REACTOME_BASIGIN_INTERACTIONS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PPIA Peptidyl-prolyl cis-trans isomerase A [1] -0.75[2] -0.42[3] -0.08[4] -0.75[5] -0.76[6] 0.10[7]
2 ITGB1 Integrin beta-1 [8] -0.41[9] -0.20[10] -0.06[11] 0.94[12] 0.90[13] 0.64[14]
3 BSG Basigin [15] 0.13[16] 0.27[17] 0.42[18] -0.63[19] -0.16[20] -0.55[21]
4 SLC3A2 4F2 cell-surface antigen heavy chain [22] -0.70[23] -1.60[24] -1.46[25] -1.37[26] -0.92[27] -1.57[28]
5 ATP1B1 Sodium/potassium-transporting ATPase subunit beta-1 [29] -0.96[30] -0.34[31] -0.32[32] -1.19[33] -2.60[34] -0.29[35]
6 CAV1 Caveolin-1 [36] -7.48[37] -10.11[38] -3.84[39] 0.85[40] -0.62[41] -1.51[42]
7 SLC7A5 Large neutral amino acids transporter small subunit 1 [43] 2.24[44] 1.20[45] 0.10[46] -0.65[47] 0.01[48] -1.29[49]
8 SLC16A1 Monocarboxylate transporter 1 [50] 0.32[51] 1.34[52] 1.58[53] 0.14[54] 0.72[55] 1.66[56]
9 ITGA6 Integrin alpha-6 [57] -0.30[58] 0.28[59] 0.38[60] -1.67[61] -3.42[62] -0.05[63]
10 ATP1B3 Sodium/potassium-transporting ATPase subunit beta-3 [64] 0.32[65] -0.22[66] -0.05[67] 0.28[68] 0.85[69] -1.53[70]
11 SLC16A3 Monocarboxylate transporter 4 [71] 3.31[72] 3.11[73] 1.58[74] 0.87[75] 2.09[76] -2.68[77]
12 MMP1 Interstitial collagenase [78] -5.81[79] -9.39[80] [81] -2.27[82] -2.85[83] -11.65[84]
13 SLC7A9 b(0,+)-type amino acid transporter 1 [85] -3.38[86] -1.75[87] -3.76[88] -8.85[89] -8.42[90] 0.11[91]
14 PPIL2 Peptidyl-prolyl cis-trans isomerase-like 2 [92] 0.87[93] 0.86[94] 0.91[95] 0.36[96] -0.15[97] 1.29[98]
15 ITGA3 Integrin alpha-3 [99] 1.31[100] -3.21[101] -4.18[102] 3.86[103] 3.43[104] -1.00[105]
16 SLC7A6 Y+L amino acid transporter 2 [106] 2.56[107] 2.33[108] 1.73[109] 1.95[110] 2.05[111] 0.97[112]
17 SLC7A7 Y+L amino acid transporter 1 [113] 0.62[114] -2.32[115] 2.50[116] -0.69[117] 0.24[118] 1.49[119]
18 SLC7A11 Cystine/glutamate transporter [120] 2.03[121] 3.07[122] 2.92[123] 4.36[124] 3.04[125] -0.54[126]
19 SLC7A8 Large neutral amino acids transporter small subunit 2 [127] -3.95[128] -5.90[129] -1.09[130] 0.09[131] 2.26[132] 2.64[133]
20 SPN Leukosialin [134] 1.39[135] -0.29[136] -1.10[137] -1.89[138] -2.18[139] 0.58[140]
21 ATP1B2 Sodium/potassium-transporting ATPase subunit beta-2 [141] -2.98[142] -2.06[143] -0.84[144] -1.20[145] -2.17[146] 2.29[147]
22 L1CAM Neural cell adhesion molecule L1 [148] 5.21[149] 3.60[150] -4.19[151] 5.29[152] -0.71[153] -0.19[154]
23 MAG Myelin-associated glycoprotein [155] 1.82[156] -0.70[157] [158] -1.88[159] -1.02[160] -2.80[161]
24 SLC16A8 Monocarboxylate transporter 3 [162] -1.04[163] 3.78[164] 1.40[165] 1.00[166] 0.32[167] 4.21[168]
25 SLC7A10 Asc-type amino acid transporter 1 [169] [170] [171] [172] [173] [174] [175]
[1]
ref_hepatocyte PPIA
Mean 240
Standard deviation 74
Values 1.4e+02 2.9e+02 1.9e+02 3.2e+02 2.5e+02
[2]
HepG2 PPIA
Mean 492
Standard deviation 1e+02
Values 4.2e+02 5.6e+02
[3]
HepG2.C3A PPIA
Mean 483
Standard deviation 1.5e+02
Values 3.8e+02 5.9e+02
[4]
HuH.7 PPIA
Mean 582
Standard deviation 2.2e+02
Values 5.6e+02 3.8e+02 8.1e+02
[5]
SNU475 PPIA
Mean 374
Standard deviation 68
Values 4.2e+02 3.3e+02
[6]
THLE PPIA
Mean 455
Standard deviation 72
Values 4e+02 5.1e+02
[7]
liver PPIA
Mean 261
Standard deviation 2.1e+02
Values 4.6e+02 87 4.3e+02 66
[8]
ref_hepatocyte ITGB1
Mean 128
Standard deviation 1e+02
Values 91 3e+02 1.4e+02 58 51
[9]
HepG2 ITGB1
Mean 333
Standard deviation 10
Values 3.4e+02 3.3e+02
[10]
HepG2.C3A ITGB1
Mean 301
Standard deviation 47
Values 2.7e+02 3.3e+02
[11]
HuH.7 ITGB1
Mean 317
Standard deviation 16
Values 3.3e+02 3.3e+02 3e+02
[12]
SNU475 ITGB1
Mean 648
Standard deviation 88
Values 7.1e+02 5.9e+02
[13]
THLE ITGB1
Mean 768
Standard deviation 1.5e+02
Values 6.6e+02 8.8e+02
[14]
liver ITGB1
Mean 204
Standard deviation 85
Values 1.2e+02 3.2e+02 2.1e+02 1.6e+02
[15]
ref_hepatocyte BSG
Mean 85.8
Standard deviation 48
Values 64 71 1.7e+02 74 50
[16]
HepG2 BSG
Mean 323
Standard deviation 1.3e+02
Values 4.1e+02 2.3e+02
[17]
HepG2.C3A BSG
Mean 278
Standard deviation 1e+02
Values 3.5e+02 2.1e+02
[18]
HuH.7 BSG
Mean 295
Standard deviation 58
Values 3.4e+02 2.3e+02 3.2e+02
[19]
SNU475 BSG
Mean 146
Standard deviation 4
Values 1.5e+02 1.4e+02
[20]
THLE BSG
Mean 246
Standard deviation 32
Values 2.2e+02 2.7e+02
[21]
liver BSG
Mean 59.6
Standard deviation 44
Values 1.1e+02 25 87 20
[22]
ref_hepatocyte SLC3A2
Mean 72.1
Standard deviation 43
Values 56 49 1.3e+02 1e+02 22
[23]
HepG2 SLC3A2
Mean 153
Standard deviation 40
Values 1.8e+02 1.2e+02
[24]
HepG2.C3A SLC3A2
Mean 64.2
Standard deviation 13
Values 74 55
[25]
HuH.7 SLC3A2
Mean 67.5
Standard deviation 3
Values 64 68 70
[26]
SNU475 SLC3A2
Mean 73.5
Standard deviation 36
Values 48 99
[27]
THLE SLC3A2
Mean 122
Standard deviation 3.4
Values 1.2e+02 1.2e+02
[28]
liver SLC3A2
Mean 24.7
Standard deviation 11
Values 28 16 39 16
[29]
ref_hepatocyte ATP1B1
Mean 43.8
Standard deviation 19
Values 61 66 29 23 39
[30]
HepG2 ATP1B1
Mean 77.7
Standard deviation 7.7
Values 72 83
[31]
HepG2.C3A ATP1B1
Mean 93.2
Standard deviation 15
Values 1e+02 83
[32]
HuH.7 ATP1B1
Mean 90.4
Standard deviation 15
Values 81 1.1e+02 82
[33]
SNU475 ATP1B1
Mean 50.5
Standard deviation 8.1
Values 56 45
[34]
THLE ATP1B1
Mean 23.2
Standard deviation 4.8
Values 20 27
[35]
liver ATP1B1
Mean 36.5
Standard deviation 10
Values 44 41 39 22
[36]
ref_hepatocyte CAV1
Mean 22.6
Standard deviation 36
Values 0 84 28 0.35 0.99
[37]
HepG2 CAV1
Mean 0.438
Standard deviation 0.44
Values 0.75 0.12
[38]
HepG2.C3A CAV1
Mean 0.055
Standard deviation 0.032
Values 0.078 0.032
[39]
HuH.7 CAV1
Mean 4.08
Standard deviation 1.9
Values 3.5 6.2 2.5
[40]
SNU475 CAV1
Mean 108
Standard deviation 15
Values 1.2e+02 98
[41]
THLE CAV1
Mean 47.4
Standard deviation 15
Values 37 58
[42]
liver CAV1
Mean 8.05
Standard deviation 2.9
Values 7.6 8.2 12 4.7
[43]
ref_hepatocyte SLC7A5
Mean 20.3
Standard deviation 37
Values 86 1.6 8.1 3.7 1.8
[44]
HepG2 SLC7A5
Mean 330
Standard deviation 84
Values 3.9e+02 2.7e+02
[45]
HepG2.C3A SLC7A5
Mean 125
Standard deviation 38
Values 1.5e+02 98
[46]
HuH.7 SLC7A5
Mean 56.1
Standard deviation 23
Values 76 31 61
[47]
SNU475 SLC7A5
Mean 34.2
Standard deviation 11
Values 42 26
[48]
THLE SLC7A5
Mean 65.6
Standard deviation 9.3
Values 72 59
[49]
liver SLC7A5
Mean 8.45
Standard deviation 2.5
Values 8.8 5.7 12 7.6
[50]
ref_hepatocyte SLC16A1
Mean 16.1
Standard deviation 7.8
Values 29 18 13 11 9.6
[51]
HepG2 SLC16A1
Mean 69
Standard deviation 5.5
Values 65 73
[52]
HepG2.C3A SLC16A1
Mean 110
Standard deviation 10
Values 1e+02 1.2e+02
[53]
HuH.7 SLC16A1
Mean 124
Standard deviation 14
Values 1.4e+02 1.1e+02 1.2e+02
[54]
SNU475 SLC16A1
Mean 46.7
Standard deviation 1.1
Values 46 48
[55]
THLE SLC16A1
Mean 84.9
Standard deviation 5.8
Values 81 89
[56]
liver SLC16A1
Mean 51.7
Standard deviation 8.4
Values 58 51 40 58
[57]
ref_hepatocyte ITGA6
Mean 15.5
Standard deviation 18
Values 42 24 7.3 1.6 2.3
[58]
HepG2 ITGA6
Mean 43.6
Standard deviation 3.8
Values 41 46
[59]
HepG2.C3A ITGA6
Mean 51
Standard deviation 3.8
Values 48 54
[60]
HuH.7 ITGA6
Mean 51.9
Standard deviation 8.3
Values 61 46 49
[61]
SNU475 ITGA6
Mean 12.9
Standard deviation 0.61
Values 13 12
[62]
THLE ITGA6
Mean 4.67
Standard deviation 1.5
Values 3.6 5.7
[63]
liver ITGA6
Mean 15.3
Standard deviation 3.9
Values 16 20 12 13
[64]
ref_hepatocyte ATP1B3
Mean 13.6
Standard deviation 14
Values 35 20 7.2 3.4 2.2
[65]
HepG2 ATP1B3
Mean 58.1
Standard deviation 2.3
Values 60 56
[66]
HepG2.C3A ATP1B3
Mean 31.3
Standard deviation 11
Values 24 39
[67]
HuH.7 ATP1B3
Mean 33.6
Standard deviation 11
Values 36 22 43
[68]
SNU475 ATP1B3
Mean 43.5
Standard deviation 9.4
Values 37 50
[69]
THLE ATP1B3
Mean 78.4
Standard deviation 10
Values 71 86
[70]
liver ATP1B3
Mean 4.76
Standard deviation 3.8
Values 9 1.5 7 1.5
[71]
ref_hepatocyte SLC16A3
Mean 10.6
Standard deviation 21
Values 49 2.1 0.6 1.3 0.59
[72]
HepG2 SLC16A3
Mean 364
Standard deviation 94
Values 4.3e+02 3e+02
[73]
HepG2.C3A SLC16A3
Mean 248
Standard deviation 28
Values 2.7e+02 2.3e+02
[74]
HuH.7 SLC16A3
Mean 82.1
Standard deviation 4.7
Values 87 81 78
[75]
SNU475 SLC16A3
Mean 51.2
Standard deviation 0.12
Values 51 51
[76]
THLE SLC16A3
Mean 145
Standard deviation 23
Values 1.3e+02 1.6e+02
[77]
liver SLC16A3
Mean 1.69
Standard deviation 0.84
Values 0.85 1.1 2.6 2.2
[78]
ref_hepatocyte MMP1
Mean 10.4
Standard deviation 23
Values 0 0.4 52 0.078 0.12
[79]
HepG2 MMP1
Mean 0.642
Standard deviation 0.089
Values 0.7 0.58
[80]
HepG2.C3A MMP1
Mean 0.0419
Standard deviation 0.032
Values 0.019 0.064
[81]
HuH.7 MMP1
Mean 0
Standard deviation 0
Values 0 0 0
[82]
SNU475 MMP1
Mean 5.69
Standard deviation 7.7
Values 0.27 11
[83]
THLE MMP1
Mean 4.66
Standard deviation 3.3
Values 2.4 7
[84]
liver MMP1
Mean 0.00331
Standard deviation 0.0066
Values 0 0 0 0.013
[85]
ref_hepatocyte SLC7A9
Mean 4.79
Standard deviation 3.3
Values 1.5 7.5 1.1 6.1 7.8
[86]
HepG2 SLC7A9
Mean 1.59
Standard deviation 0.08
Values 1.6 1.5
[87]
HepG2.C3A SLC7A9
Mean 3.84
Standard deviation 0.15
Values 3.9 3.7
[88]
HuH.7 SLC7A9
Mean 0.909
Standard deviation 0.083
Values 0.82 0.92 0.98
[89]
SNU475 SLC7A9
Mean 0.0274
Standard deviation 0.026
Values 0.0093 0.046
[90]
THLE SLC7A9
Mean 0.0449
Standard deviation 0.0034
Values 0.047 0.043
[91]
liver SLC7A9
Mean 5.26
Standard deviation 1.2
Values 6.4 3.8 5.9 5
[92]
ref_hepatocyte PPIL2
Mean 4.11
Standard deviation 1.8
Values 2.6 1.7 4.9 5.6 5.7
[93]
HepG2 PPIL2
Mean 25.8
Standard deviation 1.4
Values 25 27
[94]
HepG2.C3A PPIL2
Mean 20
Standard deviation 1.3
Values 21 19
[95]
HuH.7 PPIL2
Mean 19.9
Standard deviation 5.1
Values 21 14 24
[96]
SNU475 PPIL2
Mean 13.9
Standard deviation 1.7
Values 15 13
[97]
THLE PPIL2
Mean 11.9
Standard deviation 3.6
Values 9.3 14
[98]
liver PPIL2
Mean 10.2
Standard deviation 1.1
Values 11 9.2 11 9.5
[99]
ref_hepatocyte ITGA3
Mean 3.01
Standard deviation 6.1
Values 0 14 0.81 0.21 0.13
[100]
HepG2 ITGA3
Mean 25.8
Standard deviation 7.7
Values 31 20
[101]
HepG2.C3A ITGA3
Mean 0.878
Standard deviation 0.34
Values 0.64 1.1
[102]
HuH.7 ITGA3
Mean 0.428
Standard deviation 0.18
Values 0.61 0.24 0.44
[103]
SNU475 ITGA3
Mean 116
Standard deviation 18
Values 1e+02 1.3e+02
[104]
THLE ITGA3
Mean 104
Standard deviation 35
Values 80 1.3e+02
[105]
liver ITGA3
Mean 1.53
Standard deviation 0.68
Values 0.94 1.9 0.98 2.3
[106]
ref_hepatocyte SLC7A6
Mean 2.26
Standard deviation 1.6
Values 3.1 2.8 4.2 0.79 0.5
[107]
HepG2 SLC7A6
Mean 45.9
Standard deviation 8.7
Values 40 52
[108]
HepG2.C3A SLC7A6
Mean 30.5
Standard deviation 1.2
Values 30 31
[109]
HuH.7 SLC7A6
Mean 19.2
Standard deviation 3.5
Values 22 15 20
[110]
SNU475 SLC7A6
Mean 23
Standard deviation 1.8
Values 24 22
[111]
THLE SLC7A6
Mean 30
Standard deviation 0.62
Values 30 30
[112]
liver SLC7A6
Mean 4.49
Standard deviation 1.1
Values 3.1 5 4.2 5.7
[113]
ref_hepatocyte SLC7A7
Mean 1.18
Standard deviation 0.53
Values 0.81 0.49 1.4 1.8 1.3
[114]
HepG2 SLC7A7
Mean 6.24
Standard deviation 2.6
Values 8.1 4.4
[115]
HepG2.C3A SLC7A7
Mean 0.638
Standard deviation 0.13
Values 0.73 0.55
[116]
HuH.7 SLC7A7
Mean 17.2
Standard deviation 2.7
Values 20 14 17
[117]
SNU475 SLC7A7
Mean 1.94
Standard deviation 0.26
Values 1.8 2.1
[118]
THLE SLC7A7
Mean 4.5
Standard deviation 1.6
Values 3.3 5.7
[119]
liver SLC7A7
Mean 3.37
Standard deviation 0.57
Values 2.5 3.5 3.6 3.9
[120]
ref_hepatocyte SLC7A11
Mean 1.16
Standard deviation 1.5
Values 0.84 3.6 1.1 0.13 0.081
[121]
HepG2 SLC7A11
Mean 16.2
Standard deviation 8
Values 22 11
[122]
HepG2.C3A SLC7A11
Mean 26.1
Standard deviation 9.4
Values 33 19
[123]
HuH.7 SLC7A11
Mean 22.5
Standard deviation 3.7
Values 25 24 18
[124]
SNU475 SLC7A11
Mean 62.6
Standard deviation 14
Values 53 72
[125]
THLE SLC7A11
Mean 30.6
Standard deviation 10
Values 38 24
[126]
liver SLC7A11
Mean 0.81
Standard deviation 0.61
Values 1.7 0.77 0.26 0.54
[127]
ref_hepatocyte SLC7A8
Mean 0.69
Standard deviation 0.69
Values 0 0 1.2 0.72 1.5
[128]
HepG2 SLC7A8
Mean 0.154
Standard deviation 0.21
Values 0.3 0.0043
[129]
HepG2.C3A SLC7A8
Mean 0.0312
Standard deviation 0.017
Values 0.019 0.043
[130]
HuH.7 SLC7A8
Mean 0.832
Standard deviation 0.6
Values 1.3 0.16 1
[131]
SNU475 SLC7A8
Mean 1.93
Standard deviation 0.094
Values 1.9 2
[132]
THLE SLC7A8
Mean 10.6
Standard deviation 0.99
Values 9.9 11
[133]
liver SLC7A8
Mean 4.38
Standard deviation 3.2
Values 2.8 2.8 9.2 2.7
[134]
ref_hepatocyte SPN
Mean 0.617
Standard deviation 0.27
Values 0.86 0.51 0.23 0.59 0.89
[135]
HepG2 SPN
Mean 5.55
Standard deviation 5.7
Values 9.6 1.5
[136]
HepG2.C3A SPN
Mean 1.36
Standard deviation 0.31
Values 1.6 1.1
[137]
HuH.7 SPN
Mean 0.741
Standard deviation 0.11
Values 0.82 0.78 0.62
[138]
SNU475 SPN
Mean 0.438
Standard deviation 0.0036
Values 0.44 0.44
[139]
THLE SPN
Mean 0.438
Standard deviation 0.092
Values 0.5 0.37
[140]
liver SPN
Mean 0.939
Standard deviation 0.072
Values 0.89 0.96 0.87 1
[141]
ref_hepatocyte ATP1B2
Mean 0.326
Standard deviation 0.32
Values 0.84 0.42 0.19 0.14 0.033
[142]
HepG2 ATP1B2
Mean 0.142
Standard deviation 0.043
Values 0.17 0.11
[143]
HepG2.C3A ATP1B2
Mean 0.211
Standard deviation 0.1
Values 0.28 0.14
[144]
HuH.7 ATP1B2
Mean 0.469
Standard deviation 0.13
Values 0.37 0.62 0.42
[145]
SNU475 ATP1B2
Mean 0.373
Standard deviation 0.068
Values 0.32 0.42
[146]
THLE ATP1B2
Mean 0.232
Standard deviation 0.065
Values 0.28 0.19
[147]
liver ATP1B2
Mean 1.62
Standard deviation 2.2
Values 5 0.23 0.9 0.4
[148]
ref_hepatocyte L1CAM
Mean 0.225
Standard deviation 0.42
Values 0.96 0 0.16 0 0
[149]
HepG2 L1CAM
Mean 28.6
Standard deviation 14
Values 38 19
[150]
HepG2.C3A L1CAM
Mean 7.31
Standard deviation 4.5
Values 11 4.1
[151]
HuH.7 L1CAM
Mean 0.0318
Standard deviation 0.019
Values 0.041 0.045 0.0094
[152]
SNU475 L1CAM
Mean 23.1
Standard deviation 10
Values 30 16
[153]
THLE L1CAM
Mean 0.442
Standard deviation 0.053
Values 0.48 0.4
[154]
liver L1CAM
Mean 0.2
Standard deviation 0.1
Values 0.12 0.16 0.18 0.34
[155]
ref_hepatocyte MAG
Mean 0.0472
Standard deviation 0.11
Values 0 0 0 0 0.24
[156]
HepG2 MAG
Mean 0.571
Standard deviation 0.55
Values 0.96 0.18
[157]
HepG2.C3A MAG
Mean 0.0779
Standard deviation 0.041
Values 0.049 0.11
[158]
HuH.7 MAG
Mean 0
Standard deviation 0
Values 0 0 0
[159]
SNU475 MAG
Mean 0.0338
Standard deviation 0.0047
Values 0.037 0.03
[160]
THLE MAG
Mean 0.0745
Standard deviation 0.03
Values 0.053 0.096
[161]
liver MAG
Mean 0.00688
Standard deviation 0.008
Values 0 0.014 0 0.013
[162]
ref_hepatocyte SLC16A8
Mean 0.00813
Standard deviation 0.018
Values 0 0 0 0 0.041
[163]
HepG2 SLC16A8
Mean 0.0136
Standard deviation 0.013
Values 0.023 0.0043
[164]
HepG2.C3A SLC16A8
Mean 0.301
Standard deviation 0.14
Values 0.4 0.2
[165]
HuH.7 SLC16A8
Mean 0.0551
Standard deviation 0.08
Values 0.0082 0.15 0.0094
[166]
SNU475 SLC16A8
Mean 0.0428
Standard deviation 0.025
Values 0.06 0.025
[167]
THLE SLC16A8
Mean 0.0325
Standard deviation 0.046
Values 0.065 0
[168]
liver SLC16A8
Mean 0.153
Standard deviation 0.17
Values 0.024 0.26 0 0.33
[169]
ref_hepatocyte SLC7A10
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[170]
HepG2 SLC7A10
Mean 0.104
Standard deviation 0.032
Values 0.13 0.082
[171]
HepG2.C3A SLC7A10
Mean 0.217
Standard deviation 0.064
Values 0.26 0.17
[172]
HuH.7 SLC7A10
Mean 9.27
Standard deviation 1.1
Values 8.9 8.4 11
[173]
SNU475 SLC7A10
Mean 0.476
Standard deviation 0.26
Values 0.66 0.29
[174]
THLE SLC7A10
Mean 0.0497
Standard deviation 0.055
Values 0.089 0.011
[175]
liver SLC7A10
Mean 0.0165
Standard deviation 0.033
Values 0 0 0 0.066