REACTOME_SULFUR_AMINO_ACID_METABOLISM | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | MAT1A | S-adenosylmethionine synthase isoform type-1 | [1] | -1.92[2] | -0.62[3] | -2.51[4] | -7.69[5] | -10.27[6] | 0.79[7] |
2 | ADI1 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase | [8] | -1.17[9] | -1.72[10] | -2.30[11] | -0.74[12] | -0.33[13] | -0.16[14] |
3 | TST | Thiosulfate sulfurtransferase | [15] | -2.78[16] | -2.12[17] | -1.52[18] | -4.13[19] | -3.33[20] | -1.48[21] |
4 | BHMT | Betaine--homocysteine S-methyltransferase 1 | [22] | -4.59[23] | -5.34[24] | -9.18[25] | -6.78[26] | -13.63[27] | -0.96[28] |
5 | MPST | 3-mercaptopyruvate sulfurtransferase | [29] | -0.12[30] | 0.10[31] | 0.36[32] | -1.98[33] | -1.59[34] | -0.68[35] |
6 | GOT1 | Aspartate aminotransferase, cytoplasmic | [36] | 0.29[37] | 1.36[38] | -0.16[39] | -1.08[40] | -0.22[41] | 0.25[42] |
7 | AHCY | Adenosylhomocysteinase | [43] | 2.58[44] | 2.43[45] | 2.69[46] | 1.98[47] | 1.48[48] | -1.16[49] |
8 | CDO1 | Cysteine dioxygenase type 1 | [50] | -4.66[51] | -6.79[52] | -4.79[53] | -5.57[54] | -10.93[55] | -0.28[56] |
9 | BHMT2 | S-methylmethionine--homocysteine S-methyltransferase BHMT2 | [57] | -1.75[58] | -1.59[59] | -0.96[60] | 1.59[61] | -6.16[62] | 0.99[63] |
10 | GOT2 | Aspartate aminotransferase, mitochondrial | [64] | 1.18[65] | 0.16[66] | 0.38[67] | 1.01[68] | 2.00[69] | 0.57[70] |
11 | CBS | Cystathionine beta-synthase | [71] | 0.10[72] | -0.26[73] | 1.33[74] | -0.87[75] | 0.57[76] | 0.81[77] |
12 | TXN2 | Thioredoxin, mitochondrial | [78] | 0.35[79] | -0.05[80] | 0.29[81] | 0.44[82] | 0.42[83] | -0.73[84] |
13 | TSTD1 | Thiosulfate:glutathione sulfurtransferase | [85] | -12.09[86] | -9.69[87] | -10.53[88] | -1.39[89] | -0.98[90] | -2.23[91] |
14 | CTH | Cystathionine gamma-lyase | [92] | -0.83[93] | -2.16[94] | -0.24[95] | -1.85[96] | -1.41[97] | -0.21[98] |
15 | SLC25A10 | Mitochondrial dicarboxylate carrier | [99] | 2.20[100] | 1.42[101] | -0.24[102] | 0.78[103] | 1.13[104] | -0.65[105] |
16 | APIP | Methylthioribulose-1-phosphate dehydratase | [106] | -0.08[107] | 0.06[108] | 0.31[109] | 1.21[110] | 0.62[111] | -1.37[112] |
17 | SUOX | Sulfite oxidase, mitochondrial | [113] | -0.31[114] | 0.03[115] | 0.16[116] | 0.64[117] | 0.18[118] | -0.01[119] |
18 | ETHE1 | Persulfide dioxygenase ETHE1, mitochondrial | [120] | 0.23[121] | 0.94[122] | 1.37[123] | -0.08[124] | 1.15[125] | -0.95[126] |
19 | ENOPH1 | Enolase-phosphatase E1 | [127] | 1.89[128] | 1.93[129] | 1.63[130] | 2.09[131] | 2.51[132] | -1.05[133] |
20 | CSAD | Cysteine sulfinic acid decarboxylase | [134] | -1.11[135] | 0.09[136] | -0.73[137] | 0.89[138] | 0.45[139] | 0.49[140] |
21 | MTRR | Methionine synthase reductase | [141] | 1.82[142] | 1.91[143] | 2.67[144] | 3.31[145] | 3.91[146] | 1.07[147] |
22 | MTAP | S-methyl-5'-thioadenosine phosphorylase | [148] | 2.36[149] | 1.45[150] | 1.68[151] | 3.40[152] | 3.67[153] | 0.40[154] |
23 | MRI1 | Methylthioribose-1-phosphate isomerase | [155] | 2.07[156] | 1.63[157] | 2.83[158] | 2.62[159] | 3.14[160] | 0.97[161] |
24 | ADO | 2-aminoethanethiol dioxygenase | [162] | 3.21[163] | 2.84[164] | 2.13[165] | 4.49[166] | 4.55[167] | 0.04[168] |
25 | MTR | Methionine synthase | [169] | 3.86[170] | 3.97[171] | 4.15[172] | 5.90[173] | 5.17[174] | 3.21[175] |
26 | SQOR | Sulfide:quinone oxidoreductase, mitochondrial | [176] | [177] | [178] | [179] | [180] | [181] | [182] |
27 | CBSL | Cystathionine beta-synthase-like protein | [183] | [184] | [185] | [186] | [187] | [188] | [189] |
28 | GADL1 | Acidic amino acid decarboxylase GADL1 | [190] | [191] | [192] | [193] | [194] | [195] | [196] |