REACTOME_SUMOYLATION_OF_DNA_METHYLATION_PROTEINS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SUMO1 Small ubiquitin-related modifier 1 [1] -1.91[2] -1.61[3] -2.16[4] -1.51[5] -1.83[6] -0.94[7]
2 PHC2 Polyhomeotic-like protein 2 [8] 0.15[9] 0.13[10] -0.45[11] -0.27[12] 0.65[13] -0.07[14]
3 UBE2I SUMO-conjugating enzyme UBC9 [15] 0.98[16] 0.79[17] 0.99[18] 0.29[19] 0.59[20] 0.06[21]
4 RING1 E3 ubiquitin-protein ligase RING1 [22] -0.25[23] -0.39[24] -1.33[25] 0.27[26] -0.57[27] -1.57[28]
5 CBX4 E3 SUMO-protein ligase CBX4 [29] 0.82[30] 0.82[31] 0.49[32] 0.29[33] -0.69[34] -0.80[35]
6 DNMT1 DNA (cytosine-5)-methyltransferase 1 [36] 2.65[37] 2.31[38] 3.01[39] 3.06[40] 3.45[41] 1.69[42]
7 DNMT3A DNA (cytosine-5)-methyltransferase 3A [43] 1.20[44] 1.66[45] 1.37[46] 0.00[47] -0.86[48] 1.13[49]
8 PCGF2 Polycomb group RING finger protein 2 [50] 1.07[51] 0.59[52] 1.00[53] 0.69[54] 0.12[55] -3.00[56]
9 CBX8 Chromobox protein homolog 8 [57] -0.07[58] 0.65[59] 0.26[60] 0.01[61] -1.38[62] -1.48[63]
10 RNF2 E3 ubiquitin-protein ligase RING2 [64] 0.45[65] 1.49[66] 0.74[67] 2.05[68] 0.26[69] 0.96[70]
11 DNMT3B DNA (cytosine-5)-methyltransferase 3B [71] 1.40[72] 0.72[73] 0.12[74] 0.48[75] -1.19[76] -1.36[77]
12 BMI1 Polycomb complex protein BMI-1 [78] -3.01[79] -1.11[80] -2.26[81] -1.00[82] -1.46[83] -0.88[84]
13 SCMH1 Polycomb protein SCMH1 [85] 1.28[86] -1.16[87] 0.65[88] 1.19[89] 1.08[90] 1.70[91]
14 PHC1 Polyhomeotic-like protein 1 [92] 1.21[93] 0.47[94] 0.44[95] 0.72[96] 1.45[97] 0.79[98]
15 PHC3 Polyhomeotic-like protein 3 [99] 1.40[100] 2.76[101] 3.76[102] 2.58[103] 2.82[104] 4.87[105]
16 CBX2 Chromobox protein homolog 2 [106] 3.02[107] 3.09[108] 3.87[109] 2.67[110] 1.38[111] -0.26[112]
[1]
ref_hepatocyte SUMO1
Mean 76.3
Standard deviation 10
Values 80 74 89 61 77
[2]
HepG2 SUMO1
Mean 55.7
Standard deviation 4.2
Values 53 59
[3]
HepG2.C3A SUMO1
Mean 55.2
Standard deviation 14
Values 45 65
[4]
HuH.7 SUMO1
Mean 41.2
Standard deviation 13
Values 44 27 53
[5]
SNU475 SUMO1
Mean 50.5
Standard deviation 16
Values 62 40
[6]
THLE SUMO1
Mean 54.6
Standard deviation 7.9
Values 49 60
[7]
liver SUMO1
Mean 37.2
Standard deviation 30
Values 71 13 54 10
[8]
ref_hepatocyte PHC2
Mean 23.5
Standard deviation 18
Values 3.5 12 47 36 19
[9]
HepG2 PHC2
Mean 71.3
Standard deviation 25
Values 89 54
[10]
HepG2.C3A PHC2
Mean 57
Standard deviation 16
Values 68 46
[11]
HuH.7 PHC2
Mean 41.7
Standard deviation 7.3
Values 43 34 48
[12]
SNU475 PHC2
Mean 36.7
Standard deviation 12
Values 28 45
[13]
THLE PHC2
Mean 93.6
Standard deviation 0.085
Values 94 94
[14]
liver PHC2
Mean 20.8
Standard deviation 5.2
Values 22 20 14 27
[15]
ref_hepatocyte UBE2I
Mean 10.7
Standard deviation 3.4
Values 12 8.6 16 9 7.8
[16]
HepG2 UBE2I
Mean 58
Standard deviation 6.1
Values 62 54
[17]
HepG2.C3A UBE2I
Mean 41.3
Standard deviation 6.2
Values 37 46
[18]
HuH.7 UBE2I
Mean 51.7
Standard deviation 14
Values 57 36 63
[19]
SNU475 UBE2I
Mean 24.7
Standard deviation 1.6
Values 26 24
[20]
THLE UBE2I
Mean 41
Standard deviation 5.6
Values 37 45
[21]
liver UBE2I
Mean 10.4
Standard deviation 6.3
Values 16 5.3 15 4.7
[22]
ref_hepatocyte RING1
Mean 10.6
Standard deviation 6.2
Values 5.4 4.1 9.4 17 17
[23]
HepG2 RING1
Mean 24.7
Standard deviation 0.26
Values 24 25
[24]
HepG2.C3A RING1
Mean 18
Standard deviation 2.2
Values 20 16
[25]
HuH.7 RING1
Mean 10.3
Standard deviation 2.1
Values 10 8.4 12
[26]
SNU475 RING1
Mean 24.3
Standard deviation 1.5
Values 25 23
[27]
THLE RING1
Mean 18.2
Standard deviation 1.5
Values 19 17
[28]
liver RING1
Mean 3.35
Standard deviation 1
Values 3.6 4 1.8 3.9
[29]
ref_hepatocyte CBX4
Mean 6.6
Standard deviation 4.2
Values 11 1.3 9.7 7.6 3.2
[30]
HepG2 CBX4
Mean 32
Standard deviation 12
Values 40 24
[31]
HepG2.C3A CBX4
Mean 25.8
Standard deviation 11
Values 33 18
[32]
HuH.7 CBX4
Mean 22.4
Standard deviation 1.6
Values 21 24 22
[33]
SNU475 CBX4
Mean 15.2
Standard deviation 0.71
Values 15 16
[34]
THLE CBX4
Mean 10.4
Standard deviation 0.58
Values 11 9.9
[35]
liver CBX4
Mean 3.54
Standard deviation 1.8
Values 5.8 4.1 1.8 2.5
[36]
ref_hepatocyte DNMT1
Mean 3.28
Standard deviation 1.4
Values 5.2 3.9 3.3 2.4 1.6
[37]
HepG2 DNMT1
Mean 56.5
Standard deviation 6.2
Values 52 61
[38]
HepG2.C3A DNMT1
Mean 36.1
Standard deviation 9.3
Values 30 43
[39]
HuH.7 DNMT1
Mean 63.9
Standard deviation 30
Values 86 30 76
[40]
SNU475 DNMT1
Mean 51.7
Standard deviation 9.8
Values 45 59
[41]
THLE DNMT1
Mean 91.2
Standard deviation 13
Values 82 1e+02
[42]
liver DNMT1
Mean 9.87
Standard deviation 1
Values 8.6 11 11 9.5
[43]
ref_hepatocyte DNMT3A
Mean 2.8
Standard deviation 3.3
Values 8.7 1.7 1.1 1.2 1.3
[44]
HepG2 DNMT3A
Mean 17.7
Standard deviation 0.61
Values 18 17
[45]
HepG2.C3A DNMT3A
Mean 19.7
Standard deviation 0.75
Values 19 20
[46]
HuH.7 DNMT3A
Mean 17.6
Standard deviation 2.3
Values 20 16 16
[47]
SNU475 DNMT3A
Mean 5.28
Standard deviation 2.5
Values 7 3.5
[48]
THLE DNMT3A
Mean 3.91
Standard deviation 0.33
Values 3.7 4.1
[49]
liver DNMT3A
Mean 5.72
Standard deviation 1.9
Values 6.5 6.3 3 7.1
[50]
ref_hepatocyte PCGF2
Mean 2.76
Standard deviation 5
Values 12 1 0.52 0.41 0.16
[51]
HepG2 PCGF2
Mean 15.9
Standard deviation 1.3
Values 17 15
[52]
HepG2.C3A PCGF2
Mean 9.24
Standard deviation 0.82
Values 9.8 8.7
[53]
HuH.7 PCGF2
Mean 13.3
Standard deviation 0.79
Values 14 13 13
[54]
SNU475 PCGF2
Mean 8.37
Standard deviation 0.75
Values 7.8 8.9
[55]
THLE PCGF2
Mean 7.62
Standard deviation 0.67
Values 7.1 8.1
[56]
liver PCGF2
Mean 0.321
Standard deviation 0.045
Values 0.28 0.3 0.39 0.32
[57]
ref_hepatocyte CBX8
Mean 2.49
Standard deviation 3.3
Values 8.2 0.84 0 2.1 1.3
[58]
HepG2 CBX8
Mean 6.5
Standard deviation 0.058
Values 6.5 6.5
[59]
HepG2.C3A CBX8
Mean 8.66
Standard deviation 1
Values 9.4 7.9
[60]
HuH.7 CBX8
Mean 7.19
Standard deviation 0.48
Values 7.2 6.7 7.7
[61]
SNU475 CBX8
Mean 4.74
Standard deviation 0.38
Values 5 4.5
[62]
THLE CBX8
Mean 2.42
Standard deviation 0.13
Values 2.3 2.5
[63]
liver CBX8
Mean 0.832
Standard deviation 0.3
Values 0.8 0.71 1.3 0.56
[64]
ref_hepatocyte RNF2
Mean 2.37
Standard deviation 1.4
Values 2.5 1.7 4.8 1.4 1.4
[65]
HepG2 RNF2
Mean 8.92
Standard deviation 1.7
Values 7.7 10
[66]
HepG2.C3A RNF2
Mean 14.8
Standard deviation 3.4
Values 12 17
[67]
HuH.7 RNF2
Mean 9.56
Standard deviation 0.85
Values 9.9 10 8.6
[68]
SNU475 RNF2
Mean 18.5
Standard deviation 0.79
Values 18 19
[69]
THLE RNF2
Mean 7.19
Standard deviation 0.95
Values 6.5 7.9
[70]
liver RNF2
Mean 4.29
Standard deviation 0.53
Values 4.8 4.5 4.3 3.5
[71]
ref_hepatocyte DNMT3B
Mean 2.35
Standard deviation 2
Values 3.6 1.1 5 0.1 2
[72]
HepG2 DNMT3B
Mean 17.1
Standard deviation 1.1
Values 18 16
[73]
HepG2.C3A DNMT3B
Mean 8.62
Standard deviation 2.8
Values 6.6 11
[74]
HuH.7 DNMT3B
Mean 6.18
Standard deviation 2.5
Values 7.8 3.3 7.4
[75]
SNU475 DNMT3B
Mean 6.2
Standard deviation 1.4
Values 7.2 5.2
[76]
THLE DNMT3B
Mean 2.63
Standard deviation 0.35
Values 2.4 2.9
[77]
liver DNMT3B
Mean 0.855
Standard deviation 0.27
Values 0.54 0.77 1.2 0.93
[78]
ref_hepatocyte BMI1
Mean 2.28
Standard deviation 2.2
Values 4.3 5 1.3 0.41 0.36
[79]
HepG2 BMI1
Mean 0.777
Standard deviation 0.22
Values 0.62 0.94
[80]
HepG2.C3A BMI1
Mean 2.34
Standard deviation 0.86
Values 1.7 2.9
[81]
HuH.7 BMI1
Mean 1.16
Standard deviation 0.55
Values 1.1 1.7 0.64
[82]
SNU475 BMI1
Mean 2.15
Standard deviation 0.41
Values 2.4 1.9
[83]
THLE BMI1
Mean 2.11
Standard deviation 0.14
Values 2.2 2
[84]
liver BMI1
Mean 1.16
Standard deviation 1
Values 0.21 2.2 0.36 1.8
[85]
ref_hepatocyte SCMH1
Mean 2.28
Standard deviation 0.67
Values 2 1.8 2.7 3.3 1.7
[86]
HepG2 SCMH1
Mean 15.2
Standard deviation 1.5
Values 14 16
[87]
HepG2.C3A SCMH1
Mean 2.27
Standard deviation 0.42
Values 2.6 2
[88]
HuH.7 SCMH1
Mean 8.63
Standard deviation 0.61
Values 9.3 8.5 8.1
[89]
SNU475 SCMH1
Mean 9.83
Standard deviation 2.9
Values 12 7.8
[90]
THLE SCMH1
Mean 12.2
Standard deviation 0.37
Values 12 12
[91]
liver SCMH1
Mean 6.91
Standard deviation 0.79
Values 8 7 6.3 6.4
[92]
ref_hepatocyte PHC1
Mean 1.73
Standard deviation 1.3
Values 1.7 0.54 3.8 0.72 1.8
[93]
HepG2 PHC1
Mean 11
Standard deviation 3.2
Values 13 8.7
[94]
HepG2.C3A PHC1
Mean 5.31
Standard deviation 1.4
Values 6.3 4.3
[95]
HuH.7 PHC1
Mean 5.67
Standard deviation 1.2
Values 5.8 6.9 4.4
[96]
SNU475 PHC1
Mean 5.34
Standard deviation 0.47
Values 5.7 5
[97]
THLE PHC1
Mean 12
Standard deviation 0.55
Values 12 12
[98]
liver PHC1
Mean 2.78
Standard deviation 0.77
Values 3.7 2.2 3.1 2.1
[99]
ref_hepatocyte PHC3
Mean 1.21
Standard deviation 0.51
Values 1.7 1.8 1.1 0.54 1
[100]
HepG2 PHC3
Mean 8.8
Standard deviation 3
Values 6.6 11
[101]
HepG2.C3A PHC3
Mean 18.2
Standard deviation 1.1
Values 19 17
[102]
HuH.7 PHC3
Mean 39.7
Standard deviation 17
Values 37 57 24
[103]
SNU475 PHC3
Mean 13.7
Standard deviation 1.9
Values 15 12
[104]
THLE PHC3
Mean 21.7
Standard deviation 1.4
Values 23 21
[105]
liver PHC3
Mean 33.1
Standard deviation 11
Values 24 44 23 41
[106]
ref_hepatocyte CBX2
Mean 0.789
Standard deviation 1.1
Values 2.7 0.054 0.91 0 0.27
[107]
HepG2 CBX2
Mean 17.6
Standard deviation 3.1
Values 20 15
[108]
HepG2.C3A CBX2
Mean 14.9
Standard deviation 0.24
Values 15 15
[109]
HuH.7 CBX2
Mean 28
Standard deviation 11
Values 37 15 31
[110]
SNU475 CBX2
Mean 9.46
Standard deviation 0.74
Values 10 8.9
[111]
THLE CBX2
Mean 5.2
Standard deviation 0.14
Values 5.1 5.3
[112]
liver CBX2
Mean 0.615
Standard deviation 0.18
Values 0.71 0.61 0.77 0.37