REACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CYP2C8 Cytochrome P450 2C8 [1] -8.52[2] -4.20[3] -3.06[4] -7.17[5] [6] -0.12[7]
2 CYP2C9 Cytochrome P450 2C9 [8] [9] -9.12[10] -3.28[11] -9.86[12] -11.24[13] 0.39[14]
3 CYP4A11 Cytochrome P450 4A11 [15] -6.70[16] -4.48[17] -7.41[18] -5.99[19] -9.19[20] 0.24[21]
4 CYP1A2 Cytochrome P450 1A2 [22] -2.95[23] -2.07[24] -3.78[25] -3.75[26] -6.35[27] -2.29[28]
5 CYP1A1 Cytochrome P450 1A1 [29] 3.50[30] 1.50[31] 4.10[32] 0.85[33] -1.87[34] -6.43[35]
6 CYP4F2 Phylloquinone omega-hydroxylase CYP4F2 [36] 1.34[37] 4.55[38] -8.20[39] -7.21[40] -7.50[41] 0.18[42]
7 CYP2C19 Cytochrome P450 2C19 [43] [44] [45] -0.42[46] -7.55[47] -9.55[48] 0.94[49]
8 CYP1B1 Cytochrome P450 1B1 [50] 0.92[51] 1.07[52] 4.12[53] 7.84[54] 8.27[55] 0.38[56]
9 CYP2U1 Cytochrome P450 2U1 [57] 8.14[58] 3.93[59] 3.07[60] 7.57[61] 6.18[62] 1.44[63]
[1]
ref_hepatocyte CYP2C8
Mean 328
Standard deviation 4.4e+02
Values 0 1.2 19 7.1e+02 9.1e+02
[2]
HepG2 CYP2C8
Mean 0.00788
Standard deviation 0.0051
Values 0.011 0.0043
[3]
HepG2.C3A CYP2C8
Mean 0.186
Standard deviation 0.071
Values 0.14 0.24
[4]
HuH.7 CYP2C8
Mean 0.822
Standard deviation 1
Values 0.16 2 0.3
[5]
SNU475 CYP2C8
Mean 0.0515
Standard deviation 0.02
Values 0.037 0.066
[6]
THLE CYP2C8
Mean 0
Standard deviation 0
Values 0 0
[7]
liver CYP2C8
Mean 666
Standard deviation 3.9e+02
Values 6.8e+02 6.2e+02 1.2e+03 2e+02
[8]
ref_hepatocyte CYP2C9
Mean 285
Standard deviation 4.1e+02
Values 0.064 20 21 4.7e+02 9.2e+02
[9]
HepG2 CYP2C9
Mean 0
Standard deviation 0
Values 0 0
[10]
HepG2.C3A CYP2C9
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[11]
HuH.7 CYP2C9
Mean 0.616
Standard deviation 0.63
Values 0.25 1.3 0.25
[12]
SNU475 CYP2C9
Mean 0.00696
Standard deviation 0.0098
Values 0.014 0
[13]
THLE CYP2C9
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[14]
liver CYP2C9
Mean 822
Standard deviation 5.3e+02
Values 8.6e+02 6.1e+02 1.5e+03 2.9e+02
[15]
ref_hepatocyte CYP4A11
Mean 109
Standard deviation 1.6e+02
Values 0 0 4 2e+02 3.4e+02
[16]
HepG2 CYP4A11
Mean 0.0093
Standard deviation 0.005
Values 0.0057 0.013
[17]
HepG2.C3A CYP4A11
Mean 0.0511
Standard deviation 0.0036
Values 0.049 0.054
[18]
HuH.7 CYP4A11
Mean 0.0135
Standard deviation 0.0098
Values 0.025 0.0064 0.0094
[19]
SNU475 CYP4A11
Mean 0.039
Standard deviation 0.0093
Values 0.032 0.046
[20]
THLE CYP4A11
Mean 0.0216
Standard deviation 0.022
Values 0.0059 0.037
[21]
liver CYP4A11
Mean 286
Standard deviation 2.2e+02
Values 5.7e+02 87 3.6e+02 1.3e+02
[22]
ref_hepatocyte CYP1A2
Mean 78.9
Standard deviation 1.3e+02
Values 0.4 18 0.97 71 3e+02
[23]
HepG2 CYP1A2
Mean 0.0901
Standard deviation 0.055
Values 0.052 0.13
[24]
HepG2.C3A CYP1A2
Mean 0.197
Standard deviation 0.066
Values 0.24 0.15
[25]
HuH.7 CYP1A2
Mean 0.12
Standard deviation 0.026
Values 0.11 0.1 0.15
[26]
SNU475 CYP1A2
Mean 0.134
Standard deviation 0.091
Values 0.07 0.2
[27]
THLE CYP1A2
Mean 0.112
Standard deviation 0.068
Values 0.16 0.064
[28]
liver CYP1A2
Mean 35.7
Standard deviation 24
Values 55 12 58 19
[29]
ref_hepatocyte CYP1A1
Mean 43.8
Standard deviation 36
Values 77 43 0.06 17 82
[30]
HepG2 CYP1A1
Mean 4.39
Standard deviation 2.6
Values 6.2 2.6
[31]
HepG2.C3A CYP1A1
Mean 1.3
Standard deviation 0.1
Values 1.4 1.2
[32]
HuH.7 CYP1A1
Mean 15.8
Standard deviation 1.4
Values 14 17 17
[33]
SNU475 CYP1A1
Mean 1.8
Standard deviation 1.8
Values 0.49 3.1
[34]
THLE CYP1A1
Mean 1.38
Standard deviation 0.04
Values 1.4 1.4
[35]
liver CYP1A1
Mean 1.12
Standard deviation 0.58
Values 1.2 0.47 0.92 1.8
[36]
ref_hepatocyte CYP4F2
Mean 30.2
Standard deviation 38
Values 1.2 0.054 11 51 87
[37]
HepG2 CYP4F2
Mean 0.677
Standard deviation 0.5
Values 1 0.32
[38]
HepG2.C3A CYP4F2
Mean 7.41
Standard deviation 4.8
Values 11 4
[39]
HuH.7 CYP4F2
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[40]
SNU475 CYP4F2
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[41]
THLE CYP4F2
Mean 0.0192
Standard deviation 0.01
Values 0.012 0.027
[42]
liver CYP4F2
Mean 75.6
Standard deviation 42
Values 86 50 1.3e+02 36
[43]
ref_hepatocyte CYP2C19
Mean 19.2
Standard deviation 30
Values 0 5.9 0 18 72
[44]
HepG2 CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[45]
HepG2.C3A CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 CYP2C19
Mean 0.3
Standard deviation 0.27
Values 0.098 0.6 0.2
[47]
SNU475 CYP2C19
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[48]
THLE CYP2C19
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[49]
liver CYP2C19
Mean 81.4
Standard deviation 39
Values 65 92 1.3e+02 38
[50]
ref_hepatocyte CYP1B1
Mean 2.62
Standard deviation 3.2
Values 0.024 8 0.92 2.7 1.4
[51]
HepG2 CYP1B1
Mean 0.0437
Standard deviation 0.019
Values 0.057 0.03
[52]
HepG2.C3A CYP1B1
Mean 0.0575
Standard deviation 0.04
Values 0.029 0.086
[53]
HuH.7 CYP1B1
Mean 0.95
Standard deviation 0.082
Values 0.87 1 0.95
[54]
SNU475 CYP1B1
Mean 13.6
Standard deviation 3.1
Values 16 11
[55]
THLE CYP1B1
Mean 93
Standard deviation 14
Values 1e+02 83
[56]
liver CYP1B1
Mean 7.5
Standard deviation 1.4
Values 6.9 7.4 9.5 6.2
[57]
ref_hepatocyte CYP2U1
Mean 1.09
Standard deviation 0.48
Values 0.81 1.1 0.46 1.4 1.7
[58]
HepG2 CYP2U1
Mean 2.73
Standard deviation 0.62
Values 2.3 3.2
[59]
HepG2.C3A CYP2U1
Mean 0.173
Standard deviation 0.15
Values 0.068 0.28
[60]
HuH.7 CYP2U1
Mean 0.192
Standard deviation 0.045
Values 0.16 0.17 0.24
[61]
SNU475 CYP2U1
Mean 4.71
Standard deviation 1
Values 5.4 4
[62]
THLE CYP2U1
Mean 9.13
Standard deviation 0.16
Values 9 9.2
[63]
liver CYP2U1
Mean 6.54
Standard deviation 1.6
Values 5.5 8.3 7.4 5