REACTOME_SIGNALING_BY_LRP5_MUTANTS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 LRP5 Low-density lipoprotein receptor-related protein 5 [1] -1.11[2] 0.00[3] 0.11[4] 0.09[5] -1.50[6] 0.39[7]
2 KREMEN1 Kremen protein 1 [8] -0.20[9] -0.01[10] -0.46[11] -0.09[12] -0.43[13] -1.42[14]
3 DKK1 Dickkopf-related protein 1 [15] 2.06[16] -0.20[17] -0.26[18] -0.32[19] 2.32[20] -7.21[21]
4 DKK4 Dickkopf-related protein 4 [22] -1.66[23] -0.14[24] [25] [26] -8.96[27] -4.95[28]
5 KREMEN2 Kremen protein 2 [29] 4.67[30] 5.11[31] 4.80[32] 1.35[33] 3.53[34] -2.57[35]
6 DKK2 Dickkopf-related protein 2 [36] [37] [38] [39] [40] [41] [42]
[1]
ref_hepatocyte LRP5
Mean 11.4
Standard deviation 3.9
Values 8.8 10 7.3 17 13
[2]
HepG2 LRP5
Mean 108
Standard deviation 24
Values 1.3e+02 91
[3]
HepG2.C3A LRP5
Mean 79.2
Standard deviation 20
Values 93 65
[4]
HuH.7 LRP5
Mean 117
Standard deviation 36
Values 1.5e+02 81 1.2e+02
[5]
SNU475 LRP5
Mean 69.8
Standard deviation 26
Values 88 52
[6]
THLE LRP5
Mean 28.3
Standard deviation 7.2
Values 23 33
[7]
liver LRP5
Mean 71.8
Standard deviation 33
Values 39 93 50 1.1e+02
[8]
ref_hepatocyte KREMEN1
Mean 2.07
Standard deviation 2.5
Values 6.3 2.3 0.9 0.26 0.59
[9]
HepG2 KREMEN1
Mean 37.1
Standard deviation 7.2
Values 42 32
[10]
HepG2.C3A KREMEN1
Mean 14.3
Standard deviation 0.73
Values 15 14
[11]
HuH.7 KREMEN1
Mean 14.4
Standard deviation 4.7
Values 19 9.5 15
[12]
SNU475 KREMEN1
Mean 11.2
Standard deviation 4.3
Values 14 8.2
[13]
THLE KREMEN1
Mean 10.8
Standard deviation 1.1
Values 10 12
[14]
liver KREMEN1
Mean 3.73
Standard deviation 1.9
Values 3.3 4.2 1.4 6.1
[15]
ref_hepatocyte DKK1
Mean 2
Standard deviation 4.1
Values 9.3 0.59 0 0 0.089
[16]
HepG2 DKK1
Mean 172
Standard deviation 31
Values 1.5e+02 1.9e+02
[17]
HepG2.C3A DKK1
Mean 12.2
Standard deviation 9
Values 5.8 19
[18]
HuH.7 DKK1
Mean 16.1
Standard deviation 6.9
Values 19 8.2 21
[19]
SNU475 DKK1
Mean 9.29
Standard deviation 1.1
Values 8.5 10
[20]
THLE DKK1
Mean 70.4
Standard deviation 23
Values 54 87
[21]
liver DKK1
Mean 0.0656
Standard deviation 0.079
Values 0 0.043 0.18 0.04
[22]
ref_hepatocyte DKK4
Mean 0.21
Standard deviation 0.38
Values 0.88 0 0 0.17 0
[23]
HepG2 DKK4
Mean 1.37
Standard deviation 1.4
Values 0.41 2.3
[24]
HepG2.C3A DKK4
Mean 1.32
Standard deviation 1.1
Values 0.57 2.1
[25]
HuH.7 DKK4
Mean 0
Standard deviation 0
Values 0 0 0
[26]
SNU475 DKK4
Mean 0
Standard deviation 0
Values 0 0
[27]
THLE DKK4
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[28]
liver DKK4
Mean 0.0328
Standard deviation 0.049
Values 0 0.029 0.1 0
[29]
ref_hepatocyte KREMEN2
Mean 0.00813
Standard deviation 0.018
Values 0 0 0 0 0.041
[30]
HepG2 KREMEN2
Mean 4.27
Standard deviation 2.5
Values 6.1 2.5
[31]
HepG2.C3A KREMEN2
Mean 1.95
Standard deviation 0.63
Values 1.5 2.4
[32]
HuH.7 KREMEN2
Mean 2.17
Standard deviation 0.96
Values 2.1 1.3 3.2
[33]
SNU475 KREMEN2
Mean 0.12
Standard deviation 0.031
Values 0.097 0.14
[34]
THLE KREMEN2
Mean 0.662
Standard deviation 0.026
Values 0.68 0.64
[35]
liver KREMEN2
Mean 0.00662
Standard deviation 0.013
Values 0 0 0 0.026
[36]
ref_hepatocyte DKK2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[37]
HepG2 DKK2
Mean 0.0258
Standard deviation 0.012
Values 0.017 0.034
[38]
HepG2.C3A DKK2
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 DKK2
Mean 0
Standard deviation 0
Values 0 0 0
[40]
SNU475 DKK2
Mean 0.137
Standard deviation 0.05
Values 0.1 0.17
[41]
THLE DKK2
Mean 0.026
Standard deviation 0.022
Values 0.041 0.011
[42]
liver DKK2
Mean 0.0557
Standard deviation 0.044
Values 0.12 0.014 0.051 0.04