REACTOME_SIGNALING_BY_MODERATE_KINASE_ACTIVITY_BRAF_MUTANTS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 FGG Fibrinogen gamma chain [1] -4.03[2] -2.63[3] -2.52[4] -10.33[5] -12.22[6] -0.61[7]
2 FGA Fibrinogen alpha chain [8] -3.69[9] -2.87[10] -2.41[11] -9.54[12] -12.23[13] 0.06[14]
3 FGB Fibrinogen beta chain [15] -4.90[16] -3.65[17] -1.43[18] -7.67[19] -10.87[20] 0.84[21]
4 ACTB Actin, cytoplasmic 1 [22] 1.18[23] 0.93[24] 1.40[25] 1.96[26] 1.58[27] -1.23[28]
5 ACTG1 Actin, cytoplasmic 2 [29] 2.46[30] 1.57[31] 1.51[32] 1.76[33] 2.17[34] -1.98[35]
6 PEBP1 Phosphatidylethanolamine-binding protein 1 [36] 0.72[37] 1.51[38] 0.34[39] -1.84[40] -1.25[41] -0.77[42]
7 FN1 Fibronectin [43] 6.06[44] 5.96[45] 5.70[46] 5.87[47] 6.08[48] 2.25[49]
8 RAP1B Ras-related protein Rap-1b [50] 0.27[51] 1.31[52] 0.93[53] 2.43[54] 2.19[55] -1.94[56]
9 PHB Prohibitin [57] 2.65[58] 2.97[59] 2.24[60] 1.70[61] 1.72[62] -1.05[63]
10 YWHAB 14-3-3 protein beta/alpha [64] 3.61[65] 3.75[66] 2.87[67] 4.25[68] 3.69[69] -0.14[70]
11 CALM1 Calmodulin-1 [71] 2.65[72] 3.11[73] 3.42[74] 4.53[75] 3.82[76] 1.57[77]
12 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 [78] 1.64[79] 1.74[80] 2.16[81] 2.41[82] 2.92[83] -1.24[84]
13 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 [85] 2.62[86] 2.73[87] 3.44[88] 2.11[89] 2.60[90] -1.75[91]
14 RAP1A Ras-related protein Rap-1A [92] 1.52[93] 1.89[94] 2.57[95] 2.74[96] 2.50[97] -1.34[98]
15 RAF1 RAF proto-oncogene serine/threonine-protein kinase [99] 2.51[100] 3.34[101] 4.45[102] 2.77[103] 3.64[104] 1.05[105]
16 NRAS GTPase NRas [106] 3.20[107] 4.06[108] 4.32[109] 3.95[110] 3.53[111] -0.30[112]
17 ARAF Serine/threonine-protein kinase A-Raf [113] 2.11[114] 2.24[115] 2.35[116] 2.86[117] 2.90[118] 0.83[119]
18 TLN1 Talin-1 [120] 5.56[121] 4.62[122] 5.24[123] 6.06[124] 6.08[125] 3.31[126]
19 VCL Vinculin [127] 3.34[128] 3.49[129] 3.47[130] 5.78[131] 4.88[132] 0.76[133]
20 HRAS GTPase HRas [134] 1.56[135] 1.29[136] 0.34[137] 2.00[138] 1.79[139] -2.71[140]
21 APBB1IP Amyloid beta A4 precursor protein-binding family B member 1-interacting protein -5.96[141] [142] -3.76[143] -0.35[144] -3.11[145] -0.58[146]
22 MAP3K11 Mitogen-activated protein kinase kinase kinase 11 [147] 3.65[148] 4.03[149] 3.50[150] 3.10[151] 2.96[152] 0.41[153]
23 MAPK1 Mitogen-activated protein kinase 1 [154] 4.28[155] 4.85[156] 4.52[157] 4.80[158] 4.46[159] 1.73[160]
24 CSK Tyrosine-protein kinase CSK [161] 2.95[162] 2.87[163] 3.09[164] 2.94[165] 2.54[166] -0.91[167]
25 KRAS GTPase KRas [168] 2.05[169] 2.46[170] 3.91[171] 3.75[172] 3.42[173] 0.63[174]
26 MARK3 MAP/microtubule affinity-regulating kinase 3 [175] 2.49[176] 3.19[177] 3.02[178] 4.08[179] 3.78[180] 0.22[181]
27 ARRB2 Beta-arrestin-2 [182] 2.74[183] 3.55[184] 3.35[185] 1.63[186] 2.44[187] -0.92[188]
28 CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta [189] 2.70[190] 3.44[191] 4.80[192] 3.63[193] 2.83[194] 1.36[195]
29 IQGAP1 Ras GTPase-activating-like protein IQGAP1 [196] 4.42[197] 4.40[198] 4.66[199] 6.92[200] 6.77[201] 1.98[202]
30 MAPK3 Mitogen-activated protein kinase 3 [203] 4.42[204] 4.89[205] 4.78[206] 3.37[207] 3.40[208] -1.09[209]
31 SRC Proto-oncogene tyrosine-protein kinase Src [210] 5.59[211] 6.01[212] 4.85[213] 5.35[214] 4.53[215] -0.90[216]
32 BRAP BRCA1-associated protein [217] 2.92[218] 3.56[219] 3.48[220] 3.83[221] 3.95[222] 0.70[223]
33 CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 3.34[224] 4.99[225] 4.44[226] 4.63[227] 4.21[228] 0.91[229]
34 ITGB3 Integrin beta-3 [230] 0.94[231] -1.34[232] 2.02[233] 5.80[234] 5.48[235] 1.28[236]
35 BRAF Serine/threonine-protein kinase B-raf [237] 2.82[238] 2.97[239] 4.85[240] 3.69[241] 3.39[242] 1.81[243]
36 JAK2 Tyrosine-protein kinase JAK2 [244] 2.80[245] 3.22[246] 2.62[247] 3.71[248] 4.32[249] 2.66[250]
37 ARRB1 Beta-arrestin-1 [251] 6.15[252] 6.39[253] 5.53[254] 5.10[255] 4.92[256] 3.22[257]
38 CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta [258] 0.03[259] -0.86[260] -3.98[261] 0.09[262] 0.73[263] 1.10[264]
39 CNKSR1 Connector enhancer of kinase suppressor of ras 1 [265] 4.84[266] 6.74[267] 2.48[268] 1.74[269] 1.21[270] 0.34[271]
40 KSR1 Kinase suppressor of Ras 1 [272] 5.83[273] 5.96[274] 2.72[275] 5.00[276] 5.50[277] 0.68[278]
41 CNKSR2 Connector enhancer of kinase suppressor of ras 2 [279] -1.22[280] -0.83[281] 8.66[282] 6.65[283] 4.81[284] 3.08[285]
42 VWF von Willebrand factor [286] 3.54[287] 1.81[288] -0.73[289] 3.10[290] 0.53[291] 5.67[292]
43 ITGA2B Integrin alpha-IIb [293] 6.17[294] 6.89[295] 6.73[296] 5.97[297] 4.34[298] 2.57[299]
44 KSR2 Kinase suppressor of Ras 2 [300] 2.80[301] 2.22[302] [303] 1.69[304] [305] 1.27[306]
45 CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha [307] [308] [309] [310] [311] [312] [313]
[1]
ref_hepatocyte FGG
Mean 8.49e+03
Standard deviation 1.1e+04
Values 1.5e+03 1.1e+02 9e+02 2.5e+04 1.5e+04
[2]
HepG2 FGG
Mean 194
Standard deviation 1.5e+02
Values 91 3e+02
[3]
HepG2.C3A FGG
Mean 338
Standard deviation 15
Values 3.3e+02 3.5e+02
[4]
HuH.7 FGG
Mean 389
Standard deviation 3e+02
Values 2.1e+02 7.3e+02 2.3e+02
[5]
SNU475 FGG
Mean 1.56
Standard deviation 0.22
Values 1.4 1.7
[6]
THLE FGG
Mean 0.473
Standard deviation 0.016
Values 0.46 0.48
[7]
liver FGG
Mean 8.17e+03
Standard deviation 4.2e+03
Values 5.8e+03 7.5e+03 1.4e+04 5.1e+03
[8]
ref_hepatocyte FGA
Mean 6.91e+03
Standard deviation 9.4e+03
Values 4.5e+02 63 4.3e+02 2.1e+04 1.3e+04
[9]
HepG2 FGA
Mean 200
Standard deviation 1.3e+02
Values 1.1e+02 2.9e+02
[10]
HepG2.C3A FGA
Mean 232
Standard deviation 52
Values 2.7e+02 2e+02
[11]
HuH.7 FGA
Mean 342
Standard deviation 2.4e+02
Values 2e+02 6.2e+02 2e+02
[12]
SNU475 FGA
Mean 2.2
Standard deviation 0.085
Values 2.3 2.1
[13]
THLE FGA
Mean 0.381
Standard deviation 0.064
Values 0.43 0.34
[14]
liver FGA
Mean 1.06e+04
Standard deviation 2.8e+03
Values 7.3e+03 1.4e+04 1e+04 1.1e+04
[15]
ref_hepatocyte FGB
Mean 4.4e+03
Standard deviation 5.7e+03
Values 3.6e+02 3.3e+02 3.9e+02 1.2e+04 8.4e+03
[16]
HepG2 FGB
Mean 55
Standard deviation 32
Values 33 77
[17]
HepG2.C3A FGB
Mean 86.5
Standard deviation 3.3
Values 84 89
[18]
HuH.7 FGB
Mean 431
Standard deviation 3.8e+02
Values 1.9e+02 8.7e+02 2.3e+02
[19]
SNU475 FGB
Mean 5.14
Standard deviation 3.4
Values 2.7 7.6
[20]
THLE FGB
Mean 0.624
Standard deviation 0.0046
Values 0.62 0.63
[21]
liver FGB
Mean 1.16e+04
Standard deviation 4.8e+03
Values 9.6e+03 1.1e+04 1.8e+04 7.3e+03
[22]
ref_hepatocyte ACTB
Mean 1.3e+03
Standard deviation 6.4e+02
Values 1.6e+03 1.8e+03 1.9e+03 6.8e+02 5.5e+02
[23]
HepG2 ACTB
Mean 1.1e+03
Standard deviation 45
Values 1.1e+03 1.1e+03
[24]
HepG2.C3A ACTB
Mean 609
Standard deviation 6.4
Values 6e+02 6.1e+02
[25]
HuH.7 ACTB
Mean 903
Standard deviation 3.5e+02
Values 1.1e+03 5e+02 1.1e+03
[26]
SNU475 ACTB
Mean 1.2e+03
Standard deviation 5e+02
Values 1.6e+03 8.5e+02
[27]
THLE ACTB
Mean 1.03e+03
Standard deviation 3.2e+02
Values 8.1e+02 1.3e+03
[28]
liver ACTB
Mean 816
Standard deviation 6.8e+02
Values 1.2e+03 2.3e+02 1.6e+03 2.7e+02
[29]
ref_hepatocyte ACTG1
Mean 733
Standard deviation 4e+02
Values 1.1e+03 1e+03 9.5e+02 3.5e+02 2.4e+02
[30]
HepG2 ACTG1
Mean 1.5e+03
Standard deviation 1.8e+02
Values 1.6e+03 1.4e+03
[31]
HepG2.C3A ACTG1
Mean 534
Standard deviation 1.5e+02
Values 6.4e+02 4.3e+02
[32]
HuH.7 ACTG1
Mean 549
Standard deviation 1.6e+02
Values 6.7e+02 3.7e+02 6e+02
[33]
SNU475 ACTG1
Mean 591
Standard deviation 2.2e+02
Values 7.5e+02 4.3e+02
[34]
THLE ACTG1
Mean 872
Standard deviation 1.9e+02
Values 7.3e+02 1e+03
[35]
liver ACTG1
Mean 273
Standard deviation 78
Values 3.2e+02 1.9e+02 3.6e+02 2.2e+02
[36]
ref_hepatocyte PEBP1
Mean 629
Standard deviation 4.9e+02
Values 1.1e+03 1.7e+02 63 7.4e+02 1.1e+03
[37]
HepG2 PEBP1
Mean 387
Standard deviation 1.1e+02
Values 3.1e+02 4.7e+02
[38]
HepG2.C3A PEBP1
Mean 441
Standard deviation 17
Values 4.3e+02 4.5e+02
[39]
HuH.7 PEBP1
Mean 209
Standard deviation 28
Values 2e+02 1.9e+02 2.4e+02
[40]
SNU475 PEBP1
Mean 41.7
Standard deviation 11
Values 49 34
[41]
THLE PEBP1
Mean 69.9
Standard deviation 7.3
Values 65 75
[42]
liver PEBP1
Mean 541
Standard deviation 4.8e+02
Values 1.1e+03 1.4e+02 7.1e+02 1.7e+02
[43]
ref_hepatocyte FN1
Mean 152
Standard deviation 1.4e+02
Values 1.3e+02 57 27 1.7e+02 3.8e+02
[44]
HepG2 FN1
Mean 3.78e+03
Standard deviation 3.9e+02
Values 4.1e+03 3.5e+03
[45]
HepG2.C3A FN1
Mean 2.34e+03
Standard deviation 1.3e+03
Values 3.2e+03 1.4e+03
[46]
HuH.7 FN1
Mean 2.08e+03
Standard deviation 9.6e+02
Values 1.8e+03 3.1e+03 1.3e+03
[47]
SNU475 FN1
Mean 2.11e+03
Standard deviation 1.4e+02
Values 2e+03 2.2e+03
[48]
THLE FN1
Mean 2.73e+03
Standard deviation 1.5e+03
Values 1.7e+03 3.8e+03
[49]
liver FN1
Mean 1.06e+03
Standard deviation 3.8e+02
Values 5.9e+02 1.3e+03 9.3e+02 1.4e+03
[50]
ref_hepatocyte RAP1B
Mean 100
Standard deviation 77
Values 1.1e+02 2.1e+02 1.3e+02 25 29
[51]
HepG2 RAP1B
Mean 44.7
Standard deviation 8.8
Values 39 51
[52]
HepG2.C3A RAP1B
Mean 61.1
Standard deviation 18
Values 48 74
[53]
HuH.7 RAP1B
Mean 50.2
Standard deviation 5.6
Values 52 44 54
[54]
SNU475 RAP1B
Mean 128
Standard deviation 17
Values 1.4e+02 1.2e+02
[55]
THLE RAP1B
Mean 121
Standard deviation 4
Values 1.2e+02 1.2e+02
[56]
liver RAP1B
Mean 38.3
Standard deviation 18
Values 53 27 54 20
[57]
ref_hepatocyte PHB
Mean 76
Standard deviation 15
Values 69 1e+02 70 78 62
[58]
HepG2 PHB
Mean 178
Standard deviation 2.8
Values 1.8e+02 1.8e+02
[59]
HepG2.C3A PHB
Mean 146
Standard deviation 41
Values 1.2e+02 1.8e+02
[60]
HuH.7 PHB
Mean 94.8
Standard deviation 36
Values 1e+02 55 1.2e+02
[61]
SNU475 PHB
Mean 58.5
Standard deviation 7.6
Values 53 64
[62]
THLE PHB
Mean 66.4
Standard deviation 7.6
Values 61 72
[63]
liver PHB
Mean 53.9
Standard deviation 28
Values 72 36 84 25
[64]
ref_hepatocyte YWHAB
Mean 42.6
Standard deviation 20
Values 74 47 41 28 22
[65]
HepG2 YWHAB
Mean 193
Standard deviation 37
Values 1.7e+02 2.2e+02
[66]
HepG2.C3A YWHAB
Mean 141
Standard deviation 27
Values 1.2e+02 1.6e+02
[67]
HuH.7 YWHAB
Mean 82.2
Standard deviation 26
Values 98 52 97
[68]
SNU475 YWHAB
Mean 193
Standard deviation 7
Values 2e+02 1.9e+02
[69]
THLE YWHAB
Mean 146
Standard deviation 23
Values 1.3e+02 1.6e+02
[70]
liver YWHAB
Mean 56.6
Standard deviation 26
Values 78 39 80 30
[71]
ref_hepatocyte CALM1
Mean 29.2
Standard deviation 11
Values 17 40 21 28 40
[72]
HepG2 CALM1
Mean 67.9
Standard deviation 4.3
Values 65 71
[73]
HepG2.C3A CALM1
Mean 62
Standard deviation 16
Values 51 73
[74]
HuH.7 CALM1
Mean 81.9
Standard deviation 15
Values 90 64 92
[75]
SNU475 CALM1
Mean 160
Standard deviation 24
Values 1.8e+02 1.4e+02
[76]
THLE CALM1
Mean 109
Standard deviation 13
Values 1e+02 1.2e+02
[77]
liver CALM1
Mean 127
Standard deviation 70
Values 2.1e+02 80 1.7e+02 57
[78]
ref_hepatocyte MAP2K1
Mean 28.1
Standard deviation 8.6
Values 27 39 32 15 27
[79]
HepG2 MAP2K1
Mean 32.6
Standard deviation 3.7
Values 35 30
[80]
HepG2.C3A MAP2K1
Mean 23.1
Standard deviation 0.39
Values 23 23
[81]
HuH.7 MAP2K1
Mean 33.2
Standard deviation 6.4
Values 33 27 40
[82]
SNU475 MAP2K1
Mean 35.5
Standard deviation 5.2
Values 32 39
[83]
THLE MAP2K1
Mean 56.5
Standard deviation 3.6
Values 54 59
[84]
liver MAP2K1
Mean 17.5
Standard deviation 8
Values 28 11 18 12
[85]
ref_hepatocyte MAP2K2
Mean 27.7
Standard deviation 8.5
Values 22 20 28 42 26
[86]
HepG2 MAP2K2
Mean 63.6
Standard deviation 21
Values 79 48
[87]
HepG2.C3A MAP2K2
Mean 45.2
Standard deviation 14
Values 55 36
[88]
HuH.7 MAP2K2
Mean 79.3
Standard deviation 9.5
Values 87 82 69
[89]
SNU475 MAP2K2
Mean 28.4
Standard deviation 0.16
Values 28 28
[90]
THLE MAP2K2
Mean 44.5
Standard deviation 0.75
Values 44 45
[91]
liver MAP2K2
Mean 12.1
Standard deviation 3
Values 17 11 9.8 11
[92]
ref_hepatocyte RAP1A
Mean 17.1
Standard deviation 7.2
Values 17 20 8.5 13 28
[93]
HepG2 RAP1A
Mean 18.3
Standard deviation 5.4
Values 14 22
[94]
HepG2.C3A RAP1A
Mean 15.6
Standard deviation 1.3
Values 15 17
[95]
HuH.7 RAP1A
Mean 26.7
Standard deviation 1.9
Values 25 29 26
[96]
SNU475 RAP1A
Mean 27.1
Standard deviation 7
Values 32 22
[97]
THLE RAP1A
Mean 25.7
Standard deviation 2.2
Values 24 27
[98]
liver RAP1A
Mean 9.95
Standard deviation 5.1
Values 17 7.4 10 5.3
[99]
ref_hepatocyte RAF1
Mean 15.5
Standard deviation 5.7
Values 6 14 20 20 17
[100]
HepG2 RAF1
Mean 32.7
Standard deviation 5.2
Values 29 36
[101]
HepG2.C3A RAF1
Mean 38.6
Standard deviation 2.8
Values 41 37
[102]
HuH.7 RAF1
Mean 89
Standard deviation 4.2
Values 85 93 89
[103]
SNU475 RAF1
Mean 25
Standard deviation 4.6
Values 22 28
[104]
THLE RAF1
Mean 50.9
Standard deviation 5.2
Values 47 55
[105]
liver RAF1
Mean 47
Standard deviation 3.6
Values 51 42 49 46
[106]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[107]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[108]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[109]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[110]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[111]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[112]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[113]
ref_hepatocyte ARAF
Mean 12.3
Standard deviation 8
Values 4.1 4 13 21 19
[114]
HepG2 ARAF
Mean 19.8
Standard deviation 1.6
Values 21 19
[115]
HepG2.C3A ARAF
Mean 14.3
Standard deviation 2.2
Values 16 13
[116]
HuH.7 ARAF
Mean 16.5
Standard deviation 1.9
Values 18 14 17
[117]
SNU475 ARAF
Mean 21.1
Standard deviation 1.4
Values 22 20
[118]
THLE ARAF
Mean 24.2
Standard deviation 1.6
Values 23 25
[119]
liver ARAF
Mean 32.1
Standard deviation 23
Values 50 11 54 13
[120]
ref_hepatocyte TLN1
Mean 12
Standard deviation 5.9
Values 7.9 19 17 9.4 6.1
[121]
HepG2 TLN1
Mean 210
Standard deviation 7.2
Values 2.1e+02 2.2e+02
[122]
HepG2.C3A TLN1
Mean 72.3
Standard deviation 9.8
Values 79 65
[123]
HuH.7 TLN1
Mean 119
Standard deviation 39
Values 1.6e+02 1e+02 90
[124]
SNU475 TLN1
Mean 189
Standard deviation 61
Values 2.3e+02 1.5e+02
[125]
THLE TLN1
Mean 215
Standard deviation 62
Values 1.7e+02 2.6e+02
[126]
liver TLN1
Mean 174
Standard deviation 66
Values 87 2.4e+02 1.7e+02 2e+02
[127]
ref_hepatocyte VCL
Mean 11.9
Standard deviation 12
Values 7.3 25 23 1.9 1.9
[128]
HepG2 VCL
Mean 45
Standard deviation 4.2
Values 42 48
[129]
HepG2.C3A VCL
Mean 32.9
Standard deviation 6.1
Values 37 29
[130]
HuH.7 VCL
Mean 34.7
Standard deviation 5.9
Values 40 36 28
[131]
SNU475 VCL
Mean 156
Standard deviation 22
Values 1.7e+02 1.4e+02
[132]
THLE VCL
Mean 93.4
Standard deviation 22
Values 78 1.1e+02
[133]
liver VCL
Mean 29.6
Standard deviation 13
Values 11 35 32 41
[134]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[135]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[136]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[137]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[138]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[139]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[140]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[141]
ref_hepatocyte APBB1IP
Mean 11.5
Standard deviation 7.7
Values 0 20 8.1 15 15
[142]
HepG2 APBB1IP
Mean 0.0688
Standard deviation 0.097
Values 0.14 0
[143]
HepG2.C3A APBB1IP
Mean 0
Standard deviation 0
Values 0 0
[144]
HuH.7 APBB1IP
Mean 0.223
Standard deviation 0.3
Values 0.049 0.56 0.056
[145]
SNU475 APBB1IP
Mean 2.15
Standard deviation 0.36
Values 1.9 2.4
[146]
THLE APBB1IP
Mean 0.354
Standard deviation 0.11
Values 0.43 0.28
[147]
liver APBB1IP
Mean 11.3
Standard deviation 1.6
Values 12 9.3 11 13
[148]
ref_hepatocyte MAP3K11
Mean 10.8
Standard deviation 3.8
Values 16 7.7 6.1 13 12
[149]
HepG2 MAP3K11
Mean 50.5
Standard deviation 6.9
Values 46 55
[150]
HepG2.C3A MAP3K11
Mean 43.3
Standard deviation 11
Values 51 35
[151]
HuH.7 MAP3K11
Mean 32
Standard deviation 5.2
Values 38 28 30
[152]
SNU475 MAP3K11
Mean 21.9
Standard deviation 1.7
Values 23 21
[153]
THLE MAP3K11
Mean 22.3
Standard deviation 1.7
Values 21 23
[154]
liver MAP3K11
Mean 21
Standard deviation 5.1
Values 24 19 15 26
[155]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 14 13 13 6.1 7.4
[156]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 62 93
[157]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 71 81
[158]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 73 60 61
[159]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 77 65
[160]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[161]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 39 68 41 61
[162]
ref_hepatocyte CSK
Mean 10.6
Standard deviation 1.8
Values 11 8.9 13 9 11
[163]
HepG2 CSK
Mean 30.4
Standard deviation 3.7
Values 33 28
[164]
HepG2.C3A CSK
Mean 19.1
Standard deviation 3
Values 21 17
[165]
HuH.7 CSK
Mean 23.7
Standard deviation 5.3
Values 27 18 26
[166]
SNU475 CSK
Mean 19.3
Standard deviation 0.29
Values 19 20
[167]
THLE CSK
Mean 16.3
Standard deviation 1.9
Values 15 18
[168]
liver CSK
Mean 8.27
Standard deviation 2.7
Values 7.6 6.5 6.7 12
[169]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[170]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[171]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[172]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[173]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[174]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[175]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[176]
ref_hepatocyte MARK3
Mean 8.81
Standard deviation 4
Values 6.9 13 14 6.1 4.9
[177]
HepG2 MARK3
Mean 18.5
Standard deviation 2.2
Values 17 20
[178]
HepG2.C3A MARK3
Mean 19.8
Standard deviation 0.88
Values 20 19
[179]
HuH.7 MARK3
Mean 18.8
Standard deviation 1.9
Values 18 17 21
[180]
SNU475 MARK3
Mean 35.5
Standard deviation 3.7
Values 33 38
[181]
THLE MARK3
Mean 32
Standard deviation 0.32
Values 32 32
[182]
liver MARK3
Mean 15.1
Standard deviation 6.7
Values 11 22 8.1 20
[183]
ref_hepatocyte ARRB2
Mean 7.58
Standard deviation 4.1
Values 14 4.4 3.6 8.2 7.8
[184]
HepG2 ARRB2
Mean 18.8
Standard deviation 5.4
Values 23 15
[185]
HepG2.C3A ARRB2
Mean 21.9
Standard deviation 3.9
Values 25 19
[186]
HuH.7 ARRB2
Mean 20.3
Standard deviation 3.2
Values 20 17 23
[187]
SNU475 ARRB2
Mean 5.59
Standard deviation 0.33
Values 5.4 5.8
[188]
THLE ARRB2
Mean 10.9
Standard deviation 0.23
Values 11 11
[189]
liver ARRB2
Mean 5.88
Standard deviation 3.8
Values 9.3 2.5 9.1 2.6
[190]
ref_hepatocyte CAMK2D
Mean 6.27
Standard deviation 4.6
Values 12 11 1.6 2.7 4.7
[191]
HepG2 CAMK2D
Mean 15.2
Standard deviation 5.9
Values 11 19
[192]
HepG2.C3A CAMK2D
Mean 16.7
Standard deviation 1.9
Values 15 18
[193]
HuH.7 CAMK2D
Mean 46.1
Standard deviation 5.5
Values 51 47 40
[194]
SNU475 CAMK2D
Mean 18.4
Standard deviation 4.5
Values 22 15
[195]
THLE CAMK2D
Mean 11.8
Standard deviation 1.2
Values 13 11
[196]
liver CAMK2D
Mean 23.7
Standard deviation 6.1
Values 33 21 22 19
[197]
ref_hepatocyte IQGAP1
Mean 4.76
Standard deviation 3
Values 8.8 6 5.4 0.97 2.7
[198]
HepG2 IQGAP1
Mean 38
Standard deviation 13
Values 29 47
[199]
HepG2.C3A IQGAP1
Mean 24.7
Standard deviation 3.2
Values 22 27
[200]
HuH.7 IQGAP1
Mean 31.6
Standard deviation 8.7
Values 42 28 26
[201]
SNU475 IQGAP1
Mean 137
Standard deviation 20
Values 1.5e+02 1.2e+02
[202]
THLE IQGAP1
Mean 138
Standard deviation 22
Values 1.2e+02 1.5e+02
[203]
liver IQGAP1
Mean 27.5
Standard deviation 11
Values 17 40 18 35
[204]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 5.1 2.8 3.6 6 3.3
[205]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 37 29
[206]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 39 22
[207]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 34 25 32
[208]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 12 8.5
[209]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[210]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 5 0.81 4.8 0.82
[211]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[212]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[213]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[214]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[215]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[216]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[217]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[218]
ref_hepatocyte BRAP
Mean 3.21
Standard deviation 1.1
Values 4.5 3 3.9 2.8 1.8
[219]
HepG2 BRAP
Mean 9.06
Standard deviation 1.2
Values 8.2 9.9
[220]
HepG2.C3A BRAP
Mean 9.29
Standard deviation 2
Values 7.9 11
[221]
HuH.7 BRAP
Mean 9.44
Standard deviation 0.52
Values 9.4 8.9 10
[222]
SNU475 BRAP
Mean 10.8
Standard deviation 1.1
Values 10 12
[223]
THLE BRAP
Mean 13.2
Standard deviation 0.98
Values 12 14
[224]
liver BRAP
Mean 7.63
Standard deviation 0.83
Values 7.1 8.6 8 6.8
[225]
ref_hepatocyte CAMK2G
Mean 2.9
Standard deviation 1.2
Values 2.8 2.3 4.9 1.9 2.6
[226]
HepG2 CAMK2G
Mean 11
Standard deviation 0.61
Values 11 11
[227]
HepG2.C3A CAMK2G
Mean 22.6
Standard deviation 3.2
Values 25 20
[228]
HuH.7 CAMK2G
Mean 16.6
Standard deviation 0.56
Values 16 17 17
[229]
SNU475 CAMK2G
Mean 17.1
Standard deviation 1.1
Values 18 16
[230]
THLE CAMK2G
Mean 14.2
Standard deviation 0.22
Values 14 14
[231]
liver CAMK2G
Mean 7.98
Standard deviation 1
Values 9.1 7 7.2 8.6
[232]
ref_hepatocyte ITGB3
Mean 1.08
Standard deviation 1.3
Values 0 2.5 2.6 0.15 0.24
[233]
HepG2 ITGB3
Mean 0.771
Standard deviation 0.028
Values 0.79 0.75
[234]
HepG2.C3A ITGB3
Mean 0.105
Standard deviation 0.058
Values 0.15 0.064
[235]
HuH.7 ITGB3
Mean 1.16
Standard deviation 0.088
Values 1.2 1.2 1.1
[236]
SNU475 ITGB3
Mean 14.3
Standard deviation 13
Values 5.4 23
[237]
THLE ITGB3
Mean 12.8
Standard deviation 1.3
Values 14 12
[238]
liver ITGB3
Mean 3.86
Standard deviation 3.6
Values 0.66 8.8 1.7 4.2
[239]
ref_hepatocyte BRAF
Mean 1.07
Standard deviation 0.72
Values 0.56 1.2 2.3 0.67 0.67
[240]
HepG2 BRAF
Mean 2.8
Standard deviation 0.62
Values 2.4 3.2
[241]
HepG2.C3A BRAF
Mean 2.07
Standard deviation 0.66
Values 1.6 2.5
[242]
HuH.7 BRAF
Mean 8.12
Standard deviation 5.8
Values 6.4 15 3.4
[243]
SNU475 BRAF
Mean 3.28
Standard deviation 0.16
Values 3.2 3.4
[244]
THLE BRAF
Mean 2.97
Standard deviation 0.38
Values 2.7 3.2
[245]
liver BRAF
Mean 5.48
Standard deviation 2.9
Values 3.1 8 2.9 7.9
[246]
ref_hepatocyte JAK2
Mean 0.762
Standard deviation 0.48
Values 1.3 1.3 0.62 0.18 0.5
[247]
HepG2 JAK2
Mean 1.97
Standard deviation 1.3
Values 1 2.9
[248]
HepG2.C3A JAK2
Mean 1.75
Standard deviation 0.67
Values 1.3 2.2
[249]
HuH.7 JAK2
Mean 1.23
Standard deviation 0.34
Values 1.2 1.6 0.9
[250]
SNU475 JAK2
Mean 2.37
Standard deviation 0.1
Values 2.3 2.4
[251]
THLE JAK2
Mean 4.02
Standard deviation 0.77
Values 4.6 3.5
[252]
liver JAK2
Mean 7.06
Standard deviation 3.8
Values 4.7 11 2.9 9.8
[253]
ref_hepatocyte ARRB1
Mean 0.644
Standard deviation 0.19
Values 0.65 0.54 0.92 0.69 0.41
[254]
HepG2 ARRB1
Mean 17.1
Standard deviation 1.4
Values 18 16
[255]
HepG2.C3A ARRB1
Mean 13.3
Standard deviation 2.1
Values 15 12
[256]
HuH.7 ARRB1
Mean 7.82
Standard deviation 0.6
Values 7.8 8.4 7.3
[257]
SNU475 ARRB1
Mean 5.26
Standard deviation 0.39
Values 5.5 5
[258]
THLE ARRB1
Mean 5.15
Standard deviation 0.95
Values 4.5 5.8
[259]
liver ARRB1
Mean 8.83
Standard deviation 5.7
Values 5 11 3.6 16
[260]
ref_hepatocyte CAMK2B
Mean 0.643
Standard deviation 0.6
Values 0 1.1 0 0.9 1.3
[261]
HepG2 CAMK2B
Mean 0.245
Standard deviation 0.067
Values 0.29 0.2
[262]
HepG2.C3A CAMK2B
Mean 0.0871
Standard deviation 0.013
Values 0.078 0.097
[263]
HuH.7 CAMK2B
Mean 0.0107
Standard deviation 0.0051
Values 0.016 0.0064 0.0094
[264]
SNU475 CAMK2B
Mean 0.162
Standard deviation 0.072
Values 0.21 0.11
[265]
THLE CAMK2B
Mean 0.283
Standard deviation 0.15
Values 0.39 0.18
[266]
liver CAMK2B
Mean 2.02
Standard deviation 0.9
Values 1.5 2.2 3.2 1.2
[267]
ref_hepatocyte CNKSR1
Mean 0.436
Standard deviation 0.37
Values 0.37 0.14 1.1 0.39 0.22
[268]
HepG2 CNKSR1
Mean 4.63
Standard deviation 0.32
Values 4.9 4.4
[269]
HepG2.C3A CNKSR1
Mean 11.5
Standard deviation 4.4
Values 15 8.3
[270]
HuH.7 CNKSR1
Mean 0.638
Standard deviation 0.28
Values 0.56 0.41 0.95
[271]
SNU475 CNKSR1
Mean 0.347
Standard deviation 0.16
Values 0.23 0.46
[272]
THLE CNKSR1
Mean 0.266
Standard deviation 0.083
Values 0.33 0.21
[273]
liver CNKSR1
Mean 0.812
Standard deviation 0.72
Values 1.8 0.27 0.92 0.26
[274]
ref_hepatocyte KSR1
Mean 0.387
Standard deviation 0.39
Values 1 0.34 0.38 0.06 0.11
[275]
HepG2 KSR1
Mean 8.21
Standard deviation 0.63
Values 8.7 7.8
[276]
HepG2.C3A KSR1
Mean 5.95
Standard deviation 0.11
Values 6 5.9
[277]
HuH.7 KSR1
Mean 0.672
Standard deviation 0.25
Values 0.6 0.95 0.47
[278]
SNU475 KSR1
Mean 2.94
Standard deviation 0.81
Values 2.4 3.5
[279]
THLE KSR1
Mean 4.65
Standard deviation 0.57
Values 4.2 5
[280]
liver KSR1
Mean 0.913
Standard deviation 0.48
Values 0.49 1.4 0.51 1.2
[281]
ref_hepatocyte CNKSR2
Mean 0.144
Standard deviation 0.087
Values 0 0.12 0.21 0.18 0.2
[282]
HepG2 CNKSR2
Mean 0.0229
Standard deviation 0.016
Values 0.011 0.034
[283]
HepG2.C3A CNKSR2
Mean 0.0199
Standard deviation 0.013
Values 0.029 0.011
[284]
HuH.7 CNKSR2
Mean 15.2
Standard deviation 1.8
Values 17 14 15
[285]
SNU475 CNKSR2
Mean 3.42
Standard deviation 0.58
Values 3 3.8
[286]
THLE CNKSR2
Mean 1.07
Standard deviation 0.003
Values 1.1 1.1
[287]
liver CNKSR2
Mean 1.78
Standard deviation 0.83
Values 2.7 1.8 0.67 2
[288]
ref_hepatocyte VWF
Mean 0.138
Standard deviation 0.13
Values 0.14 0.026 0 0.32 0.2
[289]
HepG2 VWF
Mean 0.599
Standard deviation 0.15
Values 0.7 0.49
[290]
HepG2.C3A VWF
Mean 0.12
Standard deviation 0.078
Values 0.17 0.064
[291]
HuH.7 VWF
Mean 0.022
Standard deviation 0.031
Values 0.0082 0.058 0
[292]
SNU475 VWF
Mean 0.283
Standard deviation 0.027
Values 0.3 0.26
[293]
THLE VWF
Mean 0.0529
Standard deviation 0.0079
Values 0.047 0.059
[294]
liver VWF
Mean 10.3
Standard deviation 3.3
Values 8.3 10 7.8 15
[295]
ref_hepatocyte ITGA2B
Mean 0.0356
Standard deviation 0.034
Values 0 0.07 0 0.043 0.065
[296]
HepG2 ITGA2B
Mean 0.956
Standard deviation 1
Values 1.7 0.23
[297]
HepG2.C3A ITGA2B
Mean 1.04
Standard deviation 0.35
Values 1.3 0.79
[298]
HuH.7 ITGA2B
Mean 0.994
Standard deviation 0.15
Values 0.93 0.89 1.2
[299]
SNU475 ITGA2B
Mean 0.53
Standard deviation 0.0044
Values 0.53 0.53
[300]
THLE ITGA2B
Mean 0.191
Standard deviation 0.09
Values 0.25 0.13
[301]
liver ITGA2B
Mean 0.311
Standard deviation 0.17
Values 0.38 0.29 0.49 0.093
[302]
ref_hepatocyte KSR2
Mean 0.0263
Standard deviation 0.041
Values 0 0.039 0.092 0 0
[303]
HepG2 KSR2
Mean 0.068
Standard deviation 0.042
Values 0.097 0.039
[304]
HepG2.C3A KSR2
Mean 0.0302
Standard deviation 0.012
Values 0.039 0.021
[305]
HuH.7 KSR2
Mean 0
Standard deviation 0
Values 0 0 0
[306]
SNU475 KSR2
Mean 0.0201
Standard deviation 0.022
Values 0.0046 0.035
[307]
THLE KSR2
Mean 0
Standard deviation 0
Values 0 0
[308]
liver KSR2
Mean 0.0927
Standard deviation 0.043
Values 0.071 0.16 0.077 0.066
[309]
ref_hepatocyte CAMK2A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[310]
HepG2 CAMK2A
Mean 0.0787
Standard deviation 0.022
Values 0.063 0.094
[311]
HepG2.C3A CAMK2A
Mean 0.0468
Standard deviation 0.025
Values 0.029 0.064
[312]
HuH.7 CAMK2A
Mean 0.0232
Standard deviation 0.016
Values 0.041 0.019 0.0094
[313]
SNU475 CAMK2A
Mean 1.25
Standard deviation 0.78
Values 1.8 0.69
[314]
THLE CAMK2A
Mean 0.231
Standard deviation 0.034
Values 0.21 0.26
[315]
liver CAMK2A
Mean 0.0104
Standard deviation 0.014
Values 0 0.029 0 0.013