REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MTMR4 Myotubularin-related protein 4 [1] -0.32[2] -0.28[3] -0.13[4] -2.00[5] -1.47[6] 0.18[7]
2 PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 [8] -0.58[9] -0.76[10] -1.88[11] -0.61[12] -0.51[13] -1.53[14]
3 VAC14 Protein VAC14 homolog [15] 0.40[16] -0.78[17] -0.36[18] -0.99[19] 0.09[20] -1.26[21]
4 MTM1 Myotubularin [22] -1.24[23] -0.74[24] -2.00[25] -1.75[26] -1.99[27] -1.00[28]
5 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 0.70[29] 1.47[30] 1.41[31] 1.63[32] 0.82[33] 1.49[34]
6 MTMR2 Myotubularin-related protein 2 [35] 0.79[36] 0.68[37] -1.33[38] 1.41[39] 1.24[40] -1.70[41]
7 PIK3R4 Phosphoinositide 3-kinase regulatory subunit 4 [42] 0.20[43] -0.55[44] 0.22[45] 0.25[46] 0.61[47] 0.71[48]
8 PIKFYVE 1-phosphatidylinositol 3-phosphate 5-kinase [49] 0.21[50] 1.06[51] 1.97[52] 1.22[53] 1.01[54] 1.20[55]
9 FIG4 Polyphosphoinositide phosphatase [56] -0.32[57] -0.92[58] -1.15[59] -0.34[60] -0.57[61] -1.22[62]
10 MTMR9 Myotubularin-related protein 9 [63] 0.05[64] -0.32[65] -0.73[66] -0.18[67] 0.76[68] 0.72[69]
11 MTMR7 Myotubularin-related protein 7 [70] -0.02[71] 1.43[72] 1.92[73] 0.33[74] 0.25[75] 1.09[76]
[1]
ref_hepatocyte MTMR4
Mean 6.86
Standard deviation 3.5
Values 11 5.3 2 6.5 9.8
[2]
HepG2 MTMR4
Mean 23.6
Standard deviation 2.3
Values 22 25
[3]
HepG2.C3A MTMR4
Mean 37.9
Standard deviation 2.1
Values 39 36
[4]
HuH.7 MTMR4
Mean 46.4
Standard deviation 18
Values 38 67 34
[5]
SNU475 MTMR4
Mean 8.44
Standard deviation 2.5
Values 10 6.7
[6]
THLE MTMR4
Mean 14.7
Standard deviation 0.29
Values 14 15
[7]
liver MTMR4
Mean 49.4
Standard deviation 19
Values 29 70 37 61
[8]
ref_hepatocyte PIK3C3
Mean 4.59
Standard deviation 2.3
Values 8 5.9 2.3 3.8 3
[9]
HepG2 PIK3C3
Mean 13.2
Standard deviation 3.3
Values 11 16
[10]
HepG2.C3A PIK3C3
Mean 18.2
Standard deviation 1.3
Values 17 19
[11]
HuH.7 PIK3C3
Mean 9.26
Standard deviation 1.9
Values 9.1 11 7.5
[12]
SNU475 PIK3C3
Mean 14.7
Standard deviation 3.2
Values 17 12
[13]
THLE PIK3C3
Mean 19.1
Standard deviation 0.92
Values 18 20
[14]
liver PIK3C3
Mean 10.1
Standard deviation 4.2
Values 6.9 15 6.8 11
[15]
ref_hepatocyte VAC14
Mean 4.46
Standard deviation 1.4
Values 3.8 2.9 6.2 5.7 3.7
[16]
HepG2 VAC14
Mean 25.3
Standard deviation 2.2
Values 27 24
[17]
HepG2.C3A VAC14
Mean 17.4
Standard deviation 0.12
Values 18 17
[18]
HuH.7 VAC14
Mean 25.7
Standard deviation 7.6
Values 34 18 25
[19]
SNU475 VAC14
Mean 11
Standard deviation 2
Values 12 9.6
[20]
THLE VAC14
Mean 28.2
Standard deviation 2.3
Values 27 30
[21]
liver VAC14
Mean 11.8
Standard deviation 3.3
Values 11 9.7 17 10
[22]
ref_hepatocyte MTM1
Mean 3.45
Standard deviation 2
Values 6.4 1.8 2.2 2.3 4.6
[23]
HepG2 MTM1
Mean 6.28
Standard deviation 2.9
Values 4.2 8.4
[24]
HepG2.C3A MTM1
Mean 13.9
Standard deviation 2.9
Values 12 16
[25]
HuH.7 MTM1
Mean 6.39
Standard deviation 0.87
Values 7.2 5.5 6.5
[26]
SNU475 MTM1
Mean 5.05
Standard deviation 0.37
Values 5.3 4.8
[27]
THLE MTM1
Mean 5.14
Standard deviation 0.006
Values 5.1 5.1
[28]
liver MTM1
Mean 11
Standard deviation 1
Values 11 11 12 9.8
[29]
ref_hepatocyte PIK3C2A
Mean 2.52
Standard deviation 0.94
Values 3.9 2.7 2.4 1.4 2.2
[30]
HepG2 PIK3C2A
Mean 17.6
Standard deviation 8.6
Values 12 24
[31]
HepG2.C3A PIK3C2A
Mean 46.9
Standard deviation 9.1
Values 40 53
[32]
HuH.7 PIK3C2A
Mean 49.6
Standard deviation 15
Values 55 61 33
[33]
SNU475 PIK3C2A
Mean 38.5
Standard deviation 0.63
Values 39 38
[34]
THLE PIK3C2A
Mean 26.4
Standard deviation 7
Values 31 21
[35]
liver PIK3C2A
Mean 45.2
Standard deviation 21
Values 26 67 29 59
[36]
ref_hepatocyte MTMR2
Mean 2.23
Standard deviation 1.7
Values 4.3 3.8 1.7 0.64 0.76
[37]
HepG2 MTMR2
Mean 16.6
Standard deviation 3.5
Values 14 19
[38]
HepG2.C3A MTMR2
Mean 23.9
Standard deviation 7
Values 19 29
[39]
HuH.7 MTMR2
Mean 6.56
Standard deviation 0.94
Values 7.5 5.7 6.4
[40]
SNU475 MTMR2
Mean 29.1
Standard deviation 1.7
Values 30 28
[41]
THLE MTMR2
Mean 31.2
Standard deviation 3
Values 29 33
[42]
liver MTMR2
Mean 4.35
Standard deviation 0.41
Values 3.9 4.5 4.8 4.2
[43]
ref_hepatocyte PIK3R4
Mean 1.95
Standard deviation 0.81
Values 1.4 1.7 1.2 2.4 3.2
[44]
HepG2 PIK3R4
Mean 9.67
Standard deviation 3.2
Values 7.4 12
[45]
HepG2.C3A PIK3R4
Mean 8.97
Standard deviation 1.7
Values 7.8 10
[46]
HuH.7 PIK3R4
Mean 16.8
Standard deviation 2.8
Values 20 14 16
[47]
SNU475 PIK3R4
Mean 11.4
Standard deviation 0.1
Values 11 11
[48]
THLE PIK3R4
Mean 17.7
Standard deviation 1.3
Values 17 19
[49]
liver PIK3R4
Mean 20.3
Standard deviation 7.7
Values 15 27 12 27
[50]
ref_hepatocyte PIKFYVE
Mean 1.85
Standard deviation 1.2
Values 3.9 1.8 1.6 0.78 1.2
[51]
HepG2 PIKFYVE
Mean 9.2
Standard deviation 3.3
Values 6.9 12
[52]
HepG2.C3A PIKFYVE
Mean 25.9
Standard deviation 0.91
Values 25 27
[53]
HuH.7 PIKFYVE
Mean 53.6
Standard deviation 12
Values 60 61 40
[54]
SNU475 PIKFYVE
Mean 21.1
Standard deviation 3.8
Values 24 18
[55]
THLE PIKFYVE
Mean 22
Standard deviation 0.21
Values 22 22
[56]
liver PIKFYVE
Mean 27
Standard deviation 16
Values 15 40 12 41
[57]
ref_hepatocyte FIG4
Mean 1.71
Standard deviation 0.91
Values 1.9 3 0.54 1.9 1.3
[58]
HepG2 FIG4
Mean 5.9
Standard deviation 1.3
Values 5 6.8
[59]
HepG2.C3A FIG4
Mean 6.08
Standard deviation 0.039
Values 6.1 6
[60]
HuH.7 FIG4
Mean 5.7
Standard deviation 0.56
Values 5.9 5.1 6.1
[61]
SNU475 FIG4
Mean 6.63
Standard deviation 2.6
Values 8.5 4.8
[62]
THLE FIG4
Mean 6.84
Standard deviation 0.27
Values 6.6 7
[63]
liver FIG4
Mean 4.67
Standard deviation 1.1
Values 4.2 5.1 5.9 3.5
[64]
ref_hepatocyte MTMR9
Mean 0.96
Standard deviation 0.48
Values 0.85 1.7 1.1 0.59 0.54
[65]
HepG2 MTMR9
Mean 4.28
Standard deviation 0.48
Values 3.9 4.6
[66]
HepG2.C3A MTMR9
Mean 5.16
Standard deviation 0.36
Values 4.9 5.4
[67]
HuH.7 MTMR9
Mean 4.3
Standard deviation 0.84
Values 5.3 3.8 3.9
[68]
SNU475 MTMR9
Mean 4.17
Standard deviation 0.23
Values 4.3 4
[69]
THLE MTMR9
Mean 9.65
Standard deviation 0.37
Values 9.9 9.4
[70]
liver MTMR9
Mean 10
Standard deviation 3.7
Values 6.9 14 7 12
[71]
ref_hepatocyte MTMR7
Mean 0.103
Standard deviation 0.13
Values 0 0 0.32 0.1 0.098
[72]
HepG2 MTMR7
Mean 0.439
Standard deviation 0.07
Values 0.39 0.49
[73]
HepG2.C3A MTMR7
Mean 1.86
Standard deviation 0.4
Values 2.1 1.6
[74]
HuH.7 MTMR7
Mean 2.89
Standard deviation 0.92
Values 2.3 3.9 2.5
[75]
SNU475 MTMR7
Mean 0.637
Standard deviation 0.074
Values 0.58 0.69
[76]
THLE MTMR7
Mean 0.729
Standard deviation 0.25
Values 0.91 0.55
[77]
liver MTMR7
Mean 1.4
Standard deviation 0.5
Values 1.1 1.7 0.9 1.9