REACTOME_SYNTHESIS_OF_EPOXY_EET_AND_DIHYDROXYEICOSATRIENOIC_ACIDS_DHET Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CYP2C8 Cytochrome P450 2C8 [1] -9.37[2] -5.76[3] -5.39[4] -7.04[5] [6] -0.08[7]
2 CYP2C9 Cytochrome P450 2C9 [8] [9] -10.68[10] -5.61[11] -9.73[12] -11.28[13] 0.43[14]
3 CYP1A2 Cytochrome P450 1A2 [15] -3.80[16] -3.63[17] -6.12[18] -3.61[19] -6.39[20] -2.24[21]
4 CYP1A1 Cytochrome P450 1A1 [22] 2.66[23] -0.06[24] 1.77[25] 0.99[26] -1.91[27] -6.39[28]
5 EPHX2 Bifunctional epoxide hydrolase 2 [29] 3.84[30] 4.52[31] 4.13[32] 0.61[33] -1.51[34] 0.35[35]
6 CYP2J2 Cytochrome P450 2J2 [36] 1.72[37] 0.59[38] 1.88[39] -1.71[40] -2.60[41] -0.32[42]
7 CYP2C19 Cytochrome P450 2C19 [43] [44] [45] -2.75[46] -7.42[47] -9.59[48] 0.99[49]
8 CYP1B1 Cytochrome P450 1B1 [50] 0.07[51] -0.49[52] 1.79[53] 7.98[54] 8.23[55] 0.42[56]
[1]
ref_hepatocyte CYP2C8
Mean 328
Standard deviation 4.4e+02
Values 0 1.2 19 7.1e+02 9.1e+02
[2]
HepG2 CYP2C8
Mean 0.00788
Standard deviation 0.0051
Values 0.011 0.0043
[3]
HepG2.C3A CYP2C8
Mean 0.186
Standard deviation 0.071
Values 0.14 0.24
[4]
HuH.7 CYP2C8
Mean 0.822
Standard deviation 1
Values 0.16 2 0.3
[5]
SNU475 CYP2C8
Mean 0.0515
Standard deviation 0.02
Values 0.037 0.066
[6]
THLE CYP2C8
Mean 0
Standard deviation 0
Values 0 0
[7]
liver CYP2C8
Mean 666
Standard deviation 3.9e+02
Values 6.8e+02 6.2e+02 1.2e+03 2e+02
[8]
ref_hepatocyte CYP2C9
Mean 285
Standard deviation 4.1e+02
Values 0.064 20 21 4.7e+02 9.2e+02
[9]
HepG2 CYP2C9
Mean 0
Standard deviation 0
Values 0 0
[10]
HepG2.C3A CYP2C9
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[11]
HuH.7 CYP2C9
Mean 0.616
Standard deviation 0.63
Values 0.25 1.3 0.25
[12]
SNU475 CYP2C9
Mean 0.00696
Standard deviation 0.0098
Values 0.014 0
[13]
THLE CYP2C9
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[14]
liver CYP2C9
Mean 822
Standard deviation 5.3e+02
Values 8.6e+02 6.1e+02 1.5e+03 2.9e+02
[15]
ref_hepatocyte CYP1A2
Mean 78.9
Standard deviation 1.3e+02
Values 0.4 18 0.97 71 3e+02
[16]
HepG2 CYP1A2
Mean 0.0901
Standard deviation 0.055
Values 0.052 0.13
[17]
HepG2.C3A CYP1A2
Mean 0.197
Standard deviation 0.066
Values 0.24 0.15
[18]
HuH.7 CYP1A2
Mean 0.12
Standard deviation 0.026
Values 0.11 0.1 0.15
[19]
SNU475 CYP1A2
Mean 0.134
Standard deviation 0.091
Values 0.07 0.2
[20]
THLE CYP1A2
Mean 0.112
Standard deviation 0.068
Values 0.16 0.064
[21]
liver CYP1A2
Mean 35.7
Standard deviation 24
Values 55 12 58 19
[22]
ref_hepatocyte CYP1A1
Mean 43.8
Standard deviation 36
Values 77 43 0.06 17 82
[23]
HepG2 CYP1A1
Mean 4.39
Standard deviation 2.6
Values 6.2 2.6
[24]
HepG2.C3A CYP1A1
Mean 1.3
Standard deviation 0.1
Values 1.4 1.2
[25]
HuH.7 CYP1A1
Mean 15.8
Standard deviation 1.4
Values 14 17 17
[26]
SNU475 CYP1A1
Mean 1.8
Standard deviation 1.8
Values 0.49 3.1
[27]
THLE CYP1A1
Mean 1.38
Standard deviation 0.04
Values 1.4 1.4
[28]
liver CYP1A1
Mean 1.12
Standard deviation 0.58
Values 1.2 0.47 0.92 1.8
[29]
ref_hepatocyte EPHX2
Mean 31.5
Standard deviation 40
Values 6.6 5.1 2.2 51 93
[30]
HepG2 EPHX2
Mean 7.16
Standard deviation 2
Values 5.8 8.5
[31]
HepG2.C3A EPHX2
Mean 22.2
Standard deviation 4
Values 25 19
[32]
HuH.7 EPHX2
Mean 58
Standard deviation 2.7
Values 58 55 61
[33]
SNU475 EPHX2
Mean 0.995
Standard deviation 0.55
Values 1.4 0.61
[34]
THLE EPHX2
Mean 1.31
Standard deviation 0.13
Values 1.4 1.2
[35]
liver EPHX2
Mean 85.8
Standard deviation 57
Values 1.6e+02 42 1e+02 40
[36]
ref_hepatocyte CYP2J2
Mean 23.2
Standard deviation 23
Values 1.9 9.2 9.9 44 51
[37]
HepG2 CYP2J2
Mean 1.21
Standard deviation 0.23
Values 1.4 1
[38]
HepG2.C3A CYP2J2
Mean 1.08
Standard deviation 0.51
Values 1.4 0.72
[39]
HuH.7 CYP2J2
Mean 8.98
Standard deviation 0.32
Values 8.6 9 9.3
[40]
SNU475 CYP2J2
Mean 0.147
Standard deviation 0.13
Values 0.056 0.24
[41]
THLE CYP2J2
Mean 0.454
Standard deviation 0.094
Values 0.52 0.39
[42]
liver CYP2J2
Mean 39.7
Standard deviation 21
Values 66 21 48 24
[43]
ref_hepatocyte CYP2C19
Mean 19.2
Standard deviation 30
Values 0 5.9 0 18 72
[44]
HepG2 CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[45]
HepG2.C3A CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 CYP2C19
Mean 0.3
Standard deviation 0.27
Values 0.098 0.6 0.2
[47]
SNU475 CYP2C19
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[48]
THLE CYP2C19
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[49]
liver CYP2C19
Mean 81.4
Standard deviation 39
Values 65 92 1.3e+02 38
[50]
ref_hepatocyte CYP1B1
Mean 2.62
Standard deviation 3.2
Values 0.024 8 0.92 2.7 1.4
[51]
HepG2 CYP1B1
Mean 0.0437
Standard deviation 0.019
Values 0.057 0.03
[52]
HepG2.C3A CYP1B1
Mean 0.0575
Standard deviation 0.04
Values 0.029 0.086
[53]
HuH.7 CYP1B1
Mean 0.95
Standard deviation 0.082
Values 0.87 1 0.95
[54]
SNU475 CYP1B1
Mean 13.6
Standard deviation 3.1
Values 16 11
[55]
THLE CYP1B1
Mean 93
Standard deviation 14
Values 1e+02 83
[56]
liver CYP1B1
Mean 7.5
Standard deviation 1.4
Values 6.9 7.4 9.5 6.2