REACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 AKR1C3 Aldo-keto reductase family 1 member C3 [1] -0.45[2] -0.22[3] -6.90[4] 0.76[5] -4.95[6] -1.61[7]
2 PTGES3 Prostaglandin E synthase 3 [8] 1.05[9] 0.99[10] 1.30[11] -0.30[12] 1.00[13] -1.50[14]
3 CBR1 Carbonyl reductase [NADPH] 1 [15] -2.02[16] -2.81[17] -2.56[18] -2.11[19] -1.16[20] -0.90[21]
4 CYP8B1 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase [22] -6.39[23] -4.25[24] -8.21[25] -9.60[26] -10.08[27] 3.03[28]
5 HPGD 15-hydroxyprostaglandin dehydrogenase [NAD(+)] [29] -6.33[30] -6.97[31] 2.13[32] -6.42[33] -5.60[34] 1.20[35]
6 PTGES2 Prostaglandin E synthase 2 [36] 2.27[37] 1.98[38] 1.20[39] -0.10[40] 1.11[41] 0.06[42]
7 PTGR2 Prostaglandin reductase 2 [43] 0.47[44] 1.65[45] 3.49[46] 0.00[47] 1.32[48] 1.20[49]
8 TBXAS1 Thromboxane-A synthase [50] -1.15[51] 0.52[52] -2.71[53] 1.02[54] 0.92[55] 2.23[56]
9 PTGDS Prostaglandin-H2 D-isomerase [57] 2.32[58] 2.10[59] -6.81[60] 0.20[61] 1.67[62] 1.47[63]
10 PTGIS Prostacyclin synthase [64] 0.27[65] 0.99[66] 4.93[67] 1.50[68] 8.80[69] 5.42[70]
11 PTGES Prostaglandin E synthase [71] 3.11[72] -1.14[73] -1.06[74] 3.70[75] 7.56[76] -0.79[77]
12 PTGS1 Prostaglandin G/H synthase 1 [78] 3.17[79] -4.14[80] -2.43[81] 3.06[82] 7.25[83] 3.55[84]
13 HPGDS Hematopoietic prostaglandin D synthase [85] [86] [87] [88] -5.65[89] -2.15[90] 0.54[91]
14 PTGS2 Prostaglandin G/H synthase 2 [92] [93] -1.20[94] -0.98[95] 3.24[96] 10.42[97] 3.41[98]
15 PRXL2B [99] [100] [101] [102] [103] [104] [105]
[1]
ref_hepatocyte AKR1C3
Mean 242
Standard deviation 1.8e+02
Values 99 4.4e+02 1.1e+02 4.3e+02 1.2e+02
[2]
HepG2 AKR1C3
Mean 111
Standard deviation 53
Values 1.5e+02 74
[3]
HepG2.C3A AKR1C3
Mean 152
Standard deviation 34
Values 1.8e+02 1.3e+02
[4]
HuH.7 AKR1C3
Mean 1.46
Standard deviation 0.83
Values 1.1 2.4 0.84
[5]
SNU475 AKR1C3
Mean 580
Standard deviation 2.8e+02
Values 7.8e+02 3.9e+02
[6]
THLE AKR1C3
Mean 4.84
Standard deviation 0.00088
Values 4.8 4.8
[7]
liver AKR1C3
Mean 75.4
Standard deviation 53
Values 51 67 1.5e+02 32
[8]
ref_hepatocyte PTGES3
Mean 143
Standard deviation 59
Values 1.7e+02 2.3e+02 1.1e+02 1e+02 97
[9]
HepG2 PTGES3
Mean 184
Standard deviation 15
Values 1.7e+02 1.9e+02
[10]
HepG2.C3A PTGES3
Mean 207
Standard deviation 42
Values 1.8e+02 2.4e+02
[11]
HuH.7 PTGES3
Mean 253
Standard deviation 51
Values 2.8e+02 1.9e+02 2.8e+02
[12]
SNU475 PTGES3
Mean 164
Standard deviation 5.7
Values 1.7e+02 1.6e+02
[13]
THLE PTGES3
Mean 177
Standard deviation 27
Values 1.6e+02 2e+02
[14]
liver PTGES3
Mean 48.2
Standard deviation 31
Values 67 22 82 23
[15]
ref_hepatocyte CBR1
Mean 107
Standard deviation 57
Values 17 92 1.3e+02 1.6e+02 1.4e+02
[16]
HepG2 CBR1
Mean 16.5
Standard deviation 3.2
Values 19 14
[17]
HepG2.C3A CBR1
Mean 11.2
Standard deviation 0.36
Values 11 11
[18]
HuH.7 CBR1
Mean 13.1
Standard deviation 4.3
Values 12 9.3 18
[19]
SNU475 CBR1
Mean 35
Standard deviation 0.8
Values 36 34
[20]
THLE CBR1
Mean 29.6
Standard deviation 3.3
Values 27 32
[21]
liver CBR1
Mean 54.8
Standard deviation 38
Values 97 26 76 19
[22]
ref_hepatocyte CYP8B1
Mean 34.6
Standard deviation 44
Values 1.2 0.33 6.4 79 86
[23]
HepG2 CYP8B1
Mean 0.257
Standard deviation 0.2
Values 0.11 0.4
[24]
HepG2.C3A CYP8B1
Mean 1.33
Standard deviation 0.5
Values 1.7 0.98
[25]
HuH.7 CYP8B1
Mean 0.084
Standard deviation 0.016
Values 0.09 0.096 0.066
[26]
SNU475 CYP8B1
Mean 0.0631
Standard deviation 0.004
Values 0.06 0.066
[27]
THLE CYP8B1
Mean 0.0198
Standard deviation 0.0054
Values 0.024 0.016
[28]
liver CYP8B1
Mean 269
Standard deviation 1.3e+02
Values 4.2e+02 1.3e+02 3e+02 2.2e+02
[29]
ref_hepatocyte HPGD
Mean 29.5
Standard deviation 45
Values 0.17 5.7 1.8 35 1.1e+02
[30]
HepG2 HPGD
Mean 0.23
Standard deviation 0.13
Values 0.14 0.32
[31]
HepG2.C3A HPGD
Mean 0.172
Standard deviation 0.12
Values 0.087 0.26
[32]
HuH.7 HPGD
Mean 92.8
Standard deviation 79
Values 46 1.8e+02 48
[33]
SNU475 HPGD
Mean 0.487
Standard deviation 0.29
Values 0.7 0.28
[34]
THLE HPGD
Mean 0.376
Standard deviation 0.08
Values 0.43 0.32
[35]
liver HPGD
Mean 64.5
Standard deviation 48
Values 25 68 1.3e+02 35
[36]
ref_hepatocyte PTGES2
Mean 13.3
Standard deviation 2.7
Values 12 13 11 18 13
[37]
HepG2 PTGES2
Mean 40
Standard deviation 6.9
Values 45 35
[38]
HepG2.C3A PTGES2
Mean 38.5
Standard deviation 2.5
Values 40 37
[39]
HuH.7 PTGES2
Mean 22.1
Standard deviation 9.4
Values 26 11 29
[40]
SNU475 PTGES2
Mean 17.5
Standard deviation 0.86
Values 17 18
[41]
THLE PTGES2
Mean 17.8
Standard deviation 4.4
Values 15 21
[42]
liver PTGES2
Mean 13.2
Standard deviation 3.7
Values 16 9.8 17 10
[43]
ref_hepatocyte PTGR2
Mean 3.35
Standard deviation 1.8
Values 1.3 4.2 1.8 3.7 5.7
[44]
HepG2 PTGR2
Mean 2.9
Standard deviation 0.79
Values 3.5 2.3
[45]
HepG2.C3A PTGR2
Mean 7.72
Standard deviation 0.089
Values 7.7 7.8
[46]
HuH.7 PTGR2
Mean 27.1
Standard deviation 6.5
Values 28 20 33
[47]
SNU475 PTGR2
Mean 4.74
Standard deviation 0.69
Values 5.2 4.3
[48]
THLE PTGR2
Mean 5.19
Standard deviation 0.14
Values 5.1 5.3
[49]
liver PTGR2
Mean 7.34
Standard deviation 3.3
Values 6.9 6.9 12 3.7
[50]
ref_hepatocyte TBXAS1
Mean 0.896
Standard deviation 0.62
Values 0.56 0.49 0.32 1.7 1.4
[51]
HepG2 TBXAS1
Mean 0.253
Standard deviation 0.096
Values 0.32 0.18
[52]
HepG2.C3A TBXAS1
Mean 0.938
Standard deviation 0.16
Values 1 0.83
[53]
HuH.7 TBXAS1
Mean 0.0986
Standard deviation 0.058
Values 0.12 0.032 0.14
[54]
SNU475 TBXAS1
Mean 2.57
Standard deviation 0.093
Values 2.5 2.6
[55]
THLE TBXAS1
Mean 1.05
Standard deviation 0.095
Values 1.1 0.98
[56]
liver TBXAS1
Mean 4
Standard deviation 1.4
Values 2.1 4.8 4.1 5.1
[57]
ref_hepatocyte PTGDS
Mean 0.485
Standard deviation 0.7
Values 0 0 0 0.9 1.5
[58]
HepG2 PTGDS
Mean 1.51
Standard deviation 1.9
Values 2.8 0.19
[59]
HepG2.C3A PTGDS
Mean 1.52
Standard deviation 1
Values 2.3 0.78
[60]
HuH.7 PTGDS
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[61]
SNU475 PTGDS
Mean 0.785
Standard deviation 0.16
Values 0.67 0.9
[62]
THLE PTGDS
Mean 0.956
Standard deviation 0.028
Values 0.98 0.94
[63]
liver PTGDS
Mean 1.28
Standard deviation 1.1
Values 2.4 0.23 2.1 0.46
[64]
ref_hepatocyte PTGIS
Mean 0.218
Standard deviation 0.14
Values 0.14 0.08 0.32 0.4 0.15
[65]
HepG2 PTGIS
Mean 0.163
Standard deviation 0.012
Values 0.17 0.15
[66]
HepG2.C3A PTGIS
Mean 0.316
Standard deviation 0.0069
Values 0.32 0.31
[67]
HuH.7 PTGIS
Mean 4.77
Standard deviation 0.64
Values 5.5 4.3 4.5
[68]
SNU475 PTGIS
Mean 0.868
Standard deviation 0.11
Values 0.79 0.94
[69]
THLE PTGIS
Mean 59.9
Standard deviation 32
Values 37 82
[70]
liver PTGIS
Mean 8.86
Standard deviation 2.8
Values 5.9 11 12 7.1
[71]
ref_hepatocyte PTGES
Mean 0.18
Standard deviation 0.17
Values 0 0.46 0.21 0.086 0.15
[72]
HepG2 PTGES
Mean 0.97
Standard deviation 0.87
Values 1.6 0.35
[73]
HepG2.C3A PTGES
Mean 0.0598
Standard deviation 0.039
Values 0.087 0.032
[74]
HuH.7 PTGES
Mean 0.062
Standard deviation 0.028
Values 0.041 0.051 0.094
[75]
SNU475 PTGES
Mean 3.29
Standard deviation 1.6
Values 2.2 4.4
[76]
THLE PTGES
Mean 21
Standard deviation 5.9
Values 17 25
[77]
liver PTGES
Mean 0.099
Standard deviation 0.044
Values 0.14 0.071 0.051 0.13
[78]
ref_hepatocyte PTGS1
Mean 0.117
Standard deviation 0.16
Values 0 0 0.13 0.06 0.39
[79]
HepG2 PTGS1
Mean 0.657
Standard deviation 0.75
Values 1.2 0.13
[80]
HepG2.C3A PTGS1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[81]
HuH.7 PTGS1
Mean 0.0156
Standard deviation 0.02
Values 0.0082 0.039 0
[82]
SNU475 PTGS1
Mean 1.38
Standard deviation 0.25
Values 1.5 1.2
[83]
THLE PTGS1
Mean 11
Standard deviation 1.1
Values 10 12
[84]
liver PTGS1
Mean 1.31
Standard deviation 0.36
Values 1.4 1.5 1.6 0.78
[85]
ref_hepatocyte HPGDS
Mean 0.0826
Standard deviation 0.12
Values 0 0 0 0.26 0.15
[86]
HepG2 HPGDS
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A HPGDS
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 HPGDS
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 HPGDS
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[90]
THLE HPGDS
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[91]
liver HPGDS
Mean 0.115
Standard deviation 0.057
Values 0.16 0.1 0.15 0.04
[92]
ref_hepatocyte PTGS2
Mean 0.032
Standard deviation 0.045
Values 0 0 0 0.095 0.065
[93]
HepG2 PTGS2
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A PTGS2
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[95]
HuH.7 PTGS2
Mean 0.0117
Standard deviation 0.013
Values 0 0.026 0.0094
[96]
SNU475 PTGS2
Mean 0.428
Standard deviation 0.51
Values 0.07 0.79
[97]
THLE PTGS2
Mean 27
Standard deviation 7.8
Values 33 22
[98]
liver PTGS2
Mean 0.325
Standard deviation 0.24
Values 0.24 0.67 0.13 0.26
[99]
ref_hepatocyte PRXL2B
Missing
[100]
HepG2 PRXL2B
Missing
[101]
HepG2.C3A PRXL2B
Missing
[102]
HuH.7 PRXL2B
Missing
[103]
SNU475 PRXL2B
Missing
[104]
THLE PRXL2B
Missing
[105]
liver PRXL2B
Missing