REACTOME_SIGNALING_BY_WNT_IN_CANCER | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CTNNB1 | Catenin beta-1 | [1] | 0.38[2] | 0.19[3] | 0.80[4] | -0.15[5] | 0.16[6] | -0.03[7] |
2 | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isofor | -0.44[8] | -0.29[9] | -0.66[10] | 0.30[11] | -0.28[12] | -0.99[13] | |
3 | PPP2CA | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | -0.96[14] | -0.55[15] | -1.47[16] | -0.16[17] | 0.04[18] | -1.24[19] | |
4 | PPP2CB | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform | -1.63[20] | -1.65[21] | -1.86[22] | -1.36[23] | -1.38[24] | -2.13[25] | |
5 | CTBP1 | C-terminal-binding protein 1 | [26] | -1.18[27] | -0.75[28] | -0.76[29] | -0.50[30] | -1.36[31] | -1.40[32] |
6 | CSNK1A1 | Casein kinase I isoform alpha | [33] | -0.90[34] | -0.59[35] | -1.11[36] | -0.07[37] | 0.11[38] | -0.45[39] |
7 | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform | -2.36[40] | -1.15[41] | -0.72[42] | -1.16[43] | -2.19[44] | -0.50[45] | |
8 | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isofor | -1.54[46] | -0.35[47] | -0.94[48] | 0.03[49] | -0.07[50] | -1.33[51] | |
9 | PPP2R1B | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform | -0.79[52] | -0.99[53] | -0.86[54] | -0.63[55] | -0.77[56] | 1.79[57] | |
10 | LRP5 | Low-density lipoprotein receptor-related protein 5 | [58] | 0.87[59] | 0.91[60] | 1.24[61] | 0.83[62] | -0.54[63] | 1.01[64] |
11 | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform | 0.01[65] | 0.09[66] | -0.64[67] | 0.38[68] | 0.36[69] | -1.41[70] | |
12 | FZD5 | Frizzled-5 | [71] | -0.27[72] | 0.92[73] | 1.62[74] | -2.04[75] | -3.26[76] | 1.45[77] |
13 | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isofor | -1.12[78] | -0.63[79] | -1.38[80] | -0.05[81] | -0.17[82] | -0.94[83] | |
14 | AXIN1 | Axin-1 | [84] | 0.11[85] | 0.75[86] | -1.10[87] | -9.60[88] | -0.67[89] | -1.79[90] |
15 | GSK3B | Glycogen synthase kinase-3 beta | [91] | 0.03[92] | -0.02[93] | 0.27[94] | 0.91[95] | 0.82[96] | 0.02[97] |
16 | RNF43 | E3 ubiquitin-protein ligase RNF43 | [98] | 1.84[99] | 1.27[100] | -0.03[101] | -2.43[102] | -1.18[103] | -0.98[104] |
17 | TNKS2 | Tankyrase-2 | [105] | 0.48[106] | 1.87[107] | 2.05[108] | 1.23[109] | 1.49[110] | 1.28[111] |
18 | FZD4 | Frizzled-4 | [112] | 2.85[113] | 2.11[114] | 0.86[115] | -0.21[116] | -0.79[117] | 1.81[118] |
19 | TCF7L2 | Transcription factor 7-like 2 | [119] | -0.37[120] | 0.71[121] | 0.63[122] | -0.21[123] | -0.14[124] | 0.58[125] |
20 | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform | -0.46[126] | -0.38[127] | -1.31[128] | -0.61[129] | 0.64[130] | -1.04[131] | |
21 | KREMEN1 | Kremen protein 1 | [132] | 1.78[133] | 0.90[134] | 0.68[135] | 0.66[136] | 0.53[137] | -0.79[138] |
22 | DKK1 | Dickkopf-related protein 1 | [139] | 4.04[140] | 0.71[141] | 0.88[142] | 0.43[143] | 3.28[144] | -6.58[145] |
23 | LRP6 | Low-density lipoprotein receptor-related protein 6 | [146] | 0.58[147] | 1.57[148] | 2.63[149] | 0.96[150] | 1.59[151] | 3.64[152] |
24 | TNKS | Tankyrase-1 | [153] | 1.49[154] | 2.14[155] | 2.82[156] | 0.70[157] | 1.82[158] | 2.07[159] |
25 | FZD6 | Frizzled-6 | [160] | 0.55[161] | 1.69[162] | -1.11[163] | 3.83[164] | 2.67[165] | -0.02[166] |
26 | CTBP2 | C-terminal-binding protein 2 | [167] | -3.30[168] | -2.55[169] | 0.89[170] | 2.38[171] | 2.75[172] | 0.41[173] |
27 | APC | Adenomatous polyposis coli protein | [174] | -0.67[175] | 1.32[176] | 0.87[177] | 1.32[178] | 2.04[179] | 2.60[180] |
28 | FZD8 | Frizzled-8 | [181] | -4.36[182] | -9.38[183] | -2.30[184] | -3.87[185] | -2.57[186] | -1.33[187] |
29 | PORCN | Protein-serine O-palmitoleoyltransferase porcupine | [188] | 0.68[189] | -0.52[190] | 0.27[191] | 1.45[192] | 2.50[193] | -0.61[194] |
30 | DKK4 | Dickkopf-related protein 4 | [195] | 0.33[196] | 0.76[197] | [198] | [199] | -8.01[200] | -4.32[201] |
31 | KREMEN2 | Kremen protein 2 | [202] | 6.66[203] | 6.01[204] | 5.94[205] | 2.10[206] | 4.49[207] | -1.94[208] |
32 | WNT3A | Protein Wnt-3a | [209] | [210] | [211] | [212] | [213] | [214] | [215] |
33 | AMER1 | APC membrane recruitment protein 1 | [216] | [217] | [218] | [219] | [220] | [221] | [222] |
34 | DKK2 | Dickkopf-related protein 2 | [223] | [224] | [225] | [226] | [227] | [228] | [229] |