REACTOME_SYNTHESIS_OF_IP2_IP_AND_INS_IN_THE_CYTOSOL Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 IMPA2 Inositol monophosphatase 2 [1] -1.86[2] -1.25[3] -0.47[4] -1.01[5] -3.29[6] -1.28[7]
2 INPP5A Type I inositol 1,4,5-trisphosphate 5-phosphatase [8] -0.16[9] -0.38[10] -1.49[11] -2.11[12] -1.71[13] -1.32[14]
3 INPP1 Inositol polyphosphate 1-phosphatase [15] -1.61[16] -0.55[17] -1.00[18] -2.00[19] -0.64[20] -1.31[21]
4 IMPA1 Inositol monophosphatase 1 [22] -0.36[23] 0.07[24] -0.15[25] 0.96[26] 0.56[27] 0.91[28]
5 OCRL Inositol polyphosphate 5-phosphatase OCRL-1 [29] 1.62[30] 1.29[31] 1.71[32] 2.04[33] 1.91[34] 0.62[35]
6 INPP5B Type II inositol 1,4,5-trisphosphate 5-phosphatase [36] 0.22[37] -0.29[38] -0.12[39] -0.51[40] 0.73[41] 1.96[42]
7 ISYNA1 Inositol-3-phosphate synthase 1 [43] 2.98[44] 2.56[45] 1.86[46] -2.60[47] 1.14[48] 0.20[49]
8 MTMR9 Myotubularin-related protein 9 [50] 0.56[51] 0.37[52] 0.11[53] 0.88[54] 1.88[55] 2.23[56]
9 INPP4A Type I inositol 3,4-bisphosphate 4-phosphatase [57] 1.92[58] 1.31[59] 1.91[60] 3.17[61] 2.82[62] 2.35[63]
10 SYNJ1 Synaptojanin-1 [64] 0.95[65] 0.65[66] 1.24[67] 2.78[68] 2.86[69] 2.66[70]
11 MTMR7 Myotubularin-related protein 7 [71] 0.50[72] 2.12[73] 2.75[74] 1.39[75] 1.37[76] 2.61[77]
12 INPP5J Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A [78] 3.42[79] 0.62[80] 4.14[81] 2.95[82] 4.38[83] -1.09[84]
13 INPP4B Type II inositol 3,4-bisphosphate 4-phosphatase [85] -0.36[86] -1.92[87] [88] 1.46[89] 8.57[90] 7.36[91]
14 MIOX Inositol oxygenase [92] [93] [94] [95] [96] [97] [98]
[1]
ref_hepatocyte IMPA2
Mean 19
Standard deviation 10
Values 27 9.1 7.1 25 28
[2]
HepG2 IMPA2
Mean 15.8
Standard deviation 3.8
Values 18 13
[3]
HepG2.C3A IMPA2
Mean 33.4
Standard deviation 5.2
Values 30 37
[4]
HuH.7 IMPA2
Mean 57
Standard deviation 21
Values 61 34 75
[5]
SNU475 IMPA2
Mean 22.3
Standard deviation 2.6
Values 24 21
[6]
THLE IMPA2
Mean 5.3
Standard deviation 0.48
Values 5.6 5
[7]
liver IMPA2
Mean 17.4
Standard deviation 6.3
Values 24 11 21 13
[8]
ref_hepatocyte INPP5A
Mean 7.74
Standard deviation 7.8
Values 21 8.6 1.6 3.5 4.1
[9]
HepG2 INPP5A
Mean 20.9
Standard deviation 4
Values 18 24
[10]
HepG2.C3A INPP5A
Mean 24.8
Standard deviation 3
Values 23 27
[11]
HuH.7 INPP5A
Mean 11.5
Standard deviation 0.85
Values 12 11 11
[12]
SNU475 INPP5A
Mean 4.22
Standard deviation 0.61
Values 4.7 3.8
[13]
THLE INPP5A
Mean 6.45
Standard deviation 0.31
Values 6.2 6.7
[14]
liver INPP5A
Mean 6.89
Standard deviation 2.6
Values 7 7.9 3.3 9.4
[15]
ref_hepatocyte INPP1
Mean 6.49
Standard deviation 3.7
Values 1.2 8.5 10 8.5 4.2
[16]
HepG2 INPP1
Mean 6.42
Standard deviation 0.55
Values 6.8 6
[17]
HepG2.C3A INPP1
Mean 18.5
Standard deviation 2.7
Values 20 17
[18]
HuH.7 INPP1
Mean 13.5
Standard deviation 1.7
Values 14 12 15
[19]
SNU475 INPP1
Mean 3.83
Standard deviation 0.24
Values 3.7 4
[20]
THLE INPP1
Mean 11.4
Standard deviation 0.22
Values 11 12
[21]
liver INPP1
Mean 5.8
Standard deviation 3.5
Values 9.7 2.7 7.9 2.9
[22]
ref_hepatocyte IMPA1
Mean 3.72
Standard deviation 1.7
Values 3.6 6.6 2.4 2.5 3.4
[23]
HepG2 IMPA1
Mean 8.73
Standard deviation 3.4
Values 6.3 11
[24]
HepG2.C3A IMPA1
Mean 16.3
Standard deviation 4.4
Values 13 19
[25]
HuH.7 IMPA1
Mean 13.9
Standard deviation 1.9
Values 14 12 16
[26]
SNU475 IMPA1
Mean 17.1
Standard deviation 2.7
Values 19 15
[27]
THLE IMPA1
Mean 15
Standard deviation 2
Values 14 16
[28]
liver IMPA1
Mean 15.5
Standard deviation 2.5
Values 18 15 12 17
[29]
ref_hepatocyte OCRL
Mean 2.8
Standard deviation 2.1
Values 6.4 2.6 1.7 1.7 1.6
[30]
HepG2 OCRL
Mean 25.8
Standard deviation 4.1
Values 23 29
[31]
HepG2.C3A OCRL
Mean 28.5
Standard deviation 3.8
Values 31 26
[32]
HuH.7 OCRL
Mean 38
Standard deviation 8.2
Values 36 47 31
[33]
SNU475 OCRL
Mean 27.1
Standard deviation 4.9
Values 31 24
[34]
THLE OCRL
Mean 28.8
Standard deviation 1
Values 28 29
[35]
liver OCRL
Mean 9.56
Standard deviation 3.8
Values 6.6 12 6.1 13
[36]
ref_hepatocyte INPP5B
Mean 1.53
Standard deviation 0.74
Values 1.6 1.1 0.51 2.2 2.2
[37]
HepG2 INPP5B
Mean 5.37
Standard deviation 0.56
Values 5.8 5
[38]
HepG2.C3A INPP5B
Mean 5.2
Standard deviation 0.98
Values 5.9 4.5
[39]
HuH.7 INPP5B
Mean 5.83
Standard deviation 1.5
Values 5.5 4.5 7.5
[40]
SNU475 INPP5B
Mean 2.53
Standard deviation 0.2
Values 2.4 2.7
[41]
THLE INPP5B
Mean 6.92
Standard deviation 0.46
Values 6.6 7.2
[42]
liver INPP5B
Mean 13.1
Standard deviation 2.2
Values 13 16 10 13
[43]
ref_hepatocyte ISYNA1
Mean 1.44
Standard deviation 2
Values 5 0.36 0.64 0.62 0.55
[44]
HepG2 ISYNA1
Mean 34.3
Standard deviation 13
Values 44 25
[45]
HepG2.C3A ISYNA1
Mean 35.5
Standard deviation 8.3
Values 41 30
[46]
HuH.7 ISYNA1
Mean 21.8
Standard deviation 7.2
Values 26 14 26
[47]
SNU475 ISYNA1
Mean 0.563
Standard deviation 0.022
Values 0.55 0.58
[48]
THLE ISYNA1
Mean 8.72
Standard deviation 1.7
Values 9.9 7.5
[49]
liver ISYNA1
Mean 3.68
Standard deviation 3.1
Values 8.2 1.1 2.9 2.5
[50]
ref_hepatocyte MTMR9
Mean 0.96
Standard deviation 0.48
Values 0.85 1.7 1.1 0.59 0.54
[51]
HepG2 MTMR9
Mean 4.28
Standard deviation 0.48
Values 3.9 4.6
[52]
HepG2.C3A MTMR9
Mean 5.16
Standard deviation 0.36
Values 4.9 5.4
[53]
HuH.7 MTMR9
Mean 4.3
Standard deviation 0.84
Values 5.3 3.8 3.9
[54]
SNU475 MTMR9
Mean 4.17
Standard deviation 0.23
Values 4.3 4
[55]
THLE MTMR9
Mean 9.65
Standard deviation 0.37
Values 9.9 9.4
[56]
liver MTMR9
Mean 10
Standard deviation 3.7
Values 6.9 14 7 12
[57]
ref_hepatocyte INPP4A
Mean 0.757
Standard deviation 0.47
Values 1.5 0.91 0.3 0.38 0.74
[58]
HepG2 INPP4A
Mean 8.61
Standard deviation 0.94
Values 7.9 9.3
[59]
HepG2.C3A INPP4A
Mean 7.83
Standard deviation 0.93
Values 8.5 7.2
[60]
HuH.7 INPP4A
Mean 11.9
Standard deviation 2.1
Values 14 11 11
[61]
SNU475 INPP4A
Mean 16.1
Standard deviation 5.3
Values 20 12
[62]
THLE INPP4A
Mean 14.6
Standard deviation 0.67
Values 15 14
[63]
liver INPP4A
Mean 8.57
Standard deviation 2.8
Values 5.9 12 6.5 10
[64]
ref_hepatocyte SYNJ1
Mean 0.438
Standard deviation 0.073
Values 0.45 0.45 0.38 0.36 0.54
[65]
HepG2 SYNJ1
Mean 2.55
Standard deviation 1.1
Values 1.8 3.3
[66]
HepG2.C3A SYNJ1
Mean 2.86
Standard deviation 0.44
Values 2.5 3.2
[67]
HuH.7 SYNJ1
Mean 4.3
Standard deviation 0.6
Values 4.8 4.5 3.6
[68]
SNU475 SYNJ1
Mean 7.11
Standard deviation 0.46
Values 6.8 7.4
[69]
THLE SYNJ1
Mean 8.68
Standard deviation 0.99
Values 8 9.4
[70]
liver SYNJ1
Mean 6.13
Standard deviation 1.1
Values 5.7 7.8 5.2 5.9
[71]
ref_hepatocyte MTMR7
Mean 0.103
Standard deviation 0.13
Values 0 0 0.32 0.1 0.098
[72]
HepG2 MTMR7
Mean 0.439
Standard deviation 0.07
Values 0.39 0.49
[73]
HepG2.C3A MTMR7
Mean 1.86
Standard deviation 0.4
Values 2.1 1.6
[74]
HuH.7 MTMR7
Mean 2.89
Standard deviation 0.92
Values 2.3 3.9 2.5
[75]
SNU475 MTMR7
Mean 0.637
Standard deviation 0.074
Values 0.58 0.69
[76]
THLE MTMR7
Mean 0.729
Standard deviation 0.25
Values 0.91 0.55
[77]
liver MTMR7
Mean 1.4
Standard deviation 0.5
Values 1.1 1.7 0.9 1.9
[78]
ref_hepatocyte INPP5J
Mean 0.0311
Standard deviation 0.07
Values 0 0.16 0 0 0
[79]
HepG2 INPP5J
Mean 1
Standard deviation 0.062
Values 1 0.96
[80]
HepG2.C3A INPP5J
Mean 0.199
Standard deviation 0.14
Values 0.3 0.097
[81]
HuH.7 INPP5J
Mean 2.29
Standard deviation 1.3
Values 1.3 3.8 1.8
[82]
SNU475 INPP5J
Mean 0.567
Standard deviation 0.24
Values 0.39 0.74
[83]
THLE INPP5J
Mean 1.76
Standard deviation 0.51
Values 2.1 1.4
[84]
liver INPP5J
Mean 0.0323
Standard deviation 0.05
Values 0.024 0 0 0.11
[85]
ref_hepatocyte INPP4B
Mean 0.00488
Standard deviation 0.011
Values 0 0 0 0 0.024
[86]
HepG2 INPP4B
Mean 0.0114
Standard deviation 0.0081
Values 0.0057 0.017
[87]
HepG2.C3A INPP4B
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[88]
HuH.7 INPP4B
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 INPP4B
Mean 0.0317
Standard deviation 0.0054
Values 0.028 0.035
[90]
THLE INPP4B
Mean 5.09
Standard deviation 0.62
Values 4.6 5.5
[91]
liver INPP4B
Mean 1.78
Standard deviation 1.2
Values 0.71 3.2 0.8 2.5
[92]
ref_hepatocyte MIOX
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 MIOX
Mean 1.46
Standard deviation 0.12
Values 1.5 1.4
[94]
HepG2.C3A MIOX
Mean 7.26
Standard deviation 1.9
Values 8.6 5.9
[95]
HuH.7 MIOX
Mean 0.267
Standard deviation 0.11
Values 0.15 0.31 0.35
[96]
SNU475 MIOX
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[97]
THLE MIOX
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[98]
liver MIOX
Mean 0.00642
Standard deviation 0.013
Values 0 0 0.026 0