REACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ADAM10 Disintegrin and metalloproteinase domain-containing protein 10 [1] -1.54[2] -0.32[3] -0.12[4] -0.39[5] 0.28[6] -0.56[7]
2 ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 [8] -1.85[9] -1.22[10] -1.32[11] 0.07[12] -0.53[13] -1.28[14]
3 JAG1 Protein jagged-1 [15] 2.25[16] 1.58[17] 1.21[18] -0.16[19] -1.25[20] -0.31[21]
4 NOTCH1 Neurogenic locus notch homolog protein 1 [22] -0.62[23] -1.04[24] 0.46[25] 0.91[26] 1.53[27] 3.28[28]
5 DLL4 Delta-like protein 4 [29] -1.78[30] -0.33[31] -1.39[32] -4.80[33] -3.25[34] 1.84[35]
6 DLL1 Delta-like protein 1 [36] -6.88[37] -4.94[38] -4.71[39] -8.46[40] -1.10[41] 1.15[42]
7 JAG2 Protein jagged-2 [43] 0.92[44] -2.28[45] 1.93[46] 4.18[47] 1.61[48] 0.54[49]
[1]
ref_hepatocyte ADAM10
Mean 8.78
Standard deviation 8.3
Values 21 13 2.8 3.4 3.4
[2]
HepG2 ADAM10
Mean 38.3
Standard deviation 10
Values 31 46
[3]
HepG2.C3A ADAM10
Mean 47.7
Standard deviation 4.9
Values 44 51
[4]
HuH.7 ADAM10
Mean 46.6
Standard deviation 9
Values 51 53 36
[5]
SNU475 ADAM10
Mean 39.1
Standard deviation 5.2
Values 43 35
[6]
THLE ADAM10
Mean 58.2
Standard deviation 3.8
Values 56 61
[7]
liver ADAM10
Mean 21.7
Standard deviation 10
Values 13 34 14 26
[8]
ref_hepatocyte ADAM17
Mean 5.04
Standard deviation 4.3
Values 10 8.5 4.3 1 1.1
[9]
HepG2 ADAM17
Mean 17.8
Standard deviation 0.96
Values 18 17
[10]
HepG2.C3A ADAM17
Mean 14.6
Standard deviation 0.94
Values 14 15
[11]
HuH.7 ADAM17
Mean 11.7
Standard deviation 1.5
Values 13 12 10
[12]
SNU475 ADAM17
Mean 31
Standard deviation 2.8
Values 33 29
[13]
THLE ADAM17
Mean 19
Standard deviation 2.3
Values 17 21
[14]
liver ADAM17
Mean 7.57
Standard deviation 0.72
Values 7.2 8.6 7 7.4
[15]
ref_hepatocyte JAG1
Mean 2.61
Standard deviation 3.4
Values 8.4 2.4 1.7 0.3 0.21
[16]
HepG2 JAG1
Mean 158
Standard deviation 86
Values 2.2e+02 97
[17]
HepG2.C3A JAG1
Mean 52.9
Standard deviation 7.2
Values 58 48
[18]
HuH.7 JAG1
Mean 35.1
Standard deviation 12
Values 45 21 39
[19]
SNU475 JAG1
Mean 13.7
Standard deviation 0.39
Values 13 14
[20]
THLE JAG1
Mean 6
Standard deviation 0.4
Values 5.7 6.3
[21]
liver JAG1
Mean 7.68
Standard deviation 5.1
Values 4.1 8.6 3.5 15
[22]
ref_hepatocyte NOTCH1
Mean 0.644
Standard deviation 0.25
Values 0.33 0.55 0.55 0.91 0.89
[23]
HepG2 NOTCH1
Mean 5.33
Standard deviation 3.7
Values 8 2.7
[24]
HepG2.C3A NOTCH1
Mean 2.12
Standard deviation 0.1
Values 2.1 2.2
[25]
HuH.7 NOTCH1
Mean 5.14
Standard deviation 1.4
Values 5.4 6.4 3.6
[26]
SNU475 NOTCH1
Mean 7.09
Standard deviation 0.64
Values 6.6 7.5
[27]
THLE NOTCH1
Mean 10.2
Standard deviation 2.2
Values 8.6 12
[28]
liver NOTCH1
Mean 22.8
Standard deviation 16
Values 10 31 8.8 41
[29]
ref_hepatocyte DLL4
Mean 0.192
Standard deviation 0.12
Values 0.27 0 0.32 0.21 0.16
[30]
HepG2 DLL4
Mean 0.711
Standard deviation 0.21
Values 0.86 0.56
[31]
HepG2.C3A DLL4
Mean 1.04
Standard deviation 0.087
Values 1.1 0.98
[32]
HuH.7 DLL4
Mean 0.424
Standard deviation 0.13
Values 0.45 0.54 0.28
[33]
SNU475 DLL4
Mean 0.0403
Standard deviation 0.05
Values 0.0046 0.076
[34]
THLE DLL4
Mean 0.111
Standard deviation 0.039
Values 0.083 0.14
[35]
liver DLL4
Mean 2.51
Standard deviation 0.68
Values 3.4 2 2 2.7
[36]
ref_hepatocyte DLL1
Mean 0.139
Standard deviation 0.16
Values 0 0 0.22 0.38 0.098
[37]
HepG2 DLL1
Mean 0.015
Standard deviation 0.021
Values 0 0.03
[38]
HepG2.C3A DLL1
Mean 0.0307
Standard deviation 0.0021
Values 0.029 0.032
[39]
HuH.7 DLL1
Mean 0.0308
Standard deviation 0.012
Values 0.016 0.039 0.037
[40]
SNU475 DLL1
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[41]
THLE DLL1
Mean 0.356
Standard deviation 0.16
Values 0.47 0.24
[42]
liver DLL1
Mean 1.13
Standard deviation 0.35
Values 1.6 1.2 0.72 1.1
[43]
ref_hepatocyte JAG2
Mean 0.109
Standard deviation 0.15
Values 0 0.38 0.043 0.086 0.041
[44]
HepG2 JAG2
Mean 2.63
Standard deviation 2.9
Values 4.7 0.56
[45]
HepG2.C3A JAG2
Mean 0.152
Standard deviation 0.18
Values 0.28 0.021
[46]
HuH.7 JAG2
Mean 2.4
Standard deviation 0.54
Values 3 1.9 2.3
[47]
SNU475 JAG2
Mean 11.6
Standard deviation 2.5
Values 13 9.8
[48]
THLE JAG2
Mean 1.82
Standard deviation 0.62
Values 2.3 1.4
[49]
liver JAG2
Mean 0.58
Standard deviation 0.49
Values 0.38 0.59 0.1 1.3