REACTOME_SIGNALING_BY_SCF_KIT Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RAC1 Ras-related C3 botulinum toxin substrate 1 [1] -1.09[2] -1.22[3] -0.83[4] -0.97[5] -0.63[6] -1.97[7]
2 STAT3 Signal transducer and activator of transcription 3 [8] -0.14[9] -1.45[10] -1.03[11] -0.74[12] -1.11[13] 1.40[14]
3 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [15] -0.25[16] 0.38[17] 0.02[18] -0.10[19] 0.90[20] 0.25[21]
4 GRB2 Growth factor receptor-bound protein 2 [22] 0.50[23] 0.53[24] 0.34[25] -0.43[26] -0.16[27] -0.71[28]
5 YES1 Tyrosine-protein kinase Yes [29] -1.56[30] 0.13[31] 0.04[32] -0.54[33] -0.71[34] -0.88[35]
6 STAT1 Signal transducer and activator of transcription 1-alpha/beta [36] -0.77[37] -1.49[38] -0.70[39] 1.54[40] -0.36[41] -0.05[42]
7 NRAS GTPase NRas [43] -0.07[44] 0.56[45] 0.66[46] 0.01[47] -0.06[48] -1.26[49]
8 HRAS GTPase HRas [50] -1.70[51] -2.21[52] -3.32[53] -1.94[54] -1.79[55] -3.67[56]
9 KRAS GTPase KRas [57] -1.21[58] -1.03[59] 0.25[60] -0.19[61] -0.17[62] -0.33[63]
10 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [64] -1.17[65] -0.85[66] -0.08[67] 1.08[68] 0.94[69] 2.00[70]
11 SOS1 Son of sevenless homolog 1 [71] -0.79[72] 0.93[73] 0.12[74] -0.14[75] -0.55[76] -0.47[77]
12 LYN Tyrosine-protein kinase Lyn [78] -1.56[79] -1.54[80] -1.32[81] 0.07[82] -0.81[83] -0.99[84]
13 PTPN6 Tyrosine-protein phosphatase non-receptor type 6 [85] -1.16[86] -0.77[87] -0.51[88] -8.13[89] -2.75[90] -1.18[91]
14 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta [92] 1.18[93] 1.60[94] 1.89[95] -0.28[96] 0.64[97] -1.29[98]
15 STAT5B Signal transducer and activator of transcription 5B [99] 0.66[100] 0.49[101] 0.87[102] 0.56[103] 0.06[104] 0.62[105]
16 SOCS6 Suppressor of cytokine signaling 6 [106] -0.33[107] 0.71[108] -0.57[109] 0.34[110] 0.32[111] 0.82[112]
17 GRB10 Growth factor receptor-bound protein 10 [113] 1.81[114] -1.07[115] 0.99[116] -0.30[117] 0.93[118] 0.94[119]
18 SRC Proto-oncogene tyrosine-protein kinase Src [120] 2.33[121] 2.51[122] 1.19[123] 1.41[124] 0.95[125] -1.85[126]
19 FES Tyrosine-protein kinase Fes/Fps [127] 0.08[128] -1.71[129] -1.67[130] -7.60[131] -2.95[132] 0.18[133]
20 SH2B3 SH2B adapter protein 3 [134] 0.42[135] 0.21[136] 0.11[137] 0.57[138] 1.76[139] 0.40[140]
21 PRKCA Protein kinase C alpha type [141] 2.14[142] 2.38[143] 2.42[144] 1.16[145] 1.88[146] 0.91[147]
22 CHEK1 Serine/threonine-protein kinase Chk1 [148] 0.84[149] 1.40[150] 0.65[151] 1.16[152] 1.75[153] -3.03[154]
23 STAT5A Signal transducer and activator of transcription 5A [155] -2.64[156] -1.27[157] -2.52[158] -1.83[159] -0.71[160] -0.77[161]
24 SOCS1 Suppressor of cytokine signaling 1 [162] -2.14[163] -1.08[164] -1.13[165] -2.78[166] -3.80[167] -2.47[168]
25 FYN Tyrosine-protein kinase Fyn [169] 0.25[170] -8.16[171] 0.09[172] 0.48[173] 2.37[174] -0.03[175]
26 PTPRU Receptor-type tyrosine-protein phosphatase U [176] 3.48[177] 1.59[178] 1.16[179] -2.56[180] 0.22[181] 0.62[182]
27 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform -1.07[183] 0.76[184] 0.63[185] 0.14[186] 0.71[187] 0.91[188]
28 GRB7 Growth factor receptor-bound protein 7 [189] 1.71[190] 2.23[191] -0.92[192] -3.64[193] -2.55[194] -1.33[195]
29 GAB2 GRB2-associated-binding protein 2 [196] 0.87[197] 0.85[198] 0.78[199] -0.06[200] 0.38[201] -0.46[202]
30 FER Tyrosine-protein kinase Fer [203] -1.00[204] -0.24[205] -1.57[206] -0.49[207] -0.09[208] 0.41[209]
31 MMP9 Matrix metalloproteinase-9 [210] -3.41[211] -4.27[212] -6.98[213] -2.42[214] -4.62[215] -1.14[216]
32 JAK2 Tyrosine-protein kinase JAK2 [217] -0.47[218] -0.28[219] -1.04[220] -0.22[221] 0.73[222] 1.70[223]
33 TEC Tyrosine-protein kinase Tec [224] -2.85[225] -3.05[226] -2.77[227] 0.35[228] -0.87[229] 0.59[230]
34 CBL E3 ubiquitin-protein ligase CBL [231] 3.75[232] 2.90[233] 2.80[234] 4.15[235] 3.99[236] 2.75[237]
35 VAV1 Proto-oncogene vav [238] -9.19[239] -4.17[240] -6.19[241] -7.07[242] -7.98[243] 0.18[244]
36 PIK3R3 Phosphatidylinositol 3-kinase regulatory subunit gamma [245] 1.03[246] 1.23[247] 1.76[248] 2.18[249] 1.56[250] 1.67[251]
37 GRAP GRB2-related adapter protein [252] 3.11[253] 0.43[254] -5.15[255] -4.03[256] -2.45[257] 0.82[258]
38 LCK Tyrosine-protein kinase Lck [259] 2.08[260] 2.36[261] -7.95[262] -6.07[263] -5.91[264] 0.23[265]
39 CMA1 Chymase [266] -5.53[267] -7.12[268] [269] -8.72[270] [271] -3.37[272]
40 SH2B2 SH2B adapter protein 2 [273] -0.69[274] -1.15[275] -0.65[276] -0.45[277] -0.78[278] -2.12[279]
41 KITLG Kit ligand [280] 4.75[281] 1.17[282] 6.58[283] 5.74[284] 4.30[285] 2.03[286]
42 KIT Mast/stem cell growth factor receptor Kit [287] -3.68[288] -5.37[289] [290] 1.51[291] -3.66[292] 2.63[293]
43 GRAP2 GRB2-related adapter protein 2 [294] -6.54[295] [296] -3.05[297] -2.96[298] -1.57[299] -0.17[300]
[1]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 28 59 81 45 47
[2]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 89 86
[3]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 67 57
[4]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[5]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 89 1e+02
[6]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[7]
liver RAC1
Mean 37.8
Standard deviation 32
Values 63 12 67 9.5
[8]
ref_hepatocyte STAT3
Mean 30.1
Standard deviation 11
Values 26 25 18 46 36
[9]
HepG2 STAT3
Mean 97.5
Standard deviation 10
Values 90 1e+02
[10]
HepG2.C3A STAT3
Mean 30.7
Standard deviation 5.2
Values 34 27
[11]
HuH.7 STAT3
Mean 49.1
Standard deviation 15
Values 47 65 35
[12]
SNU475 STAT3
Mean 65.4
Standard deviation 12
Values 74 57
[13]
THLE STAT3
Mean 44.3
Standard deviation 6
Values 40 49
[14]
liver STAT3
Mean 227
Standard deviation 42
Values 1.9e+02 2.3e+02 2.8e+02 2e+02
[15]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 33 53 10 7.5 7.4
[16]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 58 76
[17]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 68 92
[18]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 86 77 61
[19]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 75 76
[20]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[21]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 60 99 62 80
[22]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[23]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[24]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[25]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[26]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[27]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[28]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[29]
ref_hepatocyte YES1
Mean 20.5
Standard deviation 18
Values 40 40 7.9 6.7 7.6
[30]
HepG2 YES1
Mean 24.9
Standard deviation 6
Values 21 29
[31]
HepG2.C3A YES1
Mean 62.3
Standard deviation 7.4
Values 57 68
[32]
HuH.7 YES1
Mean 69.8
Standard deviation 10
Values 74 77 58
[33]
SNU475 YES1
Mean 51.4
Standard deviation 2.5
Values 53 50
[34]
THLE YES1
Mean 39.7
Standard deviation 2
Values 41 38
[35]
liver YES1
Mean 31.7
Standard deviation 8
Values 27 39 23 38
[36]
ref_hepatocyte STAT1
Mean 20.3
Standard deviation 8.7
Values 17 35 19 12 18
[37]
HepG2 STAT1
Mean 42.7
Standard deviation 9.4
Values 36 49
[38]
HepG2.C3A STAT1
Mean 20.1
Standard deviation 7.2
Values 15 25
[39]
HuH.7 STAT1
Mean 41.6
Standard deviation 4.5
Values 47 38 40
[40]
SNU475 STAT1
Mean 216
Standard deviation 1.4e+02
Values 3.2e+02 1.1e+02
[41]
THLE STAT1
Mean 50.3
Standard deviation 2.1
Values 49 52
[42]
liver STAT1
Mean 55.8
Standard deviation 15
Values 49 69 67 38
[43]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[44]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[45]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[46]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[47]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[48]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[49]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[50]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[51]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[52]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[53]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[54]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[55]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[56]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[57]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[58]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[59]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[60]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[61]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[62]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[63]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[64]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.1 7.4 4.2 8.1 14
[65]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 9.8 14
[66]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 9.6 13
[67]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 23 32 15
[68]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 80 35
[69]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[70]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 64 1e+02 32 1.4e+02
[71]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 27 1.9 2.2 1.3 1.5
[72]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 9.4 19
[73]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 39 33
[74]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 22 37 15
[75]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 25 20
[76]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[77]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 13 18 9.3 16
[78]
ref_hepatocyte LYN
Mean 5.33
Standard deviation 4.4
Values 0.29 6.8 12 3.7 3.8
[79]
HepG2 LYN
Mean 6.48
Standard deviation 1
Values 5.8 7.2
[80]
HepG2.C3A LYN
Mean 5.11
Standard deviation 2.1
Values 3.6 6.6
[81]
HuH.7 LYN
Mean 7.08
Standard deviation 0.67
Values 7.4 7.5 6.3
[82]
SNU475 LYN
Mean 20.4
Standard deviation 4.4
Values 17 23
[83]
THLE LYN
Mean 9.65
Standard deviation 1.4
Values 8.7 11
[84]
liver LYN
Mean 7.66
Standard deviation 1.7
Values 7.2 9.4 5.5 8.6
[85]
ref_hepatocyte PTPN6
Mean 5.33
Standard deviation 3
Values 2.2 3.1 4.4 7.6 9.3
[86]
HepG2 PTPN6
Mean 8.54
Standard deviation 0.054
Values 8.5 8.6
[87]
HepG2.C3A PTPN6
Mean 8.69
Standard deviation 0.18
Values 8.6 8.8
[88]
HuH.7 PTPN6
Mean 12.4
Standard deviation 1.9
Values 13 10 14
[89]
SNU475 PTPN6
Mean 0.0694
Standard deviation 0.026
Values 0.088 0.051
[90]
THLE PTPN6
Mean 2.52
Standard deviation 0.67
Values 2 3
[91]
liver PTPN6
Mean 6.69
Standard deviation 2
Values 7.5 4.8 9.1 5.4
[92]
ref_hepatocyte PIK3R2
Mean 5.25
Standard deviation 3.4
Values 11 3.2 3.1 4.9 3.8
[93]
HepG2 PIK3R2
Mean 42.5
Standard deviation 2.8
Values 44 41
[94]
HepG2.C3A PIK3R2
Mean 44.2
Standard deviation 13
Values 53 35
[95]
HuH.7 PIK3R2
Mean 64.7
Standard deviation 10
Values 75 55 64
[96]
SNU475 PIK3R2
Mean 15.7
Standard deviation 3.3
Values 18 13
[97]
THLE PIK3R2
Mean 26
Standard deviation 2.8
Values 24 28
[98]
liver PIK3R2
Mean 6.1
Standard deviation 1.7
Values 7.6 6 3.8 6.9
[99]
ref_hepatocyte STAT5B
Mean 3.99
Standard deviation 1.3
Values 4.1 3.3 2.3 4.6 5.6
[100]
HepG2 STAT5B
Mean 22.6
Standard deviation 6.3
Values 27 18
[101]
HepG2.C3A STAT5B
Mean 15.5
Standard deviation 4
Values 18 13
[102]
HuH.7 STAT5B
Mean 24.2
Standard deviation 2.2
Values 25 22 26
[103]
SNU475 STAT5B
Mean 21.5
Standard deviation 4
Values 24 19
[104]
THLE STAT5B
Mean 13.3
Standard deviation 0.2
Values 13 13
[105]
liver STAT5B
Mean 17.5
Standard deviation 4.7
Values 13 21 14 22
[106]
ref_hepatocyte SOCS6
Mean 3.82
Standard deviation 2.2
Values 3.9 7.5 2.4 2.5 2.7
[107]
HepG2 SOCS6
Mean 10.8
Standard deviation 2.5
Values 9.1 13
[108]
HepG2.C3A SOCS6
Mean 17.4
Standard deviation 1.2
Values 18 17
[109]
HuH.7 SOCS6
Mean 8.58
Standard deviation 0.94
Values 8.8 9.4 7.6
[110]
SNU475 SOCS6
Mean 17.6
Standard deviation 0.84
Values 17 18
[111]
THLE SOCS6
Mean 15.1
Standard deviation 1.1
Values 14 16
[112]
liver SOCS6
Mean 19.3
Standard deviation 6.3
Values 15 24 13 26
[113]
ref_hepatocyte GRB10
Mean 3.75
Standard deviation 1.1
Values 2 3.4 4.9 4.1 4.3
[114]
HepG2 GRB10
Mean 47
Standard deviation 17
Values 59 35
[115]
HepG2.C3A GRB10
Mean 4.96
Standard deviation 0.92
Values 5.6 4.3
[116]
HuH.7 GRB10
Mean 24.7
Standard deviation 7
Values 22 33 19
[117]
SNU475 GRB10
Mean 11.1
Standard deviation 1.2
Values 12 10
[118]
THLE GRB10
Mean 22.6
Standard deviation 0.57
Values 22 23
[119]
liver GRB10
Mean 20.5
Standard deviation 8.3
Values 22 21 9.1 29
[120]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[121]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[122]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[123]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[124]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[125]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[126]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[127]
ref_hepatocyte FES
Mean 3.44
Standard deviation 3.5
Values 2.1 0.42 1.4 3.9 9.3
[128]
HepG2 FES
Mean 13
Standard deviation 1.1
Values 12 14
[129]
HepG2.C3A FES
Mean 2.91
Standard deviation 1.3
Values 2 3.8
[130]
HuH.7 FES
Mean 3.58
Standard deviation 0.35
Values 3.6 3.2 3.9
[131]
SNU475 FES
Mean 0.0644
Standard deviation 0.045
Values 0.032 0.096
[132]
THLE FES
Mean 1.41
Standard deviation 0.092
Values 1.3 1.5
[133]
liver FES
Mean 11.1
Standard deviation 3.5
Values 16 7.9 9.8 10
[134]
ref_hepatocyte SH2B3
Mean 3.01
Standard deviation 1.8
Values 1.5 5.4 4.5 2.2 1.4
[135]
HepG2 SH2B3
Mean 14.4
Standard deviation 3.2
Values 17 12
[136]
HepG2.C3A SH2B3
Mean 9.65
Standard deviation 3.7
Values 12 7
[137]
HuH.7 SH2B3
Mean 10.8
Standard deviation 1.3
Values 12 9.4 11
[138]
SNU475 SH2B3
Mean 16.2
Standard deviation 14
Values 6.5 26
[139]
THLE SH2B3
Mean 32.3
Standard deviation 2
Values 34 31
[140]
liver SH2B3
Mean 11.3
Standard deviation 4.4
Values 11 13 5.4 16
[141]
ref_hepatocyte PRKCA
Mean 2.45
Standard deviation 2.1
Values 2.7 6 1.1 1.2 1.2
[142]
HepG2 PRKCA
Mean 38.7
Standard deviation 5.6
Values 35 43
[143]
HepG2.C3A PRKCA
Mean 35.5
Standard deviation 4.5
Values 32 39
[144]
HuH.7 PRKCA
Mean 43.7
Standard deviation 11
Values 54 44 33
[145]
SNU475 PRKCA
Mean 20
Standard deviation 4.3
Values 17 23
[146]
THLE PRKCA
Mean 28.8
Standard deviation 11
Values 21 36
[147]
liver PRKCA
Mean 13.2
Standard deviation 7.1
Values 11 17 4.7 21
[148]
ref_hepatocyte CHEK1
Mean 2.44
Standard deviation 1.9
Values 3.2 5.4 1.9 0.69 0.99
[149]
HepG2 CHEK1
Mean 15.6
Standard deviation 7.2
Values 11 21
[150]
HepG2.C3A CHEK1
Mean 17.9
Standard deviation 12
Values 9.6 26
[151]
HuH.7 CHEK1
Mean 12.7
Standard deviation 5.1
Values 15 6.8 16
[152]
SNU475 CHEK1
Mean 19.9
Standard deviation 4.6
Values 17 23
[153]
THLE CHEK1
Mean 26.2
Standard deviation 4.4
Values 23 29
[154]
liver CHEK1
Mean 0.851
Standard deviation 0.2
Values 0.73 1 1 0.64
[155]
ref_hepatocyte STAT5A
Mean 2.36
Standard deviation 1.6
Values 1.8 2.7 5 1.5 0.95
[156]
HepG2 STAT5A
Mean 1.35
Standard deviation 0.098
Values 1.4 1.3
[157]
HepG2.C3A STAT5A
Mean 2.72
Standard deviation 0.23
Values 2.6 2.9
[158]
HuH.7 STAT5A
Mean 1.37
Standard deviation 0.38
Values 1.1 1.8 1.2
[159]
SNU475 STAT5A
Mean 2.42
Standard deviation 0.13
Values 2.5 2.3
[160]
THLE STAT5A
Mean 4.58
Standard deviation 0.3
Values 4.8 4.4
[161]
liver STAT5A
Mean 3.96
Standard deviation 1.5
Values 3 3.5 3.3 6.2
[162]
ref_hepatocyte SOCS1
Mean 2.1
Standard deviation 1.9
Values 1.1 0 1.3 4.7 3.4
[163]
HepG2 SOCS1
Mean 1.7
Standard deviation 0.19
Values 1.8 1.6
[164]
HepG2.C3A SOCS1
Mean 2.76
Standard deviation 1.3
Values 3.7 1.9
[165]
HuH.7 SOCS1
Mean 3.19
Standard deviation 2.1
Values 3.3 1 5.3
[166]
SNU475 SOCS1
Mean 1.11
Standard deviation 0.23
Values 1.3 0.95
[167]
THLE SOCS1
Mean 0.479
Standard deviation 0.076
Values 0.53 0.43
[168]
liver SOCS1
Mean 1.08
Standard deviation 0.8
Values 1.1 0.27 0.8 2.2
[169]
ref_hepatocyte FYN
Mean 2.1
Standard deviation 2.2
Values 2.2 0.039 0.23 2.6 5.5
[170]
HepG2 FYN
Mean 8.91
Standard deviation 0.7
Values 9.4 8.4
[171]
HepG2.C3A FYN
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[172]
HuH.7 FYN
Mean 7.43
Standard deviation 2.2
Values 8.9 4.8 8.5
[173]
SNU475 FYN
Mean 10.7
Standard deviation 2.5
Values 12 8.9
[174]
THLE FYN
Mean 34.5
Standard deviation 4.9
Values 38 31
[175]
liver FYN
Mean 5.84
Standard deviation 2.1
Values 8.9 4.4 5.1 5
[176]
ref_hepatocyte PTPRU
Mean 1.91
Standard deviation 0.89
Values 2.4 1 3.2 1.7 1.3
[177]
HepG2 PTPRU
Mean 76.4
Standard deviation 37
Values 1e+02 50
[178]
HepG2.C3A PTPRU
Mean 16
Standard deviation 1.8
Values 17 15
[179]
HuH.7 PTPRU
Mean 14.1
Standard deviation 2.2
Values 17 13 13
[180]
SNU475 PTPRU
Mean 1.18
Standard deviation 0.38
Values 0.91 1.4
[181]
THLE PTPRU
Mean 7.08
Standard deviation 3.3
Values 9.4 4.8
[182]
liver PTPRU
Mean 8.38
Standard deviation 4.8
Values 4.3 8 6 15
[183]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 2.6 2.3 1.2 0.94
[184]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 2.1 4.3
[185]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 8 9.6
[186]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 10 12 7
[187]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 8.1 6.8
[188]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[189]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 6.1 15 6 13
[190]
ref_hepatocyte GRB7
Mean 1.79
Standard deviation 1
Values 1.9 0.17 2.4 1.8 2.8
[191]
HepG2 GRB7
Mean 21
Standard deviation 1.2
Values 20 22
[192]
HepG2.C3A GRB7
Mean 23.3
Standard deviation 14
Values 34 13
[193]
HuH.7 GRB7
Mean 3.15
Standard deviation 1.7
Values 3.5 1.4 4.6
[194]
SNU475 GRB7
Mean 0.525
Standard deviation 0.097
Values 0.59 0.46
[195]
THLE GRB7
Mean 0.975
Standard deviation 0.065
Values 0.93 1
[196]
liver GRB7
Mean 2.04
Standard deviation 1.6
Values 4 0.68 2.5 0.89
[197]
ref_hepatocyte GAB2
Mean 1.62
Standard deviation 1.7
Values 1.2 1.9 4.5 0.25 0.31
[198]
HepG2 GAB2
Mean 10.6
Standard deviation 4.9
Values 14 7.1
[199]
HepG2.C3A GAB2
Mean 8.12
Standard deviation 3.2
Values 10 5.9
[200]
HuH.7 GAB2
Mean 9.24
Standard deviation 2.5
Values 9.6 12 6.6
[201]
SNU475 GAB2
Mean 5.63
Standard deviation 0.73
Values 6.1 5.1
[202]
THLE GAB2
Mean 6.7
Standard deviation 0.57
Values 7.1 6.3
[203]
liver GAB2
Mean 3.35
Standard deviation 1.3
Values 2.8 4.2 1.8 4.6
[204]
ref_hepatocyte FER
Mean 1.25
Standard deviation 0.84
Values 1.6 1.9 2.1 0.53 0.19
[205]
HepG2 FER
Mean 2.24
Standard deviation 0.78
Values 1.7 2.8
[206]
HepG2.C3A FER
Mean 2.95
Standard deviation 1.8
Values 1.7 4.2
[207]
HuH.7 FER
Mean 1.4
Standard deviation 0.63
Values 1.6 1.9 0.68
[208]
SNU475 FER
Mean 3.24
Standard deviation 0.32
Values 3.5 3
[209]
THLE FER
Mean 3.73
Standard deviation 0.36
Values 3.5 4
[210]
liver FER
Mean 4.75
Standard deviation 2.1
Values 3.2 7.1 2.7 6
[211]
ref_hepatocyte MMP9
Mean 0.779
Standard deviation 1.6
Values 0.1 0.049 3.7 0.06 0.033
[212]
HepG2 MMP9
Mean 0.261
Standard deviation 0.18
Values 0.39 0.13
[213]
HepG2.C3A MMP9
Mean 0.112
Standard deviation 0.0078
Values 0.11 0.12
[214]
HuH.7 MMP9
Mean 0.0205
Standard deviation 0.012
Values 0.033 0.019 0.0094
[215]
SNU475 MMP9
Mean 0.53
Standard deviation 0.7
Values 0.037 1
[216]
THLE MMP9
Mean 0.101
Standard deviation 0.076
Values 0.047 0.15
[217]
liver MMP9
Mean 1
Standard deviation 0.93
Values 0.33 0.73 0.59 2.4
[218]
ref_hepatocyte JAK2
Mean 0.762
Standard deviation 0.48
Values 1.3 1.3 0.62 0.18 0.5
[219]
HepG2 JAK2
Mean 1.97
Standard deviation 1.3
Values 1 2.9
[220]
HepG2.C3A JAK2
Mean 1.75
Standard deviation 0.67
Values 1.3 2.2
[221]
HuH.7 JAK2
Mean 1.23
Standard deviation 0.34
Values 1.2 1.6 0.9
[222]
SNU475 JAK2
Mean 2.37
Standard deviation 0.1
Values 2.3 2.4
[223]
THLE JAK2
Mean 4.02
Standard deviation 0.77
Values 4.6 3.5
[224]
liver JAK2
Mean 7.06
Standard deviation 3.8
Values 4.7 11 2.9 9.8
[225]
ref_hepatocyte TEC
Mean 0.721
Standard deviation 0.42
Values 0 1.1 0.86 0.85 0.8
[226]
HepG2 TEC
Mean 0.358
Standard deviation 0.094
Values 0.42 0.29
[227]
HepG2.C3A TEC
Mean 0.242
Standard deviation 0.067
Values 0.19 0.29
[228]
HuH.7 TEC
Mean 0.35
Standard deviation 0.086
Values 0.34 0.44 0.27
[229]
SNU475 TEC
Mean 3.35
Standard deviation 0.15
Values 3.5 3.2
[230]
THLE TEC
Mean 1.26
Standard deviation 0.036
Values 1.2 1.3
[231]
liver TEC
Mean 3.09
Standard deviation 0.67
Values 2.6 4 2.6 3.2
[232]
ref_hepatocyte CBL
Mean 0.522
Standard deviation 0.26
Values 0.83 0.62 0.65 0.18 0.33
[233]
HepG2 CBL
Mean 25.2
Standard deviation 0.64
Values 26 25
[234]
HepG2.C3A CBL
Mean 10.8
Standard deviation 0.61
Values 11 10
[235]
HuH.7 CBL
Mean 12.1
Standard deviation 3
Values 15 11 9.5
[236]
SNU475 CBL
Mean 33.7
Standard deviation 5.1
Values 30 37
[237]
THLE CBL
Mean 26.4
Standard deviation 3.4
Values 24 29
[238]
liver CBL
Mean 10
Standard deviation 4.2
Values 5.8 14 7.1 14
[239]
ref_hepatocyte VAV1
Mean 0.469
Standard deviation 0.4
Values 0 0.2 0.63 0.48 1
[240]
HepG2 VAV1
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[241]
HepG2.C3A VAV1
Mean 0.0726
Standard deviation 0.034
Values 0.049 0.097
[242]
HuH.7 VAV1
Mean 0.0213
Standard deviation 0.0061
Values 0.016 0.019 0.028
[243]
SNU475 VAV1
Mean 0.0127
Standard deviation 0.018
Values 0 0.025
[244]
THLE VAV1
Mean 0.00592
Standard deviation 0.0084
Values 0.012 0
[245]
liver VAV1
Mean 1.51
Standard deviation 0.9
Values 0.75 1.8 0.82 2.6
[246]
ref_hepatocyte PIK3R3
Mean 0.405
Standard deviation 0.3
Values 0.52 0.81 0.47 0.078 0.15
[247]
HepG2 PIK3R3
Mean 2.95
Standard deviation 2.5
Values 1.2 4.7
[248]
HepG2.C3A PIK3R3
Mean 2.65
Standard deviation 1.6
Values 1.5 3.8
[249]
HuH.7 PIK3R3
Mean 4.56
Standard deviation 1.3
Values 5.7 3.1 5
[250]
SNU475 PIK3R3
Mean 6.68
Standard deviation 0.22
Values 6.5 6.8
[251]
THLE PIK3R3
Mean 3.8
Standard deviation 0.9
Values 3.2 4.4
[252]
liver PIK3R3
Mean 3.68
Standard deviation 0.27
Values 3.7 3.8 3.3 4
[253]
ref_hepatocyte GRAP
Mean 0.339
Standard deviation 0.47
Values 0 0 0 0.91 0.79
[254]
HepG2 GRAP
Mean 10.5
Standard deviation 4.7
Values 14 7.2
[255]
HepG2.C3A GRAP
Mean 1.26
Standard deviation 0.59
Values 0.85 1.7
[256]
HuH.7 GRAP
Mean 0.0316
Standard deviation 0.017
Values 0.025 0.051 0.019
[257]
SNU475 GRAP
Mean 0.0755
Standard deviation 0.015
Values 0.065 0.086
[258]
THLE GRAP
Mean 0.197
Standard deviation 0.023
Values 0.21 0.18
[259]
liver GRAP
Mean 1.71
Standard deviation 0.43
Values 1.1 2.1 1.6 2
[260]
ref_hepatocyte LCK
Mean 0.319
Standard deviation 0.43
Values 0.11 0 0.49 0 0.99
[261]
HepG2 LCK
Mean 4.84
Standard deviation 4.4
Values 8 1.7
[262]
HepG2.C3A LCK
Mean 4.55
Standard deviation 0.16
Values 4.4 4.7
[263]
HuH.7 LCK
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[264]
SNU475 LCK
Mean 0.0173
Standard deviation 0.011
Values 0.0093 0.025
[265]
THLE LCK
Mean 0.0169
Standard deviation 0.0013
Values 0.018 0.016
[266]
liver LCK
Mean 1.07
Standard deviation 0.51
Values 1.2 0.49 1.7 0.91
[267]
ref_hepatocyte CMA1
Mean 0.269
Standard deviation 0.51
Values 0 0 0 0.18 1.2
[268]
HepG2 CMA1
Mean 0.0207
Standard deviation 0.013
Values 0.011 0.03
[269]
HepG2.C3A CMA1
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[270]
HuH.7 CMA1
Mean 0
Standard deviation 0
Values 0 0 0
[271]
SNU475 CMA1
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[272]
THLE CMA1
Mean 0
Standard deviation 0
Values 0 0
[273]
liver CMA1
Mean 0.0741
Standard deviation 0.051
Values 0 0.11 0.1 0.079
[274]
ref_hepatocyte SH2B2
Mean 0.26
Standard deviation 0.25
Values 0 0.06 0.39 0.6 0.25
[275]
HepG2 SH2B2
Mean 0.577
Standard deviation 0.29
Values 0.79 0.37
[276]
HepG2.C3A SH2B2
Mean 0.326
Standard deviation 0.14
Values 0.43 0.23
[277]
HuH.7 SH2B2
Mean 0.55
Standard deviation 0.077
Values 0.6 0.46 0.59
[278]
SNU475 SH2B2
Mean 0.694
Standard deviation 0.34
Values 0.45 0.94
[279]
THLE SH2B2
Mean 0.48
Standard deviation 0.024
Values 0.5 0.46
[280]
liver SH2B2
Mean 0.171
Standard deviation 0.17
Values 0.024 0.34 0.026 0.29
[281]
ref_hepatocyte KITLG
Mean 0.0988
Standard deviation 0.16
Values 0.024 0.39 0 0.052 0.033
[282]
HepG2 KITLG
Mean 9.5
Standard deviation 3.6
Values 6.9 12
[283]
HepG2.C3A KITLG
Mean 0.616
Standard deviation 0.27
Values 0.43 0.8
[284]
HuH.7 KITLG
Mean 31.3
Standard deviation 8.5
Values 41 24 29
[285]
SNU475 KITLG
Mean 19.3
Standard deviation 0.86
Values 20 19
[286]
THLE KITLG
Mean 6.16
Standard deviation 2
Values 7.6 4.7
[287]
liver KITLG
Mean 1.15
Standard deviation 0.074
Values 1.2 1.2 1.1 1.1
[288]
ref_hepatocyte KIT
Mean 0.0798
Standard deviation 0.075
Values 0 0 0.15 0.1 0.15
[289]
HepG2 KIT
Mean 0.0222
Standard deviation 0.025
Values 0.04 0.0043
[290]
HepG2.C3A KIT
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[291]
HuH.7 KIT
Mean 0
Standard deviation 0
Values 0 0 0
[292]
SNU475 KIT
Mean 0.83
Standard deviation 0.64
Values 1.3 0.38
[293]
THLE KIT
Mean 0.0201
Standard deviation 0.013
Values 0.03 0.011
[294]
liver KIT
Mean 1.41
Standard deviation 1.3
Values 0.21 3 1.9 0.54
[295]
ref_hepatocyte GRAP2
Mean 0.0747
Standard deviation 0.12
Values 0 0 0 0.28 0.098
[296]
HepG2 GRAP2
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[297]
HepG2.C3A GRAP2
Mean 0
Standard deviation 0
Values 0 0
[298]
HuH.7 GRAP2
Mean 0.03
Standard deviation 0.03
Values 0.016 0.064 0.0094
[299]
SNU475 GRAP2
Mean 0.0348
Standard deviation 0.03
Values 0.014 0.056
[300]
THLE GRAP2
Mean 0.0801
Standard deviation 0.03
Values 0.059 0.1
[301]
liver GRAP2
Mean 0.19
Standard deviation 0.033
Values 0.14 0.2 0.21 0.21