REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX_IN_CANCER Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A [1] -1.13[2] -1.14[3] -2.07[4] -0.92[5] -1.71[6] -1.53[7]
2 TGFBR2 TGF-beta receptor type-2 [8] 1.81[9] 1.66[10] 1.95[11] 0.40[12] 1.75[13] 1.34[14]
3 SMAD3 Mothers against decapentaplegic homolog 3 [15] 0.92[16] 0.70[17] 1.57[18] 1.14[19] 1.65[20] 0.05[21]
4 TGFBR1 TGF-beta receptor type-1 [22] -0.68[23] -0.07[24] 0.07[25] -0.32[26] 0.42[27] 1.17[28]
5 SMAD4 Mothers against decapentaplegic homolog 4 [29] 0.38[30] 1.40[31] 2.00[32] 1.25[33] 1.24[34] 2.63[35]
6 SMAD2 Mothers against decapentaplegic homolog 2 [36] 1.01[37] 1.65[38] 1.79[39] 1.72[40] 1.54[41] 2.41[42]
7 TGFB1 Transforming growth factor beta-1 [43] 2.46[44] 1.81[45] -0.30[46] 3.18[47] 2.04[48] -1.39[49]
8 ZFYVE9 Zinc finger FYVE domain-containing protein 9 [50] 0.63[51] 1.25[52] 1.84[53] 0.94[54] 1.02[55] 2.04[56]
[1]
ref_hepatocyte FKBP1A
Mean 84.3
Standard deviation 51
Values 1.4e+02 1.4e+02 61 46 37
[2]
HepG2 FKBP1A
Mean 172
Standard deviation 7.9
Values 1.8e+02 1.7e+02
[3]
HepG2.C3A FKBP1A
Mean 116
Standard deviation 13
Values 1.1e+02 1.2e+02
[4]
HuH.7 FKBP1A
Mean 37.6
Standard deviation 14
Values 42 22 49
[5]
SNU475 FKBP1A
Mean 129
Standard deviation 5.7
Values 1.3e+02 1.3e+02
[6]
THLE FKBP1A
Mean 109
Standard deviation 15
Values 98 1.2e+02
[7]
liver FKBP1A
Mean 46.2
Standard deviation 42
Values 77 10 88 9.1
[8]
ref_hepatocyte TGFBR2
Mean 11.1
Standard deviation 9.7
Values 26 15 6.4 4.2 3.5
[9]
HepG2 TGFBR2
Mean 172
Standard deviation 10
Values 1.7e+02 1.8e+02
[10]
HepG2.C3A TGFBR2
Mean 106
Standard deviation 5.8
Values 1.1e+02 1e+02
[11]
HuH.7 TGFBR2
Mean 80.1
Standard deviation 11
Values 92 71 77
[12]
SNU475 TGFBR2
Mean 42.5
Standard deviation 18
Values 29 55
[13]
THLE TGFBR2
Mean 157
Standard deviation 23
Values 1.4e+02 1.7e+02
[14]
liver TGFBR2
Mean 44.6
Standard deviation 11
Values 31 51 40 57
[15]
ref_hepatocyte SMAD3
Mean 5.99
Standard deviation 4.6
Values 4.8 8.4 13 1.9 2.2
[16]
HepG2 SMAD3
Mean 50.4
Standard deviation 14
Values 60 40
[17]
HepG2.C3A SMAD3
Mean 29.5
Standard deviation 11
Values 37 22
[18]
HuH.7 SMAD3
Mean 33.2
Standard deviation 6.9
Values 31 41 28
[19]
SNU475 SMAD3
Mean 38.2
Standard deviation 2.7
Values 40 36
[20]
THLE SMAD3
Mean 78.9
Standard deviation 8.4
Values 73 85
[21]
liver SMAD3
Mean 9.85
Standard deviation 3
Values 12 7.4 7.1 13
[22]
ref_hepatocyte TGFBR1
Mean 4.72
Standard deviation 3.6
Values 4.2 11 3.6 1.8 3.1
[23]
HepG2 TGFBR1
Mean 13.1
Standard deviation 3.3
Values 11 15
[24]
HepG2.C3A TGFBR1
Mean 13.6
Standard deviation 0.22
Values 13 14
[25]
HuH.7 TGFBR1
Mean 9.25
Standard deviation 2.6
Values 8.3 12 7.2
[26]
SNU475 TGFBR1
Mean 11
Standard deviation 1.8
Values 9.7 12
[27]
THLE TGFBR1
Mean 26.5
Standard deviation 5.3
Values 30 23
[28]
liver TGFBR1
Mean 16.9
Standard deviation 7.4
Values 8.6 25 13 20
[29]
ref_hepatocyte SMAD4
Mean 3.16
Standard deviation 0.71
Values 2.9 2.8 4.2 2.4 3.4
[30]
HepG2 SMAD4
Mean 18.3
Standard deviation 3.2
Values 16 21
[31]
HepG2.C3A SMAD4
Mean 25.2
Standard deviation 3
Values 27 23
[32]
HuH.7 SMAD4
Mean 23.6
Standard deviation 3.4
Values 24 27 20
[33]
SNU475 SMAD4
Mean 21.8
Standard deviation 2.7
Values 24 20
[34]
THLE SMAD4
Mean 31.4
Standard deviation 1.4
Values 30 32
[35]
liver SMAD4
Mean 31
Standard deviation 13
Values 23 40 16 44
[36]
ref_hepatocyte SMAD2
Mean 2.54
Standard deviation 1.2
Values 4.5 2.8 1.9 1.9 1.6
[37]
HepG2 SMAD2
Mean 22.7
Standard deviation 2.3
Values 21 24
[38]
HepG2.C3A SMAD2
Mean 24.2
Standard deviation 1.1
Values 25 23
[39]
HuH.7 SMAD2
Mean 16.4
Standard deviation 1.6
Values 17 18 15
[40]
SNU475 SMAD2
Mean 24.3
Standard deviation 3.3
Values 27 22
[41]
THLE SMAD2
Mean 31
Standard deviation 0.65
Values 31 32
[42]
liver SMAD2
Mean 21.4
Standard deviation 6.7
Values 17 29 15 25
[43]
ref_hepatocyte TGFB1
Mean 2.22
Standard deviation 1.8
Values 5.3 1.3 0.92 1.3 2.3
[44]
HepG2 TGFB1
Mean 54.4
Standard deviation 32
Values 77 32
[45]
HepG2.C3A TGFB1
Mean 23.6
Standard deviation 8.3
Values 29 18
[46]
HuH.7 TGFB1
Mean 3.37
Standard deviation 1.4
Values 4.5 1.8 3.7
[47]
SNU475 TGFB1
Mean 58.3
Standard deviation 7.8
Values 64 53
[48]
THLE TGFB1
Mean 38.3
Standard deviation 9.8
Values 31 45
[49]
liver TGFB1
Mean 1.34
Standard deviation 0.71
Values 1.1 1.4 0.62 2.3
[50]
ref_hepatocyte ZFYVE9
Mean 1.96
Standard deviation 0.58
Values 3 1.6 1.8 1.5 1.9
[51]
HepG2 ZFYVE9
Mean 13.5
Standard deviation 4
Values 11 16
[52]
HepG2.C3A ZFYVE9
Mean 14.2
Standard deviation 1.5
Values 13 15
[53]
HuH.7 ZFYVE9
Mean 13.2
Standard deviation 2.5
Values 16 13 11
[54]
SNU475 ZFYVE9
Mean 10.9
Standard deviation 1.4
Values 12 10
[55]
THLE ZFYVE9
Mean 16.8
Standard deviation 0.22
Values 17 17
[56]
liver ZFYVE9
Mean 12.8
Standard deviation 11
Values 4.9 25 1.8 20