP6K1
Mean 13.1
Standard deviation 2
Values 10 14 14 15
[36]
ref_hepatocyte IPPK
Mean 2.74
Standard deviation 2.5
Values 4.8 6 1 0.94 0.92
[37]
HepG2 IPPK
Mean 6.65
Standard deviation 0.28
Values 6.5 6.9
[38]
HepG2.C3A IPPK
Mean 6.08
Standard deviation 1.5
Values 5.1 7.1
[39]
HuH.7 IPPK
Mean 3.62
Standard deviation 0.65
Values 3.9 2.9 4.1
[40]
SNU475 IPPK
Mean 6.05
Standard deviation 0.4
Values 5.8 6.3
[41]
THLE IPPK
Mean 9.63
Standard deviation 1.4
Values 8.6 11
[42]
liver IPPK
Mean 3.8
Standard deviation 1.6
Values 1.6 5.5 4 4.1
[43]
ref_hepatocyte IP6K3
Mean 2.42
Standard deviation 2.8
Values 0.35 0.43 4.1 6.6 0.62
[44]
HepG2 IP6K3
Mean 1.11
Standard deviation 0.92
Values 1.8 0.46
[45]
HepG2.C3A IP6K3
Mean 0.108
Standard deviation 0.015
Values 0.097 0.12
[46]
HuH.7 IP6K3
Mean 0.00915
Standard deviation 0.0097
Values 0.0082 0.019 0
[47]
SNU475 IP6K3
Mean 0.312
Standard deviation 0.061
Values 0.27 0.35
[48]
THLE IP6K3
Mean 10
Standard deviation 2.2
Values 12 8.5
[49]
liver IP6K3
Mean 3.51
Standard deviation 2.7
Values 4.3 1.1 1.7 6.9
[50]
ref_hepatocyte PPIP5K1
Mean 0.861
Standard deviation 0.24
Values 1.2 0.68 0.77 1 0.63
[51]
HepG2 PPIP5K1
Mean 9.48
Standard deviation 0.37
Values 9.2 9.7
[52]
HepG2.C3A PPIP5K1
Mean 12
Standard deviation 0.86
Values 11 13
[53]
HuH.7 PPIP5K1
Mean 8.96
Standard deviation 2.2
Values 11 7.3 8.1
[54]
SNU475 PPIP5K1
Mean 14
Standard deviation 2.2
Values 16 12
[55]
THLE PPIP5K1
Mean 9.99
Standard deviation 0.22
Values 10 9.8
[56]
liver PPIP5K1
Mean 6.77
Standard deviation 3.9
Values 2.9 12 5.6 6.5
[57]
ref_hepatocyte NUDT11
Mean 0.106
Standard deviation 0.1
Values 0 0.2 0.11 0 0.22
[58]
HepG2 NUDT11
Mean 0
Standard deviation 0
Values 0 0
[59]
HepG2.C3A NUDT11
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 NUDT11
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[61]
SNU475 NUDT11
Mean 0.512
Standard deviation 0.042
Values 0.48 0.54
[62]
THLE NUDT11
Mean 1.64
Standard deviation 0.79
Values 1.1 2.2
[63]
liver NUDT11
Mean 0.0269
Standard deviation 0.024
Values 0 0.043 0.051 0.013
[64]
ref_hepatocyte NUDT10
Mean 0.0915
Standard deviation 0.14
Values 0 0 0.33 0.069 0.057
[65]
HepG2 NUDT10
Mean 0
Standard deviation 0
Values 0 0
[66]
HepG2.C3A NUDT10
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[67]
HuH.7 NUDT10
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 NUDT10
Mean 0.0857
Standard deviation 0.11
Values 0.0093 0.16
[69]
THLE NUDT10
Mean 0.234
Standard deviation 0.11
Values 0.15 0.31
[70]
liver NUDT10
Mean 0.716
Standard deviation 0.11
Values 0.87 0.6 0.72 0.68