REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ARF1 ADP-ribosylation factor 1 [1] -1.05[2] -1.17[3] -1.16[4] -0.94[5] -1.19[6] -1.09[7]
2 ARF3 ADP-ribosylation factor 3 [8] 1.75[9] 1.27[10] 1.22[11] 1.66[12] 1.43[13] -0.57[14]
3 PI4K2B Phosphatidylinositol 4-kinase type 2-beta [15] 0.06[16] 0.54[17] 0.65[18] -1.01[19] -0.99[20] 0.43[21]
4 PI4KA Phosphatidylinositol 4-kinase alpha [22] 1.03[23] 0.77[24] 0.98[25] 0.54[26] 0.82[27] 1.18[28]
5 PI4KB Phosphatidylinositol 4-kinase beta [29] 0.73[30] 0.18[31] 0.24[32] 1.35[33] 1.30[34] 0.36[35]
6 SACM1L Phosphatidylinositide phosphatase SAC1 [36] -0.10[37] 0.72[38] 0.38[39] -0.12[40] 0.75[41] 0.71[42]
7 PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 [43] 0.52[44] 0.83[45] -0.47[46] 0.47[47] 0.76[48] 0.24[49]
8 VAC14 Protein VAC14 homolog [50] 1.50[51] 0.81[52] 1.05[53] 0.10[54] 1.36[55] 0.51[56]
9 PI4K2A Phosphatidylinositol 4-kinase type 2-alpha [57] 1.20[58] 1.16[59] 0.37[60] 0.57[61] 1.65[62] 0.26[63]
10 OCRL Inositol polyphosphate 5-phosphatase OCRL-1 [64] 2.20[65] 2.19[66] 2.28[67] 2.07[68] 2.07[69] 0.87[70]
11 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1.80[71] 3.06[72] 2.82[73] 2.72[74] 2.09[75] 3.26[76]
12 PIK3R4 Phosphoinositide 3-kinase regulatory subunit 4 [77] 1.30[78] 1.04[79] 1.63[80] 1.33[81] 1.88[82] 2.48[83]
13 PIKFYVE 1-phosphatidylinositol 3-phosphate 5-kinase [84] 1.31[85] 2.65[86] 3.38[87] 2.31[88] 2.28[89] 2.97[90]
14 FIG4 Polyphosphoinositide phosphatase [91] 0.78[92] 0.67[93] 0.26[94] 0.74[95] 0.70[96] 0.55[97]
15 INPP5E 72 kDa inositol polyphosphate 5-phosphatase [98] 0.88[99] 0.74[100] -0.41[101] 0.83[102] 1.02[103] -0.43[104]
16 PIK3C2G Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma -7.89[105] [106] 0.10[107] -3.68[108] -9.84[109] 3.99[110]
17 TPTE2 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 [111] -2.32[112] -0.73[113] -2.34[114] -1.95[115] -2.82[116] -3.99[117]
18 TPTE Putative tyrosine-protein phosphatase TPTE [118] [119] -3.07[120] 4.12[121] 2.92[122] -3.48[123] -4.40[124]
[1]
ref_hepatocyte ARF1
Mean 151
Standard deviation 27
Values 1.7e+02 1.8e+02 1.6e+02 1.4e+02 1.1e+02
[2]
HepG2 ARF1
Mean 146
Standard deviation 9
Values 1.5e+02 1.4e+02
[3]
HepG2.C3A ARF1
Mean 150
Standard deviation 24
Values 1.7e+02 1.3e+02
[4]
HuH.7 ARF1
Mean 189
Standard deviation 16
Values 1.8e+02 2.1e+02 1.8e+02
[5]
SNU475 ARF1
Mean 183
Standard deviation 24
Values 2e+02 1.7e+02
[6]
THLE ARF1
Mean 163
Standard deviation 16
Values 1.5e+02 1.7e+02
[7]
liver ARF1
Mean 133
Standard deviation 83
Values 1.9e+02 61 2.2e+02 63
[8]
ref_hepatocyte ARF3
Mean 11.8
Standard deviation 2.5
Values 8.9 16 11 12 11
[9]
HepG2 ARF3
Mean 79.6
Standard deviation 15
Values 69 90
[10]
HepG2.C3A ARF3
Mean 63.5
Standard deviation 19
Values 50 77
[11]
HuH.7 ARF3
Mean 76.5
Standard deviation 26
Values 1e+02 50 79
[12]
SNU475 ARF3
Mean 86.5
Standard deviation 19
Values 1e+02 73
[13]
THLE ARF3
Mean 78.2
Standard deviation 16
Values 67 90
[14]
liver ARF3
Mean 14.9
Standard deviation 0.86
Values 15 14 15 16
[15]
ref_hepatocyte PI4K2B
Mean 9.12
Standard deviation 4.6
Values 13 9.2 4.5 4.4 14
[16]
HepG2 PI4K2B
Mean 19.1
Standard deviation 9.8
Values 12 26
[17]
HepG2.C3A PI4K2B
Mean 29.6
Standard deviation 12
Values 21 38
[18]
HuH.7 PI4K2B
Mean 39.8
Standard deviation 4
Values 43 36 40
[19]
SNU475 PI4K2B
Mean 10.5
Standard deviation 2.4
Values 12 8.7
[20]
THLE PI4K2B
Mean 11.2
Standard deviation 3
Values 9.1 13
[21]
liver PI4K2B
Mean 23
Standard deviation 5.7
Values 21 29 16 26
[22]
ref_hepatocyte PI4KA
Mean 7.12
Standard deviation 3.1
Values 6.7 4.7 6.6 12 5.3
[23]
HepG2 PI4KA
Mean 29.3
Standard deviation 1.6
Values 30 28
[24]
HepG2.C3A PI4KA
Mean 27.2
Standard deviation 5.6
Values 31 23
[25]
HuH.7 PI4KA
Mean 39
Standard deviation 6.4
Values 46 38 33
[26]
SNU475 PI4KA
Mean 24
Standard deviation 5.8
Values 28 20
[27]
THLE PI4KA
Mean 30.8
Standard deviation 4
Values 28 34
[28]
liver PI4KA
Mean 30.2
Standard deviation 9.3
Values 18 39 28 35
[29]
ref_hepatocyte PI4KB
Mean 6.37
Standard deviation 2.6
Values 5 11 6.1 4.9 5
[30]
HepG2 PI4KB
Mean 21.2
Standard deviation 1.3
Values 20 22
[31]
HepG2.C3A PI4KB
Mean 16.1
Standard deviation 1.7
Values 17 15
[32]
HuH.7 PI4KB
Mean 20.9
Standard deviation 1.5
Values 22 19 21
[33]
SNU475 PI4KB
Mean 37.5
Standard deviation 3.8
Values 40 35
[34]
THLE PI4KB
Mean 38.5
Standard deviation 2.8
Values 37 40
[35]
liver PI4KB
Mean 15.2
Standard deviation 4.3
Values 19 11 19 12
[36]
ref_hepatocyte SACM1L
Mean 6.21
Standard deviation 2.2
Values 7.7 8.6 3.2 4.8 6.7
[37]
HepG2 SACM1L
Mean 11.6
Standard deviation 5.1
Values 8 15
[38]
HepG2.C3A SACM1L
Mean 22.9
Standard deviation 5.9
Values 19 27
[39]
HuH.7 SACM1L
Mean 22.5
Standard deviation 0.55
Values 23 22 23
[40]
SNU475 SACM1L
Mean 13.2
Standard deviation 1.7
Values 14 12
[41]
THLE SACM1L
Mean 25.6
Standard deviation 2
Values 24 27
[42]
liver SACM1L
Mean 19
Standard deviation 2.5
Values 22 19 19 16
[43]
ref_hepatocyte PIK3C3
Mean 4.59
Standard deviation 2.3
Values 8 5.9 2.3 3.8 3
[44]
HepG2 PIK3C3
Mean 13.2
Standard deviation 3.3
Values 11 16
[45]
HepG2.C3A PIK3C3
Mean 18.2
Standard deviation 1.3
Values 17 19
[46]
HuH.7 PIK3C3
Mean 9.26
Standard deviation 1.9
Values 9.1 11 7.5
[47]
SNU475 PIK3C3
Mean 14.7
Standard deviation 3.2
Values 17 12
[48]
THLE PIK3C3
Mean 19.1
Standard deviation 0.92
Values 18 20
[49]
liver PIK3C3
Mean 10.1
Standard deviation 4.2
Values 6.9 15 6.8 11
[50]
ref_hepatocyte VAC14
Mean 4.46
Standard deviation 1.4
Values 3.8 2.9 6.2 5.7 3.7
[51]
HepG2 VAC14
Mean 25.3
Standard deviation 2.2
Values 27 24
[52]
HepG2.C3A VAC14
Mean 17.4
Standard deviation 0.12
Values 18 17
[53]
HuH.7 VAC14
Mean 25.7
Standard deviation 7.6
Values 34 18 25
[54]
SNU475 VAC14
Mean 11
Standard deviation 2
Values 12 9.6
[55]
THLE VAC14
Mean 28.2
Standard deviation 2.3
Values 27 30
[56]
liver VAC14
Mean 11.8
Standard deviation 3.3
Values 11 9.7 17 10
[57]
ref_hepatocyte PI4K2A
Mean 4.4
Standard deviation 2.7
Values 1.5 4 8.7 4.5 3.3
[58]
HepG2 PI4K2A
Mean 20.3
Standard deviation 2.2
Values 22 19
[59]
HepG2.C3A PI4K2A
Mean 21.9
Standard deviation 3.5
Values 24 19
[60]
HuH.7 PI4K2A
Mean 15.9
Standard deviation 2.3
Values 18 13 16
[61]
SNU475 PI4K2A
Mean 15.1
Standard deviation 1.6
Values 14 16
[62]
THLE PI4K2A
Mean 33.8
Standard deviation 4.8
Values 30 37
[63]
liver PI4K2A
Mean 9.81
Standard deviation 0.93
Values 8.6 9.6 11 10
[64]
ref_hepatocyte OCRL
Mean 2.8
Standard deviation 2.1
Values 6.4 2.6 1.7 1.7 1.6
[65]
HepG2 OCRL
Mean 25.8
Standard deviation 4.1
Values 23 29
[66]
HepG2.C3A OCRL
Mean 28.5
Standard deviation 3.8
Values 31 26
[67]
HuH.7 OCRL
Mean 38
Standard deviation 8.2
Values 36 47 31
[68]
SNU475 OCRL
Mean 27.1
Standard deviation 4.9
Values 31 24
[69]
THLE OCRL
Mean 28.8
Standard deviation 1
Values 28 29
[70]
liver OCRL
Mean 9.56
Standard deviation 3.8
Values 6.6 12 6.1 13
[71]
ref_hepatocyte PIK3C2A
Mean 2.52
Standard deviation 0.94
Values 3.9 2.7 2.4 1.4 2.2
[72]
HepG2 PIK3C2A
Mean 17.6
Standard deviation 8.6
Values 12 24
[73]
HepG2.C3A PIK3C2A
Mean 46.9
Standard deviation 9.1
Values 40 53
[74]
HuH.7 PIK3C2A
Mean 49.6
Standard deviation 15
Values 55 61 33
[75]
SNU475 PIK3C2A
Mean 38.5
Standard deviation 0.63
Values 39 38
[76]
THLE PIK3C2A
Mean 26.4
Standard deviation 7
Values 31 21
[77]
liver PIK3C2A
Mean 45.2
Standard deviation 21
Values 26 67 29 59
[78]
ref_hepatocyte PIK3R4
Mean 1.95
Standard deviation 0.81
Values 1.4 1.7 1.2 2.4 3.2
[79]
HepG2 PIK3R4
Mean 9.67
Standard deviation 3.2
Values 7.4 12
[80]
HepG2.C3A PIK3R4
Mean 8.97
Standard deviation 1.7
Values 7.8 10
[81]
HuH.7 PIK3R4
Mean 16.8
Standard deviation 2.8
Values 20 14 16
[82]
SNU475 PIK3R4
Mean 11.4
Standard deviation 0.1
Values 11 11
[83]
THLE PIK3R4
Mean 17.7
Standard deviation 1.3
Values 17 19
[84]
liver PIK3R4
Mean 20.3
Standard deviation 7.7
Values 15 27 12 27
[85]
ref_hepatocyte PIKFYVE
Mean 1.85
Standard deviation 1.2
Values 3.9 1.8 1.6 0.78 1.2
[86]
HepG2 PIKFYVE
Mean 9.2
Standard deviation 3.3
Values 6.9 12
[87]
HepG2.C3A PIKFYVE
Mean 25.9
Standard deviation 0.91
Values 25 27
[88]
HuH.7 PIKFYVE
Mean 53.6
Standard deviation 12
Values 60 61 40
[89]
SNU475 PIKFYVE
Mean 21.1
Standard deviation 3.8
Values 24 18
[90]
THLE PIKFYVE
Mean 22
Standard deviation 0.21
Values 22 22
[91]
liver PIKFYVE
Mean 27
Standard deviation 16
Values 15 40 12 41
[92]
ref_hepatocyte FIG4
Mean 1.71
Standard deviation 0.91
Values 1.9 3 0.54 1.9 1.3
[93]
HepG2 FIG4
Mean 5.9
Standard deviation 1.3
Values 5 6.8
[94]
HepG2.C3A FIG4
Mean 6.08
Standard deviation 0.039
Values 6.1 6
[95]
HuH.7 FIG4
Mean 5.7
Standard deviation 0.56
Values 5.9 5.1 6.1
[96]
SNU475 FIG4
Mean 6.63
Standard deviation 2.6
Values 8.5 4.8
[97]
THLE FIG4
Mean 6.84
Standard deviation 0.27
Values 6.6 7
[98]
liver FIG4
Mean 4.67
Standard deviation 1.1
Values 4.2 5.1 5.9 3.5
[99]
ref_hepatocyte INPP5E
Mean 1.35
Standard deviation 1.2
Values 0.55 0.9 3.6 0.84 0.88
[100]
HepG2 INPP5E
Mean 4.97
Standard deviation 1
Values 5.7 4.3
[101]
HepG2.C3A INPP5E
Mean 5
Standard deviation 0.96
Values 5.7 4.3
[102]
HuH.7 INPP5E
Mean 2.83
Standard deviation 0.63
Values 2.1 3 3.3
[103]
SNU475 INPP5E
Mean 5.54
Standard deviation 1.2
Values 6.4 4.7
[104]
THLE INPP5E
Mean 6.72
Standard deviation 0.25
Values 6.5 6.9
[105]
liver INPP5E
Mean 1.86
Standard deviation 0.52
Values 1.3 2.5 1.5 2.1
[106]
ref_hepatocyte PIK3C2G
Mean 1.1
Standard deviation 1.3
Values 0 0.41 0.15 2 3
[107]
HepG2 PIK3C2G
Mean 0.0093
Standard deviation 0.005
Values 0.0057 0.013
[108]
HepG2.C3A PIK3C2G
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 PIK3C2G
Mean 3.3
Standard deviation 2.2
Values 2.1 5.9 1.9
[110]
SNU475 PIK3C2G
Mean 0.199
Standard deviation 0.13
Values 0.29 0.11
[111]
THLE PIK3C2G
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[112]
liver PIK3C2G
Mean 32.6
Standard deviation 7.1
Values 36 35 22 37
[113]
ref_hepatocyte TPTE2
Mean 0.137
Standard deviation 0.2
Values 0 0 0.45 0 0.24
[114]
HepG2 TPTE2
Mean 0.0551
Standard deviation 0.013
Values 0.046 0.064
[115]
HepG2.C3A TPTE2
Mean 0.184
Standard deviation 0.12
Values 0.27 0.097
[116]
HuH.7 TPTE2
Mean 0.0751
Standard deviation 0.038
Values 0.09 0.032 0.1
[117]
SNU475 TPTE2
Mean 0.0819
Standard deviation 0.015
Values 0.093 0.071
[118]
THLE TPTE2
Mean 0.0476
Standard deviation 0.00039
Values 0.047 0.048
[119]
liver TPTE2
Mean 0.0161
Standard deviation 0.012
Values 0.024 0.014 0 0.026
[120]
ref_hepatocyte TPTE
Mean 0.0404
Standard deviation 0.038
Values 0 0.054 0.079 0.069 0
[121]
HepG2 TPTE
Mean 0
Standard deviation 0
Values 0 0
[122]
HepG2.C3A TPTE
Mean 0.0107
Standard deviation 0.015
Values 0 0.021
[123]
HuH.7 TPTE
Mean 1.96
Standard deviation 0.6
Values 1.7 1.6 2.6
[124]
SNU475 TPTE
Mean 0.709
Standard deviation 0.0068
Values 0.71 0.7
[125]
THLE TPTE
Mean 0.00887
Standard deviation 0.013
Values 0.018 0
[126]
liver TPTE
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0