REACTOME_SUPPRESSION_OF_PHAGOSOMAL_MATURATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.47[2] -0.59[3] -0.69[4] -0.76[5] -0.50[6] -0.02[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] -0.02[16] 0.17[17] -0.32[18] 0.10[19] -0.12[20] 0.43[21]
4 RAB7A Ras-related protein Rab-7a [22] 0.93[23] 0.49[24] 0.44[25] 0.96[26] 1.29[27] 0.55[28]
5 UBA52 Ubiquitin-60S ribosomal protein L40 [29] 2.41[30] 2.40[31] 3.19[32] 1.49[33] 2.11[34] 1.20[35]
6 KPNB1 Importin subunit beta-1 [36] 2.65[37] 2.89[38] 2.92[39] 3.22[40] 2.63[41] 1.31[42]
7 HGS Hepatocyte growth factor-regulated tyrosine kinase substrate [43] 2.63[44] 2.21[45] 1.44[46] 2.52[47] 2.24[48] 1.08[49]
8 RAB5A Ras-related protein Rab-5A [50] 0.86[51] 1.11[52] 1.89[53] 1.78[54] 1.96[55] 1.67[56]
9 ATP6V1H V-type proton ATPase subunit H [57] 1.41[58] 1.38[59] 0.30[60] 2.65[61] 2.35[62] 1.30[63]
10 KPNA1 Importin subunit alpha-5 [64] 2.78[65] 2.92[66] 2.77[67] 3.61[68] 3.71[69] 4.03[70]
11 VPS33B Vacuolar protein sorting-associated protein 33B [71] 2.00[72] 2.18[73] 2.27[74] 2.46[75] 2.10[76] 1.49[77]
12 CORO1A Coronin-1A [78] 2.29[79] 1.95[80] 0.34[81] -0.50[82] 0.01[83] 2.03[84]
13 NOS2 Nitric oxide synthase, inducible [85] 1.75[86] [87] -4.66[88] -2.83[89] -3.92[90] -5.45[91]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte RAB7A
Mean 94.8
Standard deviation 33
Values 83 1.4e+02 1.2e+02 63 69
[23]
HepG2 RAB7A
Mean 120
Standard deviation 5.7
Values 1.2e+02 1.2e+02
[24]
HepG2.C3A RAB7A
Mean 74.7
Standard deviation 5.5
Values 71 79
[25]
HuH.7 RAB7A
Mean 82.4
Standard deviation 5.2
Values 84 77 87
[26]
SNU475 RAB7A
Mean 83
Standard deviation 9.2
Values 90 77
[27]
THLE RAB7A
Mean 135
Standard deviation 27
Values 1.2e+02 1.5e+02
[28]
liver RAB7A
Mean 54.3
Standard deviation 44
Values 90 18 95 14
[29]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[30]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[31]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[32]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[33]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[34]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[35]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[36]
ref_hepatocyte KPNB1
Mean 41.8
Standard deviation 31
Values 59 85 38 12 15
[37]
HepG2 KPNB1
Mean 174
Standard deviation 21
Values 1.6e+02 1.9e+02
[38]
HepG2.C3A KPNB1
Mean 173
Standard deviation 25
Values 1.5e+02 1.9e+02
[39]
HuH.7 KPNB1
Mean 203
Standard deviation 28
Values 2.4e+02 1.9e+02 1.8e+02
[40]
SNU475 KPNB1
Mean 176
Standard deviation 10
Values 1.7e+02 1.8e+02
[41]
THLE KPNB1
Mean 150
Standard deviation 26
Values 1.3e+02 1.7e+02
[42]
liver KPNB1
Mean 40.6
Standard deviation 13
Values 32 58 29 44
[43]
ref_hepatocyte HGS
Mean 16.6
Standard deviation 15
Values 6.9 15 42 11 8.1
[44]
HepG2 HGS
Mean 68.4
Standard deviation 17
Values 80 57
[45]
HepG2.C3A HGS
Mean 43.2
Standard deviation 8
Values 49 38
[46]
HuH.7 HGS
Mean 28.9
Standard deviation 4.1
Values 30 24 32
[47]
SNU475 HGS
Mean 43.1
Standard deviation 3.7
Values 40 46
[48]
THLE HGS
Mean 45.7
Standard deviation 2.6
Values 44 48
[49]
liver HGS
Mean 13.8
Standard deviation 3.3
Values 17 9.3 16 14
[50]
ref_hepatocyte RAB5A
Mean 12.8
Standard deviation 4.6
Values 9.3 19 16 8.8 10
[51]
HepG2 RAB5A
Mean 15.4
Standard deviation 2.7
Values 13 17
[52]
HepG2.C3A RAB5A
Mean 15.5
Standard deviation 1.2
Values 16 15
[53]
HuH.7 RAB5A
Mean 30.3
Standard deviation 3.3
Values 30 34 27
[54]
SNU475 RAB5A
Mean 19.8
Standard deviation 0.012
Values 20 20
[55]
THLE RAB5A
Mean 28.9
Standard deviation 0.86
Values 28 29
[56]
liver RAB5A
Mean 15.9
Standard deviation 6.4
Values 22 11 21 9.6
[57]
ref_hepatocyte ATP6V1H
Mean 9.45
Standard deviation 4.2
Values 11 16 9 6 5.4
[58]
HepG2 ATP6V1H
Mean 16.7
Standard deviation 1.6
Values 16 18
[59]
HepG2.C3A ATP6V1H
Mean 13.8
Standard deviation 1.4
Values 15 13
[60]
HuH.7 ATP6V1H
Mean 7.42
Standard deviation 1.1
Values 6.7 8.7 6.9
[61]
SNU475 ATP6V1H
Mean 26.7
Standard deviation 6.6
Values 31 22
[62]
THLE ATP6V1H
Mean 27.9
Standard deviation 4.7
Values 25 31
[63]
liver ATP6V1H
Mean 9.12
Standard deviation 3.6
Values 13 6.6 11 5.6
[64]
ref_hepatocyte KPNA1
Mean 5.92
Standard deviation 2.1
Values 4.8 9.6 4.9 4.9 5.3
[65]
HepG2 KPNA1
Mean 27.1
Standard deviation 7
Values 22 32
[66]
HepG2.C3A KPNA1
Mean 25.1
Standard deviation 1.6
Values 24 26
[67]
HuH.7 KPNA1
Mean 25.8
Standard deviation 2.3
Values 28 25 24
[68]
SNU475 KPNA1
Mean 32.6
Standard deviation 0.51
Values 32 33
[69]
THLE KPNA1
Mean 45.2
Standard deviation 4
Values 42 48
[70]
liver KPNA1
Mean 38
Standard deviation 4.3
Values 40 36 43 33
[71]
ref_hepatocyte VPS33B
Mean 2.56
Standard deviation 0.54
Values 2.8 2.4 3.2 2.6 1.8
[72]
HepG2 VPS33B
Mean 6.81
Standard deviation 0.25
Values 7 6.6
[73]
HepG2.C3A VPS33B
Mean 6.52
Standard deviation 0.48
Values 6.2 6.9
[74]
HuH.7 VPS33B
Mean 7.9
Standard deviation 0.9
Values 8.5 6.9 8.4
[75]
SNU475 VPS33B
Mean 6.39
Standard deviation 0.43
Values 6.7 6.1
[76]
THLE VPS33B
Mean 6.38
Standard deviation 0.032
Values 6.4 6.4
[77]
liver VPS33B
Mean 2.82
Standard deviation 0.31
Values 3.2 2.7 2.5 2.9
[78]
ref_hepatocyte CORO1A
Mean 2.37
Standard deviation 3.2
Values 0.13 0 0.92 3.1 7.7
[79]
HepG2 CORO1A
Mean 7.69
Standard deviation 2.9
Values 9.8 5.6
[80]
HepG2.C3A CORO1A
Mean 5.13
Standard deviation 0.49
Values 4.8 5.5
[81]
HuH.7 CORO1A
Mean 1.91
Standard deviation 0.67
Values 2 1.2 2.5
[82]
SNU475 CORO1A
Mean 0.756
Standard deviation 0.23
Values 0.59 0.92
[83]
THLE CORO1A
Mean 1.39
Standard deviation 0.24
Values 1.2 1.6
[84]
liver CORO1A
Mean 3.8
Standard deviation 1.3
Values 4.5 2.3 5.2 3.2
[85]
ref_hepatocyte NOS2
Mean 0.74
Standard deviation 1.6
Values 0 0 3.7 0 0.024
[86]
HepG2 NOS2
Mean 1.66
Standard deviation 0.53
Values 1.3 2
[87]
HepG2.C3A NOS2
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 NOS2
Mean 0.0187
Standard deviation 0.017
Values 0.0082 0.039 0.0094
[89]
SNU475 NOS2
Mean 0.0469
Standard deviation 0.027
Values 0.028 0.066
[90]
THLE NOS2
Mean 0.0284
Standard deviation 0.01
Values 0.035 0.021
[91]
liver NOS2
Mean 0.00662
Standard deviation 0.013
Values 0 0 0 0.026