REACTOME_SIGNAL_AMPLIFICATION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | GNG5 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | -1.14[1] | -0.92[2] | -1.82[3] | -2.13[4] | -2.42[5] | -1.13[6] | |
2 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | [7] | 1.08[8] | 1.14[9] | 0.63[10] | 0.97[11] | 0.73[12] | -0.78[13] |
3 | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | [14] | -0.54[15] | -0.75[16] | -0.44[17] | -0.68[18] | -0.66[19] | -1.14[20] |
4 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | -4.64[21] | -4.31[22] | -4.64[23] | -4.13[24] | -3.34[25] | -3.88[26] | |
5 | GNAI2 | Guanine nucleotide-binding protein G(i) subunit alpha-2 | [27] | 0.13[28] | -0.89[29] | -0.75[30] | -0.49[31] | 0.55[32] | 0.27[33] |
6 | AAMP | Angio-associated migratory cell protein | [34] | 0.15[35] | 0.31[36] | 0.28[37] | -1.23[38] | -1.29[39] | 0.08[40] |
7 | GNG12 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 | -4.69[41] | -7.57[42] | 0.34[43] | 1.56[44] | 1.63[45] | 0.94[46] | |
8 | GNAI3 | Guanine nucleotide-binding protein G(k) subunit alpha | [47] | 0.19[48] | 0.78[49] | 0.84[50] | 0.79[51] | 0.39[52] | 0.69[53] |
9 | GNA13 | Guanine nucleotide-binding protein subunit alpha-13 | [54] | 0.18[55] | 0.40[56] | 0.84[57] | 0.87[58] | -0.32[59] | 1.00[60] |
10 | GNA11 | Guanine nucleotide-binding protein subunit alpha-11 | [61] | -0.60[62] | -0.64[63] | -0.72[64] | -1.50[65] | -0.73[66] | -0.80[67] |
11 | MAPK14 | Mitogen-activated protein kinase 14 | [68] | 1.54[69] | 1.65[70] | 1.20[71] | 1.37[72] | 0.81[73] | 1.74[74] |
12 | GNAI1 | Guanine nucleotide-binding protein G(i) subunit alpha-1 | [75] | -1.58[76] | -2.48[77] | -0.37[78] | 0.90[79] | 0.24[80] | 1.29[81] |
13 | GNB5 | Guanine nucleotide-binding protein subunit beta-5 | [82] | 0.16[83] | 0.24[84] | 1.23[85] | 0.47[86] | 0.56[87] | 1.35[88] |
14 | SRC | Proto-oncogene tyrosine-protein kinase Src | [89] | 3.09[90] | 3.12[91] | 2.08[92] | 2.08[93] | 1.23[94] | -0.39[95] |
15 | GNAQ | Guanine nucleotide-binding protein G(q) subunit alpha | [96] | 0.14[97] | 0.96[98] | 1.44[99] | 1.27[100] | 1.46[101] | 1.90[102] |
16 | GNG11 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 | -8.12[103] | -8.07[104] | -7.41[105] | 1.95[106] | 3.23[107] | 2.69[108] | |
17 | GNG7 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 | 1.62[109] | 1.31[110] | 2.09[111] | -2.55[112] | -1.96[113] | 0.48[114] | |
18 | GNG4 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 | 3.53[115] | 1.34[116] | 5.11[117] | 0.94[118] | -1.21[119] | -2.09[120] | |
19 | GNB4 | Guanine nucleotide-binding protein subunit beta-4 | [121] | -0.30[122] | 0.23[123] | 1.20[124] | 2.36[125] | 5.07[126] | 4.55[127] |
20 | GNG2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | -6.21[128] | -7.05[129] | [130] | 2.80[131] | 2.24[132] | 3.24[133] | |
21 | TBXA2R | Thromboxane A2 receptor | [134] | -1.24[135] | -0.69[136] | 0.50[137] | 0.32[138] | -0.26[139] | 3.43[140] |
22 | GNA15 | Guanine nucleotide-binding protein subunit alpha-15 | [141] | -3.32[142] | -4.99[143] | [144] | -6.35[145] | -2.82[146] | 0.56[147] |
23 | GNA14 | Guanine nucleotide-binding protein subunit alpha-14 | [148] | -6.00[149] | -6.34[150] | -5.22[151] | -6.61[152] | -3.55[153] | 3.69[154] |
24 | GNGT2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 | [155] | [156] | [157] | -2.38[158] | -7.09[159] | 0.57[160] | |
25 | GNG3 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 | -0.79[161] | 1.09[162] | -1.17[163] | -1.02[164] | -1.36[165] | 0.38[166] | |
26 | P2RY12 | P2Y purinoceptor 12 | [167] | [168] | [169] | [170] | -4.49[171] | [172] | 3.17[173] |
27 | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 | [174] | 1.65[175] | 3.95[176] | 3.22[177] | 0.69[178] | 3.37[179] | -1.22[180] |
28 | PLA2G4A | Cytosolic phospholipase A2 | [181] | 0.33[182] | -2.18[183] | 5.90[184] | 3.19[185] | 6.92[186] | 4.81[187] |
29 | P2RY1 | P2Y purinoceptor 1 | [188] | [189] | [190] | -0.80[191] | 2.14[192] | 4.38[193] | 6.34[194] |
30 | GNAT3 | Guanine nucleotide-binding protein G(t) subunit alpha-3 | [195] | [196] | [197] | [198] | [199] | [200] | [201] |
31 | GNG13 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 | [202] | [203] | [204] | [205] | [206] | [207] | |
32 | GNG8 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 | [208] | [209] | [210] | [211] | [212] | [213] | |
33 | GNGT1 | Guanine nucleotide-binding protein G(T) subunit gamma-T1 | [214] | [215] | [216] | [217] | [218] | [219] | [220] |