REACTOME_SIGNALING_BY_INSULIN_RECEPTOR Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ATP6V0E1 V-type proton ATPase subunit e 1 [1] -1.60[2] -2.37[3] -2.41[4] -1.50[5] -1.89[6] -1.66[7]
2 ATP6V0B V-type proton ATPase 21 kDa proteolipid subunit [8] -1.79[9] -1.71[10] -2.43[11] -1.89[12] -1.46[13] -1.08[14]
3 ATP6V0C V-type proton ATPase 16 kDa proteolipid subunit [15] -1.37[16] -1.91[17] -2.16[18] -2.04[19] -1.19[20] -1.98[21]
4 ATP6V1G1 V-type proton ATPase subunit G 1 [22] -0.95[23] -0.95[24] -1.32[25] -1.02[26] -0.76[27] -0.97[28]
5 ATP6V1F V-type proton ATPase subunit F [29] -1.48[30] -1.77[31] -1.93[32] -1.61[33] -1.48[34] -2.32[35]
6 ATP6V1E1 V-type proton ATPase subunit E 1 [36] -0.68[37] -0.88[38] -0.87[39] -0.28[40] -0.19[41] -1.99[42]
7 TRIB3 Tribbles homolog 3 [43] 0.66[44] 0.85[45] -0.44[46] -2.19[47] -1.62[48] -0.80[49]
8 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [50] 0.20[51] 0.52[52] 0.31[53] 0.71[54] 1.40[55] 0.88[56]
9 ATP6AP1 V-type proton ATPase subunit S1 [57] 0.27[58] -0.10[59] -0.05[60] -0.27[61] 0.29[62] -0.79[63]
10 ATP6V0D1 V-type proton ATPase subunit d 1 [64] -0.52[65] -1.10[66] -0.89[67] -0.24[68] -0.35[69] -0.36[70]
11 GRB2 Growth factor receptor-bound protein 2 [71] 0.95[72] 0.68[73] 0.63[74] 0.38[75] 0.35[76] -0.08[77]
12 ATP6V1B2 V-type proton ATPase subunit B, brain isoform [78] -0.08[79] -0.24[80] 0.08[81] -0.41[82] 0.01[83] -0.36[84]
13 ATP6V1D V-type proton ATPase subunit D [85] -1.03[86] -1.33[87] -2.06[88] -0.27[89] 0.21[90] -1.22[91]
14 SHC1 SHC-transforming protein 1 [92] 0.91[93] 1.03[94] 0.93[95] 2.47[96] 2.02[97] 0.40[98]
15 ATP6V0E2 V-type proton ATPase subunit e 2 [99] 0.35[100] 0.58[101] -6.93[102] -1.03[103] -1.97[104] -0.18[105]
16 FGFR4 Fibroblast growth factor receptor 4 [106] 1.71[107] 1.94[108] 2.35[109] -4.41[110] -4.48[111] 0.12[112]
17 NRAS GTPase NRas [113] 0.38[114] 0.71[115] 0.95[116] 0.82[117] 0.45[118] -0.63[119]
18 HRAS GTPase HRas [120] -1.26[121] -2.07[122] -3.03[123] -1.13[124] -1.28[125] -3.04[126]
19 MAPK1 Mitogen-activated protein kinase 1 [127] 1.46[128] 1.49[129] 1.15[130] 1.67[131] 1.38[132] 1.40[133]
20 ATP6V1A V-type proton ATPase catalytic subunit A [134] 0.12[135] 0.33[136] 0.36[137] 0.96[138] 0.80[139] 1.38[140]
21 AKT2 RAC-beta serine/threonine-protein kinase [141] 0.71[142] 0.88[143] 0.84[144] 0.68[145] 0.53[146] 0.76[147]
22 TCIRG1 V-type proton ATPase 116 kDa subunit a isoform 3 [148] -0.21[149] 0.18[150] -0.06[151] 2.15[152] 0.44[153] 0.45[154]
23 KLB Beta-klotho [155] 0.35[156] 0.08[157] 1.36[158] -6.14[159] -6.72[160] 1.17[161]
24 ATP6V1H V-type proton ATPase subunit H [162] -0.57[163] -0.78[164] -1.79[165] 0.45[166] 0.40[167] -0.93[168]
25 KRAS GTPase KRas [169] -0.76[170] -0.89[171] 0.54[172] 0.62[173] 0.34[174] 0.30[175]
26 FGFR3 Fibroblast growth factor receptor 3 [176] 2.48[177] 2.29[178] 2.44[179] -3.47[180] -2.06[181] 0.07[182]
27 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [183] -0.72[184] -0.71[185] 0.21[186] 1.89[187] 1.45[188] 2.63[189]
28 SOS1 Son of sevenless homolog 1 [190] -0.35[191] 1.08[192] 0.41[193] 0.67[194] -0.04[195] 0.16[196]
29 ATP6V0A1 V-type proton ATPase 116 kDa subunit a isoform 1 [197] 0.22[198] 0.00[199] 1.34[200] 0.48[201] 0.29[202] 1.35[203]
30 INSR Insulin receptor [204] 0.21[205] 0.76[206] 2.02[207] -3.26[208] -0.60[209] 3.63[210]
31 ATP6V1C1 V-type proton ATPase subunit C 1 [211] 0.90[212] 1.12[213] 1.13[214] 2.12[215] 1.71[216] 0.94[217]
32 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta [218] 1.62[219] 1.74[220] 2.18[221] 0.53[222] 1.15[223] -0.67[224]
33 PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 [225] 0.13[226] 0.66[227] -0.43[228] 0.63[229] 0.90[230] 0.26[231]
34 MAPK3 Mitogen-activated protein kinase 3 [232] 1.60[233] 1.54[234] 1.41[235] 0.25[236] 0.33[237] -1.42[238]
35 FGF2 Fibroblast growth factor 2 [239] -6.94[240] -6.79[241] -2.81[242] 0.76[243] 2.40[244] -2.04[245]
36 GRB10 Growth factor receptor-bound protein 10 [246] 2.26[247] -0.93[248] 1.28[249] 0.51[250] 1.44[251] 1.57[252]
37 PDPK1 3-phosphoinositide-dependent protein kinase 1 [253] 2.08[254] 3.17[255] 1.71[256] 1.26[257] 1.71[258] 2.13[259]
38 PDE3B cGMP-inhibited 3',5'-cyclic phosphodiesterase B [260] 0.20[261] 1.06[262] 1.14[263] -1.56[264] -1.94[265] 2.50[266]
39 PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 0.96[267] 1.36[268] 1.35[269] 0.87[270] 1.09[271] 0.78[272]
40 IRS1 Insulin receptor substrate 1 [273] 1.84[274] 1.18[275] 2.44[276] 1.53[277] 1.17[278] 1.74[279]
41 IRS2 Insulin receptor substrate 2 [280] -5.90[281] [282] -3.32[283] -0.84[284] 3.04[285] 2.01[286]
42 PIK3R4 Phosphoinositide 3-kinase regulatory subunit 4 [287] 0.91[288] 0.87[289] 1.66[290] 1.49[291] 2.02[292] 2.50[293]
43 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform -0.63[294] 0.90[295] 0.92[296] 0.95[297] 1.21[298] 1.54[299]
44 THEM4 Acyl-coenzyme A thioesterase THEM4 [300] 0.40[301] 0.74[302] 1.11[303] 1.83[304] 1.31[305] 0.71[306]
45 FLT3LG Fms-related tyrosine kinase 3 ligand [307] -2.51[308] -2.52[309] -2.22[310] -2.51[311] -1.37[312] -2.53[313]
46 GAB2 GRB2-associated-binding protein 2 [314] 1.31[315] 1.00[316] 1.07[317] 0.74[318] 0.89[319] 0.17[320]
47 ATP6V0A2 V-type proton ATPase 116 kDa subunit a isoform 2 [321] 1.09[322] 1.81[323] 0.97[324] 1.02[325] 1.61[326] 1.80[327]
48 FGFR2 Fibroblast growth factor receptor 2 [328] -2.76[329] -1.66[330] 2.11[331] 1.28[332] -3.50[333] 3.05[334]
49 FRS2 Fibroblast growth factor receptor substrate 2 [335] 1.04[336] 2.03[337] 2.35[338] 2.73[339] 2.41[340] 2.97[341]
50 ATP6V0D2 V-type proton ATPase subunit d 2 [342] -4.53[343] -4.81[344] -4.99[345] -6.14[346] -3.24[347] -7.21[348]
51 ATP6V1E2 V-type proton ATPase subunit E 2 [349] -2.15[350] -2.72[351] -2.92[352] -2.30[353] -2.33[354] -1.97[355]
52 FGFR1 Fibroblast growth factor receptor 1 [356] 4.33[357] 2.54[358] 4.02[359] 4.88[360] 4.21[361] 1.29[362]
53 GAB1 GRB2-associated-binding protein 1 [363] 1.05[364] 2.04[365] 1.99[366] 1.76[367] 1.68[368] 2.50[369]
54 FGF7 Fibroblast growth factor 7 [370] -9.54[371] -5.95[372] [373] -5.55[374] -1.22[375] -1.83[376]
55 ATP6V1C2 V-type proton ATPase subunit C 2 [377] 0.57[378] 1.16[379] -0.58[380] 0.44[381] -0.46[382] 0.54[383]
56 KL Klotho [384] -6.30[385] [386] [387] -1.57[388] -6.76[389] -0.13[390]
57 FGF5 Fibroblast growth factor 5 [391] -1.24[392] -0.02[393] -0.27[394] 1.31[395] 1.05[396] 2.76[397]
58 FGF1 Fibroblast growth factor 1 [398] -3.01[399] -2.33[400] -6.96[401] 0.41[402] 2.05[403] -0.33[404]
59 FGF19 Fibroblast growth factor 19 [405] -2.31[406] -1.26[407] 5.31[408] 0.65[409] -2.76[410] [411]
60 ATP6V1G2 V-type proton ATPase subunit G 2 [412] -0.47[413] 0.44[414] -0.08[415] 0.16[416] 2.25[417] -0.92[418]
61 ATP6V1B1 V-type proton ATPase subunit B, kidney isoform [419] -1.33[420] 2.04[421] 2.01[422] 0.76[423] -0.75[424] -2.75[425]
62 FLT3 Receptor-type tyrosine-protein kinase FLT3 [426] [427] [428] -4.02[429] -2.97[430] [431] 2.54[432]
63 FGF8 Fibroblast growth factor 8 [433] -3.58[434] -3.34[435] 0.99[436] -2.09[437] [438] 2.32[439]
64 FGF18 Fibroblast growth factor 18 [440] 1.53[441] -2.69[442] -0.69[443] 0.44[444] 1.09[445] 0.21[446]
65 FGF9 Fibroblast growth factor 9 [447] 2.01[448] -1.75[449] [450] 2.61[451] -2.45[452] -0.27[453]
66 ATP6V1G3 V-type proton ATPase subunit G 3 [454] [455] [456] [457] [458] [459] [460]
67 TLR9 Toll-like receptor 9 [461] [462] [463] [464] [465] [466] [467]
68 FGF4 Fibroblast growth factor 4 [468] [469] [470] [471] [472] [473] [474]
69 FGF3 Fibroblast growth factor 3 [475] [476] [477] [478] [479] [480] [481]
70 FGF20 Fibroblast growth factor 20 [482] [483] [484] [485] [486] [487] [488]
71 INS Insulin [489] [490] [491] [492] [493] [494] [495]
72 FGF16 Fibroblast growth factor 16 [496] [497] [498] [499] [500] [501] [502]
73 FGF22 Fibroblast growth factor 22 [503] [504] [505] [506] [507] [508] [509]
74 FGF10 Fibroblast growth factor 10 [510] [511] [512] [513] [514] [515] [516]
75 FGF17 Fibroblast growth factor 17 [517] [518] [519] [520] [521] [522] [523]
76 FGF23 Fibroblast growth factor 23 [524] [525] [526] [527] [528] [529] [530]
77 FGF6 Fibroblast growth factor 6 [531] [532] [533] [534] [535] [536] [537]
78 ATP6V0A4 V-type proton ATPase 116 kDa subunit a isoform 4 [538] [539] [540] [541] [542] [543] [544]
[1]
ref_hepatocyte ATP6V0E1
Mean 93.3
Standard deviation 36
Values 73 82 53 1.4e+02 1.1e+02
[2]
HepG2 ATP6V0E1
Mean 80.9
Standard deviation 11
Values 73 89
[3]
HepG2.C3A ATP6V0E1
Mean 45.4
Standard deviation 9.4
Values 39 52
[4]
HuH.7 ATP6V0E1
Mean 47.8
Standard deviation 3.2
Values 45 48 51
[5]
SNU475 ATP6V0E1
Mean 68.3
Standard deviation 15
Values 79 58
[6]
THLE ATP6V0E1
Mean 56.1
Standard deviation 4.9
Values 53 60
[7]
liver ATP6V0E1
Mean 54.4
Standard deviation 48
Values 1.1e+02 21 72 11
[8]
ref_hepatocyte ATP6V0B
Mean 68.7
Standard deviation 30
Values 49 74 46 1.2e+02 55
[9]
HepG2 ATP6V0B
Mean 52.2
Standard deviation 1.9
Values 51 54
[10]
HepG2.C3A ATP6V0B
Mean 52.9
Standard deviation 0.13
Values 53 53
[11]
HuH.7 ATP6V0B
Mean 34.5
Standard deviation 5.1
Values 31 32 40
[12]
SNU475 ATP6V0B
Mean 38.6
Standard deviation 8.5
Values 33 45
[13]
THLE ATP6V0B
Mean 55.6
Standard deviation 2.1
Values 54 57
[14]
liver ATP6V0B
Mean 59.8
Standard deviation 57
Values 1.2e+02 11 1e+02 11
[15]
ref_hepatocyte ATP6V0C
Mean 54.9
Standard deviation 21
Values 37 35 87 59 57
[16]
HepG2 ATP6V0C
Mean 55.8
Standard deviation 9.9
Values 63 49
[17]
HepG2.C3A ATP6V0C
Mean 36.7
Standard deviation 6.1
Values 41 32
[18]
HuH.7 ATP6V0C
Mean 33.3
Standard deviation 3
Values 36 30 34
[19]
SNU475 ATP6V0C
Mean 27.7
Standard deviation 0.4
Values 27 28
[20]
THLE ATP6V0C
Mean 53.6
Standard deviation 12
Values 45 62
[21]
liver ATP6V0C
Mean 25.6
Standard deviation 27
Values 49 1.8 49 2.3
[22]
ref_hepatocyte ATP6V1G1
Mean 44.4
Standard deviation 23
Values 29 37 84 30 41
[23]
HepG2 ATP6V1G1
Mean 60.5
Standard deviation 9.9
Values 53 68
[24]
HepG2.C3A ATP6V1G1
Mean 57.9
Standard deviation 22
Values 42 74
[25]
HuH.7 ATP6V1G1
Mean 48.2
Standard deviation 5.5
Values 42 50 52
[26]
SNU475 ATP6V1G1
Mean 45.6
Standard deviation 4.8
Values 49 42
[27]
THLE ATP6V1G1
Mean 58.5
Standard deviation 1.9
Values 57 60
[28]
liver ATP6V1G1
Mean 41.8
Standard deviation 30
Values 76 19 58 15
[29]
ref_hepatocyte ATP6V1F
Mean 40.5
Standard deviation 16
Values 36 28 66 43 28
[30]
HepG2 ATP6V1F
Mean 38.2
Standard deviation 1.3
Values 37 39
[31]
HepG2.C3A ATP6V1F
Mean 29.9
Standard deviation 4.9
Values 26 33
[32]
HuH.7 ATP6V1F
Mean 28.9
Standard deviation 6
Values 29 23 35
[33]
SNU475 ATP6V1F
Mean 27.5
Standard deviation 5.5
Values 31 24
[34]
THLE ATP6V1F
Mean 32.4
Standard deviation 1.9
Values 34 31
[35]
liver ATP6V1F
Mean 14.9
Standard deviation 16
Values 32 1.6 24 2.1
[36]
ref_hepatocyte ATP6V1E1
Mean 38.1
Standard deviation 11
Values 39 54 34 39 25
[37]
HepG2 ATP6V1E1
Mean 62.6
Standard deviation 14
Values 53 73
[38]
HepG2.C3A ATP6V1E1
Mean 52.2
Standard deviation 17
Values 40 64
[39]
HuH.7 ATP6V1E1
Mean 56.5
Standard deviation 7
Values 48 60 61
[40]
SNU475 ATP6V1E1
Mean 65
Standard deviation 11
Values 73 57
[41]
THLE ATP6V1E1
Mean 74.7
Standard deviation 0.76
Values 74 75
[42]
liver ATP6V1E1
Mean 17.6
Standard deviation 8.8
Values 28 11 22 9.9
[43]
ref_hepatocyte TRIB3
Mean 31.8
Standard deviation 22
Values 21 25 60 47 5.9
[44]
HepG2 TRIB3
Mean 132
Standard deviation 85
Values 1.9e+02 72
[45]
HepG2.C3A TRIB3
Mean 144
Standard deviation 1.1e+02
Values 2.2e+02 66
[46]
HuH.7 TRIB3
Mean 63.7
Standard deviation 8.9
Values 57 74 61
[47]
SNU475 TRIB3
Mean 14.5
Standard deviation 3.3
Values 12 17
[48]
THLE TRIB3
Mean 23
Standard deviation 5.7
Values 27 19
[49]
liver TRIB3
Mean 33.8
Standard deviation 26
Values 72 16 30 17
[50]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 33 53 10 7.5 7.4
[51]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 58 76
[52]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 68 92
[53]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 86 77 61
[54]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 75 76
[55]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[56]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 60 99 62 80
[57]
ref_hepatocyte ATP6AP1
Mean 21.7
Standard deviation 15
Values 45 16 5.8 24 18
[58]
HepG2 ATP6AP1
Mean 68.6
Standard deviation 6.5
Values 73 64
[59]
HepG2.C3A ATP6AP1
Mean 50.9
Standard deviation 17
Values 63 39
[60]
HuH.7 ATP6AP1
Mean 57
Standard deviation 4.3
Values 55 62 54
[61]
SNU475 ATP6AP1
Mean 37.2
Standard deviation 0.62
Values 38 37
[62]
THLE ATP6AP1
Mean 59
Standard deviation 5.7
Values 55 63
[63]
liver ATP6AP1
Mean 23.1
Standard deviation 17
Values 39 8 37 8.7
[64]
ref_hepatocyte ATP6V0D1
Mean 20.9
Standard deviation 6.8
Values 16 17 17 32 22
[65]
HepG2 ATP6V0D1
Mean 38.3
Standard deviation 7.7
Values 33 44
[66]
HepG2.C3A ATP6V0D1
Mean 24.5
Standard deviation 1.2
Values 24 25
[67]
HuH.7 ATP6V0D1
Mean 30.7
Standard deviation 4.7
Values 35 25 32
[68]
SNU475 ATP6V0D1
Mean 36.9
Standard deviation 5.6
Values 41 33
[69]
THLE ATP6V0D1
Mean 36.6
Standard deviation 7.5
Values 31 42
[70]
liver ATP6V0D1
Mean 30.2
Standard deviation 17
Values 37 15 51 17
[71]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[72]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[73]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[74]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[75]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[76]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[77]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[78]
ref_hepatocyte ATP6V1B2
Mean 17.8
Standard deviation 8.1
Values 20 16 31 12 11
[79]
HepG2 ATP6V1B2
Mean 44.3
Standard deviation 7.3
Values 39 49
[80]
HepG2.C3A ATP6V1B2
Mean 37.8
Standard deviation 6.2
Values 33 42
[81]
HuH.7 ATP6V1B2
Mean 51.3
Standard deviation 1.2
Values 50 51 53
[82]
SNU475 ATP6V1B2
Mean 27.9
Standard deviation 3.7
Values 25 30
[83]
THLE ATP6V1B2
Mean 40.1
Standard deviation 1.5
Values 39 41
[84]
liver ATP6V1B2
Mean 25.5
Standard deviation 3.7
Values 27 27 29 20
[85]
ref_hepatocyte ATP6V1D
Mean 17.8
Standard deviation 6.7
Values 17 26 8.2 22 16
[86]
HepG2 ATP6V1D
Mean 22.9
Standard deviation 6.9
Values 18 28
[87]
HepG2.C3A ATP6V1D
Mean 17.9
Standard deviation 7.9
Values 12 23
[88]
HuH.7 ATP6V1D
Mean 11.6
Standard deviation 0.44
Values 11 11 12
[89]
SNU475 ATP6V1D
Mean 30.6
Standard deviation 2.4
Values 32 29
[90]
THLE ATP6V1D
Mean 45.9
Standard deviation 1.9
Values 45 47
[91]
liver ATP6V1D
Mean 14.1
Standard deviation 9.1
Values 23 7.6 21 5
[92]
ref_hepatocyte SHC1
Mean 16.6
Standard deviation 7.2
Values 5.8 17 19 26 16
[93]
HepG2 SHC1
Mean 82
Standard deviation 0.099
Values 82 82
[94]
HepG2.C3A SHC1
Mean 84.9
Standard deviation 11
Values 77 93
[95]
HuH.7 SHC1
Mean 85.9
Standard deviation 2.4
Values 89 84 85
[96]
SNU475 SHC1
Mean 191
Standard deviation 36
Values 2.2e+02 1.7e+02
[97]
THLE SHC1
Mean 150
Standard deviation 11
Values 1.4e+02 1.6e+02
[98]
liver SHC1
Mean 40.4
Standard deviation 11
Values 37 32 56 37
[99]
ref_hepatocyte ATP6V0E2
Mean 15.9
Standard deviation 13
Values 28 2 2.1 17 30
[100]
HepG2 ATP6V0E2
Mean 53.2
Standard deviation 31
Values 31 75
[101]
HepG2.C3A ATP6V0E2
Mean 59.6
Standard deviation 13
Values 50 69
[102]
HuH.7 ATP6V0E2
Mean 0.354
Standard deviation 0.027
Values 0.39 0.34 0.34
[103]
SNU475 ATP6V0E2
Mean 16.2
Standard deviation 4.2
Values 19 13
[104]
THLE ATP6V0E2
Mean 9.07
Standard deviation 1.2
Values 8.2 10
[105]
liver ATP6V0E2
Mean 25.8
Standard deviation 20
Values 51 8.5 32 11
[106]
ref_hepatocyte FGFR4
Mean 15.1
Standard deviation 12
Values 30 2.5 2.2 18 23
[107]
HepG2 FGFR4
Mean 129
Standard deviation 13
Values 1.2e+02 1.4e+02
[108]
HepG2.C3A FGFR4
Mean 146
Standard deviation 22
Values 1.6e+02 1.3e+02
[109]
HuH.7 FGFR4
Mean 209
Standard deviation 68
Values 2.4e+02 1.3e+02 2.5e+02
[110]
SNU475 FGFR4
Mean 1.47
Standard deviation 0.43
Values 1.2 1.8
[111]
THLE FGFR4
Mean 1.51
Standard deviation 0.45
Values 1.8 1.2
[112]
liver FGFR4
Mean 30.3
Standard deviation 10
Values 43 18 31 29
[113]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[114]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[115]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[116]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[117]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[118]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[119]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[120]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[121]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[122]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[123]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[124]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[125]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[126]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[127]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 14 13 13 6.1 7.4
[128]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 62 93
[129]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 71 81
[130]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 73 60 61
[131]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 77 65
[132]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[133]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 39 68 41 61
[134]
ref_hepatocyte ATP6V1A
Mean 10.7
Standard deviation 7
Values 22 12 3.5 6.7 9
[135]
HepG2 ATP6V1A
Mean 30.4
Standard deviation 10
Values 23 37
[136]
HepG2.C3A ATP6V1A
Mean 33.6
Standard deviation 6.3
Values 29 38
[137]
HuH.7 ATP6V1A
Mean 37.2
Standard deviation 1.5
Values 39 36 37
[138]
SNU475 ATP6V1A
Mean 43.1
Standard deviation 8.2
Values 49 37
[139]
THLE ATP6V1A
Mean 41.4
Standard deviation 4.5
Values 38 45
[140]
liver ATP6V1A
Mean 51
Standard deviation 6
Values 56 52 54 43
[141]
ref_hepatocyte AKT2
Mean 10.6
Standard deviation 2.8
Values 7.2 8.4 11 13 14
[142]
HepG2 AKT2
Mean 45.6
Standard deviation 3.3
Values 48 43
[143]
HepG2.C3A AKT2
Mean 49.1
Standard deviation 8.9
Values 55 43
[144]
HuH.7 AKT2
Mean 51.5
Standard deviation 9.8
Values 59 41 55
[145]
SNU475 AKT2
Mean 35.3
Standard deviation 5.9
Values 39 31
[146]
THLE AKT2
Mean 34.2
Standard deviation 3.5
Values 32 37
[147]
liver AKT2
Mean 33
Standard deviation 9.4
Values 24 36 27 45
[148]
ref_hepatocyte TCIRG1
Mean 9.93
Standard deviation 3.9
Values 6 6.7 9.9 16 11
[149]
HepG2 TCIRG1
Mean 22.6
Standard deviation 5.8
Values 19 27
[150]
HepG2.C3A TCIRG1
Mean 28.4
Standard deviation 9.1
Values 35 22
[151]
HuH.7 TCIRG1
Mean 25.9
Standard deviation 3.4
Values 22 27 29
[152]
SNU475 TCIRG1
Mean 91.6
Standard deviation 20
Values 1.1e+02 77
[153]
THLE TCIRG1
Mean 30.1
Standard deviation 5.9
Values 34 26
[154]
liver TCIRG1
Mean 24.9
Standard deviation 7.7
Values 32 16 21 31
[155]
ref_hepatocyte KLB
Mean 9.92
Standard deviation 12
Values 30 1.9 0.71 6.7 9.9
[156]
HepG2 KLB
Mean 33.1
Standard deviation 23
Values 17 49
[157]
HepG2.C3A KLB
Mean 26.3
Standard deviation 0.12
Values 26 26
[158]
HuH.7 KLB
Mean 68.9
Standard deviation 30
Values 57 1e+02 46
[159]
SNU475 KLB
Mean 0.292
Standard deviation 0.04
Values 0.32 0.26
[160]
THLE KLB
Mean 0.21
Standard deviation 0.004
Values 0.21 0.21
[161]
liver KLB
Mean 41.2
Standard deviation 7.6
Values 52 37 40 36
[162]
ref_hepatocyte ATP6V1H
Mean 9.45
Standard deviation 4.2
Values 11 16 9 6 5.4
[163]
HepG2 ATP6V1H
Mean 16.7
Standard deviation 1.6
Values 16 18
[164]
HepG2.C3A ATP6V1H
Mean 13.8
Standard deviation 1.4
Values 15 13
[165]
HuH.7 ATP6V1H
Mean 7.42
Standard deviation 1.1
Values 6.7 8.7 6.9
[166]
SNU475 ATP6V1H
Mean 26.7
Standard deviation 6.6
Values 31 22
[167]
THLE ATP6V1H
Mean 27.9
Standard deviation 4.7
Values 25 31
[168]
liver ATP6V1H
Mean 9.12
Standard deviation 3.6
Values 13 6.6 11 5.6
[169]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[170]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[171]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[172]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[173]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[174]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[175]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[176]
ref_hepatocyte FGFR3
Mean 7.46
Standard deviation 9.2
Values 23 2.7 0.18 4.6 6.4
[177]
HepG2 FGFR3
Mean 109
Standard deviation 1.1
Values 1.1e+02 1.1e+02
[178]
HepG2.C3A FGFR3
Mean 91.5
Standard deviation 12
Values 1e+02 83
[179]
HuH.7 FGFR3
Mean 110
Standard deviation 12
Values 1.2e+02 97 1.2e+02
[180]
SNU475 FGFR3
Mean 1.4
Standard deviation 0.25
Values 1.6 1.2
[181]
THLE FGFR3
Mean 3.99
Standard deviation 0.31
Values 3.8 4.2
[182]
liver FGFR3
Mean 14.5
Standard deviation 8.7
Values 9.3 18 5.8 25
[183]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.1 7.4 4.2 8.1 14
[184]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 9.8 14
[185]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 9.6 13
[186]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 23 32 15
[187]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 80 35
[188]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[189]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 64 1e+02 32 1.4e+02
[190]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 27 1.9 2.2 1.3 1.5
[191]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 9.4 19
[192]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 39 33
[193]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 22 37 15
[194]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 25 20
[195]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[196]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 13 18 9.3 16
[197]
ref_hepatocyte ATP6V0A1
Mean 6.15
Standard deviation 2.2
Values 4 3.6 7.6 8.3 7.3
[198]
HepG2 ATP6V0A1
Mean 18.9
Standard deviation 0.051
Values 19 19
[199]
HepG2.C3A ATP6V0A1
Mean 15.4
Standard deviation 4.6
Values 19 12
[200]
HuH.7 ATP6V0A1
Mean 42.3
Standard deviation 7.6
Values 44 49 34
[201]
SNU475 ATP6V0A1
Mean 17.9
Standard deviation 0.26
Values 18 18
[202]
THLE ATP6V0A1
Mean 16.8
Standard deviation 0.83
Values 16 17
[203]
liver ATP6V0A1
Mean 28.9
Standard deviation 5.1
Values 29 28 36 23
[204]
ref_hepatocyte INSR
Mean 5.73
Standard deviation 1.4
Values 6.5 5 4.1 5.3 7.7
[205]
HepG2 INSR
Mean 17.4
Standard deviation 4.9
Values 21 14
[206]
HepG2.C3A INSR
Mean 24.3
Standard deviation 6.7
Values 29 20
[207]
HuH.7 INSR
Mean 62.9
Standard deviation 26
Values 58 91 39
[208]
SNU475 INSR
Mean 1.24
Standard deviation 0.29
Values 1.4 1
[209]
THLE INSR
Mean 8.45
Standard deviation 0.32
Values 8.2 8.7
[210]
liver INSR
Mean 131
Standard deviation 15
Values 1.4e+02 1.5e+02 1.1e+02 1.3e+02
[211]
ref_hepatocyte ATP6V1C1
Mean 5.72
Standard deviation 3.8
Values 7.4 12 3.5 3.2 2.9
[212]
HepG2 ATP6V1C1
Mean 28
Standard deviation 11
Values 20 36
[213]
HepG2.C3A ATP6V1C1
Mean 31.1
Standard deviation 8.2
Values 25 37
[214]
HuH.7 ATP6V1C1
Mean 34
Standard deviation 3.2
Values 36 35 30
[215]
SNU475 ATP6V1C1
Mean 51.4
Standard deviation 2.5
Values 50 53
[216]
THLE ATP6V1C1
Mean 41.6
Standard deviation 5.5
Values 38 45
[217]
liver ATP6V1C1
Mean 20.3
Standard deviation 0.37
Values 20 20 21 20
[218]
ref_hepatocyte PIK3R2
Mean 5.25
Standard deviation 3.4
Values 11 3.2 3.1 4.9 3.8
[219]
HepG2 PIK3R2
Mean 42.5
Standard deviation 2.8
Values 44 41
[220]
HepG2.C3A PIK3R2
Mean 44.2
Standard deviation 13
Values 53 35
[221]
HuH.7 PIK3R2
Mean 64.7
Standard deviation 10
Values 75 55 64
[222]
SNU475 PIK3R2
Mean 15.7
Standard deviation 3.3
Values 18 13
[223]
THLE PIK3R2
Mean 26
Standard deviation 2.8
Values 24 28
[224]
liver PIK3R2
Mean 6.1
Standard deviation 1.7
Values 7.6 6 3.8 6.9
[225]
ref_hepatocyte PIK3C3
Mean 4.59
Standard deviation 2.3
Values 8 5.9 2.3 3.8 3
[226]
HepG2 PIK3C3
Mean 13.2
Standard deviation 3.3
Values 11 16
[227]
HepG2.C3A PIK3C3
Mean 18.2
Standard deviation 1.3
Values 17 19
[228]
HuH.7 PIK3C3
Mean 9.26
Standard deviation 1.9
Values 9.1 11 7.5
[229]
SNU475 PIK3C3
Mean 14.7
Standard deviation 3.2
Values 17 12
[230]
THLE PIK3C3
Mean 19.1
Standard deviation 0.92
Values 18 20
[231]
liver PIK3C3
Mean 10.1
Standard deviation 4.2
Values 6.9 15 6.8 11
[232]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 5.1 2.8 3.6 6 3.3
[233]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 37 29
[234]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 39 22
[235]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 34 25 32
[236]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 12 8.5
[237]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[238]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 5 0.81 4.8 0.82
[239]
ref_hepatocyte FGF2
Mean 4.04
Standard deviation 6.5
Values 0.052 15 3.7 0.37 0.73
[240]
HepG2 FGF2
Mean 0.0866
Standard deviation 0.08
Values 0.14 0.03
[241]
HepG2.C3A FGF2
Mean 0.092
Standard deviation 0.0064
Values 0.087 0.097
[242]
HuH.7 FGF2
Mean 1.57
Standard deviation 0.89
Values 0.98 2.6 1.1
[243]
SNU475 FGF2
Mean 14.2
Standard deviation 1.3
Values 13 15
[244]
THLE FGF2
Mean 47.5
Standard deviation 0.66
Values 48 47
[245]
liver FGF2
Mean 1.81
Standard deviation 0.66
Values 1.9 2.5 0.9 2
[246]
ref_hepatocyte GRB10
Mean 3.75
Standard deviation 1.1
Values 2 3.4 4.9 4.1 4.3
[247]
HepG2 GRB10
Mean 47
Standard deviation 17
Values 59 35
[248]
HepG2.C3A GRB10
Mean 4.96
Standard deviation 0.92
Values 5.6 4.3
[249]
HuH.7 GRB10
Mean 24.7
Standard deviation 7
Values 22 33 19
[250]
SNU475 GRB10
Mean 11.1
Standard deviation 1.2
Values 12 10
[251]
THLE GRB10
Mean 22.6
Standard deviation 0.57
Values 22 23
[252]
liver GRB10
Mean 20.5
Standard deviation 8.3
Values 22 21 9.1 29
[253]
ref_hepatocyte PDPK1
Mean 3.54
Standard deviation 2
Values 6.9 3.4 3.6 1.8 2
[254]
HepG2 PDPK1
Mean 39.4
Standard deviation 5.6
Values 35 43
[255]
HepG2.C3A PDPK1
Mean 80.1
Standard deviation 13
Values 89 71
[256]
HuH.7 PDPK1
Mean 31.4
Standard deviation 4.5
Values 35 33 26
[257]
SNU475 PDPK1
Mean 17.6
Standard deviation 0.21
Values 17 18
[258]
THLE PDPK1
Mean 25.9
Standard deviation 4.6
Values 23 29
[259]
liver PDPK1
Mean 28.5
Standard deviation 5.1
Values 34 27 22 31
[260]
ref_hepatocyte PDE3B
Mean 3.29
Standard deviation 1.7
Values 4.3 2 1.3 3.2 5.6
[261]
HepG2 PDE3B
Mean 9.91
Standard deviation 5.3
Values 6.1 14
[262]
HepG2.C3A PDE3B
Mean 17.2
Standard deviation 3.4
Values 15 20
[263]
HuH.7 PDE3B
Mean 19.6
Standard deviation 4.7
Values 20 24 15
[264]
SNU475 PDE3B
Mean 2.32
Standard deviation 0.34
Values 2.6 2.1
[265]
THLE PDE3B
Mean 1.92
Standard deviation 0.37
Values 2.2 1.7
[266]
liver PDE3B
Mean 34.3
Standard deviation 15
Values 28 53 17 40
[267]
ref_hepatocyte PIK3CB
Mean 3.18
Standard deviation 1.5
Values 5.2 4.2 2.6 1.8 2.1
[268]
HepG2 PIK3CB
Mean 16.3
Standard deviation 2.1
Values 15 18
[269]
HepG2.C3A PIK3CB
Mean 20.6
Standard deviation 2.7
Values 23 19
[270]
HuH.7 PIK3CB
Mean 22.1
Standard deviation 2.1
Values 24 23 20
[271]
SNU475 PIK3CB
Mean 12.1
Standard deviation 2.7
Values 14 10
[272]
THLE PIK3CB
Mean 15.1
Standard deviation 0.94
Values 14 16
[273]
liver PIK3CB
Mean 10.1
Standard deviation 3.7
Values 6.4 15 7.9 11
[274]
ref_hepatocyte IRS1
Mean 3.05
Standard deviation 1.4
Values 4.3 1.5 2.7 2.1 4.7
[275]
HepG2 IRS1
Mean 28.7
Standard deviation 8.6
Values 35 23
[276]
HepG2.C3A IRS1
Mean 17.4
Standard deviation 6
Values 22 13
[277]
HuH.7 IRS1
Mean 44.8
Standard deviation 6.6
Values 49 48 37
[278]
SNU475 IRS1
Mean 18.3
Standard deviation 5.2
Values 15 22
[279]
THLE IRS1
Mean 15.3
Standard deviation 0.24
Values 15 15
[280]
liver IRS1
Mean 18.8
Standard deviation 4.8
Values 23 18 12 22
[281]
ref_hepatocyte IRS2
Mean 2.12
Standard deviation 2.3
Values 0.019 0.61 1.4 5.7 2.9
[282]
HepG2 IRS2
Mean 0.0931
Standard deviation 0.071
Values 0.14 0.043
[283]
HepG2.C3A IRS2
Mean 0
Standard deviation 0
Values 0 0
[284]
HuH.7 IRS2
Mean 0.575
Standard deviation 0.68
Values 0.2 1.4 0.17
[285]
SNU475 IRS2
Mean 2.45
Standard deviation 0.45
Values 2.1 2.8
[286]
THLE IRS2
Mean 39
Standard deviation 5.9
Values 35 43
[287]
liver IRS2
Mean 15.7
Standard deviation 9.9
Values 29 11 6.3 17
[288]
ref_hepatocyte PIK3R4
Mean 1.95
Standard deviation 0.81
Values 1.4 1.7 1.2 2.4 3.2
[289]
HepG2 PIK3R4
Mean 9.67
Standard deviation 3.2
Values 7.4 12
[290]
HepG2.C3A PIK3R4
Mean 8.97
Standard deviation 1.7
Values 7.8 10
[291]
HuH.7 PIK3R4
Mean 16.8
Standard deviation 2.8
Values 20 14 16
[292]
SNU475 PIK3R4
Mean 11.4
Standard deviation 0.1
Values 11 11
[293]
THLE PIK3R4
Mean 17.7
Standard deviation 1.3
Values 17 19
[294]
liver PIK3R4
Mean 20.3
Standard deviation 7.7
Values 15 27 12 27
[295]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 2.6 2.3 1.2 0.94
[296]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 2.1 4.3
[297]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 8 9.6
[298]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 10 12 7
[299]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 8.1 6.8
[300]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[301]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 6.1 15 6 13
[302]
ref_hepatocyte THEM4
Mean 1.85
Standard deviation 0.19
Values 1.8 1.7 2.1 2 1.7
[303]
HepG2 THEM4
Mean 6.4
Standard deviation 0.64
Values 5.9 6.9
[304]
HepG2.C3A THEM4
Mean 7.77
Standard deviation 1.9
Values 6.5 9.1
[305]
HuH.7 THEM4
Mean 10.9
Standard deviation 3.9
Values 12 6.4 14
[306]
SNU475 THEM4
Mean 13.7
Standard deviation 1.8
Values 12 15
[307]
THLE THEM4
Mean 10.2
Standard deviation 1.5
Values 9.2 11
[308]
liver THEM4
Mean 5.58
Standard deviation 2.4
Values 8.6 3.8 6.5 3.5
[309]
ref_hepatocyte FLT3LG
Mean 1.73
Standard deviation 1.8
Values 0 0 4.1 1.9 2.7
[310]
HepG2 FLT3LG
Mean 0.799
Standard deviation 0.045
Values 0.83 0.77
[311]
HepG2.C3A FLT3LG
Mean 0.761
Standard deviation 0.27
Values 0.95 0.57
[312]
HuH.7 FLT3LG
Mean 1.01
Standard deviation 0.09
Values 1 1.1 0.92
[313]
SNU475 FLT3LG
Mean 0.629
Standard deviation 0.022
Values 0.64 0.61
[314]
THLE FLT3LG
Mean 1.5
Standard deviation 0.22
Values 1.7 1.3
[315]
liver FLT3LG
Mean 0.55
Standard deviation 0.58
Values 1.3 0.1 0.62 0.15
[316]
ref_hepatocyte GAB2
Mean 1.62
Standard deviation 1.7
Values 1.2 1.9 4.5 0.25 0.31
[317]
HepG2 GAB2
Mean 10.6
Standard deviation 4.9
Values 14 7.1
[318]
HepG2.C3A GAB2
Mean 8.12
Standard deviation 3.2
Values 10 5.9
[319]
HuH.7 GAB2
Mean 9.24
Standard deviation 2.5
Values 9.6 12 6.6
[320]
SNU475 GAB2
Mean 5.63
Standard deviation 0.73
Values 6.1 5.1
[321]
THLE GAB2
Mean 6.7
Standard deviation 0.57
Values 7.1 6.3
[322]
liver GAB2
Mean 3.35
Standard deviation 1.3
Values 2.8 4.2 1.8 4.6
[323]
ref_hepatocyte ATP6V0A2
Mean 1.62
Standard deviation 0.49
Values 2.3 1.8 1.7 1.2 1.1
[324]
HepG2 ATP6V0A2
Mean 9.05
Standard deviation 0.76
Values 8.5 9.6
[325]
HepG2.C3A ATP6V0A2
Mean 14.3
Standard deviation 0.32
Values 14 14
[326]
HuH.7 ATP6V0A2
Mean 8.59
Standard deviation 0.54
Values 8.9 8 8.9
[327]
SNU475 ATP6V0A2
Mean 6.82
Standard deviation 1.7
Values 5.6 8
[328]
THLE ATP6V0A2
Mean 11
Standard deviation 1.4
Values 10 12
[329]
liver ATP6V0A2
Mean 10.4
Standard deviation 4.3
Values 5.1 15 9 13
[330]
ref_hepatocyte FGFR2
Mean 1.34
Standard deviation 1.4
Values 0.47 0.46 0.084 2.4 3.2
[331]
HepG2 FGFR2
Mean 0.519
Standard deviation 0.3
Values 0.3 0.73
[332]
HepG2.C3A FGFR2
Mean 1.07
Standard deviation 0.3
Values 0.86 1.3
[333]
HuH.7 FGFR2
Mean 15.7
Standard deviation 0.71
Values 16 15 16
[334]
SNU475 FGFR2
Mean 6.74
Standard deviation 6.4
Values 11 2.2
[335]
THLE FGFR2
Mean 0.263
Standard deviation 0.0039
Values 0.27 0.26
[336]
liver FGFR2
Mean 20.4
Standard deviation 8
Values 18 19 13 32
[337]
ref_hepatocyte FRS2
Mean 1.15
Standard deviation 0.48
Values 1.3 1.9 0.69 0.74 1.2
[338]
HepG2 FRS2
Mean 6.18
Standard deviation 3
Values 4 8.3
[339]
HepG2.C3A FRS2
Mean 11.7
Standard deviation 4
Values 8.9 15
[340]
HuH.7 FRS2
Mean 15.9
Standard deviation 4.9
Values 16 21 11
[341]
SNU475 FRS2
Mean 15.7
Standard deviation 0.35
Values 16 15
[342]
THLE FRS2
Mean 13.6
Standard deviation 0.96
Values 14 13
[343]
liver FRS2
Mean 16.5
Standard deviation 3.3
Values 18 20 13 15
[344]
ref_hepatocyte ATP6V0D2
Mean 1.07
Standard deviation 2.1
Values 0.047 0.35 4.9 0 0.089
[345]
HepG2 ATP6V0D2
Mean 0.122
Standard deviation 0.039
Values 0.15 0.094
[346]
HepG2.C3A ATP6V0D2
Mean 0.0964
Standard deviation 0.015
Values 0.11 0.086
[347]
HuH.7 ATP6V0D2
Mean 0.0918
Standard deviation 0.14
Values 0 0.26 0.019
[348]
SNU475 ATP6V0D2
Mean 0.0317
Standard deviation 0.0054
Values 0.028 0.035
[349]
THLE ATP6V0D2
Mean 0.253
Standard deviation 0.048
Values 0.22 0.29
[350]
liver ATP6V0D2
Mean 0.0133
Standard deviation 0.011
Values 0 0.014 0.026 0.013
[351]
ref_hepatocyte ATP6V1E2
Mean 0.846
Standard deviation 1
Values 0.061 2.6 0.71 0.43 0.41
[352]
HepG2 ATP6V1E2
Mean 0.5
Standard deviation 0.16
Values 0.61 0.39
[353]
HepG2.C3A ATP6V1E2
Mean 0.322
Standard deviation 0.14
Values 0.42 0.23
[354]
HuH.7 ATP6V1E2
Mean 0.303
Standard deviation 0.028
Values 0.27 0.32 0.32
[355]
SNU475 ATP6V1E2
Mean 0.357
Standard deviation 0.039
Values 0.38 0.33
[356]
THLE ATP6V1E2
Mean 0.376
Standard deviation 0.088
Values 0.44 0.31
[357]
liver ATP6V1E2
Mean 0.399
Standard deviation 0.096
Values 0.38 0.51 0.28 0.42
[358]
ref_hepatocyte FGFR1
Mean 0.81
Standard deviation 0.63
Values 1.2 0.49 1.6 0.06 0.62
[359]
HepG2 FGFR1
Mean 42.7
Standard deviation 4
Values 40 46
[360]
HepG2.C3A FGFR1
Mean 11.8
Standard deviation 3.5
Values 9.3 14
[361]
HuH.7 FGFR1
Mean 35.6
Standard deviation 13
Values 43 20 43
[362]
SNU475 FGFR1
Mean 49.5
Standard deviation 1.4
Values 50 49
[363]
THLE FGFR1
Mean 33.4
Standard deviation 3.3
Values 36 31
[364]
liver FGFR1
Mean 3.64
Standard deviation 0.67
Values 3 4.2 3.2 4.3
[365]
ref_hepatocyte GAB1
Mean 0.787
Standard deviation 0.67
Values 2 0.61 0.33 0.38 0.66
[366]
HepG2 GAB1
Mean 4.28
Standard deviation 2.2
Values 2.8 5.8
[367]
HepG2.C3A GAB1
Mean 8.12
Standard deviation 2.3
Values 6.5 9.8
[368]
HuH.7 GAB1
Mean 8.48
Standard deviation 1.4
Values 10 8.1 7.3
[369]
SNU475 GAB1
Mean 5.52
Standard deviation 1.6
Values 6.6 4.4
[370]
THLE GAB1
Mean 5.62
Standard deviation 0.39
Values 5.9 5.3
[371]
liver GAB1
Mean 8.2
Standard deviation 2.5
Values 7.1 10 5.3 10
[372]
ref_hepatocyte FGF7
Mean 0.61
Standard deviation 0.64
Values 0 0.3 0.46 0.6 1.7
[373]
HepG2 FGF7
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[374]
HepG2.C3A FGF7
Mean 0.0248
Standard deviation 0.02
Values 0.039 0.011
[375]
HuH.7 FGF7
Mean 0
Standard deviation 0
Values 0 0 0
[376]
SNU475 FGF7
Mean 0.027
Standard deviation 0.012
Values 0.019 0.035
[377]
THLE FGF7
Mean 0.584
Standard deviation 0.1
Values 0.66 0.51
[378]
liver FGF7
Mean 0.317
Standard deviation 0.15
Values 0.28 0.31 0.51 0.16
[379]
ref_hepatocyte ATP6V1C2
Mean 0.264
Standard deviation 0.21
Values 0.27 0.53 0 0.14 0.39
[380]
HepG2 ATP6V1C2
Mean 1.03
Standard deviation 0.54
Values 1.4 0.64
[381]
HepG2.C3A ATP6V1C2
Mean 1.48
Standard deviation 0.32
Values 1.3 1.7
[382]
HuH.7 ATP6V1C2
Mean 0.481
Standard deviation 0.048
Values 0.43 0.5 0.52
[383]
SNU475 ATP6V1C2
Mean 0.742
Standard deviation 0.2
Values 0.89 0.6
[384]
THLE ATP6V1C2
Mean 0.43
Standard deviation 0.039
Values 0.4 0.46
[385]
liver ATP6V1C2
Mean 0.706
Standard deviation 0.21
Values 0.45 0.64 0.8 0.94
[386]
ref_hepatocyte KL
Mean 0.258
Standard deviation 0.29
Values 0 0 0.4 0.2 0.69
[387]
HepG2 KL
Mean 0.00858
Standard deviation 0.012
Values 0 0.017
[388]
HepG2.C3A KL
Mean 0
Standard deviation 0
Values 0 0
[389]
HuH.7 KL
Mean 0
Standard deviation 0
Values 0 0 0
[390]
SNU475 KL
Mean 0.181
Standard deviation 0.026
Values 0.2 0.16
[391]
THLE KL
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[392]
liver KL
Mean 0.436
Standard deviation 0.32
Values 0.38 0.31 0.15 0.9
[393]
ref_hepatocyte FGF5
Mean 0.241
Standard deviation 0.27
Values 0.042 0.036 0.09 0.64 0.4
[394]
HepG2 FGF5
Mean 0.268
Standard deviation 0.022
Values 0.25 0.28
[395]
HepG2.C3A FGF5
Mean 0.596
Standard deviation 0.024
Values 0.61 0.58
[396]
HuH.7 FGF5
Mean 0.543
Standard deviation 0.15
Values 0.62 0.65 0.37
[397]
SNU475 FGF5
Mean 1.24
Standard deviation 0.35
Values 0.99 1.5
[398]
THLE FGF5
Mean 1.11
Standard deviation 0.17
Values 0.99 1.2
[399]
liver FGF5
Mean 3.01
Standard deviation 1.5
Values 2.3 4.5 1.2 4.1
[400]
ref_hepatocyte FGF1
Mean 0.126
Standard deviation 0.27
Values 0 0.6 0 0 0.024
[401]
HepG2 FGF1
Mean 0.0408
Standard deviation 0.04
Values 0.069 0.013
[402]
HepG2.C3A FGF1
Mean 0.0628
Standard deviation 0.048
Values 0.029 0.097
[403]
HuH.7 FGF1
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[404]
SNU475 FGF1
Mean 0.346
Standard deviation 0.077
Values 0.29 0.4
[405]
THLE FGF1
Mean 1.16
Standard deviation 0.44
Values 0.85 1.5
[406]
liver FGF1
Mean 0.184
Standard deviation 0.042
Values 0.14 0.21 0.15 0.23
[407]
ref_hepatocyte FGF19
Mean 0.122
Standard deviation 0.27
Values 0 0 0.61 0 0
[408]
HepG2 FGF19
Mean 0.0644
Standard deviation 0.0062
Values 0.069 0.06
[409]
HepG2.C3A FGF19
Mean 0.128
Standard deviation 0.0016
Values 0.13 0.13
[410]
HuH.7 FGF19
Mean 13.1
Standard deviation 3.4
Values 11 17 12
[411]
SNU475 FGF19
Mean 0.397
Standard deviation 0.15
Values 0.51 0.29
[412]
THLE FGF19
Mean 0.0402
Standard deviation 0.027
Values 0.059 0.021
[413]
liver FGF19
Mean 0
Standard deviation 0
Values 0 0 0 0
[414]
ref_hepatocyte ATP6V1G2
Mean 0.118
Standard deviation 0.17
Values 0 0 0 0.2 0.39
[415]
HepG2 ATP6V1G2
Mean 0.223
Standard deviation 0.073
Values 0.28 0.17
[416]
HepG2.C3A ATP6V1G2
Mean 0.401
Standard deviation 0.066
Values 0.45 0.35
[417]
HuH.7 ATP6V1G2
Mean 0.303
Standard deviation 0.08
Values 0.32 0.37 0.22
[418]
SNU475 ATP6V1G2
Mean 0.273
Standard deviation 0.021
Values 0.29 0.26
[419]
THLE ATP6V1G2
Mean 1.25
Standard deviation 0.23
Values 1.4 1.1
[420]
liver ATP6V1G2
Mean 0.115
Standard deviation 0.052
Values 0.19 0.11 0.077 0.079
[421]
ref_hepatocyte ATP6V1B1
Mean 0.0852
Standard deviation 0.19
Values 0.43 0 0 0 0
[422]
HepG2 ATP6V1B1
Mean 0.0887
Standard deviation 0.0042
Values 0.092 0.086
[423]
HepG2.C3A ATP6V1B1
Mean 0.88
Standard deviation 0.5
Values 1.2 0.53
[424]
HuH.7 ATP6V1B1
Mean 0.928
Standard deviation 0.24
Values 0.65 1.1 1.1
[425]
SNU475 ATP6V1B1
Mean 0.3
Standard deviation 0.17
Values 0.42 0.18
[426]
THLE ATP6V1B1
Mean 0.113
Standard deviation 0.024
Values 0.13 0.096
[427]
liver ATP6V1B1
Mean 0.0233
Standard deviation 0.022
Values 0 0.029 0.051 0.013
[428]
ref_hepatocyte FLT3
Mean 0.0374
Standard deviation 0.084
Values 0 0 0 0 0.19
[429]
HepG2 FLT3
Mean 0
Standard deviation 0
Values 0 0
[430]
HepG2.C3A FLT3
Mean 0
Standard deviation 0
Values 0 0
[431]
HuH.7 FLT3
Mean 0.00625
Standard deviation 0.011
Values 0 0 0.019
[432]
SNU475 FLT3
Mean 0.00992
Standard deviation 0.0075
Values 0.0046 0.015
[433]
THLE FLT3
Mean 0
Standard deviation 0
Values 0 0
[434]
liver FLT3
Mean 0.402
Standard deviation 0.15
Values 0.21 0.44 0.39 0.57
[435]
ref_hepatocyte FGF8
Mean 0.0195
Standard deviation 0.044
Values 0 0 0 0 0.098
[436]
HepG2 FGF8
Mean 0.00429
Standard deviation 0.0061
Values 0 0.0086
[437]
HepG2.C3A FGF8
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[438]
HuH.7 FGF8
Mean 0.105
Standard deviation 0.073
Values 0.19 0.051 0.075
[439]
SNU475 FGF8
Mean 0.00949
Standard deviation 0.0063
Values 0.014 0.0051
[440]
THLE FGF8
Mean 0
Standard deviation 0
Values 0 0
[441]
liver FGF8
Mean 0.18
Standard deviation 0.14
Values 0.047 0.34 0.077 0.25
[442]
ref_hepatocyte FGF18
Mean 0.0138
Standard deviation 0.031
Values 0 0 0 0.069 0
[443]
HepG2 FGF18
Mean 0.105
Standard deviation 0.039
Values 0.13 0.077
[444]
HepG2.C3A FGF18
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[445]
HuH.7 FGF18
Mean 0.0232
Standard deviation 0.02
Values 0 0.032 0.037
[446]
SNU475 FGF18
Mean 0.0388
Standard deviation 0.0024
Values 0.037 0.041
[447]
THLE FGF18
Mean 0.0657
Standard deviation 0.033
Values 0.089 0.043
[448]
liver FGF18
Mean 0.0294
Standard deviation 0.0072
Values 0.024 0.029 0.026 0.04
[449]
ref_hepatocyte FGF9
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[450]
HepG2 FGF9
Mean 0.0687
Standard deviation 9.1e-05
Values 0.069 0.069
[451]
HepG2.C3A FGF9
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[452]
HuH.7 FGF9
Mean 0
Standard deviation 0
Values 0 0 0
[453]
SNU475 FGF9
Mean 0.0822
Standard deviation 0.08
Values 0.14 0.025
[454]
THLE FGF9
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[455]
liver FGF9
Mean 0.00993
Standard deviation 0.02
Values 0 0 0 0.04
[456]
ref_hepatocyte ATP6V1G3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[457]
HepG2 ATP6V1G3
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[458]
HepG2.C3A ATP6V1G3
Mean 0
Standard deviation 0
Values 0 0
[459]
HuH.7 ATP6V1G3
Mean 0
Standard deviation 0
Values 0 0 0
[460]
SNU475 ATP6V1G3
Mean 0.362
Standard deviation 0.032
Values 0.38 0.34
[461]
THLE ATP6V1G3
Mean 0
Standard deviation 0
Values 0 0
[462]
liver ATP6V1G3
Mean 0.00588
Standard deviation 0.012
Values 0.024 0 0 0
[463]
ref_hepatocyte TLR9
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[464]
HepG2 TLR9
Mean 0.0229
Standard deviation 0.032
Values 0.046 0
[465]
HepG2.C3A TLR9
Mean 0.197
Standard deviation 0.2
Values 0.34 0.054
[466]
HuH.7 TLR9
Mean 1.11
Standard deviation 1.2
Values 0.44 2.5 0.37
[467]
SNU475 TLR9
Mean 0.0454
Standard deviation 0.021
Values 0.06 0.03
[468]
THLE TLR9
Mean 0.22
Standard deviation 0.12
Values 0.3 0.14
[469]
liver TLR9
Mean 0.227
Standard deviation 0.11
Values 0.12 0.23 0.18 0.38
[470]
ref_hepatocyte FGF4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[471]
HepG2 FGF4
Mean 0
Standard deviation 0
Values 0 0
[472]
HepG2.C3A FGF4
Mean 0
Standard deviation 0
Values 0 0
[473]
HuH.7 FGF4
Mean 0
Standard deviation 0
Values 0 0 0
[474]
SNU475 FGF4
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[475]
THLE FGF4
Mean 0
Standard deviation 0
Values 0 0
[476]
liver FGF4
Mean 0
Standard deviation 0
Values 0 0 0 0
[477]
ref_hepatocyte FGF3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[478]
HepG2 FGF3
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[479]
HepG2.C3A FGF3
Mean 0
Standard deviation 0
Values 0 0
[480]
HuH.7 FGF3
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[481]
SNU475 FGF3
Mean 0.00717
Standard deviation 0.003
Values 0.0093 0.0051
[482]
THLE FGF3
Mean 0
Standard deviation 0
Values 0 0
[483]
liver FGF3
Mean 0
Standard deviation 0
Values 0 0 0 0
[484]
ref_hepatocyte FGF20
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[485]
HepG2 FGF20
Mean 0.0115
Standard deviation 0.016
Values 0.023 0
[486]
HepG2.C3A FGF20
Mean 0
Standard deviation 0
Values 0 0
[487]
HuH.7 FGF20
Mean 0
Standard deviation 0
Values 0 0 0
[488]
SNU475 FGF20
Mean 0.00485
Standard deviation 0.0003
Values 0.0046 0.0051
[489]
THLE FGF20
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[490]
liver FGF20
Mean 0.0118
Standard deviation 0.024
Values 0.047 0 0 0
[491]
ref_hepatocyte INS
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[492]
HepG2 INS
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[493]
HepG2.C3A INS
Mean 0
Standard deviation 0
Values 0 0
[494]
HuH.7 INS
Mean 0
Standard deviation 0
Values 0 0 0
[495]
SNU475 INS
Mean 0
Standard deviation 0
Values 0 0
[496]
THLE INS
Mean 0
Standard deviation 0
Values 0 0
[497]
liver INS
Mean 0.0838
Standard deviation 0.13
Values 0 0.057 0 0.28
[498]
ref_hepatocyte FGF16
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[499]
HepG2 FGF16
Mean 0
Standard deviation 0
Values 0 0
[500]
HepG2.C3A FGF16
Mean 0
Standard deviation 0
Values 0 0
[501]
HuH.7 FGF16
Mean 0
Standard deviation 0
Values 0 0 0
[502]
SNU475 FGF16
Mean 0
Standard deviation 0
Values 0 0
[503]
THLE FGF16
Mean 0
Standard deviation 0
Values 0 0
[504]
liver FGF16
Mean 0.0118
Standard deviation 0.024
Values 0.047 0 0 0
[505]
ref_hepatocyte FGF22
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[506]
HepG2 FGF22
Mean 0.01
Standard deviation 0.002
Values 0.011 0.0086
[507]
HepG2.C3A FGF22
Mean 0
Standard deviation 0
Values 0 0
[508]
HuH.7 FGF22
Mean 0.00625
Standard deviation 0.011
Values 0 0 0.019
[509]
SNU475 FGF22
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[510]
THLE FGF22
Mean 0
Standard deviation 0
Values 0 0
[511]
liver FGF22
Mean 0
Standard deviation 0
Values 0 0 0 0
[512]
ref_hepatocyte FGF10
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[513]
HepG2 FGF10
Mean 0
Standard deviation 0
Values 0 0
[514]
HepG2.C3A FGF10
Mean 0
Standard deviation 0
Values 0 0
[515]
HuH.7 FGF10
Mean 0
Standard deviation 0
Values 0 0 0
[516]
SNU475 FGF10
Mean 0
Standard deviation 0
Values 0 0
[517]
THLE FGF10
Mean 0
Standard deviation 0
Values 0 0
[518]
liver FGF10
Mean 0.0234
Standard deviation 0.038
Values 0 0.014 0 0.079
[519]
ref_hepatocyte FGF17
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[520]
HepG2 FGF17
Mean 0.398
Standard deviation 0.15
Values 0.5 0.29
[521]
HepG2.C3A FGF17
Mean 1.23
Standard deviation 1.1
Values 2 0.46
[522]
HuH.7 FGF17
Mean 0.183
Standard deviation 0.2
Values 0.074 0.41 0.066
[523]
SNU475 FGF17
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[524]
THLE FGF17
Mean 0.0228
Standard deviation 0.0096
Values 0.03 0.016
[525]
liver FGF17
Mean 0.00588
Standard deviation 0.012
Values 0.024 0 0 0
[526]
ref_hepatocyte FGF23
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[527]
HepG2 FGF23
Mean 0
Standard deviation 0
Values 0 0
[528]
HepG2.C3A FGF23
Mean 0
Standard deviation 0
Values 0 0
[529]
HuH.7 FGF23
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[530]
SNU475 FGF23
Mean 0
Standard deviation 0
Values 0 0
[531]
THLE FGF23
Mean 0
Standard deviation 0
Values 0 0
[532]
liver FGF23
Mean 0.68
Standard deviation 0.31
Values 0.59 0.67 1.1 0.36
[533]
ref_hepatocyte FGF6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[534]
HepG2 FGF6
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[535]
HepG2.C3A FGF6
Mean 0
Standard deviation 0
Values 0 0
[536]
HuH.7 FGF6
Mean 0
Standard deviation 0
Values 0 0 0
[537]
SNU475 FGF6
Mean 0
Standard deviation 0
Values 0 0
[538]
THLE FGF6
Mean 0
Standard deviation 0
Values 0 0
[539]
liver FGF6
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[540]
ref_hepatocyte ATP6V0A4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[541]
HepG2 ATP6V0A4
Mean 1.16
Standard deviation 1.5
Values 2.2 0.086
[542]
HepG2.C3A ATP6V0A4
Mean 0.0667
Standard deviation 0.012
Values 0.058 0.075
[543]
HuH.7 ATP6V0A4
Mean 0
Standard deviation 0
Values 0 0 0
[544]
SNU475 ATP6V0A4
Mean 0.761
Standard deviation 0.014
Values 0.75 0.77
[545]
THLE ATP6V0A4
Mean 0.189
Standard deviation 0.049
Values 0.15 0.22
[546]
liver ATP6V0A4
Mean 0
Standard deviation 0
Values 0 0 0 0