REACTOME_SYNTHESIS_OF_12_EICOSATETRAENOIC_ACID_DERIVATIVES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GPX2 Glutathione peroxidase 2 [1] 0.47[2] 0.04[3] -1.60[4] -8.03[5] -8.64[6] 0.61[7]
2 GPX4 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial [8] -0.49[9] 0.15[10] 0.36[11] 0.47[12] -0.37[13] -0.64[14]
3 GPX1 Glutathione peroxidase 1 [15] -0.20[16] -0.29[17] 0.60[18] 0.86[19] 1.39[20] -0.38[21]
4 ALOXE3 Hydroperoxide isomerase ALOXE3 [22] -0.86[23] -2.90[24] -2.56[25] -2.86[26] 1.27[27] [28]
5 ALOX12 Arachidonate 12-lipoxygenase, 12S-type [29] 1.95[30] 2.13[31] 1.61[32] 3.97[33] 2.94[34] 1.98[35]
6 ALOX15 Arachidonate 15-lipoxygenase [36] 2.93[37] -0.90[38] 4.20[39] 1.38[40] 1.38[41] 0.22[42]
7 ALOX12B Arachidonate 12-lipoxygenase, 12R-type [43] [44] [45] [46] [47] [48] [49]

[1]
ref_hepatocyte GPX2
Mean 224
Standard deviation 2.7e+02
Values 61 9.6 19 5.9e+02 4.5e+02
[2]
HepG2 GPX2
Mean 274
Standard deviation 26
Values 2.9e+02 2.6e+02
[3]
HepG2.C3A GPX2
Mean 153
Standard deviation 85
Values 93 2.1e+02
[4]
HuH.7 GPX2
Mean 33.1
Standard deviation 7.7
Values 37 24 38
[5]
SNU475 GPX2
Mean 0.18
Standard deviation 0.025
Values 0.16 0.2
[6]
THLE GPX2
Mean 0.178
Standard deviation 0.026
Values 0.16 0.2
[7]
liver GPX2
Mean 218
Standard deviation 2.6e+02
Values 2.6e+02 30 5.7e+02 6.4
[8]
ref_hepatocyte GPX4
Mean 223
Standard deviation 63
Values 3.1e+02 1.4e+02 2.2e+02 2e+02 2.5e+02
[9]
HepG2 GPX4
Mean 141
Standard deviation 10
Values 1.5e+02 1.3e+02
[10]
HepG2.C3A GPX4
Mean 164
Standard deviation 3.3
Values 1.7e+02 1.6e+02
[11]
HuH.7 GPX4
Mean 128
Standard deviation 29
Values 1.1e+02 1.1e+02 1.6e+02
[12]
SNU475 GPX4
Mean 64.8
Standard deviation 11
Values 73 57
[13]
THLE GPX4
Mean 54.8
Standard deviation 1.7
Values 54 56
[14]
liver GPX4
Mean 91.2
Standard deviation 88
Values 1.7e+02 18 1.6e+02 12
[15]
ref_hepatocyte GPX1
Mean 167
Standard deviation 1e+02
Values 30 1e+02 2.7e+02 2.5e+02 1.8e+02
[16]
HepG2 GPX1
Mean 128
Standard deviation 3.5
Values 1.3e+02 1.3e+02
[17]
HepG2.C3A GPX1
Mean 91.1
Standard deviation 33
Values 67 1.1e+02
[18]
HuH.7 GPX1
Mean 113
Standard deviation 55
Values 1.2e+02 55 1.6e+02
[19]
SNU475 GPX1
Mean 63.3
Standard deviation 6.4
Values 68 59
[20]
THLE GPX1
Mean 139
Standard deviation 16
Values 1.3e+02 1.5e+02
[21]
liver GPX1
Mean 81.8
Standard deviation 69
Values 1.4e+02 25 1.4e+02 19
[22]
ref_hepatocyte ALOXE3
Mean 0.526
Standard deviation 1.2
Values 0 0 2.6 0 0
[23]
HepG2 ALOXE3
Mean 0.257
Standard deviation 0.14
Values 0.36 0.16
[24]
HepG2.C3A ALOXE3
Mean 0.0468
Standard deviation 0.025
Values 0.029 0.064
[25]
HuH.7 ALOXE3
Mean 0.0399
Standard deviation 0.039
Values 0.0082 0.083 0.028
[26]
SNU475 ALOXE3
Mean 0.0152
Standard deviation 0.022
Values 0 0.03
[27]
THLE ALOXE3
Mean 0.401
Standard deviation 0.0024
Values 0.4 0.4
[28]
liver ALOXE3
Mean 0
Standard deviation 0
Values 0 0 0 0
[29]
ref_hepatocyte ALOX12
Mean 0.117
Standard deviation 0.11
Values 0 0 0.18 0.17 0.24
[30]
HepG2 ALOX12
Mean 0.399
Standard deviation 0.13
Values 0.49 0.3
[31]
HepG2.C3A ALOX12
Mean 0.34
Standard deviation 0.041
Values 0.37 0.31
[32]
HuH.7 ALOX12
Mean 0.159
Standard deviation 0.066
Values 0.19 0.21 0.084
[33]
SNU475 ALOX12
Mean 0.384
Standard deviation 0.19
Values 0.52 0.25
[34]
THLE ALOX12
Mean 0.284
Standard deviation 0.025
Values 0.3 0.27
[35]
liver ALOX12
Mean 0.294
Standard deviation 0.18
Values 0.14 0.43 0.13 0.48
[36]
ref_hepatocyte ALOX15
Mean 0.0272
Standard deviation 0.03
Values 0 0 0.019 0.052 0.065
[37]
HepG2 ALOX15
Mean 0.183
Standard deviation 0.19
Values 0.32 0.051
[38]
HepG2.C3A ALOX15
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[39]
HuH.7 ALOX15
Mean 0.223
Standard deviation 0.099
Values 0.27 0.11 0.29
[40]
SNU475 ALOX15
Mean 0.0148
Standard deviation 0.0078
Values 0.0093 0.02
[41]
THLE ALOX15
Mean 0.0225
Standard deviation 0.0017
Values 0.024 0.021
[42]
liver ALOX15
Mean 0.0201
Standard deviation 0.031
Values 0 0.014 0 0.066
[43]
ref_hepatocyte ALOX12B
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[44]
HepG2 ALOX12B
Mean 0.147
Standard deviation 0.051
Values 0.18 0.11
[45]
HepG2.C3A ALOX12B
Mean 0.102
Standard deviation 0.14
Values 0.2 0
[46]
HuH.7 ALOX12B
Mean 0.0922
Standard deviation 0.051
Values 0.082 0.15 0.047
[47]
SNU475 ALOX12B
Mean 0.0196
Standard deviation 0.0081
Values 0.014 0.025
[48]
THLE ALOX12B
Mean 0.0713
Standard deviation 0.033
Values 0.095 0.048
[49]
liver ALOX12B
Mean 0.0118
Standard deviation 0.024
Values 0.047 0 0 0