REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PI4K2B Phosphatidylinositol 4-kinase type 2-beta [1] -0.93[2] -0.88[3] -0.44[4] -1.85[5] -2.11[6] -0.96[7]
2 MTMR4 Myotubularin-related protein 4 [8] -0.21[9] -0.12[10] 0.20[11] -1.74[12] -1.31[13] 0.56[14]
3 PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 [15] -0.47[16] -0.59[17] -1.55[18] -0.36[19] -0.35[20] -1.15[21]
4 VAC14 Protein VAC14 homolog [22] 0.51[23] -0.62[24] -0.04[25] -0.74[26] 0.25[27] -0.88[28]
5 PI4K2A Phosphatidylinositol 4-kinase type 2-alpha [29] 0.21[30] -0.26[31] -0.71[32] -0.27[33] 0.53[34] -1.13[35]
6 MTMR12 Myotubularin-related protein 12 [36] 0.49[37] 0.23[38] -1.17[39] -0.11[40] -0.22[41] -0.73[42]
7 MTM1 Myotubularin [43] -1.13[44] -0.58[45] -1.67[46] -1.50[47] -1.84[48] -0.62[49]
8 MTMR10 Myotubularin-related protein 10 [50] -1.11[51] -0.78[52] -0.92[53] -0.57[54] -1.10[55] 0.09[56]
9 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 0.81[57] 1.63[58] 1.74[59] 1.89[60] 0.98[61] 1.87[62]
10 MTMR2 Myotubularin-related protein 2 [63] 0.91[64] 0.84[65] -1.00[66] 1.66[67] 1.40[68] -1.33[69]
11 PIK3R4 Phosphoinositide 3-kinase regulatory subunit 4 [70] 0.31[71] -0.38[72] 0.54[73] 0.50[74] 0.77[75] 1.09[76]
12 PIKFYVE 1-phosphatidylinositol 3-phosphate 5-kinase [77] 0.32[78] 1.22[79] 2.30[80] 1.47[81] 1.16[82] 1.57[83]
13 FIG4 Polyphosphoinositide phosphatase [84] -0.21[85] -0.75[86] -0.82[87] -0.09[88] -0.41[89] -0.84[90]
14 INPP5F Phosphatidylinositide phosphatase SAC2 [91] -0.03[92] 0.95[93] -1.71[94] -0.22[95] 1.16[96] -1.72[97]
15 INPP4A Type I inositol 3,4-bisphosphate 4-phosphatase [98] 1.51[99] 0.79[100] 1.41[101] 2.36[102] 1.86[103] 1.21[104]
16 INPP4B Type II inositol 3,4-bisphosphate 4-phosphatase [105] -0.76[106] -2.45[107] [108] 0.65[109] 7.61[110] 6.22[111]
[1]
ref_hepatocyte PI4K2B
Mean 9.12
Standard deviation 4.6
Values 13 9.2 4.5 4.4 14
[2]
HepG2 PI4K2B
Mean 19.1
Standard deviation 9.8
Values 12 26
[3]
HepG2.C3A PI4K2B
Mean 29.6
Standard deviation 12
Values 21 38
[4]
HuH.7 PI4K2B
Mean 39.8
Standard deviation 4
Values 43 36 40
[5]
SNU475 PI4K2B
Mean 10.5
Standard deviation 2.4
Values 12 8.7
[6]
THLE PI4K2B
Mean 11.2
Standard deviation 3
Values 9.1 13
[7]
liver PI4K2B
Mean 23
Standard deviation 5.7
Values 21 29 16 26
[8]
ref_hepatocyte MTMR4
Mean 6.86
Standard deviation 3.5
Values 11 5.3 2 6.5 9.8
[9]
HepG2 MTMR4
Mean 23.6
Standard deviation 2.3
Values 22 25
[10]
HepG2.C3A MTMR4
Mean 37.9
Standard deviation 2.1
Values 39 36
[11]
HuH.7 MTMR4
Mean 46.4
Standard deviation 18
Values 38 67 34
[12]
SNU475 MTMR4
Mean 8.44
Standard deviation 2.5
Values 10 6.7
[13]
THLE MTMR4
Mean 14.7
Standard deviation 0.29
Values 14 15
[14]
liver MTMR4
Mean 49.4
Standard deviation 19
Values 29 70 37 61
[15]
ref_hepatocyte PIK3C3
Mean 4.59
Standard deviation 2.3
Values 8 5.9 2.3 3.8 3
[16]
HepG2 PIK3C3
Mean 13.2
Standard deviation 3.3
Values 11 16
[17]
HepG2.C3A PIK3C3
Mean 18.2
Standard deviation 1.3
Values 17 19
[18]
HuH.7 PIK3C3
Mean 9.26
Standard deviation 1.9
Values 9.1 11 7.5
[19]
SNU475 PIK3C3
Mean 14.7
Standard deviation 3.2
Values 17 12
[20]
THLE PIK3C3
Mean 19.1
Standard deviation 0.92
Values 18 20
[21]
liver PIK3C3
Mean 10.1
Standard deviation 4.2
Values 6.9 15 6.8 11
[22]
ref_hepatocyte VAC14
Mean 4.46
Standard deviation 1.4
Values 3.8 2.9 6.2 5.7 3.7
[23]
HepG2 VAC14
Mean 25.3
Standard deviation 2.2
Values 27 24
[24]
HepG2.C3A VAC14
Mean 17.4
Standard deviation 0.12
Values 18 17
[25]
HuH.7 VAC14
Mean 25.7
Standard deviation 7.6
Values 34 18 25
[26]
SNU475 VAC14
Mean 11
Standard deviation 2
Values 12 9.6
[27]
THLE VAC14
Mean 28.2
Standard deviation 2.3
Values 27 30
[28]
liver VAC14
Mean 11.8
Standard deviation 3.3
Values 11 9.7 17 10
[29]
ref_hepatocyte PI4K2A
Mean 4.4
Standard deviation 2.7
Values 1.5 4 8.7 4.5 3.3
[30]
HepG2 PI4K2A
Mean 20.3
Standard deviation 2.2
Values 22 19
[31]
HepG2.C3A PI4K2A
Mean 21.9
Standard deviation 3.5
Values 24 19
[32]
HuH.7 PI4K2A
Mean 15.9
Standard deviation 2.3
Values 18 13 16
[33]
SNU475 PI4K2A
Mean 15.1
Standard deviation 1.6
Values 14 16
[34]
THLE PI4K2A
Mean 33.8
Standard deviation 4.8
Values 30 37
[35]
liver PI4K2A
Mean 9.81
Standard deviation 0.93
Values 8.6 9.6 11 10
[36]
ref_hepatocyte MTMR12
Mean 4.08
Standard deviation 2.1
Values 7.5 4.3 3.5 2 3.1
[37]
HepG2 MTMR12
Mean 22.8
Standard deviation 4.1
Values 20 26
[38]
HepG2.C3A MTMR12
Mean 28.7
Standard deviation 0.61
Values 28 29
[39]
HuH.7 MTMR12
Mean 10.7
Standard deviation 2.2
Values 13 8.7 10
[40]
SNU475 MTMR12
Mean 15.6
Standard deviation 0.45
Values 15 16
[41]
THLE MTMR12
Mean 18.6
Standard deviation 0.48
Values 19 18
[42]
liver MTMR12
Mean 12
Standard deviation 5.7
Values 8.9 16 5.6 18
[43]
ref_hepatocyte MTM1
Mean 3.45
Standard deviation 2
Values 6.4 1.8 2.2 2.3 4.6
[44]
HepG2 MTM1
Mean 6.28
Standard deviation 2.9
Values 4.2 8.4
[45]
HepG2.C3A MTM1
Mean 13.9
Standard deviation 2.9
Values 12 16
[46]
HuH.7 MTM1
Mean 6.39
Standard deviation 0.87
Values 7.2 5.5 6.5
[47]
SNU475 MTM1
Mean 5.05
Standard deviation 0.37
Values 5.3 4.8
[48]
THLE MTM1
Mean 5.14
Standard deviation 0.006
Values 5.1 5.1
[49]
liver MTM1
Mean 11
Standard deviation 1
Values 11 11 12 9.8
[50]
ref_hepatocyte MTMR10
Mean 3.24
Standard deviation 1.3
Values 3.4 2.3 1.9 3.4 5.2
[51]
HepG2 MTMR10
Mean 5.98
Standard deviation 2.4
Values 4.3 7.7
[52]
HepG2.C3A MTMR10
Mean 11.3
Standard deviation 0.69
Values 11 12
[53]
HuH.7 MTMR10
Mean 10.1
Standard deviation 2.3
Values 10 12 7.8
[54]
SNU475 MTMR10
Mean 9.04
Standard deviation 2.3
Values 11 7.4
[55]
THLE MTMR10
Mean 8.07
Standard deviation 0.76
Values 7.5 8.6
[56]
liver MTMR10
Mean 16.9
Standard deviation 2.6
Values 15 20 15 18
[57]
ref_hepatocyte PIK3C2A
Mean 2.52
Standard deviation 0.94
Values 3.9 2.7 2.4 1.4 2.2
[58]
HepG2 PIK3C2A
Mean 17.6
Standard deviation 8.6
Values 12 24
[59]
HepG2.C3A PIK3C2A
Mean 46.9
Standard deviation 9.1
Values 40 53
[60]
HuH.7 PIK3C2A
Mean 49.6
Standard deviation 15
Values 55 61 33
[61]
SNU475 PIK3C2A
Mean 38.5
Standard deviation 0.63
Values 39 38
[62]
THLE PIK3C2A
Mean 26.4
Standard deviation 7
Values 31 21
[63]
liver PIK3C2A
Mean 45.2
Standard deviation 21
Values 26 67 29 59
[64]
ref_hepatocyte MTMR2
Mean 2.23
Standard deviation 1.7
Values 4.3 3.8 1.7 0.64 0.76
[65]
HepG2 MTMR2
Mean 16.6
Standard deviation 3.5
Values 14 19
[66]
HepG2.C3A MTMR2
Mean 23.9
Standard deviation 7
Values 19 29
[67]
HuH.7 MTMR2
Mean 6.56
Standard deviation 0.94
Values 7.5 5.7 6.4
[68]
SNU475 MTMR2
Mean 29.1
Standard deviation 1.7
Values 30 28
[69]
THLE MTMR2
Mean 31.2
Standard deviation 3
Values 29 33
[70]
liver MTMR2
Mean 4.35
Standard deviation 0.41
Values 3.9 4.5 4.8 4.2
[71]
ref_hepatocyte PIK3R4
Mean 1.95
Standard deviation 0.81
Values 1.4 1.7 1.2 2.4 3.2
[72]
HepG2 PIK3R4
Mean 9.67
Standard deviation 3.2
Values 7.4 12
[73]
HepG2.C3A PIK3R4
Mean 8.97
Standard deviation 1.7
Values 7.8 10
[74]
HuH.7 PIK3R4
Mean 16.8
Standard deviation 2.8
Values 20 14 16
[75]
SNU475 PIK3R4
Mean 11.4
Standard deviation 0.1
Values 11 11
[76]
THLE PIK3R4
Mean 17.7
Standard deviation 1.3
Values 17 19
[77]
liver PIK3R4
Mean 20.3
Standard deviation 7.7
Values 15 27 12 27
[78]
ref_hepatocyte PIKFYVE
Mean 1.85
Standard deviation 1.2
Values 3.9 1.8 1.6 0.78 1.2
[79]
HepG2 PIKFYVE
Mean 9.2
Standard deviation 3.3
Values 6.9 12
[80]
HepG2.C3A PIKFYVE
Mean 25.9
Standard deviation 0.91
Values 25 27
[81]
HuH.7 PIKFYVE
Mean 53.6
Standard deviation 12
Values 60 61 40
[82]
SNU475 PIKFYVE
Mean 21.1
Standard deviation 3.8
Values 24 18
[83]
THLE PIKFYVE
Mean 22
Standard deviation 0.21
Values 22 22
[84]
liver PIKFYVE
Mean 27
Standard deviation 16
Values 15 40 12 41
[85]
ref_hepatocyte FIG4
Mean 1.71
Standard deviation 0.91
Values 1.9 3 0.54 1.9 1.3
[86]
HepG2 FIG4
Mean 5.9
Standard deviation 1.3
Values 5 6.8
[87]
HepG2.C3A FIG4
Mean 6.08
Standard deviation 0.039
Values 6.1 6
[88]
HuH.7 FIG4
Mean 5.7
Standard deviation 0.56
Values 5.9 5.1 6.1
[89]
SNU475 FIG4
Mean 6.63
Standard deviation 2.6
Values 8.5 4.8
[90]
THLE FIG4
Mean 6.84
Standard deviation 0.27
Values 6.6 7
[91]
liver FIG4
Mean 4.67
Standard deviation 1.1
Values 4.2 5.1 5.9 3.5
[92]
ref_hepatocyte INPP5F
Mean 1.49
Standard deviation 1.5
Values 3.9 0.9 1.8 0.59 0.24
[93]
HepG2 INPP5F
Mean 5.83
Standard deviation 1.4
Values 4.8 6.8
[94]
HepG2.C3A INPP5F
Mean 17.3
Standard deviation 1.2
Values 16 18
[95]
HuH.7 INPP5F
Mean 2.69
Standard deviation 0.09
Values 2.8 2.6 2.7
[96]
SNU475 INPP5F
Mean 5.27
Standard deviation 0.33
Values 5 5.5
[97]
THLE INPP5F
Mean 17.7
Standard deviation 2.1
Values 19 16
[98]
liver INPP5F
Mean 2.21
Standard deviation 0.73
Values 2 3.1 1.3 2.4
[99]
ref_hepatocyte INPP4A
Mean 0.757
Standard deviation 0.47
Values 1.5 0.91 0.3 0.38 0.74
[100]
HepG2 INPP4A
Mean 8.61
Standard deviation 0.94
Values 7.9 9.3
[101]
HepG2.C3A INPP4A
Mean 7.83
Standard deviation 0.93
Values 8.5 7.2
[102]
HuH.7 INPP4A
Mean 11.9
Standard deviation 2.1
Values 14 11 11
[103]
SNU475 INPP4A
Mean 16.1
Standard deviation 5.3
Values 20 12
[104]
THLE INPP4A
Mean 14.6
Standard deviation 0.67
Values 15 14
[105]
liver INPP4A
Mean 8.57
Standard deviation 2.8
Values 5.9 12 6.5 10
[106]
ref_hepatocyte INPP4B
Mean 0.00488
Standard deviation 0.011
Values 0 0 0 0 0.024
[107]
HepG2 INPP4B
Mean 0.0114
Standard deviation 0.0081
Values 0.0057 0.017
[108]
HepG2.C3A INPP4B
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[109]
HuH.7 INPP4B
Mean 0
Standard deviation 0
Values 0 0 0
[110]
SNU475 INPP4B
Mean 0.0317
Standard deviation 0.0054
Values 0.028 0.035
[111]
THLE INPP4B
Mean 5.09
Standard deviation 0.62
Values 4.6 5.5
[112]
liver INPP4B
Mean 1.78
Standard deviation 1.2
Values 0.71 3.2 0.8 2.5