REACTOME_SYNTHESIS_OF_5_EICOSATETRAENOIC_ACIDS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GPX2 Glutathione peroxidase 2 [1] 0.70[2] 0.19[3] -1.52[4] -7.86[5] -8.35[6] 0.08[7]
2 GPX4 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial [8] -0.25[9] 0.31[10] 0.44[11] 0.64[12] -0.08[13] -1.16[14]
3 GPX1 Glutathione peroxidase 1 [15] 0.03[16] -0.13[17] 0.68[18] 1.02[19] 1.68[20] -0.90[21]
4 PON1 Serum paraoxonase/arylesterase 1 [22] -6.96[23] -4.04[24] -1.68[25] -8.93[26] -9.60[27] 1.14[28]
5 PON3 Serum paraoxonase/lactonase 3 [29] -2.60[30] -2.22[31] -2.94[32] -5.17[33] -10.84[34] 0.38[35]
6 PON2 Serum paraoxonase/arylesterase 2 [36] 1.15[37] 1.39[38] 1.53[39] 1.50[40] 1.03[41] 0.41[42]
7 ALOX5AP Arachidonate 5-lipoxygenase-activating protein [43] -0.46[44] -2.14[45] -0.31[46] 3.15[47] 2.29[48] 0.30[49]
8 ALOX5 Arachidonate 5-lipoxygenase [50] 0.68[51] -4.50[52] -3.99[53] -3.83[54] -2.88[55] 3.45[56]
9 LTC4S Leukotriene C4 synthase [57] -1.36[58] 0.30[59] -0.64[60] -2.52[61] 0.50[62] 1.17[63]
[1]
ref_hepatocyte GPX2
Mean 224
Standard deviation 2.7e+02
Values 61 9.6 19 5.9e+02 4.5e+02
[2]
HepG2 GPX2
Mean 274
Standard deviation 26
Values 2.9e+02 2.6e+02
[3]
HepG2.C3A GPX2
Mean 153
Standard deviation 85
Values 93 2.1e+02
[4]
HuH.7 GPX2
Mean 33.1
Standard deviation 7.7
Values 37 24 38
[5]
SNU475 GPX2
Mean 0.18
Standard deviation 0.025
Values 0.16 0.2
[6]
THLE GPX2
Mean 0.178
Standard deviation 0.026
Values 0.16 0.2
[7]
liver GPX2
Mean 218
Standard deviation 2.6e+02
Values 2.6e+02 30 5.7e+02 6.4
[8]
ref_hepatocyte GPX4
Mean 223
Standard deviation 63
Values 3.1e+02 1.4e+02 2.2e+02 2e+02 2.5e+02
[9]
HepG2 GPX4
Mean 141
Standard deviation 10
Values 1.5e+02 1.3e+02
[10]
HepG2.C3A GPX4
Mean 164
Standard deviation 3.3
Values 1.7e+02 1.6e+02
[11]
HuH.7 GPX4
Mean 128
Standard deviation 29
Values 1.1e+02 1.1e+02 1.6e+02
[12]
SNU475 GPX4
Mean 64.8
Standard deviation 11
Values 73 57
[13]
THLE GPX4
Mean 54.8
Standard deviation 1.7
Values 54 56
[14]
liver GPX4
Mean 91.2
Standard deviation 88
Values 1.7e+02 18 1.6e+02 12
[15]
ref_hepatocyte GPX1
Mean 167
Standard deviation 1e+02
Values 30 1e+02 2.7e+02 2.5e+02 1.8e+02
[16]
HepG2 GPX1
Mean 128
Standard deviation 3.5
Values 1.3e+02 1.3e+02
[17]
HepG2.C3A GPX1
Mean 91.1
Standard deviation 33
Values 67 1.1e+02
[18]
HuH.7 GPX1
Mean 113
Standard deviation 55
Values 1.2e+02 55 1.6e+02
[19]
SNU475 GPX1
Mean 63.3
Standard deviation 6.4
Values 68 59
[20]
THLE GPX1
Mean 139
Standard deviation 16
Values 1.3e+02 1.5e+02
[21]
liver GPX1
Mean 81.8
Standard deviation 69
Values 1.4e+02 25 1.4e+02 19
[22]
ref_hepatocyte PON1
Mean 109
Standard deviation 1.5e+02
Values 0.068 2.6 2.5 2.1e+02 3.3e+02
[23]
HepG2 PON1
Mean 0.654
Standard deviation 0.4
Values 0.37 0.94
[24]
HepG2.C3A PON1
Mean 3.94
Standard deviation 0.73
Values 4.5 3.4
[25]
HuH.7 PON1
Mean 14.4
Standard deviation 7.6
Values 9.6 23 10
[26]
SNU475 PON1
Mean 0.0416
Standard deviation 0.013
Values 0.032 0.051
[27]
THLE PON1
Mean 0.0364
Standard deviation 0.0012
Values 0.035 0.037
[28]
liver PON1
Mean 220
Standard deviation 1.9e+02
Values 4.8e+02 82 2.4e+02 76
[29]
ref_hepatocyte PON3
Mean 101
Standard deviation 1.4e+02
Values 4.1 3.8 6.8 1.8e+02 3e+02
[30]
HepG2 PON3
Mean 12.4
Standard deviation 1.5
Values 11 14
[31]
HepG2.C3A PON3
Mean 12.9
Standard deviation 4.1
Values 10 16
[32]
HuH.7 PON3
Mean 5.57
Standard deviation 1.1
Values 5.1 4.8 6.8
[33]
SNU475 PON3
Mean 0.521
Standard deviation 0.15
Values 0.41 0.63
[34]
THLE PON3
Mean 0.0142
Standard deviation 0.005
Values 0.018 0.011
[35]
liver PON3
Mean 120
Standard deviation 85
Values 2.2e+02 57 1.6e+02 40
[36]
ref_hepatocyte PON2
Mean 68.4
Standard deviation 35
Values 55 99 18 1e+02 66
[37]
HepG2 PON2
Mean 114
Standard deviation 33
Values 90 1.4e+02
[38]
HepG2.C3A PON2
Mean 107
Standard deviation 51
Values 71 1.4e+02
[39]
HuH.7 PON2
Mean 84
Standard deviation 18
Values 85 66 1e+02
[40]
SNU475 PON2
Mean 36.1
Standard deviation 8.6
Values 42 30
[41]
THLE PON2
Mean 36.2
Standard deviation 0.65
Values 36 37
[42]
liver PON2
Mean 83.1
Standard deviation 53
Values 1.5e+02 42 1.1e+02 37
[43]
ref_hepatocyte ALOX5AP
Mean 0.929
Standard deviation 0.85
Values 0.13 0 1.2 1.3 2
[44]
HepG2 ALOX5AP
Mean 0.507
Standard deviation 0.0044
Values 0.5 0.51
[45]
HepG2.C3A ALOX5AP
Mean 0.126
Standard deviation 0.095
Values 0.058 0.19
[46]
HuH.7 ALOX5AP
Mean 0.318
Standard deviation 0.44
Values 0.049 0.82 0.084
[47]
SNU475 ALOX5AP
Mean 1.54
Standard deviation 0.32
Values 1.8 1.3
[48]
THLE ALOX5AP
Mean 1.18
Standard deviation 0.56
Values 0.79 1.6
[49]
liver ALOX5AP
Mean 1.05
Standard deviation 0.72
Values 1.5 0.46 1.8 0.41
[50]
ref_hepatocyte ALOX5
Mean 0.387
Standard deviation 0.51
Values 0 0.18 0 0.53 1.2
[51]
HepG2 ALOX5
Mean 0.467
Standard deviation 0.66
Values 0.93 0
[52]
HepG2.C3A ALOX5
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[53]
HuH.7 ALOX5
Mean 0.0103
Standard deviation 0.013
Values 0.025 0.0064 0
[54]
SNU475 ALOX5
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[55]
THLE ALOX5
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[56]
liver ALOX5
Mean 3.87
Standard deviation 1.4
Values 2.2 4.4 3.4 5.5
[57]
ref_hepatocyte LTC4S
Mean 0.22
Standard deviation 0.38
Values 0 0 0 0.22 0.88
[58]
HepG2 LTC4S
Mean 0.0644
Standard deviation 0.055
Values 0.1 0.026
[59]
HepG2.C3A LTC4S
Mean 0.162
Standard deviation 0.046
Values 0.19 0.13
[60]
HuH.7 LTC4S
Mean 0.0599
Standard deviation 0.031
Values 0.025 0.071 0.084
[61]
SNU475 LTC4S
Mean 0.00717
Standard deviation 0.003
Values 0.0093 0.0051
[62]
THLE LTC4S
Mean 0.081
Standard deviation 0.0058
Values 0.077 0.085
[63]
liver LTC4S
Mean 0.455
Standard deviation 0.39
Values 0.89 0.13 0.67 0.13