REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 AKR1C1 Aldo-keto reductase family 1 member C1 [1] -0.48[2] -0.87[3] -3.87[4] -1.18[5] -4.01[6] -3.88[7]
2 AKR1C3 Aldo-keto reductase family 1 member C3 [8] 0.01[9] 0.56[10] -5.37[11] 2.07[12] -3.05[13] -1.84[14]
3 SCP2 Non-specific lipid-transfer protein [15] -1.56[16] -0.50[17] 0.46[18] -1.75[19] 0.06[20] 0.69[21]
4 AKR1C2 Aldo-keto reductase family 1 member C2 [22] 1.39[23] -0.72[24] -2.65[25] 1.17[26] -2.82[27] -0.81[28]
5 CYP27A1 Sterol 26-hydroxylase, mitochondrial [29] 0.20[30] 0.92[31] -1.47[32] -2.87[33] -2.47[34] 0.44[35]
6 AKR1C4 Aldo-keto reductase family 1 member C4 [36] -6.79[37] -4.49[38] -4.37[39] -8.99[40] -12.51[41] -0.53[42]
7 HSD17B4 Peroxisomal multifunctional enzyme type 2 [43] 0.84[44] 1.14[45] 1.58[46] -0.31[47] 2.31[48] 1.12[49]
8 SLC27A5 Bile acyl-CoA synthetase [50] -3.16[51] -1.99[52] -2.88[53] -5.80[54] -6.35[55] 0.98[56]
9 SLC27A2 Very long-chain acyl-CoA synthetase [57] -1.26[58] -1.16[59] -0.72[60] -2.39[61] -4.35[62] 1.51[63]
10 BAAT Bile acid-CoA:amino acid N-acyltransferase [64] -3.24[65] -2.69[66] -4.34[67] -6.57[68] -5.93[69] 2.10[70]
11 CYP8B1 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase [71] -5.94[72] -3.47[73] -6.69[74] -8.30[75] -8.17[76] 2.80[77]
12 HSD3B7 3 beta-hydroxysteroid dehydrogenase type 7 [78] 1.05[79] 1.83[80] -0.59[81] -1.78[82] -0.22[83] 0.69[84]
13 AKR1D1 3-oxo-5-beta-steroid 4-dehydrogenase [85] -0.80[86] 0.50[87] -1.50[88] -8.43[89] -6.70[90] 0.08[91]
14 OSBPL9 Oxysterol-binding protein-related protein 9 [92] 2.28[93] 2.64[94] 3.39[95] 2.31[96] 3.87[97] 1.15[98]
15 NR1H4 Bile acid receptor [99] 0.68[100] 1.20[101] 3.69[102] -6.37[103] -4.44[104] 0.87[105]
16 ACOX2 Peroxisomal acyl-coenzyme A oxidase 2 [106] -0.14[107] 1.12[108] 1.56[109] -6.19[110] -1.91[111] 1.48[112]
17 RXRA Retinoic acid receptor RXR-alpha [113] 2.22[114] 1.96[115] 3.50[116] 1.69[117] 3.32[118] 2.50[119]
18 OSBP Oxysterol-binding protein 1 [120] 2.47[121] 2.59[122] 4.82[123] 2.15[124] 3.97[125] 2.18[126]
19 AMACR Alpha-methylacyl-CoA racemase [127] -1.58[128] -1.64[129] 0.52[130] -2.90[131] -1.36[132] -1.47[133]
20 ACOT8 Acyl-coenzyme A thioesterase 8 [134] 1.34[135] 1.74[136] 2.49[137] 0.73[138] 2.19[139] -0.51[140]
21 CYP39A1 24-hydroxycholesterol 7-alpha-hydroxylase [141] -2.79[142] -3.04[143] 2.31[144] -3.25[145] 0.66[146] 0.83[147]
22 OSBPL2 Oxysterol-binding protein-related protein 2 [148] 3.48[149] 3.20[150] 3.28[151] 2.40[152] 3.49[153] 0.82[154]
23 CYP7A1 Cholesterol 7-alpha-monooxygenase [155] -2.06[156] -4.46[157] -7.29[158] -8.29[159] [160] -2.60[161]
24 NCOA1 Nuclear receptor coactivator 1 [162] 2.74[163] 3.24[164] 4.14[165] 3.47[166] 4.88[167] 3.01[168]
25 OSBPL1A Oxysterol-binding protein-related protein 1 [169] -3.10[170] -4.37[171] 3.58[172] 3.58[173] 5.25[174] 2.01[175]
26 ABCB11 Bile salt export pump [176] -4.51[177] [178] -2.58[179] -3.84[180] [181] 5.14[182]
27 CYP7B1 25-hydroxycholesterol 7-alpha-hydroxylase [183] -5.75[184] -4.54[185] [186] -7.35[187] -1.66[188] 2.62[189]
28 NCOA2 Nuclear receptor coactivator 2 [190] 3.86[191] 4.61[192] 7.14[193] 4.88[194] 5.13[195] 4.95[196]
29 OSBPL3 Oxysterol-binding protein-related protein 3 [197] 5.92[198] 6.11[199] 6.55[200] 4.32[201] 6.70[202] 0.29[203]
30 OSBPL6 Oxysterol-binding protein-related protein 6 [204] -0.56[205] -1.13[206] 6.07[207] 1.27[208] 7.72[209] 2.65[210]
31 OSBPL7 Oxysterol-binding protein-related protein 7 [211] 4.57[212] 5.22[213] 0.05[214] 4.62[215] 6.82[216] 1.24[217]
32 PTGIS Prostacyclin synthase [218] 0.72[219] 1.77[220] 6.45[221] 2.80[222] 10.70[223] 5.19[224]
33 CYP46A1 Cholesterol 24-hydroxylase [225] -1.51[226] -0.24[227] -0.56[228] -0.88[229] 2.28[230] 2.61[231]
34 CH25H Cholesterol 25-hydroxylase [232] -0.86[233] [234] 0.13[235] 9.90[236] 5.35[237] 3.45[238]
[1]
ref_hepatocyte AKR1C1
Mean 1e+03
Standard deviation 4.3e+02
Values 1.4e+03 1.3e+03 9.2e+02 1e+03 3.2e+02
[2]
HepG2 AKR1C1
Mean 329
Standard deviation 2.6e+02
Values 5.1e+02 1.5e+02
[3]
HepG2.C3A AKR1C1
Mean 233
Standard deviation 65
Values 2.8e+02 1.9e+02
[4]
HuH.7 AKR1C1
Mean 17.1
Standard deviation 16
Values 7.8 35 8.5
[5]
SNU475 AKR1C1
Mean 254
Standard deviation 82
Values 2e+02 3.1e+02
[6]
THLE AKR1C1
Mean 10.3
Standard deviation 0.06
Values 10 10
[7]
liver AKR1C1
Mean 75.6
Standard deviation 54
Values 63 67 1.5e+02 21
[8]
ref_hepatocyte AKR1C3
Mean 242
Standard deviation 1.8e+02
Values 99 4.4e+02 1.1e+02 4.3e+02 1.2e+02
[9]
HepG2 AKR1C3
Mean 111
Standard deviation 53
Values 1.5e+02 74
[10]
HepG2.C3A AKR1C3
Mean 152
Standard deviation 34
Values 1.8e+02 1.3e+02
[11]
HuH.7 AKR1C3
Mean 1.46
Standard deviation 0.83
Values 1.1 2.4 0.84
[12]
SNU475 AKR1C3
Mean 580
Standard deviation 2.8e+02
Values 7.8e+02 3.9e+02
[13]
THLE AKR1C3
Mean 4.84
Standard deviation 0.00088
Values 4.8 4.8
[14]
liver AKR1C3
Mean 75.4
Standard deviation 53
Values 51 67 1.5e+02 32
[15]
ref_hepatocyte SCP2
Mean 227
Standard deviation 2.8e+02
Values 1.4e+02 77 9.1 2e+02 7.1e+02
[16]
HepG2 SCP2
Mean 35
Standard deviation 12
Values 27 43
[17]
HepG2.C3A SCP2
Mean 68.2
Standard deviation 19
Values 55 82
[18]
HuH.7 SCP2
Mean 78.3
Standard deviation 13
Values 83 63 89
[19]
SNU475 SCP2
Mean 38.6
Standard deviation 10
Values 46 32
[20]
THLE SCP2
Mean 38.9
Standard deviation 1.4
Values 40 38
[21]
liver SCP2
Mean 407
Standard deviation 2e+02
Values 6.5e+02 2.1e+02 4.9e+02 2.8e+02
[22]
ref_hepatocyte AKR1C2
Mean 167
Standard deviation 1.2e+02
Values 1.2e+02 3.4e+02 1.1e+02 2.3e+02 40
[23]
HepG2 AKR1C2
Mean 199
Standard deviation 1.3e+02
Values 2.9e+02 1e+02
[24]
HepG2.C3A AKR1C2
Mean 42.9
Standard deviation 7.5
Values 48 38
[25]
HuH.7 AKR1C2
Mean 6.67
Standard deviation 6.9
Values 3 15 2.5
[26]
SNU475 AKR1C2
Mean 215
Standard deviation 34
Values 2.4e+02 1.9e+02
[27]
THLE AKR1C2
Mean 3.9
Standard deviation 0.29
Values 4.1 3.7
[28]
liver AKR1C2
Mean 106
Standard deviation 92
Values 64 1.1e+02 2.3e+02 19
[29]
ref_hepatocyte CYP27A1
Mean 135
Standard deviation 1.6e+02
Values 62 8 18 2.1e+02 3.7e+02
[30]
HepG2 CYP27A1
Mean 70.5
Standard deviation 16
Values 59 82
[31]
HepG2.C3A CYP27A1
Mean 108
Standard deviation 25
Values 1.3e+02 90
[32]
HuH.7 CYP27A1
Mean 12.2
Standard deviation 7.3
Values 7.2 21 8.9
[33]
SNU475 CYP27A1
Mean 10.5
Standard deviation 1.6
Values 12 9.4
[34]
THLE CYP27A1
Mean 4.01
Standard deviation 0.91
Values 4.7 3.4
[35]
liver CYP27A1
Mean 204
Standard deviation 1e+02
Values 3.3e+02 1.2e+02 2.5e+02 1.1e+02
[36]
ref_hepatocyte AKR1C4
Mean 105
Standard deviation 1.4e+02
Values 0 3.6 1.7 2.3e+02 2.8e+02
[37]
HepG2 AKR1C4
Mean 0.432
Standard deviation 0.36
Values 0.69 0.18
[38]
HepG2.C3A AKR1C4
Mean 1.97
Standard deviation 0.48
Values 1.6 2.3
[39]
HuH.7 AKR1C4
Mean 1.26
Standard deviation 0.56
Values 0.75 1.9 1.2
[40]
SNU475 AKR1C4
Mean 0.118
Standard deviation 0.055
Values 0.079 0.16
[41]
THLE AKR1C4
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[42]
liver AKR1C4
Mean 80.8
Standard deviation 62
Values 56 66 1.7e+02 30
[43]
ref_hepatocyte HSD17B4
Mean 85.8
Standard deviation 51
Values 1.2e+02 57 11 1.1e+02 1.3e+02
[44]
HepG2 HSD17B4
Mean 70.1
Standard deviation 24
Values 53 87
[45]
HepG2.C3A HSD17B4
Mean 80.1
Standard deviation 0.22
Values 80 80
[46]
HuH.7 HSD17B4
Mean 64.3
Standard deviation 5.5
Values 68 58 67
[47]
SNU475 HSD17B4
Mean 39.5
Standard deviation 6.9
Values 44 35
[48]
THLE HSD17B4
Mean 70.3
Standard deviation 2.4
Values 69 72
[49]
liver HSD17B4
Mean 208
Standard deviation 20
Values 1.9e+02 2.2e+02 2.3e+02 1.9e+02
[50]
ref_hepatocyte SLC27A5
Mean 83.6
Standard deviation 1.2e+02
Values 0.8 1.2 6 1.4e+02 2.7e+02
[51]
HepG2 SLC27A5
Mean 4.25
Standard deviation 0.62
Values 4.7 3.8
[52]
HepG2.C3A SLC27A5
Mean 8.96
Standard deviation 1.1
Values 9.7 8.2
[53]
HuH.7 SLC27A5
Mean 2.84
Standard deviation 0.59
Values 2.3 2.7 3.5
[54]
SNU475 SLC27A5
Mean 0.856
Standard deviation 0.043
Values 0.83 0.89
[55]
THLE SLC27A5
Mean 0.169
Standard deviation 0.036
Values 0.2 0.14
[56]
liver SLC27A5
Mean 184
Standard deviation 60
Values 2.2e+02 1.1e+02 2.5e+02 1.6e+02
[57]
ref_hepatocyte SLC27A2
Mean 66.6
Standard deviation 61
Values 7.2 40 22 1.4e+02 1.2e+02
[58]
HepG2 SLC27A2
Mean 12.7
Standard deviation 1.5
Values 12 14
[59]
HepG2.C3A SLC27A2
Mean 12.6
Standard deviation 2.5
Values 14 11
[60]
HuH.7 SLC27A2
Mean 10.1
Standard deviation 2.6
Values 8.2 13 9.1
[61]
SNU475 SLC27A2
Mean 7.28
Standard deviation 1.4
Values 8.2 6.3
[62]
THLE SLC27A2
Mean 0.539
Standard deviation 0.043
Values 0.51 0.57
[63]
liver SLC27A2
Mean 212
Standard deviation 71
Values 1.1e+02 2.6e+02 2.6e+02 2.2e+02
[64]
ref_hepatocyte BAAT
Mean 50.1
Standard deviation 39
Values 1.6 59 17 89 84
[65]
HepG2 BAAT
Mean 2.42
Standard deviation 0.81
Values 1.9 3
[66]
HepG2.C3A BAAT
Mean 3.29
Standard deviation 0.29
Values 3.5 3.1
[67]
HuH.7 BAAT
Mean 0.621
Standard deviation 0.84
Values 0.098 1.6 0.18
[68]
SNU475 BAAT
Mean 0.302
Standard deviation 0.27
Values 0.49 0.11
[69]
THLE BAAT
Mean 0.136
Standard deviation 0.042
Values 0.17 0.11
[70]
liver BAAT
Mean 239
Standard deviation 1.3e+02
Values 4.1e+02 1.7e+02 2.7e+02 1.1e+02
[71]
ref_hepatocyte CYP8B1
Mean 34.6
Standard deviation 44
Values 1.2 0.33 6.4 79 86
[72]
HepG2 CYP8B1
Mean 0.257
Standard deviation 0.2
Values 0.11 0.4
[73]
HepG2.C3A CYP8B1
Mean 1.33
Standard deviation 0.5
Values 1.7 0.98
[74]
HuH.7 CYP8B1
Mean 0.084
Standard deviation 0.016
Values 0.09 0.096 0.066
[75]
SNU475 CYP8B1
Mean 0.0631
Standard deviation 0.004
Values 0.06 0.066
[76]
THLE CYP8B1
Mean 0.0198
Standard deviation 0.0054
Values 0.024 0.016
[77]
liver CYP8B1
Mean 269
Standard deviation 1.3e+02
Values 4.2e+02 1.3e+02 3e+02 2.2e+02
[78]
ref_hepatocyte HSD3B7
Mean 30.9
Standard deviation 9.6
Values 18 42 26 31 38
[79]
HepG2 HSD3B7
Mean 29.1
Standard deviation 6.4
Values 25 34
[80]
HepG2.C3A HSD3B7
Mean 46.7
Standard deviation 4.6
Values 43 50
[81]
HuH.7 HSD3B7
Mean 5.15
Standard deviation 1.4
Values 4.5 6.7 4.2
[82]
SNU475 HSD3B7
Mean 5.15
Standard deviation 1.7
Values 6.4 3.9
[83]
THLE HSD3B7
Mean 4.37
Standard deviation 0.17
Values 4.2 4.5
[84]
liver HSD3B7
Mean 55.4
Standard deviation 32
Values 95 26 66 35
[85]
ref_hepatocyte AKR1D1
Mean 25.3
Standard deviation 42
Values 4.5 0.35 0.37 23 99
[86]
HepG2 AKR1D1
Mean 6.61
Standard deviation 3
Values 4.5 8.7
[87]
HepG2.C3A AKR1D1
Mean 15.2
Standard deviation 0.35
Values 15 15
[88]
HuH.7 AKR1D1
Mean 2.24
Standard deviation 3.1
Values 0.38 5.8 0.5
[89]
SNU475 AKR1D1
Mean 0.042
Standard deviation 0.027
Values 0.023 0.061
[90]
THLE AKR1D1
Mean 0.0402
Standard deviation 0.027
Values 0.059 0.021
[91]
liver AKR1D1
Mean 29.7
Standard deviation 5.8
Values 23 35 26 34
[92]
ref_hepatocyte OSBPL9
Mean 22.1
Standard deviation 9
Values 28 33 11 17 21
[93]
HepG2 OSBPL9
Mean 49
Standard deviation 15
Values 39 60
[94]
HepG2.C3A OSBPL9
Mean 58.7
Standard deviation 11
Values 51 67
[95]
HuH.7 OSBPL9
Mean 58.1
Standard deviation 3.3
Values 57 62 55
[96]
SNU475 OSBPL9
Mean 62.8
Standard deviation 14
Values 73 53
[97]
THLE OSBPL9
Mean 53.6
Standard deviation 0.54
Values 54 53
[98]
liver OSBPL9
Mean 54.5
Standard deviation 4.6
Values 57 56 48 57
[99]
ref_hepatocyte NR1H4
Mean 20.8
Standard deviation 17
Values 15 9.3 3.8 43 33
[100]
HepG2 NR1H4
Mean 15.2
Standard deviation 6.4
Values 11 20
[101]
HepG2.C3A NR1H4
Mean 20.3
Standard deviation 1.1
Values 19 21
[102]
HuH.7 NR1H4
Mean 67.4
Standard deviation 13
Values 62 82 58
[103]
SNU475 NR1H4
Mean 0.144
Standard deviation 0.04
Values 0.12 0.17
[104]
THLE NR1H4
Mean 0.158
Standard deviation 0.028
Values 0.18 0.14
[105]
liver NR1H4
Mean 42.4
Standard deviation 11
Values 59 37 35 39
[106]
ref_hepatocyte ACOX2
Mean 19.6
Standard deviation 24
Values 4.4 1.3 1.6 39 52
[107]
HepG2 ACOX2
Mean 8.11
Standard deviation 2.8
Values 6.1 10
[108]
HepG2.C3A ACOX2
Mean 18
Standard deviation 1.3
Values 17 19
[109]
HuH.7 ACOX2
Mean 14.5
Standard deviation 1.3
Values 13 15 15
[110]
SNU475 ACOX2
Mean 0.154
Standard deviation 0.11
Values 0.074 0.23
[111]
THLE ACOX2
Mean 0.86
Standard deviation 0.15
Values 0.96 0.76
[112]
liver ACOX2
Mean 60.6
Standard deviation 24
Values 91 37 69 45
[113]
ref_hepatocyte RXRA
Mean 14.5
Standard deviation 6.1
Values 15 7.5 9.4 22 18
[114]
HepG2 RXRA
Mean 30.9
Standard deviation 2.8
Values 33 29
[115]
HepG2.C3A RXRA
Mean 23.9
Standard deviation 6.1
Values 28 20
[116]
HuH.7 RXRA
Mean 41.2
Standard deviation 10
Values 42 51 30
[117]
SNU475 RXRA
Mean 26.9
Standard deviation 8.3
Values 33 21
[118]
THLE RXRA
Mean 23.9
Standard deviation 7.5
Values 19 29
[119]
liver RXRA
Mean 91.4
Standard deviation 37
Values 1.3e+02 72 49 1.2e+02
[120]
ref_hepatocyte OSBP
Mean 12.2
Standard deviation 4.2
Values 8.9 8.9 10 19 14
[121]
HepG2 OSBP
Mean 30.7
Standard deviation 3.1
Values 29 33
[122]
HepG2.C3A OSBP
Mean 31.2
Standard deviation 8.1
Values 37 25
[123]
HuH.7 OSBP
Mean 86.5
Standard deviation 8
Values 88 93 78
[124]
SNU475 OSBP
Mean 31
Standard deviation 1
Values 32 30
[125]
THLE OSBP
Mean 31.5
Standard deviation 3.5
Values 29 34
[126]
liver OSBP
Mean 61.7
Standard deviation 29
Values 38 88 36 85
[127]
ref_hepatocyte AMACR
Mean 11.6
Standard deviation 11
Values 5.6 4.7 2.4 17 28
[128]
HepG2 AMACR
Mean 1.76
Standard deviation 1
Values 1 2.5
[129]
HepG2.C3A AMACR
Mean 1.58
Standard deviation 0.45
Values 1.3 1.9
[130]
HuH.7 AMACR
Mean 4.17
Standard deviation 1.7
Values 3.7 6.1 2.7
[131]
SNU475 AMACR
Mean 0.891
Standard deviation 0.32
Values 1.1 0.66
[132]
THLE AMACR
Mean 0.744
Standard deviation 0.26
Values 0.56 0.93
[133]
liver AMACR
Mean 4.64
Standard deviation 1.1
Values 5.7 3.1 5.1 4.7
[134]
ref_hepatocyte ACOT8
Mean 9.09
Standard deviation 5.1
Values 7.6 4.2 4.6 14 15
[135]
HepG2 ACOT8
Mean 10.5
Standard deviation 0.047
Values 10 10
[136]
HepG2.C3A ACOT8
Mean 12.9
Standard deviation 0.35
Values 13 13
[137]
HuH.7 ACOT8
Mean 12.8
Standard deviation 3.6
Values 14 8.8 16
[138]
SNU475 ACOT8
Mean 8.62
Standard deviation 1.7
Values 9.8 7.4
[139]
THLE ACOT8
Mean 6.83
Standard deviation 0.25
Values 6.7 7
[140]
liver ACOT8
Mean 7.1
Standard deviation 3.2
Values 9.8 5.3 9.8 3.5
[141]
ref_hepatocyte CYP39A1
Mean 7.02
Standard deviation 11
Values 0.052 1.3 0.69 8.1 25
[142]
HepG2 CYP39A1
Mean 0.464
Standard deviation 0.049
Values 0.5 0.43
[143]
HepG2.C3A CYP39A1
Mean 0.363
Standard deviation 0.032
Values 0.34 0.39
[144]
HuH.7 CYP39A1
Mean 8.71
Standard deviation 0.36
Values 8.7 9.1 8.4
[145]
SNU475 CYP39A1
Mean 0.422
Standard deviation 0.11
Values 0.35 0.5
[146]
THLE CYP39A1
Mean 1.83
Standard deviation 0.14
Values 1.9 1.7
[147]
liver CYP39A1
Mean 13.9
Standard deviation 9.4
Values 28 8.3 13 7.1
[148]
ref_hepatocyte OSBPL2
Mean 6.69
Standard deviation 3.3
Values 12 4.8 6.9 5.2 4.3
[149]
HepG2 OSBPL2
Mean 33.9
Standard deviation 0.64
Values 34 33
[150]
HepG2.C3A OSBPL2
Mean 26.1
Standard deviation 9
Values 32 20
[151]
HuH.7 OSBPL2
Mean 16.3
Standard deviation 1.8
Values 15 18 16
[152]
SNU475 OSBPL2
Mean 20.3
Standard deviation 6.6
Values 25 16
[153]
THLE OSBPL2
Mean 12.4
Standard deviation 0.81
Values 12 13
[154]
liver OSBPL2
Mean 13.1
Standard deviation 2.8
Values 16 10 15 11
[155]
ref_hepatocyte CYP7A1
Mean 4.03
Standard deviation 5.2
Values 9.8 0 0 0.69 9.7
[156]
HepG2 CYP7A1
Mean 0.438
Standard deviation 0.47
Values 0.11 0.77
[157]
HepG2.C3A CYP7A1
Mean 0.0774
Standard deviation 0.027
Values 0.058 0.097
[158]
HuH.7 CYP7A1
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[159]
SNU475 CYP7A1
Mean 0.00739
Standard deviation 0.0039
Values 0.0046 0.01
[160]
THLE CYP7A1
Mean 0
Standard deviation 0
Values 0 0
[161]
liver CYP7A1
Mean 0.737
Standard deviation 0.45
Values 1.1 0.94 0.82 0.079
[162]
ref_hepatocyte NCOA1
Mean 2.09
Standard deviation 0.73
Values 1.8 2 1.1 2.8 2.8
[163]
HepG2 NCOA1
Mean 6.38
Standard deviation 1.4
Values 5.4 7.4
[164]
HepG2.C3A NCOA1
Mean 8.42
Standard deviation 0.79
Values 7.9 9
[165]
HuH.7 NCOA1
Mean 9.25
Standard deviation 2.7
Values 9.2 12 6.6
[166]
SNU475 NCOA1
Mean 13.3
Standard deviation 1
Values 14 13
[167]
THLE NCOA1
Mean 10.2
Standard deviation 0.47
Values 9.9 11
[168]
liver NCOA1
Mean 18.7
Standard deviation 4.8
Values 17 23 13 22
[169]
ref_hepatocyte OSBPL1A
Mean 1.99
Standard deviation 1.5
Values 0 1.7 1.5 3 3.8
[170]
HepG2 OSBPL1A
Mean 0.106
Standard deviation 0.0042
Values 0.11 0.1
[171]
HepG2.C3A OSBPL1A
Mean 0.0409
Standard deviation 0.0028
Values 0.039 0.043
[172]
HuH.7 OSBPL1A
Mean 5.95
Standard deviation 0.96
Values 7 5.3 5.5
[173]
SNU475 OSBPL1A
Mean 13.6
Standard deviation 4.9
Values 17 10
[174]
THLE OSBPL1A
Mean 12.5
Standard deviation 1
Values 12 13
[175]
liver OSBPL1A
Mean 8.93
Standard deviation 4.5
Values 16 6.7 6.7 6.6
[176]
ref_hepatocyte ABCB11
Mean 1.97
Standard deviation 1.6
Values 0 1 1.8 3 4.1
[177]
HepG2 ABCB11
Mean 0.0394
Standard deviation 0.025
Values 0.057 0.021
[178]
HepG2.C3A ABCB11
Mean 0
Standard deviation 0
Values 0 0
[179]
HuH.7 ABCB11
Mean 0.0829
Standard deviation 0.04
Values 0.11 0.096 0.037
[180]
SNU475 ABCB11
Mean 0.0787
Standard deviation 0.039
Values 0.051 0.11
[181]
THLE ABCB11
Mean 0
Standard deviation 0
Values 0 0
[182]
liver ABCB11
Mean 77.6
Standard deviation 77
Values 17 1.9e+02 36 71
[183]
ref_hepatocyte CYP7B1
Mean 1.44
Standard deviation 1
Values 0 2.2 1.1 1.2 2.7
[184]
HepG2 CYP7B1
Mean 0.0122
Standard deviation 0.001
Values 0.011 0.013
[185]
HepG2.C3A CYP7B1
Mean 0.0263
Standard deviation 0.023
Values 0.0097 0.043
[186]
HuH.7 CYP7B1
Mean 0
Standard deviation 0
Values 0 0 0
[187]
SNU475 CYP7B1
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[188]
THLE CYP7B1
Mean 0.0751
Standard deviation 0.014
Values 0.065 0.085
[189]
liver CYP7B1
Mean 9.87
Standard deviation 5.4
Values 6.3 17 4.8 12
[190]
ref_hepatocyte NCOA2
Mean 1.14
Standard deviation 0.47
Values 1.5 1.7 1.2 0.47 0.91
[191]
HepG2 NCOA2
Mean 7.51
Standard deviation 4.4
Values 4.4 11
[192]
HepG2.C3A NCOA2
Mean 11.8
Standard deviation 4.3
Values 8.7 15
[193]
HuH.7 NCOA2
Mean 40.1
Standard deviation 18
Values 55 45 21
[194]
SNU475 NCOA2
Mean 19.2
Standard deviation 3.8
Values 22 17
[195]
THLE NCOA2
Mean 6.6
Standard deviation 1.4
Values 5.6 7.6
[196]
liver NCOA2
Mean 39.3
Standard deviation 20
Values 25 56 20 57
[197]
ref_hepatocyte OSBPL3
Mean 0.787
Standard deviation 0.96
Values 2.3 1.2 0.24 0.069 0.15
[198]
HepG2 OSBPL3
Mean 21.7
Standard deviation 2.5
Values 20 23
[199]
HepG2.C3A OSBPL3
Mean 23
Standard deviation 4.5
Values 20 26
[200]
HuH.7 OSBPL3
Mean 18.4
Standard deviation 4.7
Values 23 14 18
[201]
SNU475 OSBPL3
Mean 9.02
Standard deviation 2.2
Values 7.5 11
[202]
THLE OSBPL3
Mean 13.5
Standard deviation 1.2
Values 13 14
[203]
liver OSBPL3
Mean 1.07
Standard deviation 0.32
Values 1.5 0.98 0.69 1.1
[204]
ref_hepatocyte OSBPL6
Mean 0.506
Standard deviation 0.35
Values 0 0.81 0.82 0.59 0.31
[205]
HepG2 OSBPL6
Mean 0.156
Standard deviation 0.039
Values 0.18 0.13
[206]
HepG2.C3A OSBPL6
Mean 0.0984
Standard deviation 0.043
Values 0.068 0.13
[207]
HuH.7 OSBPL6
Mean 8.49
Standard deviation 1.9
Values 8.5 10 6.6
[208]
SNU475 OSBPL6
Mean 0.7
Standard deviation 0.62
Values 0.26 1.1
[209]
THLE OSBPL6
Mean 17.7
Standard deviation 0.86
Values 17 18
[210]
liver OSBPL6
Mean 3.54
Standard deviation 0.68
Values 4.5 3.4 3 3.2
[211]
ref_hepatocyte OSBPL7
Mean 0.278
Standard deviation 0.42
Values 1 0.065 0.14 0.12 0.041
[212]
HepG2 OSBPL7
Mean 3
Standard deviation 0.61
Values 2.6 3.4
[213]
HepG2.C3A OSBPL7
Mean 4.39
Standard deviation 1
Values 5.1 3.7
[214]
HuH.7 OSBPL7
Mean 0.0722
Standard deviation 0.066
Values 0.041 0.15 0.028
[215]
SNU475 OSBPL7
Mean 3.92
Standard deviation 1.8
Values 5.2 2.7
[216]
THLE OSBPL7
Mean 5.2
Standard deviation 0.95
Values 5.9 4.5
[217]
liver OSBPL7
Mean 0.732
Standard deviation 0.11
Values 0.68 0.76 0.62 0.87
[218]
ref_hepatocyte PTGIS
Mean 0.218
Standard deviation 0.14
Values 0.14 0.08 0.32 0.4 0.15
[219]
HepG2 PTGIS
Mean 0.163
Standard deviation 0.012
Values 0.17 0.15
[220]
HepG2.C3A PTGIS
Mean 0.316
Standard deviation 0.0069
Values 0.32 0.31
[221]
HuH.7 PTGIS
Mean 4.77
Standard deviation 0.64
Values 5.5 4.3 4.5
[222]
SNU475 PTGIS
Mean 0.868
Standard deviation 0.11
Values 0.79 0.94
[223]
THLE PTGIS
Mean 59.9
Standard deviation 32
Values 37 82
[224]
liver PTGIS
Mean 8.86
Standard deviation 2.8
Values 5.9 11 12 7.1
[225]
ref_hepatocyte CYP46A1
Mean 0.0447
Standard deviation 0.068
Values 0 0 0 0.069 0.15
[226]
HepG2 CYP46A1
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[227]
HepG2.C3A CYP46A1
Mean 0.0161
Standard deviation 0.023
Values 0 0.032
[228]
HuH.7 CYP46A1
Mean 0.00761
Standard deviation 0.0083
Values 0.016 0.0064 0
[229]
SNU475 CYP46A1
Mean 0.0139
Standard deviation 0.02
Values 0.028 0
[230]
THLE CYP46A1
Mean 0.0358
Standard deviation 0.017
Values 0.024 0.048
[231]
liver CYP46A1
Mean 0.303
Standard deviation 0.093
Values 0.38 0.17 0.36 0.3
[232]
ref_hepatocyte CH25H
Mean 0.0114
Standard deviation 0.025
Values 0 0 0 0 0.057
[233]
HepG2 CH25H
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[234]
HepG2.C3A CH25H
Mean 0
Standard deviation 0
Values 0 0
[235]
HuH.7 CH25H
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[236]
SNU475 CH25H
Mean 6.24
Standard deviation 0.89
Values 5.6 6.9
[237]
THLE CH25H
Mean 0.0766
Standard deviation 0.05
Values 0.041 0.11
[238]
liver CH25H
Mean 0.138
Standard deviation 0.14
Values 0.28 0.014 0.23 0.026