REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CERS2 Ceramide synthase 2 [1] -0.92[2] -1.37[3] -0.42[4] -1.04[5] -1.35[6] -0.68[7]
2 ORMDL3 ORM1-like protein 3 [8] -1.06[9] -0.99[10] -1.63[11] -2.99[12] -2.06[13] -1.44[14]
3 ALDH3A2 Fatty aldehyde dehydrogenase [15] -0.15[16] -0.37[17] -0.93[18] -0.90[19] -1.47[20] 0.15[21]
4 CERS4 Ceramide synthase 4 [22] -0.98[23] -0.28[24] -0.59[25] -3.57[26] -3.32[27] -0.50[28]
5 DEGS1 Sphingolipid delta(4)-desaturase DES1 [29] -0.82[30] -1.47[31] -1.37[32] 1.07[33] 0.76[34] -0.74[35]
6 ORMDL2 ORM1-like protein 2 [36] -1.17[37] -1.78[38] -2.11[39] -1.42[40] -1.25[41] -1.18[42]
7 SPTSSA Serine palmitoyltransferase small subunit A [43] 0.92[44] 0.96[45] 0.47[46] -0.38[47] -0.25[48] -0.89[49]
8 SPTLC1 Serine palmitoyltransferase 1 [50] 0.03[51] 0.57[52] -0.13[53] 0.15[54] 1.08[55] -1.10[56]
9 OSBP Oxysterol-binding protein 1 [57] 0.05[58] 0.11[59] 1.62[60] 0.28[61] 0.42[62] 1.56[63]
10 SPHK1 Sphingosine kinase 1 [64] 1.43[65] 2.00[66] -0.51[67] -2.39[68] 0.16[69] -5.27[70]
11 VAPA Vesicle-associated membrane protein-associated protein A [71] 1.73[72] 1.58[73] 1.86[74] 2.26[75] 1.77[76] 1.34[77]
12 SGPP1 Sphingosine-1-phosphate phosphatase 1 [78] -1.03[79] -1.02[80] -2.11[81] -0.69[82] -0.20[83] 0.44[84]
13 KDSR 3-ketodihydrosphingosine reductase [85] -0.71[86] -0.52[87] -1.12[88] -0.40[89] 0.83[90] 1.28[91]
14 CSNK1G2 Casein kinase I isoform gamma-2 [92] 1.25[93] 1.07[94] 0.98[95] -0.18[96] 0.81[97] -1.11[98]
15 VAPB Vesicle-associated membrane protein-associated protein B/C [99] 1.58[100] 1.57[101] 1.07[102] 1.93[103] 1.51[104] 1.08[105]
16 ORMDL1 ORM1-like protein 1 [106] -0.38[107] 1.23[108] 0.44[109] 0.25[110] 0.93[111] 0.63[112]
17 CERS5 Ceramide synthase 5 [113] 0.44[114] -0.27[115] -0.68[116] 0.11[117] 0.38[118] -1.34[119]
18 SPTLC3 Serine palmitoyltransferase 3 [120] -0.61[121] 0.37[122] 1.76[123] -3.69[124] -1.20[125] 0.49[126]
19 SGPL1 Sphingosine-1-phosphate lyase 1 [127] 1.89[128] 1.20[129] 0.42[130] 1.42[131] 1.14[132] 1.99[133]
20 SGMS1 Phosphatidylcholine:ceramide cholinephosphotransferase 1 [134] -0.71[135] 0.15[136] -0.90[137] 0.85[138] 1.07[139] 0.82[140]
21 CERS6 Ceramide synthase 6 [141] 0.39[142] 0.21[143] 2.07[144] 1.02[145] 0.79[146] 1.10[147]
22 SPHK2 Sphingosine kinase 2 [148] -0.30[149] -0.24[150] -0.55[151] -0.02[152] -0.32[153] 0.14[154]
23 PRKD2 Serine/threonine-protein kinase D2 [155] 0.75[156] 0.14[157] 1.20[158] 1.01[159] 1.19[160] -0.37[161]
24 SGMS2 Phosphatidylcholine:ceramide cholinephosphotransferase 2 [162] -2.18[163] -1.94[164] -6.02[165] 0.72[166] 2.25[167] 1.55[168]
25 SAMD8 Sphingomyelin synthase-related protein 1 [169] 0.94[170] 1.79[171] 0.83[172] 2.18[173] 2.34[174] 1.59[175]
26 PRKD3 Serine/threonine-protein kinase D3 [176] 1.65[177] 2.05[178] 1.88[179] 2.99[180] 2.96[181] 1.97[182]
27 SPTLC2 Serine palmitoyltransferase 2 [183] 2.46[184] 2.16[185] 1.24[186] 2.58[187] 2.53[188] 2.57[189]
28 SPNS2 Protein spinster homolog 2 [190] -1.92[191] -3.97[192] -6.09[193] -3.68[194] -3.93[195] 0.48[196]
29 ACER3 Alkaline ceramidase 3 [197] 0.93[198] 0.19[199] 0.04[200] 1.99[201] 2.20[202] 1.31[203]
30 ALDH3B1 Aldehyde dehydrogenase family 3 member B1 [204] 1.73[205] 1.68[206] 1.22[207] 4.57[208] 2.97[209] -0.35[210]
31 CERS1 Ceramide synthase 1 [211] 1.23[212] 0.07[213] 1.76[214] -1.53[215] -1.35[216] [217]
32 PPM1L Protein phosphatase 1L [218] -0.45[219] 0.16[220] 3.26[221] -2.26[222] -0.97[223] 2.98[224]
33 ACER2 Alkaline ceramidase 2 [225] 2.65[226] 1.58[227] 0.47[228] -0.84[229] 2.01[230] 2.70[231]
34 PRKD1 Serine/threonine-protein kinase D1 [232] 1.78[233] 1.55[234] 3.91[235] 4.45[236] 4.71[237] 2.87[238]
35 FA2H Fatty acid 2-hydroxylase [239] 0.73[240] 0.27[241] -2.02[242] -1.27[243] -1.81[244] 0.14[245]
36 SPTSSB Serine palmitoyltransferase small subunit B [246] 2.30[247] 1.00[248] 7.97[249] -2.84[250] -2.47[251] 0.64[252]
37 DEGS2 Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 [253] 4.64[254] -1.43[255] 0.44[256] 0.96[257] -1.24[258] 2.75[259]
38 ALDH3B2 Aldehyde dehydrogenase family 3 member B2 [260] [261] [262] [263] [264] [265] [266]
39 ACER1 Alkaline ceramidase 1 [267] [268] [269] [270] [271] [272] [273]
40 CERS3 Ceramide synthase 3 [274] [275] [276] [277] [278] [279] [280]
41 CERT1 [281] [282] [283] [284] [285] [286] [287]
42 SGPP2 Sphingosine-1-phosphate phosphatase 2 [288] [289] [290] [291] [292] [293] [294]
43 PLPP2 Phospholipid phosphatase 2 [295] [296] [297] [298] [299] [300] [301]
44 PLPP3 Phospholipid phosphatase 3 [302] [303] [304] [305] [306] [307] [308]
45 PLPP1 Phospholipid phosphatase 1 [309] [310] [311] [312] [313] [314] [315]
[1]
ref_hepatocyte CERS2
Mean 112
Standard deviation 71
Values 70 60 53 2e+02 1.8e+02
[2]
HepG2 CERS2
Mean 145
Standard deviation 9.9
Values 1.4e+02 1.5e+02
[3]
HepG2.C3A CERS2
Mean 103
Standard deviation 32
Values 1.3e+02 81
[4]
HuH.7 CERS2
Mean 194
Standard deviation 72
Values 1.5e+02 2.8e+02 1.6e+02
[5]
SNU475 CERS2
Mean 114
Standard deviation 11
Values 1.2e+02 1.1e+02
[6]
THLE CERS2
Mean 84.7
Standard deviation 14
Values 74 95
[7]
liver CERS2
Mean 121
Standard deviation 29
Values 1.6e+02 86 1.3e+02 1.1e+02
[8]
ref_hepatocyte ORMDL3
Mean 50.4
Standard deviation 19
Values 21 46 55 58 72
[9]
HepG2 ORMDL3
Mean 58.9
Standard deviation 7.2
Values 54 64
[10]
HepG2.C3A ORMDL3
Mean 60.2
Standard deviation 17
Values 72 48
[11]
HuH.7 ORMDL3
Mean 37.6
Standard deviation 4.3
Values 35 35 43
[12]
SNU475 ORMDL3
Mean 13.3
Standard deviation 2.5
Values 15 12
[13]
THLE ORMDL3
Mean 23.2
Standard deviation 1.3
Values 22 24
[14]
liver ORMDL3
Mean 31.8
Standard deviation 21
Values 19 47 9.3 52
[15]
ref_hepatocyte ALDH3A2
Mean 44.1
Standard deviation 25
Values 41 52 7.1 44 76
[16]
HepG2 ALDH3A2
Mean 97
Standard deviation 12
Values 89 1.1e+02
[17]
HepG2.C3A ALDH3A2
Mean 80.8
Standard deviation 15
Values 70 91
[18]
HuH.7 ALDH3A2
Mean 53.4
Standard deviation 2.9
Values 55 55 50
[19]
SNU475 ALDH3A2
Mean 49.4
Standard deviation 7.9
Values 55 44
[20]
THLE ALDH3A2
Mean 30.6
Standard deviation 2.4
Values 29 32
[21]
liver ALDH3A2
Mean 83.6
Standard deviation 21
Values 85 88 1.1e+02 55
[22]
ref_hepatocyte CERS4
Mean 16.6
Standard deviation 15
Values 9 2.4 6.6 32 33
[23]
HepG2 CERS4
Mean 20.5
Standard deviation 3
Values 18 23
[24]
HepG2.C3A CERS4
Mean 32.3
Standard deviation 9.4
Values 39 26
[25]
HuH.7 CERS4
Mean 25.4
Standard deviation 2.5
Values 23 28 26
[26]
SNU475 CERS4
Mean 2.93
Standard deviation 0.81
Values 3.5 2.4
[27]
THLE CERS4
Mean 3.19
Standard deviation 0.32
Values 3.4 3
[28]
liver CERS4
Mean 20
Standard deviation 11
Values 34 9.6 22 14
[29]
ref_hepatocyte DEGS1
Mean 15.3
Standard deviation 7.6
Values 11 29 14 11 13
[30]
HepG2 DEGS1
Mean 21.1
Standard deviation 0.78
Values 21 22
[31]
HepG2.C3A DEGS1
Mean 13.1
Standard deviation 0.69
Values 13 14
[32]
HuH.7 DEGS1
Mean 13.6
Standard deviation 0.88
Values 13 13 15
[33]
SNU475 DEGS1
Mean 67.4
Standard deviation 6.7
Values 72 63
[34]
THLE DEGS1
Mean 50.1
Standard deviation 5.8
Values 46 54
[35]
liver DEGS1
Mean 15.7
Standard deviation 8.4
Values 21 10 24 7.2
[36]
ref_hepatocyte ORMDL2
Mean 14.2
Standard deviation 6.6
Values 5.2 15 15 23 12
[37]
HepG2 ORMDL2
Mean 15.4
Standard deviation 1.8
Values 14 17
[38]
HepG2.C3A ORMDL2
Mean 9.81
Standard deviation 0.96
Values 9.1 10
[39]
HuH.7 ORMDL2
Mean 7.62
Standard deviation 2.2
Values 8.1 5.3 9.5
[40]
SNU475 ORMDL2
Mean 11.1
Standard deviation 1.4
Values 10 12
[41]
THLE ORMDL2
Mean 11.5
Standard deviation 1.7
Values 10 13
[42]
liver ORMDL2
Mean 10.7
Standard deviation 7.1
Values 17 4.7 17 4.5
[43]
ref_hepatocyte SPTSSA
Mean 14.1
Standard deviation 11
Values 32 5.8 13 5.9 14
[44]
HepG2 SPTSSA
Mean 65.2
Standard deviation 6.4
Values 61 70
[45]
HepG2.C3A SPTSSA
Mean 65.3
Standard deviation 5.6
Values 69 61
[46]
HuH.7 SPTSSA
Mean 45
Standard deviation 5.4
Values 42 42 51
[47]
SNU475 SPTSSA
Mean 22.8
Standard deviation 4.6
Values 26 20
[48]
THLE SPTSSA
Mean 22.9
Standard deviation 0.71
Values 22 23
[49]
liver SPTSSA
Mean 13.1
Standard deviation 7.9
Values 18 8.1 22 4.9
[50]
ref_hepatocyte SPTLC1
Mean 13.7
Standard deviation 9.5
Values 29 16 10 5.2 7.7
[51]
HepG2 SPTLC1
Mean 33.9
Standard deviation 2.4
Values 32 36
[52]
HepG2.C3A SPTLC1
Mean 48.2
Standard deviation 6.8
Values 43 53
[53]
HuH.7 SPTLC1
Mean 28.8
Standard deviation 0.78
Values 28 30 28
[54]
SNU475 SPTLC1
Mean 31.8
Standard deviation 5.1
Values 35 28
[55]
THLE SPTLC1
Mean 55.7
Standard deviation 4
Values 53 59
[56]
liver SPTLC1
Mean 10.9
Standard deviation 1.2
Values 12 10 12 9.6
[57]
ref_hepatocyte OSBP
Mean 12.2
Standard deviation 4.2
Values 8.9 8.9 10 19 14
[58]
HepG2 OSBP
Mean 30.7
Standard deviation 3.1
Values 29 33
[59]
HepG2.C3A OSBP
Mean 31.2
Standard deviation 8.1
Values 37 25
[60]
HuH.7 OSBP
Mean 86.5
Standard deviation 8
Values 88 93 78
[61]
SNU475 OSBP
Mean 31
Standard deviation 1
Values 32 30
[62]
THLE OSBP
Mean 31.5
Standard deviation 3.5
Values 29 34
[63]
liver OSBP
Mean 61.7
Standard deviation 29
Values 38 88 36 85
[64]
ref_hepatocyte SPHK1
Mean 11.5
Standard deviation 14
Values 32 4.8 19 1.4 0.27
[65]
HepG2 SPHK1
Mean 75.9
Standard deviation 8.5
Values 82 70
[66]
HepG2.C3A SPHK1
Mean 109
Standard deviation 8.6
Values 1.2e+02 1e+02
[67]
HuH.7 SPHK1
Mean 18.7
Standard deviation 5.5
Values 19 13 24
[68]
SNU475 SPHK1
Mean 4.6
Standard deviation 3.4
Values 2.2 7
[69]
THLE SPHK1
Mean 24.9
Standard deviation 0.21
Values 25 25
[70]
liver SPHK1
Mean 0.512
Standard deviation 0.41
Values 1.1 0.3 0.18 0.46
[71]
ref_hepatocyte VAPA
Mean 11.3
Standard deviation 4.4
Values 18 12 6.3 9 11
[72]
HepG2 VAPA
Mean 91.1
Standard deviation 18
Values 78 1e+02
[73]
HepG2.C3A VAPA
Mean 79.8
Standard deviation 8.1
Values 74 86
[74]
HuH.7 VAPA
Mean 94.5
Standard deviation 11
Values 82 97 1e+02
[75]
SNU475 VAPA
Mean 113
Standard deviation 9.3
Values 1.2e+02 1.1e+02
[76]
THLE VAPA
Mean 73.9
Standard deviation 5.5
Values 70 78
[77]
liver VAPA
Mean 49
Standard deviation 18
Values 61 36 68 31
[78]
ref_hepatocyte SGPP1
Mean 7.99
Standard deviation 3
Values 7.2 12 5.3 5.3 9.9
[79]
HepG2 SGPP1
Mean 9.55
Standard deviation 2.3
Values 11 7.9
[80]
HepG2.C3A SGPP1
Mean 9.38
Standard deviation 2.5
Values 11 7.6
[81]
HuH.7 SGPP1
Mean 4.25
Standard deviation 1.5
Values 3.2 6 3.5
[82]
SNU475 SGPP1
Mean 10.4
Standard deviation 1.7
Values 12 9.2
[83]
THLE SGPP1
Mean 13.4
Standard deviation 2.4
Values 12 15
[84]
liver SGPP1
Mean 18.6
Standard deviation 3.6
Values 19 18 14 23
[85]
ref_hepatocyte KDSR
Mean 7.84
Standard deviation 4.1
Values 2.7 6.3 6.7 14 10
[86]
HepG2 KDSR
Mean 11.7
Standard deviation 1.3
Values 13 11
[87]
HepG2.C3A KDSR
Mean 13
Standard deviation 4.2
Values 16 10
[88]
HuH.7 KDSR
Mean 8.32
Standard deviation 1.2
Values 9.1 8.9 7
[89]
SNU475 KDSR
Mean 12.4
Standard deviation 1.4
Values 13 11
[90]
THLE KDSR
Mean 26.9
Standard deviation 5
Values 23 30
[91]
liver KDSR
Mean 32.7
Standard deviation 10
Values 38 33 42 19
[92]
ref_hepatocyte CSNK1G2
Mean 7.57
Standard deviation 4.9
Values 3.2 6.6 16 7.6 4.7
[93]
HepG2 CSNK1G2
Mean 43.8
Standard deviation 9.5
Values 51 37
[94]
HepG2.C3A CSNK1G2
Mean 37.9
Standard deviation 5.4
Values 42 34
[95]
HuH.7 CSNK1G2
Mean 34.4
Standard deviation 3.9
Values 36 30 37
[96]
SNU475 CSNK1G2
Mean 14
Standard deviation 1.1
Values 15 13
[97]
THLE CSNK1G2
Mean 25.6
Standard deviation 1.1
Values 25 26
[98]
liver CSNK1G2
Mean 6.02
Standard deviation 2.9
Values 3.9 7.8 3.2 9.1
[99]
ref_hepatocyte VAPB
Mean 6.56
Standard deviation 4.1
Values 12 9.3 5 2.9 3.3
[100]
HepG2 VAPB
Mean 47.7
Standard deviation 1.3
Values 49 47
[101]
HepG2.C3A VAPB
Mean 46.4
Standard deviation 0.32
Values 46 47
[102]
HuH.7 VAPB
Mean 31.8
Standard deviation 0.96
Values 33 31 32
[103]
SNU475 VAPB
Mean 52.3
Standard deviation 4.7
Values 56 49
[104]
THLE VAPB
Mean 36
Standard deviation 4.3
Values 33 39
[105]
liver VAPB
Mean 23.8
Standard deviation 0.99
Values 23 24 25 23
[106]
ref_hepatocyte ORMDL1
Mean 6.3
Standard deviation 2.4
Values 3.8 4.8 5.8 9.9 7.2
[107]
HepG2 ORMDL1
Mean 11.8
Standard deviation 4.6
Values 8.5 15
[108]
HepG2.C3A ORMDL1
Mean 35.2
Standard deviation 4.1
Values 38 32
[109]
HuH.7 ORMDL1
Mean 19.7
Standard deviation 2.6
Values 19 18 23
[110]
SNU475 ORMDL1
Mean 15.7
Standard deviation 0.21
Values 16 16
[111]
THLE ORMDL1
Mean 23
Standard deviation 2.2
Values 25 22
[112]
liver ORMDL1
Mean 16.7
Standard deviation 10
Values 26 8.2 25 7.3
[113]
ref_hepatocyte CERS5
Mean 5.89
Standard deviation 2.7
Values 9.3 8.2 4.7 4.1 3.2
[114]
HepG2 CERS5
Mean 19.4
Standard deviation 4.7
Values 23 16
[115]
HepG2.C3A CERS5
Mean 11.6
Standard deviation 2.1
Values 13 10
[116]
HuH.7 CERS5
Mean 8.47
Standard deviation 1.1
Values 8.8 7.2 9.4
[117]
SNU475 CERS5
Mean 13.3
Standard deviation 1.2
Values 14 12
[118]
THLE CERS5
Mean 14.7
Standard deviation 0.49
Values 14 15
[119]
liver CERS5
Mean 4
Standard deviation 1.8
Values 4.3 2.9 6.4 2.3
[120]
ref_hepatocyte SPTLC3
Mean 5.24
Standard deviation 6.1
Values 16 2.4 0.46 3.8 3.6
[121]
HepG2 SPTLC3
Mean 8.34
Standard deviation 6.7
Values 3.6 13
[122]
HepG2.C3A SPTLC3
Mean 16.1
Standard deviation 0.65
Values 16 17
[123]
HuH.7 SPTLC3
Mean 40.8
Standard deviation 8.5
Values 44 47 31
[124]
SNU475 SPTLC3
Mean 0.852
Standard deviation 0.78
Values 1.4 0.3
[125]
THLE SPTLC3
Mean 4.39
Standard deviation 0.48
Values 4.1 4.7
[126]
liver SPTLC3
Mean 12.6
Standard deviation 6
Values 13 9.1 7.4 21
[127]
ref_hepatocyte SGPL1
Mean 5.24
Standard deviation 1.1
Values 5.1 6 3.5 5.2 6.5
[128]
HepG2 SGPL1
Mean 47.3
Standard deviation 3.3
Values 45 50
[129]
HepG2.C3A SGPL1
Mean 28.5
Standard deviation 0.64
Values 28 29
[130]
HuH.7 SGPL1
Mean 16.1
Standard deviation 4.5
Values 20 11 16
[131]
SNU475 SGPL1
Mean 29.4
Standard deviation 7.1
Values 34 24
[132]
THLE SGPL1
Mean 22.3
Standard deviation 1.4
Values 21 23
[133]
liver SGPL1
Mean 35.6
Standard deviation 3
Values 32 38 34 38
[134]
ref_hepatocyte SGMS1
Mean 4.43
Standard deviation 2
Values 4.2 7.7 4.1 2.2 3.9
[135]
HepG2 SGMS1
Mean 6.6
Standard deviation 2.6
Values 4.8 8.4
[136]
HepG2.C3A SGMS1
Mean 11.6
Standard deviation 2.4
Values 13 10
[137]
HuH.7 SGMS1
Mean 5.45
Standard deviation 1.4
Values 4.7 7.1 4.6
[138]
SNU475 SGMS1
Mean 16.7
Standard deviation 3.8
Values 19 14
[139]
THLE SGMS1
Mean 17.9
Standard deviation 2
Values 16 19
[140]
liver SGMS1
Mean 13.4
Standard deviation 1.8
Values 15 14 11 13
[141]
ref_hepatocyte CERS6
Mean 4.39
Standard deviation 3.9
Values 11 2.8 2.5 3 2.2
[142]
HepG2 CERS6
Mean 14
Standard deviation 4
Values 11 17
[143]
HepG2.C3A CERS6
Mean 12.1
Standard deviation 1.2
Values 11 13
[144]
HuH.7 CERS6
Mean 42.6
Standard deviation 12
Values 48 51 29
[145]
SNU475 CERS6
Mean 18.7
Standard deviation 5.2
Values 22 15
[146]
THLE CERS6
Mean 14.7
Standard deviation 0.18
Values 15 15
[147]
liver CERS6
Mean 16.1
Standard deviation 6.9
Values 8.3 23 12 21
[148]
ref_hepatocyte SPHK2
Mean 3.26
Standard deviation 2
Values 1.5 2.2 2.2 4 6.4
[149]
HepG2 SPHK2
Mean 6.43
Standard deviation 0.066
Values 6.4 6.5
[150]
HepG2.C3A SPHK2
Mean 6.53
Standard deviation 0.22
Values 6.4 6.7
[151]
HuH.7 SPHK2
Mean 5.14
Standard deviation 0.89
Values 5.8 4.1 5.5
[152]
SNU475 SPHK2
Mean 6.71
Standard deviation 0.21
Values 6.9 6.6
[153]
THLE SPHK2
Mean 5.03
Standard deviation 1.4
Values 4 6
[154]
liver SPHK2
Mean 6.15
Standard deviation 2.7
Values 8.7 3 8 4.9
[155]
ref_hepatocyte PRKD2
Mean 3.08
Standard deviation 2.1
Values 1.1 1.8 6.5 2.9 3.2
[156]
HepG2 PRKD2
Mean 12.6
Standard deviation 2.6
Values 14 11
[157]
HepG2.C3A PRKD2
Mean 8.05
Standard deviation 2.1
Values 9.5 6.6
[158]
HuH.7 PRKD2
Mean 16.3
Standard deviation 2.6
Values 19 15 15
[159]
SNU475 PRKD2
Mean 13
Standard deviation 0.097
Values 13 13
[160]
THLE PRKD2
Mean 13.5
Standard deviation 0.74
Values 13 14
[161]
liver PRKD2
Mean 4.08
Standard deviation 1.3
Values 5.2 2.5 3.6 5
[162]
ref_hepatocyte SGMS2
Mean 2.9
Standard deviation 2.1
Values 0.63 5.5 4.8 1.9 1.7
[163]
HepG2 SGMS2
Mean 1.56
Standard deviation 0.49
Values 1.2 1.9
[164]
HepG2.C3A SGMS2
Mean 1.79
Standard deviation 0.25
Values 1.6 2
[165]
HuH.7 SGMS2
Mean 0.103
Standard deviation 0.058
Values 0.12 0.15 0.037
[166]
SNU475 SGMS2
Mean 9.95
Standard deviation 0.77
Values 10 9.4
[167]
THLE SGMS2
Mean 26.6
Standard deviation 0.49
Values 26 27
[168]
liver SGMS2
Mean 14.5
Standard deviation 4.2
Values 11 20 12 16
[169]
ref_hepatocyte SAMD8
Mean 2.25
Standard deviation 1.2
Values 2.4 3.8 2.8 1.3 1
[170]
HepG2 SAMD8
Mean 10.5
Standard deviation 1.4
Values 9.5 11
[171]
HepG2.C3A SAMD8
Mean 18.5
Standard deviation 1.7
Values 20 17
[172]
HuH.7 SAMD8
Mean 9.22
Standard deviation 2.6
Values 8.6 12 7
[173]
SNU475 SAMD8
Mean 21.3
Standard deviation 5.7
Values 25 17
[174]
THLE SAMD8
Mean 22
Standard deviation 0.023
Values 22 22
[175]
liver SAMD8
Mean 11.6
Standard deviation 3.5
Values 8.8 16 9.1 12
[176]
ref_hepatocyte PRKD3
Mean 1.89
Standard deviation 0.39
Values 2.2 2.2 2.1 1.4 1.6
[177]
HepG2 PRKD3
Mean 14.5
Standard deviation 5.5
Values 11 18
[178]
HepG2.C3A PRKD3
Mean 18.6
Standard deviation 3.7
Values 16 21
[179]
HuH.7 PRKD3
Mean 16
Standard deviation 2.7
Values 19 14 15
[180]
SNU475 PRKD3
Mean 31.6
Standard deviation 0.07
Values 32 32
[181]
THLE PRKD3
Mean 28.4
Standard deviation 3.4
Values 31 26
[182]
liver PRKD3
Mean 12.7
Standard deviation 6.3
Values 8.9 19 5.9 17
[183]
ref_hepatocyte SPTLC2
Mean 1.58
Standard deviation 0.68
Values 2.6 2 1.4 1 0.98
[184]
HepG2 SPTLC2
Mean 21.1
Standard deviation 1.1
Values 20 22
[185]
HepG2.C3A SPTLC2
Mean 16.8
Standard deviation 1.3
Values 18 16
[186]
HuH.7 SPTLC2
Mean 8.59
Standard deviation 1.7
Values 8.9 10 6.7
[187]
SNU475 SPTLC2
Mean 19.7
Standard deviation 6.3
Values 24 15
[188]
THLE SPTLC2
Mean 17.6
Standard deviation 5.3
Values 14 21
[189]
liver SPTLC2
Mean 16
Standard deviation 6.3
Values 8.8 24 14 18
[190]
ref_hepatocyte SPNS2
Mean 1.39
Standard deviation 1.2
Values 0 2.9 2.2 1.2 0.58
[191]
HepG2 SPNS2
Mean 0.891
Standard deviation 0.51
Values 1.3 0.53
[192]
HepG2.C3A SPNS2
Mean 0.209
Standard deviation 0.0073
Values 0.2 0.21
[193]
HuH.7 SPNS2
Mean 0.047
Standard deviation 0.033
Values 0.025 0.032 0.084
[194]
SNU475 SPNS2
Mean 0.227
Standard deviation 0.14
Values 0.13 0.32
[195]
THLE SPNS2
Mean 0.176
Standard deviation 0.053
Values 0.21 0.14
[196]
liver SPNS2
Mean 3.32
Standard deviation 1.7
Values 3.1 2.9 1.6 5.7
[197]
ref_hepatocyte ACER3
Mean 1.37
Standard deviation 1.3
Values 3.4 2 0.49 0.57 0.37
[198]
HepG2 ACER3
Mean 6.31
Standard deviation 1.9
Values 5 7.7
[199]
HepG2.C3A ACER3
Mean 3.71
Standard deviation 1.6
Values 2.6 4.8
[200]
HuH.7 ACER3
Mean 3.23
Standard deviation 0.99
Values 3.9 3.7 2.1
[201]
SNU475 ACER3
Mean 11.3
Standard deviation 0.77
Values 12 11
[202]
THLE ACER3
Mean 12
Standard deviation 1.3
Values 11 13
[203]
liver ACER3
Mean 5.81
Standard deviation 1.3
Values 7.4 6.1 4.1 5.7
[204]
ref_hepatocyte ALDH3B1
Mean 1.3
Standard deviation 0.3
Values 1.8 1.2 1.2 1.1 1.2
[205]
HepG2 ALDH3B1
Mean 10.5
Standard deviation 1.5
Values 12 9.5
[206]
HepG2.C3A ALDH3B1
Mean 9.94
Standard deviation 4.7
Values 13 6.6
[207]
HuH.7 ALDH3B1
Mean 6.99
Standard deviation 0.87
Values 8 6.4 6.6
[208]
SNU475 ALDH3B1
Mean 64.9
Standard deviation 36
Values 91 39
[209]
THLE ALDH3B1
Mean 19.7
Standard deviation 1.7
Values 18 21
[210]
liver ALDH3B1
Mean 1.75
Standard deviation 0.18
Values 2 1.6 1.8 1.7
[211]
ref_hepatocyte CERS1
Mean 0.438
Standard deviation 0.8
Values 1.8 0 0.27 0.069 0
[212]
HepG2 CERS1
Mean 2.5
Standard deviation 0.7
Values 3 2
[213]
HepG2.C3A CERS1
Mean 1.09
Standard deviation 0.42
Values 1.4 0.79
[214]
HuH.7 CERS1
Mean 3.42
Standard deviation 0.65
Values 2.7 3.5 4
[215]
SNU475 CERS1
Mean 0.316
Standard deviation 0.04
Values 0.29 0.34
[216]
THLE CERS1
Mean 0.329
Standard deviation 0.045
Values 0.36 0.3
[217]
liver CERS1
Mean 0
Standard deviation 0
Values 0 0 0 0
[218]
ref_hepatocyte PPM1L
Mean 0.27
Standard deviation 0.21
Values 0 0.38 0.29 0.55 0.13
[219]
HepG2 PPM1L
Mean 0.482
Standard deviation 0.3
Values 0.27 0.69
[220]
HepG2.C3A PPM1L
Mean 0.717
Standard deviation 0.38
Values 0.45 0.99
[221]
HuH.7 PPM1L
Mean 5.97
Standard deviation 3.6
Values 6.9 9.1 2
[222]
SNU475 PPM1L
Mean 0.118
Standard deviation 0.023
Values 0.13 0.1
[223]
THLE PPM1L
Mean 0.266
Standard deviation 0.14
Values 0.17 0.37
[224]
liver PPM1L
Mean 3.65
Standard deviation 2.5
Values 1.5 6.5 1.6 5
[225]
ref_hepatocyte ACER2
Mean 0.176
Standard deviation 0.16
Values 0.33 0.37 0 0.095 0.089
[226]
HepG2 ACER2
Mean 2.68
Standard deviation 0.26
Values 2.5 2.9
[227]
HepG2.C3A ACER2
Mean 1.25
Standard deviation 0.68
Values 0.77 1.7
[228]
HuH.7 ACER2
Mean 0.563
Standard deviation 0.29
Values 0.87 0.54 0.28
[229]
SNU475 ACER2
Mean 0.206
Standard deviation 0.011
Values 0.21 0.2
[230]
THLE ACER2
Mean 1.37
Standard deviation 0.099
Values 1.3 1.4
[231]
liver ACER2
Mean 1.96
Standard deviation 1.3
Values 0.59 3.7 1.3 2.2
[232]
ref_hepatocyte PRKD1
Mean 0.138
Standard deviation 0.15
Values 0 0.35 0.068 0.23 0.041
[233]
HepG2 PRKD1
Mean 1.15
Standard deviation 0.62
Values 1.6 0.72
[234]
HepG2.C3A PRKD1
Mean 0.962
Standard deviation 0.54
Values 0.58 1.3
[235]
HuH.7 PRKD1
Mean 4.8
Standard deviation 2.2
Values 4.2 7.3 3
[236]
SNU475 PRKD1
Mean 6.34
Standard deviation 1.5
Values 7.4 5.3
[237]
THLE PRKD1
Mean 6.96
Standard deviation 0.4
Values 7.2 6.7
[238]
liver PRKD1
Mean 1.73
Standard deviation 0.37
Values 1.4 1.9 1.5 2.1
[239]
ref_hepatocyte FA2H
Mean 0.036
Standard deviation 0.049
Values 0 0.096 0.084 0 0
[240]
HepG2 FA2H
Mean 0.145
Standard deviation 0.078
Values 0.2 0.09
[241]
HepG2.C3A FA2H
Mean 0.103
Standard deviation 0.036
Values 0.078 0.13
[242]
HuH.7 FA2H
Mean 0.0205
Standard deviation 0.023
Values 0.0082 0.0064 0.047
[243]
SNU475 FA2H
Mean 0.0312
Standard deviation 0.0083
Values 0.037 0.025
[244]
THLE FA2H
Mean 0.0198
Standard deviation 0.0054
Values 0.024 0.016
[245]
liver FA2H
Mean 0.068
Standard deviation 0.068
Values 0.024 0 0.1 0.15
[246]
ref_hepatocyte SPTSSB
Mean 0.0332
Standard deviation 0.047
Values 0 0.1 0 0 0.065
[247]
HepG2 SPTSSB
Mean 0.399
Standard deviation 0.078
Values 0.34 0.45
[248]
HepG2.C3A SPTSSB
Mean 0.158
Standard deviation 0.14
Values 0.058 0.26
[249]
HuH.7 SPTSSB
Mean 19.2
Standard deviation 3.3
Values 19 16 23
[250]
SNU475 SPTSSB
Mean 0.00971
Standard deviation 0.00061
Values 0.0093 0.01
[251]
THLE SPTSSB
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[252]
liver SPTSSB
Mean 0.0886
Standard deviation 0.019
Values 0.071 0.11 0.077 0.093
[253]
ref_hepatocyte DEGS2
Mean 0.0171
Standard deviation 0.038
Values 0 0.085 0 0 0
[254]
HepG2 DEGS2
Mean 1.04
Standard deviation 1
Values 1.8 0.3
[255]
HepG2.C3A DEGS2
Mean 0.0151
Standard deviation 0.0062
Values 0.019 0.011
[256]
HuH.7 DEGS2
Mean 0.0534
Standard deviation 0.032
Values 0.033 0.09 0.037
[257]
SNU475 DEGS2
Mean 0.0696
Standard deviation 0.02
Values 0.083 0.056
[258]
THLE DEGS2
Mean 0.0139
Standard deviation 0.0029
Values 0.012 0.016
[259]
liver DEGS2
Mean 0.197
Standard deviation 0.15
Values 0.094 0.14 0.13 0.42
[260]
ref_hepatocyte ALDH3B2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[261]
HepG2 ALDH3B2
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[262]
HepG2.C3A ALDH3B2
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[263]
HuH.7 ALDH3B2
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[264]
SNU475 ALDH3B2
Mean 0.0312
Standard deviation 0.0083
Values 0.037 0.025
[265]
THLE ALDH3B2
Mean 0.0112
Standard deviation 0.00084
Values 0.012 0.011
[266]
liver ALDH3B2
Mean 0.00331
Standard deviation 0.0066
Values 0 0 0 0.013
[267]
ref_hepatocyte ACER1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[268]
HepG2 ACER1
Mean 0
Standard deviation 0
Values 0 0
[269]
HepG2.C3A ACER1
Mean 0
Standard deviation 0
Values 0 0
[270]
HuH.7 ACER1
Mean 0
Standard deviation 0
Values 0 0 0
[271]
SNU475 ACER1
Mean 0
Standard deviation 0
Values 0 0
[272]
THLE ACER1
Mean 0
Standard deviation 0
Values 0 0
[273]
liver ACER1
Mean 0.0162
Standard deviation 0.024
Values 0 0 0.051 0.013
[274]
ref_hepatocyte CERS3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[275]
HepG2 CERS3
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[276]
HepG2.C3A CERS3
Mean 0
Standard deviation 0
Values 0 0
[277]
HuH.7 CERS3
Mean 0.0509
Standard deviation 0.029
Values 0.041 0.083 0.028
[278]
SNU475 CERS3
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[279]
THLE CERS3
Mean 0.0263
Standard deviation 0.03
Values 0.047 0.0053
[280]
liver CERS3
Mean 0.0104
Standard deviation 0.014
Values 0 0.029 0 0.013
[281]
ref_hepatocyte CERT1
Missing
[282]
HepG2 CERT1
Missing
[283]
HepG2.C3A CERT1
Missing
[284]
HuH.7 CERT1
Missing
[285]
SNU475 CERT1
Missing
[286]
THLE CERT1
Missing
[287]
liver CERT1
Missing
[288]
ref_hepatocyte SGPP2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[289]
HepG2 SGPP2
Mean 0.0222
Standard deviation 0.001
Values 0.023 0.021
[290]
HepG2.C3A SGPP2
Mean 0.0458
Standard deviation 0.004
Values 0.049 0.043
[291]
HuH.7 SGPP2
Mean 0.0568
Standard deviation 0.037
Values 0.057 0.019 0.094
[292]
SNU475 SGPP2
Mean 0.83
Standard deviation 0.33
Values 1.1 0.59
[293]
THLE SGPP2
Mean 0.218
Standard deviation 0.075
Values 0.17 0.27
[294]
liver SGPP2
Mean 0.0995
Standard deviation 0.11
Values 0.26 0.1 0 0.04
[295]
ref_hepatocyte PLPP2
Missing
[296]
HepG2 PLPP2
Missing
[297]
HepG2.C3A PLPP2
Missing
[298]
HuH.7 PLPP2
Missing
[299]
SNU475 PLPP2
Missing
[300]
THLE PLPP2
Missing
[301]
liver PLPP2
Missing
[302]
ref_hepatocyte PLPP3
Missing
[303]
HepG2 PLPP3
Missing
[304]
HepG2.C3A PLPP3
Missing
[305]
HuH.7 PLPP3
Missing
[306]
SNU475 PLPP3
Missing
[307]
THLE PLPP3
Missing
[308]
liver PLPP3
Missing
[309]
ref_hepatocyte PLPP1
Missing
[310]
HepG2 PLPP1
Missing
[311]
HepG2.C3A PLPP1
Missing
[312]
HuH.7 PLPP1
Missing
[313]
SNU475 PLPP1
Missing
[314]
THLE PLPP1
Missing
[315]
liver PLPP1
Missing