REACTOME_SIGNALING_BY_MAPK_MUTANTS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 DUSP6 Dual specificity protein phosphatase 6 [1] -2.19[2] -0.55[3] -0.44[4] -3.80[5] -0.26[6] -0.44[7]
2 MAPK1 Mitogen-activated protein kinase 1 [8] 0.01[9] -0.30[10] 0.36[11] 1.96[12] 1.36[13] 1.08[14]
3 DUSP9 Dual specificity protein phosphatase 9 [15] 1.76[16] 1.66[17] 0.98[18] -4.91[19] -5.31[20] -4.97[21]
4 DUSP16 Dual specificity protein phosphatase 16 [22] -0.13[23] -0.56[24] 0.01[25] -1.29[26] -0.64[27] 0.75[28]
5 DUSP10 Dual specificity protein phosphatase 10 [29] -4.70[30] -5.90[31] -3.62[32] -0.69[33] -1.93[34] -0.69[35]
6 DUSP8 Dual specificity protein phosphatase 8 [36] -0.56[37] -1.57[38] -1.55[39] -1.32[40] -0.99[41] -4.52[42]
7 DUSP7 Dual specificity protein phosphatase 7 [43] -0.15[44] -1.51[45] 0.57[46] -0.32[47] 1.82[48] -0.67[49]
[1]
ref_hepatocyte DUSP6
Mean 15.3
Standard deviation 12
Values 1.5 4.5 29 26 15
[2]
HepG2 DUSP6
Mean 24.2
Standard deviation 10
Values 31 17
[3]
HepG2.C3A DUSP6
Mean 91
Standard deviation 18
Values 1e+02 78
[4]
HuH.7 DUSP6
Mean 52.9
Standard deviation 18
Values 62 32 65
[5]
SNU475 DUSP6
Mean 1.87
Standard deviation 2.3
Values 0.26 3.5
[6]
THLE DUSP6
Mean 28.9
Standard deviation 3.7
Values 26 32
[7]
liver DUSP6
Mean 25.9
Standard deviation 9.5
Values 38 19 28 18
[8]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 14 13 13 6.1 7.4
[9]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 62 93
[10]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 71 81
[11]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 73 60 61
[12]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 77 65
[13]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[14]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 39 68 41 61
[15]
ref_hepatocyte DUSP9
Mean 8.55
Standard deviation 19
Values 42 0 0.022 0.06 0.16
[16]
HepG2 DUSP9
Mean 207
Standard deviation 22
Values 2.2e+02 1.9e+02
[17]
HepG2.C3A DUSP9
Mean 236
Standard deviation 24
Values 2.5e+02 2.2e+02
[18]
HuH.7 DUSP9
Mean 79
Standard deviation 11
Values 67 87 83
[19]
SNU475 DUSP9
Mean 0.485
Standard deviation 0.1
Values 0.41 0.56
[20]
THLE DUSP9
Mean 0.487
Standard deviation 0.019
Values 0.47 0.5
[21]
liver DUSP9
Mean 0.625
Standard deviation 0.59
Values 0.82 0.2 0.1 1.4
[22]
ref_hepatocyte DUSP16
Mean 7.61
Standard deviation 4
Values 4.7 12 12 6.1 3.5
[23]
HepG2 DUSP16
Mean 49.8
Standard deviation 0.41
Values 50 50
[24]
HepG2.C3A DUSP16
Mean 44.8
Standard deviation 6.7
Values 50 40
[25]
HuH.7 DUSP16
Mean 35.9
Standard deviation 14
Values 33 51 24
[26]
SNU475 DUSP16
Mean 5.29
Standard deviation 0.16
Values 5.4 5.2
[27]
THLE DUSP16
Mean 11.1
Standard deviation 0.034
Values 11 11
[28]
liver DUSP16
Mean 29.5
Standard deviation 18
Values 14 47 14 43
[29]
ref_hepatocyte DUSP10
Mean 7.44
Standard deviation 3.9
Values 1.9 7.2 5.9 12 10
[30]
HepG2 DUSP10
Mean 2.05
Standard deviation 0.45
Values 2.4 1.7
[31]
HepG2.C3A DUSP10
Mean 1.09
Standard deviation 0.49
Values 1.4 0.74
[32]
HuH.7 DUSP10
Mean 2.85
Standard deviation 1.9
Values 1.8 5.1 1.6
[33]
SNU475 DUSP10
Mean 7.88
Standard deviation 4.2
Values 11 4.9
[34]
THLE DUSP10
Mean 4.44
Standard deviation 0.4
Values 4.2 4.7
[35]
liver DUSP10
Mean 10.6
Standard deviation 2.1
Values 14 8.9 10 9.7
[36]
ref_hepatocyte DUSP8
Mean 1.65
Standard deviation 1.8
Values 1.4 1.4 4.7 0.78 0
[37]
HepG2 DUSP8
Mean 8.05
Standard deviation 3
Values 10 5.9
[38]
HepG2.C3A DUSP8
Mean 4.84
Standard deviation 3.1
Values 7.1 2.6
[39]
HuH.7 DUSP8
Mean 2.64
Standard deviation 2.5
Values 1.2 5.5 1.2
[40]
SNU475 DUSP8
Mean 1.13
Standard deviation 0.22
Values 1.3 0.97
[41]
THLE DUSP8
Mean 1.88
Standard deviation 0.61
Values 2.3 1.5
[42]
liver DUSP8
Mean 0.165
Standard deviation 0.085
Values 0.12 0.086 0.18 0.28
[43]
ref_hepatocyte DUSP7
Mean 1.21
Standard deviation 1.1
Values 1.2 0.72 3.1 0.56 0.45
[44]
HepG2 DUSP7
Mean 7.84
Standard deviation 0.41
Values 8.1 7.6
[45]
HepG2.C3A DUSP7
Mean 3.71
Standard deviation 0.37
Values 3.5 4
[46]
HuH.7 DUSP7
Mean 8.47
Standard deviation 1.7
Values 9.6 6.5 9.2
[47]
SNU475 DUSP7
Mean 1.66
Standard deviation 0.53
Values 1.3 2
[48]
THLE DUSP7
Mean 9.74
Standard deviation 1.7
Values 8.5 11
[49]
liver DUSP7
Mean 1.76
Standard deviation 0.63
Values 2.3 1.3 1.2 2.3