REACTOME_BETA_DEFENSINS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 DEFB1 Beta-defensin 1 [1] -0.35[2] -0.99[3] -2.64[4] -5.57[5] -10.83[6] -1.59[7]
2 TLR2 Toll-like receptor 2 [8] -1.43[9] -0.04[10] -7.75[11] 0.28[12] 3.53[13] 2.44[14]
3 DEFB4B [15] [16] [17] [18] [19] [20] [21]
4 DEFB103B [22] [23] [24] [25] [26] [27] [28]
5 TLR1 Toll-like receptor 1 [29] -1.25[30] [31] -5.64[32] 4.86[33] 2.54[34] 3.26[35]
6 CCR2 C-C chemokine receptor type 2 [36] [37] [38] 1.10[39] [40] [41] 2.06[42]
7 CCR6 C-C chemokine receptor type 6 [43] 4.33[44] 4.95[45] 5.60[46] 3.76[47] -0.38[48] 0.89[49]
8 DEFB132 Beta-defensin 132 [50] [51] [52] [53] [54] [55] 0.83[56]
9 DEFB106A Beta-defensin 106 [57] [58] [59] [60] [61] [62] [63]
10 DEFB110 Beta-defensin 110 [64] [65] [66] [67] [68] [69] [70]
11 DEFB119 Beta-defensin 119 [71] [72] [73] [74] [75] [76] [77]
12 DEFB104B [78] [79] [80] [81] [82] [83] [84]
13 DEFB103A Beta-defensin 103 [85] [86] [87] [88] [89] [90] [91]
14 DEFB130B Beta-defensin 130B [92] [93] [94] [95] [96] [97] [98]
15 DEFB108B Beta-defensin 108B [99] [100] [101] [102] [103] [104] [105]
16 DEFB129 Beta-defensin 129 [106] [107] [108] [109] [110] [111] [112]
17 DEFB105B [113] [114] [115] [116] [117] [118] [119]
18 DEFB126 Beta-defensin 126 [120] [121] [122] [123] [124] [125] [126]
19 DEFB136 Beta-defensin 136 [127] [128] [129] [130] [131] [132] [133]
20 DEFB112 Beta-defensin 112 [134] [135] [136] [137] [138] [139] [140]
21 DEFB116 Beta-defensin 116 [141] [142] [143] [144] [145] [146] [147]
22 DEFB107B [148] [149] [150] [151] [152] [153] [154]
23 DEFB113 Beta-defensin 113 [155] [156] [157] [158] [159] [160] [161]
24 DEFB133 Beta-defensin 133 [162] [163] [164] [165] [166] [167] [168]
25 DEFB123 Beta-defensin 123 [169] [170] [171] [172] [173] [174] [175]
26 DEFB121 Beta-defensin 121 [176] [177] [178] [179] [180] [181] [182]
27 DEFB135 Beta-defensin 135 [183] [184] [185] [186] [187] [188] [189]
28 DEFB128 Beta-defensin 128 [190] [191] [192] [193] [194] [195] [196]
29 DEFB114 Beta-defensin 114 [197] [198] [199] [200] [201] [202] [203]
30 DEFB125 Beta-defensin 125 [204] [205] [206] [207] [208] [209] [210]
31 DEFB118 Beta-defensin 118 [211] [212] [213] [214] [215] [216] [217]
32 DEFB124 Beta-defensin 124 [218] [219] [220] [221] [222] [223] [224]
33 DEFB107A Beta-defensin 107 [225] [226] [227] [228] [229] [230] [231]
34 DEFB115 Beta-defensin 115 [232] [233] [234] [235] [236] [237] [238]
35 DEFB134 Beta-defensin 134 [239] [240] [241] [242] [243] [244] [245]
36 DEFB131A Beta-defensin 131A [246] [247] [248] [249] [250] [251] [252]
37 DEFB4A Beta-defensin 4A [253] [254] [255] [256] [257] [258] [259]
38 DEFB105A Beta-defensin 105 [260] [261] [262] [263] [264] [265] [266]
39 DEFB130A Beta-defensin 130A [267] [268] [269] [270] [271] [272] [273]
40 DEFB104A Beta-defensin 104 [274] [275] [276] [277] [278] [279] [280]
41 DEFB127 Beta-defensin 127 [281] [282] [283] [284] [285] [286] [287]
42 DEFB106B [288] [289] [290] [291] [292] [293] [294]

[1]
ref_hepatocyte DEFB1
Mean 16.7
Standard deviation 15
Values 0 4.5 15 33 31
[2]
HepG2 DEFB1
Mean 6.68
Standard deviation 2
Values 8.1 5.2
[3]
HepG2.C3A DEFB1
Mean 3.9
Standard deviation 1.9
Values 2.6 5.2
[4]
HuH.7 DEFB1
Mean 1.95
Standard deviation 0.6
Values 2 1.3 2.5
[5]
SNU475 DEFB1
Mean 0.0169
Standard deviation 0.0024
Values 0.019 0.015
[6]
THLE DEFB1
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[7]
liver DEFB1
Mean 3.43
Standard deviation 4.2
Values 8.6 0.11 5.1 0
[8]
ref_hepatocyte TLR2
Mean 1.56
Standard deviation 1.2
Values 0 0.96 2.3 3.1 1.4
[9]
HepG2 TLR2
Mean 0.296
Standard deviation 0.084
Values 0.36 0.24
[10]
HepG2.C3A TLR2
Mean 0.704
Standard deviation 0.0056
Values 0.7 0.71
[11]
HuH.7 TLR2
Mean 0.00526
Standard deviation 0.0048
Values 0 0.0064 0.0094
[12]
SNU475 TLR2
Mean 0.0914
Standard deviation 0.057
Values 0.051 0.13
[13]
THLE TLR2
Mean 11.1
Standard deviation 4.3
Values 14 8.1
[14]
liver TLR2
Mean 5.26
Standard deviation 1.6
Values 3.2 6.8 5.1 5.9
[15]
ref_hepatocyte DEFB4B
Mean 1.01
Standard deviation 2.3
Values 0 0 5.1 0 0
[16]
HepG2 DEFB4B
Missing
[17]
HepG2.C3A DEFB4B
Missing
[18]
HuH.7 DEFB4B
Missing
[19]
SNU475 DEFB4B
Missing
[20]
THLE DEFB4B
Missing
[21]
liver DEFB4B
Missing
[22]
ref_hepatocyte DEFB103B
Mean 0.568
Standard deviation 1.3
Values 0 0 2.8 0 0
[23]
HepG2 DEFB103B
Missing
[24]
HepG2.C3A DEFB103B
Missing
[25]
HuH.7 DEFB103B
Missing
[26]
SNU475 DEFB103B
Missing
[27]
THLE DEFB103B
Missing
[28]
liver DEFB103B
Missing
[29]
ref_hepatocyte TLR1
Mean 0.481
Standard deviation 0.24
Values 0.12 0.52 0.38 0.69 0.7
[30]
HepG2 TLR1
Mean 0.103
Standard deviation 0.024
Values 0.12 0.086
[31]
HepG2.C3A TLR1
Mean 0
Standard deviation 0
Values 0 0
[32]
HuH.7 TLR1
Mean 0.00701
Standard deviation 0.0065
Values 0.0082 0.013 0
[33]
SNU475 TLR1
Mean 0.672
Standard deviation 0.026
Values 0.69 0.65
[34]
THLE TLR1
Mean 1.71
Standard deviation 0.1
Values 1.8 1.6
[35]
liver TLR1
Mean 2.86
Standard deviation 1.1
Values 2 4.4 2.1 3
[36]
ref_hepatocyte CCR2
Mean 0.423
Standard deviation 0.8
Values 0 0.044 0 0.22 1.9
[37]
HepG2 CCR2
Mean 0
Standard deviation 0
Values 0 0
[38]
HepG2.C3A CCR2
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 CCR2
Mean 0.659
Standard deviation 0.53
Values 0.5 1.3 0.22
[40]
SNU475 CCR2
Mean 0
Standard deviation 0
Values 0 0
[41]
THLE CCR2
Mean 0
Standard deviation 0
Values 0 0
[42]
liver CCR2
Mean 1.09
Standard deviation 0.48
Values 1.5 0.77 0.59 1.5
[43]
ref_hepatocyte CCR6
Mean 0.363
Standard deviation 0.58
Values 1.4 0.16 0.033 0.14 0.081
[44]
HepG2 CCR6
Mean 3.72
Standard deviation 0.62
Values 3.3 4.2
[45]
HepG2.C3A CCR6
Mean 5.21
Standard deviation 1.6
Values 4.1 6.3
[46]
HuH.7 CCR6
Mean 12.8
Standard deviation 4.7
Values 15 7.3 16
[47]
SNU475 CCR6
Mean 0.236
Standard deviation 0.12
Values 0.15 0.32
[48]
THLE CCR6
Mean 0.171
Standard deviation 0.068
Values 0.22 0.12
[49]
liver CCR6
Mean 0.417
Standard deviation 0.15
Values 0.49 0.43 0.21 0.54
[50]
ref_hepatocyte DEFB132
Mean 0.0723
Standard deviation 0.1
Values 0 0 0 0.21 0.15
[51]
HepG2 DEFB132
Mean 0
Standard deviation 0
Values 0 0
[52]
HepG2.C3A DEFB132
Mean 0
Standard deviation 0
Values 0 0
[53]
HuH.7 DEFB132
Mean 0
Standard deviation 0
Values 0 0 0
[54]
SNU475 DEFB132
Mean 0
Standard deviation 0
Values 0 0
[55]
THLE DEFB132
Mean 0
Standard deviation 0
Values 0 0
[56]
liver DEFB132
Mean 0.0796
Standard deviation 0.095
Values 0 0.1 0.21 0.013
[57]
ref_hepatocyte DEFB106A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[58]
HepG2 DEFB106A
Missing
[59]
HepG2.C3A DEFB106A
Missing
[60]
HuH.7 DEFB106A
Missing
[61]
SNU475 DEFB106A
Missing
[62]
THLE DEFB106A
Missing
[63]
liver DEFB106A
Missing
[64]
ref_hepatocyte DEFB110
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 DEFB110
Missing
[66]
HepG2.C3A DEFB110
Missing
[67]
HuH.7 DEFB110
Missing
[68]
SNU475 DEFB110
Missing
[69]
THLE DEFB110
Missing
[70]
liver DEFB110
Missing
[71]
ref_hepatocyte DEFB119
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[72]
HepG2 DEFB119
Missing
[73]
HepG2.C3A DEFB119
Missing
[74]
HuH.7 DEFB119
Missing
[75]
SNU475 DEFB119
Missing
[76]
THLE DEFB119
Missing
[77]
liver DEFB119
Missing
[78]
ref_hepatocyte DEFB104B
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 DEFB104B
Missing
[80]
HepG2.C3A DEFB104B
Missing
[81]
HuH.7 DEFB104B
Missing
[82]
SNU475 DEFB104B
Missing
[83]
THLE DEFB104B
Missing
[84]
liver DEFB104B
Missing
[85]
ref_hepatocyte DEFB103A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 DEFB103A
Missing
[87]
HepG2.C3A DEFB103A
Missing
[88]
HuH.7 DEFB103A
Missing
[89]
SNU475 DEFB103A
Missing
[90]
THLE DEFB103A
Missing
[91]
liver DEFB103A
Missing
[92]
ref_hepatocyte DEFB130B
Missing
[93]
HepG2 DEFB130B
Missing
[94]
HepG2.C3A DEFB130B
Missing
[95]
HuH.7 DEFB130B
Missing
[96]
SNU475 DEFB130B
Missing
[97]
THLE DEFB130B
Missing
[98]
liver DEFB130B
Missing
[99]
ref_hepatocyte DEFB108B
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[100]
HepG2 DEFB108B
Missing
[101]
HepG2.C3A DEFB108B
Missing
[102]
HuH.7 DEFB108B
Missing
[103]
SNU475 DEFB108B
Missing
[104]
THLE DEFB108B
Missing
[105]
liver DEFB108B
Missing
[106]
ref_hepatocyte DEFB129
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[107]
HepG2 DEFB129
Missing
[108]
HepG2.C3A DEFB129
Missing
[109]
HuH.7 DEFB129
Missing
[110]
SNU475 DEFB129
Missing
[111]
THLE DEFB129
Missing
[112]
liver DEFB129
Missing
[113]
ref_hepatocyte DEFB105B
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[114]
HepG2 DEFB105B
Missing
[115]
HepG2.C3A DEFB105B
Missing
[116]
HuH.7 DEFB105B
Missing
[117]
SNU475 DEFB105B
Missing
[118]
THLE DEFB105B
Missing
[119]
liver DEFB105B
Missing
[120]
ref_hepatocyte DEFB126
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[121]
HepG2 DEFB126
Missing
[122]
HepG2.C3A DEFB126
Missing
[123]
HuH.7 DEFB126
Missing
[124]
SNU475 DEFB126
Missing
[125]
THLE DEFB126
Missing
[126]
liver DEFB126
Missing
[127]
ref_hepatocyte DEFB136
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[128]
HepG2 DEFB136
Missing
[129]
HepG2.C3A DEFB136
Missing
[130]
HuH.7 DEFB136
Missing
[131]
SNU475 DEFB136
Missing
[132]
THLE DEFB136
Missing
[133]
liver DEFB136
Missing
[134]
ref_hepatocyte DEFB112
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[135]
HepG2 DEFB112
Missing
[136]
HepG2.C3A DEFB112
Missing
[137]
HuH.7 DEFB112
Missing
[138]
SNU475 DEFB112
Missing
[139]
THLE DEFB112
Missing
[140]
liver DEFB112
Missing
[141]
ref_hepatocyte DEFB116
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 DEFB116
Missing
[143]
HepG2.C3A DEFB116
Missing
[144]
HuH.7 DEFB116
Missing
[145]
SNU475 DEFB116
Missing
[146]
THLE DEFB116
Missing
[147]
liver DEFB116
Missing
[148]
ref_hepatocyte DEFB107B
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[149]
HepG2 DEFB107B
Missing
[150]
HepG2.C3A DEFB107B
Missing
[151]
HuH.7 DEFB107B
Missing
[152]
SNU475 DEFB107B
Missing
[153]
THLE DEFB107B
Missing
[154]
liver DEFB107B
Missing
[155]
ref_hepatocyte DEFB113
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[156]
HepG2 DEFB113
Missing
[157]
HepG2.C3A DEFB113
Missing
[158]
HuH.7 DEFB113
Missing
[159]
SNU475 DEFB113
Missing
[160]
THLE DEFB113
Missing
[161]
liver DEFB113
Missing
[162]
ref_hepatocyte DEFB133
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[163]
HepG2 DEFB133
Mean 0
Standard deviation 0
Values 0 0
[164]
HepG2.C3A DEFB133
Mean 0
Standard deviation 0
Values 0 0
[165]
HuH.7 DEFB133
Mean 0.008
Standard deviation 0.0015
Values 0.0082 0.0064 0.0094
[166]
SNU475 DEFB133
Mean 0
Standard deviation 0
Values 0 0
[167]
THLE DEFB133
Mean 0
Standard deviation 0
Values 0 0
[168]
liver DEFB133
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[169]
ref_hepatocyte DEFB123
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[170]
HepG2 DEFB123
Missing
[171]
HepG2.C3A DEFB123
Missing
[172]
HuH.7 DEFB123
Missing
[173]
SNU475 DEFB123
Missing
[174]
THLE DEFB123
Missing
[175]
liver DEFB123
Missing
[176]
ref_hepatocyte DEFB121
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[177]
HepG2 DEFB121
Missing
[178]
HepG2.C3A DEFB121
Missing
[179]
HuH.7 DEFB121
Missing
[180]
SNU475 DEFB121
Missing
[181]
THLE DEFB121
Missing
[182]
liver DEFB121
Missing
[183]
ref_hepatocyte DEFB135
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[184]
HepG2 DEFB135
Missing
[185]
HepG2.C3A DEFB135
Missing
[186]
HuH.7 DEFB135
Missing
[187]
SNU475 DEFB135
Missing
[188]
THLE DEFB135
Missing
[189]
liver DEFB135
Missing
[190]
ref_hepatocyte DEFB128
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[191]
HepG2 DEFB128
Missing
[192]
HepG2.C3A DEFB128
Missing
[193]
HuH.7 DEFB128
Missing
[194]
SNU475 DEFB128
Missing
[195]
THLE DEFB128
Missing
[196]
liver DEFB128
Missing
[197]
ref_hepatocyte DEFB114
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[198]
HepG2 DEFB114
Missing
[199]
HepG2.C3A DEFB114
Missing
[200]
HuH.7 DEFB114
Missing
[201]
SNU475 DEFB114
Missing
[202]
THLE DEFB114
Missing
[203]
liver DEFB114
Missing
[204]
ref_hepatocyte DEFB125
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[205]
HepG2 DEFB125
Missing
[206]
HepG2.C3A DEFB125
Missing
[207]
HuH.7 DEFB125
Missing
[208]
SNU475 DEFB125
Missing
[209]
THLE DEFB125
Missing
[210]
liver DEFB125
Missing
[211]
ref_hepatocyte DEFB118
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[212]
HepG2 DEFB118
Missing
[213]
HepG2.C3A DEFB118
Missing
[214]
HuH.7 DEFB118
Missing
[215]
SNU475 DEFB118
Missing
[216]
THLE DEFB118
Missing
[217]
liver DEFB118
Missing
[218]
ref_hepatocyte DEFB124
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[219]
HepG2 DEFB124
Missing
[220]
HepG2.C3A DEFB124
Missing
[221]
HuH.7 DEFB124
Missing
[222]
SNU475 DEFB124
Missing
[223]
THLE DEFB124
Missing
[224]
liver DEFB124
Missing
[225]
ref_hepatocyte DEFB107A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[226]
HepG2 DEFB107A
Missing
[227]
HepG2.C3A DEFB107A
Missing
[228]
HuH.7 DEFB107A
Missing
[229]
SNU475 DEFB107A
Missing
[230]
THLE DEFB107A
Missing
[231]
liver DEFB107A
Missing
[232]
ref_hepatocyte DEFB115
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[233]
HepG2 DEFB115
Mean 0
Standard deviation 0
Values 0 0
[234]
HepG2.C3A DEFB115
Mean 0
Standard deviation 0
Values 0 0
[235]
HuH.7 DEFB115
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[236]
SNU475 DEFB115
Mean 0
Standard deviation 0
Values 0 0
[237]
THLE DEFB115
Mean 0
Standard deviation 0
Values 0 0
[238]
liver DEFB115
Mean 0
Standard deviation 0
Values 0 0 0 0
[239]
ref_hepatocyte DEFB134
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[240]
HepG2 DEFB134
Missing
[241]
HepG2.C3A DEFB134
Missing
[242]
HuH.7 DEFB134
Missing
[243]
SNU475 DEFB134
Missing
[244]
THLE DEFB134
Missing
[245]
liver DEFB134
Missing
[246]
ref_hepatocyte DEFB131A
Missing
[247]
HepG2 DEFB131A
Missing
[248]
HepG2.C3A DEFB131A
Missing
[249]
HuH.7 DEFB131A
Missing
[250]
SNU475 DEFB131A
Missing
[251]
THLE DEFB131A
Missing
[252]
liver DEFB131A
Missing
[253]
ref_hepatocyte DEFB4A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[254]
HepG2 DEFB4A
Missing
[255]
HepG2.C3A DEFB4A
Missing
[256]
HuH.7 DEFB4A
Missing
[257]
SNU475 DEFB4A
Missing
[258]
THLE DEFB4A
Missing
[259]
liver DEFB4A
Missing
[260]
ref_hepatocyte DEFB105A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[261]
HepG2 DEFB105A
Missing
[262]
HepG2.C3A DEFB105A
Missing
[263]
HuH.7 DEFB105A
Missing
[264]
SNU475 DEFB105A
Missing
[265]
THLE DEFB105A
Missing
[266]
liver DEFB105A
Missing
[267]
ref_hepatocyte DEFB130A
Missing
[268]
HepG2 DEFB130A
Missing
[269]
HepG2.C3A DEFB130A
Missing
[270]
HuH.7 DEFB130A
Missing
[271]
SNU475 DEFB130A
Missing
[272]
THLE DEFB130A
Missing
[273]
liver DEFB130A
Missing
[274]
ref_hepatocyte DEFB104A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[275]
HepG2 DEFB104A
Missing
[276]
HepG2.C3A DEFB104A
Missing
[277]
HuH.7 DEFB104A
Missing
[278]
SNU475 DEFB104A
Missing
[279]
THLE DEFB104A
Missing
[280]
liver DEFB104A
Missing
[281]
ref_hepatocyte DEFB127
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[282]
HepG2 DEFB127
Missing
[283]
HepG2.C3A DEFB127
Missing
[284]
HuH.7 DEFB127
Missing
[285]
SNU475 DEFB127
Missing
[286]
THLE DEFB127
Missing
[287]
liver DEFB127
Missing
[288]
ref_hepatocyte DEFB106B
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[289]
HepG2 DEFB106B
Missing
[290]
HepG2.C3A DEFB106B
Missing
[291]
HuH.7 DEFB106B
Missing
[292]
SNU475 DEFB106B
Missing
[293]
THLE DEFB106B
Missing
[294]
liver DEFB106B
Missing