REACTOME_BBSOME_MEDIATED_CARGO_TARGETING_TO_CILIUM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CCT3 T-complex protein 1 subunit gamma [1] 0.24[2] -0.13[3] -0.30[4] 0.29[5] -0.20[6] -0.11[7]
2 CCT8 T-complex protein 1 subunit theta [8] -0.68[9] -0.25[10] 0.03[11] -0.34[12] -0.37[13] -0.61[14]
3 CCT2 T-complex protein 1 subunit beta [15] -0.38[16] -0.16[17] -0.26[18] -0.30[19] -0.35[20] -0.53[21]
4 TCP1 T-complex protein 1 subunit alpha [22] 0.13[23] 0.10[24] 0.09[25] -0.45[26] 0.07[27] -0.05[28]
5 CCT5 T-complex protein 1 subunit epsilon [29] 0.25[30] -0.12[31] -0.19[32] 0.17[33] 0.91[34] 0.14[35]
6 CCT4 T-complex protein 1 subunit delta [36] 0.38[37] 0.48[38] 0.56[39] 0.32[40] -0.18[41] -0.54[42]
7 MKKS McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin [43] -0.21[44] -0.02[45] -0.46[46] -0.54[47] -0.99[48] 0.70[49]
8 BBS5 Bardet-Biedl syndrome 5 protein [50] -1.48[51] -0.90[52] -1.60[53] -1.46[54] -1.47[55] -0.11[56]
9 BBS2 Bardet-Biedl syndrome 2 protein [57] 0.52[58] 0.37[59] -1.30[60] 0.47[61] 0.08[62] 0.83[63]
10 SMO Smoothened homolog [64] 0.83[65] 1.05[66] 1.22[67] 0.94[68] 0.11[69] 1.13[70]
11 BBIP1 BBSome-interacting protein 1 [71] -1.88[72] -0.06[73] -0.71[74] -1.00[75] -0.66[76] 0.10[77]
12 TTC8 Tetratricopeptide repeat protein 8 [78] -0.71[79] -0.04[80] -0.89[81] 0.87[82] -0.01[83] 1.37[84]
13 BBS10 Bardet-Biedl syndrome 10 protein [85] -0.33[86] 0.40[87] 0.01[88] 0.97[89] 0.90[90] 1.45[91]
14 BBS4 Bardet-Biedl syndrome 4 protein [92] -0.07[93] 0.28[94] 1.62[95] 1.08[96] 0.78[97] 1.52[98]
15 BBS7 Bardet-Biedl syndrome 7 protein [99] -0.55[100] -0.16[101] -0.05[102] 0.64[103] 1.57[104] 0.48[105]
16 LZTFL1 Leucine zipper transcription factor-like protein 1 [106] -0.53[107] 0.80[108] 2.09[109] -0.08[110] 0.41[111] 1.97[112]
17 RAB3IP Rab-3A-interacting protein [113] 0.80[114] 1.90[115] 1.70[116] 0.98[117] 0.50[118] 3.49[119]
18 BBS1 Bardet-Biedl syndrome 1 protein [120] 1.08[121] 0.39[122] 1.65[123] 0.97[124] 0.58[125] 2.45[126]
19 ARL6 ADP-ribosylation factor-like protein 6 [127] -2.14[128] -1.87[129] -1.47[130] -1.22[131] -0.44[132] 0.05[133]
20 BBS9 Protein PTHB1 [134] 0.82[135] 0.42[136] 1.12[137] 0.74[138] 0.88[139] 2.65[140]
21 BBS12 Bardet-Biedl syndrome 12 protein [141] -0.69[142] -0.70[143] 0.40[144] 0.49[145] 1.03[146] 1.21[147]
22 MCHR1 Melanin-concentrating hormone receptor 1 [148] 0.05[149] -1.81[150] -4.38[151] -6.42[152] [153] 1.45[154]
23 SSTR3 Somatostatin receptor type 3 [155] 2.42[156] 0.75[157] [158] -4.54[159] [160] -2.63[161]
[1]
ref_hepatocyte CCT3
Mean 86.2
Standard deviation 31
Values 71 1.3e+02 87 87 51
[2]
HepG2 CCT3
Mean 286
Standard deviation 5
Values 2.8e+02 2.9e+02
[3]
HepG2.C3A CCT3
Mean 218
Standard deviation 32
Values 2e+02 2.4e+02
[4]
HuH.7 CCT3
Mean 184
Standard deviation 26
Values 1.9e+02 1.5e+02 2.1e+02
[5]
SNU475 CCT3
Mean 224
Standard deviation 38
Values 2e+02 2.5e+02
[6]
THLE CCT3
Mean 193
Standard deviation 34
Values 1.7e+02 2.2e+02
[7]
liver CCT3
Mean 61.2
Standard deviation 12
Values 60 60 76 48
[8]
ref_hepatocyte CCT8
Mean 67.4
Standard deviation 24
Values 79 99 66 59 34
[9]
HepG2 CCT8
Mean 118
Standard deviation 26
Values 1e+02 1.4e+02
[10]
HepG2.C3A CCT8
Mean 158
Standard deviation 33
Values 1.3e+02 1.8e+02
[11]
HuH.7 CCT8
Mean 180
Standard deviation 17
Values 1.8e+02 1.6e+02 2e+02
[12]
SNU475 CCT8
Mean 113
Standard deviation 13
Values 1e+02 1.2e+02
[13]
THLE CCT8
Mean 134
Standard deviation 11
Values 1.3e+02 1.4e+02
[14]
liver CCT8
Mean 34
Standard deviation 8.1
Values 42 29 40 25
[15]
ref_hepatocyte CCT2
Mean 60.7
Standard deviation 45
Values 48 1.4e+02 54 40 24
[16]
HepG2 CCT2
Mean 131
Standard deviation 14
Values 1.2e+02 1.4e+02
[17]
HepG2.C3A CCT2
Mean 151
Standard deviation 40
Values 1.2e+02 1.8e+02
[18]
HuH.7 CCT2
Mean 133
Standard deviation 26
Values 1.4e+02 1.1e+02 1.6e+02
[19]
SNU475 CCT2
Mean 105
Standard deviation 14
Values 95 1.1e+02
[20]
THLE CCT2
Mean 122
Standard deviation 20
Values 1.1e+02 1.4e+02
[21]
liver CCT2
Mean 32.3
Standard deviation 16
Values 47 22 44 16
[22]
ref_hepatocyte TCP1
Mean 56.7
Standard deviation 20
Values 51 72 81 49 31
[23]
HepG2 TCP1
Mean 174
Standard deviation 17
Values 1.6e+02 1.9e+02
[24]
HepG2.C3A TCP1
Mean 169
Standard deviation 10
Values 1.6e+02 1.8e+02
[25]
HuH.7 TCP1
Mean 159
Standard deviation 25
Values 1.8e+02 1.3e+02 1.7e+02
[26]
SNU475 TCP1
Mean 88.1
Standard deviation 8.4
Values 82 94
[27]
THLE TCP1
Mean 153
Standard deviation 15
Values 1.4e+02 1.6e+02
[28]
liver TCP1
Mean 42
Standard deviation 8.9
Values 48 35 52 34
[29]
ref_hepatocyte CCT5
Mean 55.6
Standard deviation 35
Values 46 1.1e+02 77 32 19
[30]
HepG2 CCT5
Mean 185
Standard deviation 13
Values 1.8e+02 1.9e+02
[31]
HepG2.C3A CCT5
Mean 142
Standard deviation 15
Values 1.3e+02 1.5e+02
[32]
HuH.7 CCT5
Mean 128
Standard deviation 44
Values 1.5e+02 78 1.6e+02
[33]
SNU475 CCT5
Mean 132
Standard deviation 19
Values 1.2e+02 1.5e+02
[34]
THLE CCT5
Mean 268
Standard deviation 57
Values 3.1e+02 2.3e+02
[35]
liver CCT5
Mean 47.2
Standard deviation 9.6
Values 52 47 56 34
[36]
ref_hepatocyte CCT4
Mean 51.5
Standard deviation 23
Values 54 89 47 35 32
[37]
HepG2 CCT4
Mean 187
Standard deviation 3.2
Values 1.8e+02 1.9e+02
[38]
HepG2.C3A CCT4
Mean 199
Standard deviation 20
Values 1.9e+02 2.1e+02
[39]
HuH.7 CCT4
Mean 200
Standard deviation 4.8
Values 2e+02 2e+02 2e+02
[40]
SNU475 CCT4
Mean 136
Standard deviation 8.3
Values 1.3e+02 1.4e+02
[41]
THLE CCT4
Mean 117
Standard deviation 22
Values 1e+02 1.3e+02
[42]
liver CCT4
Mean 27.3
Standard deviation 11
Values 33 20 39 17
[43]
ref_hepatocyte MKKS
Mean 16.2
Standard deviation 4.9
Values 12 11 23 18 17
[44]
HepG2 MKKS
Mean 39.2
Standard deviation 2.8
Values 41 37
[45]
HepG2.C3A MKKS
Mean 44.4
Standard deviation 7.5
Values 39 50
[46]
HuH.7 MKKS
Mean 30.9
Standard deviation 6.8
Values 31 24 38
[47]
SNU475 MKKS
Mean 23.7
Standard deviation 0.47
Values 23 24
[48]
THLE MKKS
Mean 20.9
Standard deviation 2.6
Values 19 23
[49]
liver MKKS
Mean 20.3
Standard deviation 9.1
Values 29 12 28 13
[50]
ref_hepatocyte BBS5
Mean 11.3
Standard deviation 6.5
Values 6.5 5.8 7.5 17 19
[51]
HepG2 BBS5
Mean 11.3
Standard deviation 0.33
Values 12 11
[52]
HepG2.C3A BBS5
Mean 16.8
Standard deviation 4.6
Values 20 14
[53]
HuH.7 BBS5
Mean 9.81
Standard deviation 0.48
Values 9.4 10 9.6
[54]
SNU475 BBS5
Mean 8.72
Standard deviation 0.32
Values 8.5 8.9
[55]
THLE BBS5
Mean 10.5
Standard deviation 0.037
Values 10 10
[56]
liver BBS5
Mean 8.05
Standard deviation 6.6
Values 2.5 15 2.3 12
[57]
ref_hepatocyte BBS2
Mean 4.35
Standard deviation 3.5
Values 11 3.7 2.2 2.4 2.8
[58]
HepG2 BBS2
Mean 17.4
Standard deviation 3
Values 15 20
[59]
HepG2.C3A BBS2
Mean 15.6
Standard deviation 0.73
Values 16 15
[60]
HuH.7 BBS2
Mean 4.65
Standard deviation 0.47
Values 4.5 4.3 5.2
[61]
SNU475 BBS2
Mean 12.7
Standard deviation 5.3
Values 16 9
[62]
THLE BBS2
Mean 11.8
Standard deviation 1.6
Values 13 11
[63]
liver BBS2
Mean 5.95
Standard deviation 1.5
Values 6.9 5.9 7.2 3.9
[64]
ref_hepatocyte SMO
Mean 3.57
Standard deviation 2.2
Values 5.2 1.6 1.1 3.9 6
[65]
HepG2 SMO
Mean 17.8
Standard deviation 4.5
Values 15 21
[66]
HepG2.C3A SMO
Mean 20.5
Standard deviation 5.7
Values 25 16
[67]
HuH.7 SMO
Mean 21.9
Standard deviation 2.6
Values 24 19 23
[68]
SNU475 SMO
Mean 14.5
Standard deviation 3.9
Values 17 12
[69]
THLE SMO
Mean 9.89
Standard deviation 1.3
Values 9 11
[70]
liver SMO
Mean 6.03
Standard deviation 3.6
Values 5 5.8 2.3 11
[71]
ref_hepatocyte BBIP1
Mean 3.3
Standard deviation 1
Values 2.2 2.9 2.7 4.1 4.6
[72]
HepG2 BBIP1
Mean 2.51
Standard deviation 0.011
Values 2.5 2.5
[73]
HepG2.C3A BBIP1
Mean 8.77
Standard deviation 1.4
Values 7.8 9.8
[74]
HuH.7 BBIP1
Mean 5.3
Standard deviation 0.43
Values 4.8 5.5 5.6
[75]
SNU475 BBIP1
Mean 3.48
Standard deviation 0.29
Values 3.7 3.3
[76]
THLE BBIP1
Mean 5.35
Standard deviation 0.28
Values 5.5 5.1
[77]
liver BBIP1
Mean 2.73
Standard deviation 1.3
Values 3.6 1.7 4.1 1.5
[78]
ref_hepatocyte TTC8
Mean 2.8
Standard deviation 1.1
Values 2.6 3.4 1.3 4.3 2.5
[79]
HepG2 TTC8
Mean 4.8
Standard deviation 0.34
Values 4.6 5
[80]
HepG2.C3A TTC8
Mean 7.58
Standard deviation 1.2
Values 6.7 8.4
[81]
HuH.7 TTC8
Mean 3.98
Standard deviation 0.24
Values 3.7 4.1 4.1
[82]
SNU475 TTC8
Mean 10.9
Standard deviation 1
Values 12 10
[83]
THLE TTC8
Mean 7.14
Standard deviation 1.3
Values 6.2 8
[84]
liver TTC8
Mean 5.56
Standard deviation 2
Values 5.9 5.6 7.8 3
[85]
ref_hepatocyte BBS10
Mean 2.35
Standard deviation 0.96
Values 2 3.5 2.5 0.94 2.7
[86]
HepG2 BBS10
Mean 5.22
Standard deviation 1.1
Values 4.4 6
[87]
HepG2.C3A BBS10
Mean 8.62
Standard deviation 2.7
Values 6.7 10
[88]
HuH.7 BBS10
Mean 6.2
Standard deviation 0.79
Values 6.9 5.3 6.4
[89]
SNU475 BBS10
Mean 9.71
Standard deviation 0.55
Values 10 9.3
[90]
THLE BBS10
Mean 11.2
Standard deviation 0.3
Values 11 11
[91]
liver BBS10
Mean 4.93
Standard deviation 1.5
Values 4.3 4.9 7 3.6
[92]
ref_hepatocyte BBS4
Mean 2.09
Standard deviation 0.83
Values 1.1 1.6 3.2 2 2.6
[93]
HepG2 BBS4
Mean 5.57
Standard deviation 0.61
Values 5.1 6
[94]
HepG2.C3A BBS4
Mean 7.07
Standard deviation 0.95
Values 6.4 7.7
[95]
HuH.7 BBS4
Mean 16.9
Standard deviation 3.7
Values 15 14 21
[96]
SNU475 BBS4
Mean 9.37
Standard deviation 1.5
Values 10 8.3
[97]
THLE BBS4
Mean 9.27
Standard deviation 0.16
Values 9.2 9.4
[98]
liver BBS4
Mean 4.6
Standard deviation 1.9
Values 4.9 3.6 7.1 2.8
[99]
ref_hepatocyte BBS7
Mean 2.06
Standard deviation 1.7
Values 2.3 4.7 2.3 0.7 0.31
[100]
HepG2 BBS7
Mean 3.94
Standard deviation 0.29
Values 3.7 4.1
[101]
HepG2.C3A BBS7
Mean 5.1
Standard deviation 0.79
Values 4.5 5.7
[102]
HuH.7 BBS7
Mean 5.23
Standard deviation 0.85
Values 5.9 4.3 5.5
[103]
SNU475 BBS7
Mean 6.8
Standard deviation 0.31
Values 7 6.6
[104]
THLE BBS7
Mean 15.7
Standard deviation 3.2
Values 18 13
[105]
liver BBS7
Mean 2.21
Standard deviation 0.43
Values 1.9 2.3 2.8 1.9
[106]
ref_hepatocyte LZTFL1
Mean 1.79
Standard deviation 1.2
Values 0.38 0.69 2.4 2.8 2.7
[107]
HepG2 LZTFL1
Mean 3.46
Standard deviation 0.75
Values 2.9 4
[108]
HepG2.C3A LZTFL1
Mean 8.65
Standard deviation 0.18
Values 8.8 8.5
[109]
HuH.7 LZTFL1
Mean 20
Standard deviation 0.84
Values 20 20 19
[110]
SNU475 LZTFL1
Mean 3.6
Standard deviation 0.5
Values 3.9 3.2
[111]
THLE LZTFL1
Mean 6.14
Standard deviation 0.51
Values 5.8 6.5
[112]
liver LZTFL1
Mean 5.4
Standard deviation 1.3
Values 4.8 5 7.4 4.5
[113]
ref_hepatocyte RAB3IP
Mean 1.38
Standard deviation 0.51
Values 2.1 1.6 1.3 0.9 0.97
[114]
HepG2 RAB3IP
Mean 6.73
Standard deviation 2
Values 5.3 8.2
[115]
HepG2.C3A RAB3IP
Mean 14.3
Standard deviation 1.8
Values 13 16
[116]
HuH.7 RAB3IP
Mean 11.8
Standard deviation 0.87
Values 13 12 11
[117]
SNU475 RAB3IP
Mean 5.76
Standard deviation 0.015
Values 5.8 5.8
[118]
THLE RAB3IP
Mean 5.02
Standard deviation 0.036
Values 5 5
[119]
liver RAB3IP
Mean 11.9
Standard deviation 2
Values 13 14 9.3 11
[120]
ref_hepatocyte BBS1
Mean 1.32
Standard deviation 0.71
Values 0.84 0.94 0.66 2.2 2
[121]
HepG2 BBS1
Mean 7.84
Standard deviation 0.53
Values 8.2 7.5
[122]
HepG2.C3A BBS1
Mean 4.8
Standard deviation 0.15
Values 4.9 4.7
[123]
HuH.7 BBS1
Mean 10.9
Standard deviation 2.2
Values 12 8.4 12
[124]
SNU475 BBS1
Mean 5.49
Standard deviation 1.5
Values 6.6 4.4
[125]
THLE BBS1
Mean 5.06
Standard deviation 0.86
Values 5.7 4.5
[126]
liver BBS1
Mean 5.54
Standard deviation 1.4
Values 4.9 5.3 7.6 4.4
[127]
ref_hepatocyte ARL6
Mean 0.946
Standard deviation 0.53
Values 1.1 1 1.6 0.74 0.18
[128]
HepG2 ARL6
Mean 0.603
Standard deviation 0.17
Values 0.48 0.73
[129]
HepG2.C3A ARL6
Mean 0.719
Standard deviation 0.44
Values 0.41 1
[130]
HuH.7 ARL6
Mean 0.897
Standard deviation 0.3
Values 1.1 1 0.55
[131]
SNU475 ARL6
Mean 0.861
Standard deviation 0.36
Values 0.61 1.1
[132]
THLE ARL6
Mean 1.79
Standard deviation 0.00045
Values 1.8 1.8
[133]
liver ARL6
Mean 0.755
Standard deviation 0.2
Values 0.63 0.68 1.1 0.65
[134]
ref_hepatocyte BBS9
Mean 0.724
Standard deviation 0.25
Values 0.84 0.63 0.45 0.61 1.1
[135]
HepG2 BBS9
Mean 3.57
Standard deviation 0.7
Values 3.1 4.1
[136]
HepG2.C3A BBS9
Mean 2.69
Standard deviation 0.99
Values 3.4 2
[137]
HuH.7 BBS9
Mean 4.12
Standard deviation 0.66
Values 3.8 4.9 3.7
[138]
SNU475 BBS9
Mean 2.56
Standard deviation 0.49
Values 2.9 2.2
[139]
THLE BBS9
Mean 3.43
Standard deviation 0.059
Values 3.4 3.5
[140]
liver BBS9
Mean 3.5
Standard deviation 1.7
Values 2.1 5.2 2.1 4.6
[141]
ref_hepatocyte BBS12
Mean 0.403
Standard deviation 0.16
Values 0.25 0.65 0.35 0.3 0.46
[142]
HepG2 BBS12
Mean 0.698
Standard deviation 0.15
Values 0.59 0.81
[143]
HepG2.C3A BBS12
Mean 0.688
Standard deviation 0.0027
Values 0.69 0.69
[144]
HuH.7 BBS12
Mean 1.4
Standard deviation 0.86
Values 0.99 2.4 0.82
[145]
SNU475 BBS12
Mean 1.2
Standard deviation 0.075
Values 1.3 1.1
[146]
THLE BBS12
Mean 2.12
Standard deviation 0.12
Values 2 2.2
[147]
liver BBS12
Mean 0.719
Standard deviation 0.2
Values 0.71 1 0.62 0.56
[148]
ref_hepatocyte MCHR1
Mean 0.307
Standard deviation 0.44
Values 0 0 0 0.93 0.6
[149]
HepG2 MCHR1
Mean 0.89
Standard deviation 0.021
Values 0.91 0.88
[150]
HepG2.C3A MCHR1
Mean 0.244
Standard deviation 0.11
Values 0.17 0.32
[151]
HuH.7 MCHR1
Mean 0.0386
Standard deviation 0.023
Values 0.025 0.026 0.066
[152]
SNU475 MCHR1
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[153]
THLE MCHR1
Mean 0
Standard deviation 0
Values 0 0
[154]
liver MCHR1
Mean 0.645
Standard deviation 0.18
Values 0.45 0.81 0.54 0.78
[155]
ref_hepatocyte SSTR3
Mean 0.0555
Standard deviation 0.12
Values 0.28 0 0 0 0
[156]
HepG2 SSTR3
Mean 0.83
Standard deviation 0.7
Values 0.34 1.3
[157]
HepG2.C3A SSTR3
Mean 0.26
Standard deviation 0.13
Values 0.17 0.35
[158]
HuH.7 SSTR3
Mean 0
Standard deviation 0
Values 0 0 0
[159]
SNU475 SSTR3
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[160]
THLE SSTR3
Mean 0
Standard deviation 0
Values 0 0
[161]
liver SSTR3
Mean 0.00688
Standard deviation 0.008
Values 0 0.014 0 0.013