REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GPC3 Glypican-3 [1] 0.75[2] 1.05[3] 0.59[4] -7.64[5] -7.21[6] -8.51[7]
2 SDC1 Syndecan-1 [8] -1.93[9] -2.51[10] -1.26[11] -2.10[12] -4.18[13] 0.51[14]
3 SDC4 Syndecan-4 [15] -1.13[16] -1.57[17] -1.89[18] -1.49[19] 0.28[20] -0.38[21]
4 SDC2 Syndecan-2 [22] -1.02[23] -0.20[24] 0.34[25] 0.07[26] -2.92[27] 0.35[28]
5 GPC1 Glypican-1 [29] -0.93[30] -4.39[31] -7.50[32] 2.72[33] 1.72[34] -0.80[35]
6 B3GAT3 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 [36] -1.55[37] -1.30[38] -0.79[39] -0.12[40] 0.53[41] -1.05[42]
7 B4GALT7 Beta-1,4-galactosyltransferase 7 [43] -1.95[44] -1.93[45] -0.68[46] -0.82[47] -0.42[48] -1.26[49]
8 AGRN Agrin [50] 2.72[51] 2.03[52] 2.42[53] 3.80[54] 3.06[55] 0.80[56]
9 B3GALT6 Beta-1,3-galactosyltransferase 6 [57] -1.12[58] -0.27[59] 0.00[60] 0.18[61] 0.01[62] -1.25[63]
10 XYLT2 Xylosyltransferase 2 [64] 0.00[65] -0.34[66] 0.94[67] 1.36[68] 1.97[69] 0.22[70]
11 GPC6 Glypican-6 [71] 1.17[72] 0.23[73] 1.72[74] 4.20[75] 2.51[76] 2.98[77]
12 SDC3 Syndecan-3 [78] 1.37[79] -4.98[80] -0.07[81] 3.39[82] 3.89[83] 2.47[84]
13 DCN Decorin [85] -7.77[86] -9.62[87] -5.84[88] 1.80[89] 6.18[90] 5.42[91]
14 BGN Biglycan [92] 0.53[93] -4.83[94] -6.18[95] 2.04[96] -0.27[97] 5.07[98]
15 B3GAT1 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 [99] -9.65[100] -9.28[101] [102] -8.57[103] -0.77[104] 0.75[105]
16 HSPG2 Basement membrane-specific heparan sulfate proteoglycan core protein 6.18[106] 4.30[107] 5.60[108] 6.31[109] 6.69[110] 6.09[111]
17 VCAN Versican core protein [112] 3.31[113] -1.97[114] 3.05[115] 1.75[116] 6.27[117] 3.55[118]
18 GPC4 Glypican-4 [119] -2.44[120] -6.62[121] -1.94[122] 5.74[123] -1.81[124] 0.66[125]
19 CSPG5 Chondroitin sulfate proteoglycan 5 [126] -2.65[127] -5.49[128] 1.28[129] 1.41[130] -0.48[131] -2.50[132]
20 GPC5 Glypican-5 [133] -4.62[134] -6.06[135] -0.77[136] -2.98[137] -2.25[138] 3.30[139]
21 GPC2 Glypican-2 [140] 1.47[141] 0.79[142] 3.72[143] 3.60[144] 2.66[145] -3.34[146]
22 XYLT1 Xylosyltransferase 1 [147] 0.72[148] [149] [150] 1.34[151] 1.86[152] 5.62[153]
23 NCAN Neurocan core protein [154] 0.27[155] -2.64[156] 0.60[157] -3.30[158] -0.22[159] -1.11[160]
24 CSPG4 Chondroitin sulfate proteoglycan 4 [161] 2.10[162] 0.99[163] 3.70[164] 7.42[165] 8.30[166] 5.52[167]
25 BCAN Brevican core protein [168] 6.77[169] 6.84[170] 5.97[171] 7.62[172] 5.78[173] 2.43[174]
26 B3GAT2 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 [175] [176] [177] [178] [179] [180] [181]
[1]
ref_hepatocyte GPC3
Mean 126
Standard deviation 2.8e+02
Values 6.3e+02 0.054 0.022 0.2 0.45
[2]
HepG2 GPC3
Mean 1.26e+03
Standard deviation 9.2
Values 1.3e+03 1.3e+03
[3]
HepG2.C3A GPC3
Mean 1.5e+03
Standard deviation 6.5e+02
Values 2e+03 1e+03
[4]
HuH.7 GPC3
Mean 561
Standard deviation 1.5e+02
Values 4.3e+02 7.2e+02 5.4e+02
[5]
SNU475 GPC3
Mean 0.967
Standard deviation 0.21
Values 1.1 0.82
[6]
THLE GPC3
Mean 1.25
Standard deviation 0.31
Values 1.5 1
[7]
liver GPC3
Mean 0.594
Standard deviation 0.31
Values 0.47 0.46 1.1 0.4
[8]
ref_hepatocyte SDC1
Mean 90.9
Standard deviation 70
Values 30 69 33 1.3e+02 1.9e+02
[9]
HepG2 SDC1
Mean 143
Standard deviation 14
Values 1.5e+02 1.3e+02
[10]
HepG2.C3A SDC1
Mean 92.1
Standard deviation 9.8
Values 85 99
[11]
HuH.7 SDC1
Mean 113
Standard deviation 31
Values 1.3e+02 77 1.3e+02
[12]
SNU475 SDC1
Mean 32.6
Standard deviation 5
Values 36 29
[13]
THLE SDC1
Mean 7.4
Standard deviation 0.31
Values 7.6 7.2
[14]
liver SDC1
Mean 222
Standard deviation 69
Values 1.8e+02 2.1e+02 3.2e+02 1.7e+02
[15]
ref_hepatocyte SDC4
Mean 75.2
Standard deviation 11
Values 84 85 60 78 68
[16]
HepG2 SDC4
Mean 206
Standard deviation 1.1e+02
Values 2.8e+02 1.3e+02
[17]
HepG2.C3A SDC4
Mean 146
Standard deviation 40
Values 1.7e+02 1.2e+02
[18]
HuH.7 SDC4
Mean 59.9
Standard deviation 26
Values 47 90 43
[19]
SNU475 SDC4
Mean 41
Standard deviation 1.5
Values 42 40
[20]
THLE SDC4
Mean 134
Standard deviation 15
Values 1.2e+02 1.4e+02
[21]
liver SDC4
Mean 99.2
Standard deviation 32
Values 1.1e+02 74 1.4e+02 74
[22]
ref_hepatocyte SDC2
Mean 42.2
Standard deviation 32
Values 57 12 12 42 87
[23]
HepG2 SDC2
Mean 124
Standard deviation 1.5
Values 1.2e+02 1.3e+02
[24]
HepG2.C3A SDC2
Mean 212
Standard deviation 41
Values 2.4e+02 1.8e+02
[25]
HuH.7 SDC2
Mean 158
Standard deviation 56
Values 1.2e+02 2.2e+02 1.3e+02
[26]
SNU475 SDC2
Mean 68
Standard deviation 21
Values 83 53
[27]
THLE SDC2
Mean 8.21
Standard deviation 1.9
Values 9.6 6.9
[28]
liver SDC2
Mean 92.5
Standard deviation 51
Values 1.7e+02 61 82 60
[29]
ref_hepatocyte GPC1
Mean 11.5
Standard deviation 7.6
Values 1.4 21 16 9.6 8.7
[30]
HepG2 GPC1
Mean 35.9
Standard deviation 11
Values 44 28
[31]
HepG2.C3A GPC1
Mean 3.16
Standard deviation 0.57
Values 2.8 3.6
[32]
HuH.7 GPC1
Mean 0.188
Standard deviation 0.13
Values 0.3 0.23 0.037
[33]
SNU475 GPC1
Mean 115
Standard deviation 39
Values 1.4e+02 88
[34]
THLE GPC1
Mean 55.5
Standard deviation 8.3
Values 50 61
[35]
liver GPC1
Mean 11.3
Standard deviation 3.4
Values 7.6 13 15 9.6
[36]
ref_hepatocyte B3GAT3
Mean 11.3
Standard deviation 6.4
Values 3.2 9.5 11 21 12
[37]
HepG2 B3GAT3
Mean 23
Standard deviation 3.8
Values 26 20
[38]
HepG2.C3A B3GAT3
Mean 26.4
Standard deviation 4.5
Values 30 23
[39]
HuH.7 B3GAT3
Mean 19.3
Standard deviation 7.4
Values 20 11 26
[40]
SNU475 B3GAT3
Mean 15.9
Standard deviation 3.3
Values 18 14
[41]
THLE B3GAT3
Mean 23.9
Standard deviation 0.35
Values 24 24
[42]
liver B3GAT3
Mean 9.32
Standard deviation 7.7
Values 14 2.8 18 2.6
[43]
ref_hepatocyte B4GALT7
Mean 9.13
Standard deviation 4.3
Values 3.2 6.7 14 12 9.9
[44]
HepG2 B4GALT7
Mean 14.1
Standard deviation 0.49
Values 14 14
[45]
HepG2.C3A B4GALT7
Mean 13.9
Standard deviation 2.5
Values 16 12
[46]
HuH.7 B4GALT7
Mean 17
Standard deviation 4.6
Values 18 12 21
[47]
SNU475 B4GALT7
Mean 7.94
Standard deviation 1.7
Values 9.2 6.7
[48]
THLE B4GALT7
Mean 10
Standard deviation 0.3
Values 9.8 10
[49]
liver B4GALT7
Mean 6.54
Standard deviation 2.2
Values 5.5 5.1 9.8 5.7
[50]
ref_hepatocyte AGRN
Mean 5.08
Standard deviation 2.6
Values 4.9 9.5 3.2 4.4 3.4
[51]
HepG2 AGRN
Mean 201
Standard deviation 74
Values 2.5e+02 1.5e+02
[52]
HepG2.C3A AGRN
Mean 120
Standard deviation 34
Values 1.4e+02 95
[53]
HuH.7 AGRN
Mean 80.8
Standard deviation 15
Values 96 66 80
[54]
SNU475 AGRN
Mean 108
Standard deviation 64
Values 1.5e+02 63
[55]
THLE AGRN
Mean 62.4
Standard deviation 19
Values 49 76
[56]
liver AGRN
Mean 15.2
Standard deviation 13
Values 4 26 3.2 28
[57]
ref_hepatocyte B3GALT6
Mean 4.63
Standard deviation 1.2
Values 5 2.9 5.1 6.1 4
[58]
HepG2 B3GALT6
Mean 12.7
Standard deviation 2.1
Values 14 11
[59]
HepG2.C3A B3GALT6
Mean 22.1
Standard deviation 4.7
Values 25 19
[60]
HuH.7 B3GALT6
Mean 13.8
Standard deviation 3.8
Values 15 9.6 17
[61]
SNU475 B3GALT6
Mean 8.03
Standard deviation 1.7
Values 9.2 6.8
[62]
THLE B3GALT6
Mean 6.89
Standard deviation 1.4
Values 5.9 7.9
[63]
liver B3GALT6
Mean 3.34
Standard deviation 1.6
Values 1.6 4.6 2.4 4.8
[64]
ref_hepatocyte XYLT2
Mean 3.26
Standard deviation 0.95
Values 4.7 2.9 3.6 2.8 2.2
[65]
HepG2 XYLT2
Mean 19.5
Standard deviation 5.3
Values 23 16
[66]
HepG2.C3A XYLT2
Mean 14.8
Standard deviation 2.8
Values 17 13
[67]
HuH.7 XYLT2
Mean 18.6
Standard deviation 2.1
Values 21 17 18
[68]
SNU475 XYLT2
Mean 12.8
Standard deviation 0.031
Values 13 13
[69]
THLE XYLT2
Mean 18.8
Standard deviation 1.5
Values 18 20
[70]
liver XYLT2
Mean 6.5
Standard deviation 0.92
Values 7.3 5.9 5.5 7.3
[71]
ref_hepatocyte GPC6
Mean 2.38
Standard deviation 1.5
Values 3.3 1.3 0.41 2.8 4
[72]
HepG2 GPC6
Mean 32
Standard deviation 10
Values 25 39
[73]
HepG2.C3A GPC6
Mean 16.1
Standard deviation 1.8
Values 15 17
[74]
HuH.7 GPC6
Mean 23.3
Standard deviation 7.4
Values 21 31 17
[75]
SNU475 GPC6
Mean 67.1
Standard deviation 28
Values 87 47
[76]
THLE GPC6
Mean 19.9
Standard deviation 5
Values 16 23
[77]
liver GPC6
Mean 32.3
Standard deviation 8.7
Values 38 30 21 40
[78]
ref_hepatocyte SDC3
Mean 1.04
Standard deviation 0.71
Values 0.11 0.84 0.73 1.7 1.8
[79]
HepG2 SDC3
Mean 16
Standard deviation 2.6
Values 18 14
[80]
HepG2.C3A SDC3
Mean 0.19
Standard deviation 0.035
Values 0.17 0.21
[81]
HuH.7 SDC3
Mean 2.95
Standard deviation 1.2
Values 4 1.7 3.2
[82]
SNU475 SDC3
Mean 16.7
Standard deviation 0.42
Values 17 16
[83]
THLE SDC3
Mean 22.7
Standard deviation 0.49
Values 22 23
[84]
liver SDC3
Mean 9.95
Standard deviation 2.5
Values 9.5 13 7.1 10
[85]
ref_hepatocyte DCN
Mean 0.734
Standard deviation 1.2
Values 0 0 0.17 0.72 2.8
[86]
HepG2 DCN
Mean 0.02
Standard deviation 0.0041
Values 0.023 0.017
[87]
HepG2.C3A DCN
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[88]
HuH.7 DCN
Mean 0.038
Standard deviation 0.019
Values 0.057 0.019 0.037
[89]
SNU475 DCN
Mean 3.92
Standard deviation 0.29
Values 3.7 4.1
[90]
THLE DCN
Mean 78.6
Standard deviation 48
Values 1.1e+02 44
[91]
liver DCN
Mean 54.1
Standard deviation 15
Values 60 51 70 35
[92]
ref_hepatocyte BGN
Mean 0.625
Standard deviation 0.62
Values 0.052 0 0.61 1.4 1
[93]
HepG2 BGN
Mean 5.39
Standard deviation 1.6
Values 6.5 4.3
[94]
HepG2.C3A BGN
Mean 0.127
Standard deviation 0.013
Values 0.14 0.12
[95]
HuH.7 BGN
Mean 0.0256
Standard deviation 0.029
Values 0.057 0.019 0
[96]
SNU475 BGN
Mean 3.94
Standard deviation 1.9
Values 2.6 5.3
[97]
THLE BGN
Mean 0.764
Standard deviation 0.37
Values 1 0.51
[98]
liver BGN
Mean 36.2
Standard deviation 29
Values 65 9.5 57 13
[99]
ref_hepatocyte B3GAT1
Mean 0.577
Standard deviation 0.51
Values 0 0.23 0.44 1 1.2
[100]
HepG2 B3GAT1
Mean 0.00429
Standard deviation 0.0061
Values 0 0.0086
[101]
HepG2.C3A B3GAT1
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[102]
HuH.7 B3GAT1
Mean 0
Standard deviation 0
Values 0 0 0
[103]
SNU475 B3GAT1
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[104]
THLE B3GAT1
Mean 0.499
Standard deviation 0.089
Values 0.56 0.44
[105]
liver B3GAT1
Mean 1.67
Standard deviation 1.8
Values 0.19 3.8 2.5 0.13
[106]
ref_hepatocyte HSPG2
Mean 0.417
Standard deviation 0.41
Values 1.1 0.16 0.49 0.16 0.18
[107]
HepG2 HSPG2
Mean 181
Standard deviation 62
Values 2.3e+02 1.4e+02
[108]
HepG2.C3A HSPG2
Mean 47.5
Standard deviation 2.4
Values 46 49
[109]
HuH.7 HSPG2
Mean 59.8
Standard deviation 39
Values 1e+02 34 40
[110]
SNU475 HSPG2
Mean 50.5
Standard deviation 35
Values 75 26
[111]
THLE HSPG2
Mean 63.4
Standard deviation 18
Values 50 76
[112]
liver HSPG2
Mean 49
Standard deviation 38
Values 14 64 22 96
[113]
ref_hepatocyte VCAN
Mean 0.409
Standard deviation 0.32
Values 0.014 0.17 0.6 0.47 0.8
[114]
HepG2 VCAN
Mean 24.2
Standard deviation 5.2
Values 21 28
[115]
HepG2.C3A VCAN
Mean 0.601
Standard deviation 0.27
Values 0.41 0.79
[116]
HuH.7 VCAN
Mean 10
Standard deviation 9.3
Values 6.1 21 3.4
[117]
SNU475 VCAN
Mean 2.11
Standard deviation 1.7
Values 0.9 3.3
[118]
THLE VCAN
Mean 46.4
Standard deviation 11
Values 39 54
[119]
liver VCAN
Mean 8.26
Standard deviation 6.7
Values 4.5 8.5 2.4 18
[120]
ref_hepatocyte GPC4
Mean 0.349
Standard deviation 0.51
Values 0.13 0.065 1.2 0 0.33
[121]
HepG2 GPC4
Mean 0.383
Standard deviation 0.074
Values 0.44 0.33
[122]
HepG2.C3A GPC4
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[123]
HuH.7 GPC4
Mean 0.269
Standard deviation 0.25
Values 0.18 0.55 0.075
[124]
SNU475 GPC4
Mean 28.5
Standard deviation 18
Values 41 16
[125]
THLE GPC4
Mean 0.147
Standard deviation 0.048
Values 0.11 0.18
[126]
liver GPC4
Mean 0.949
Standard deviation 0.44
Values 0.71 1.1 0.51 1.5
[127]
ref_hepatocyte CSPG5
Mean 0.152
Standard deviation 0.19
Values 0 0.34 0 0.39 0.033
[128]
HepG2 CSPG5
Mean 0.145
Standard deviation 0.022
Values 0.16 0.13
[129]
HepG2.C3A CSPG5
Mean 0.0194
Standard deviation 0.027
Values 0.039 0
[130]
HuH.7 CSPG5
Mean 1.09
Standard deviation 0.56
Values 1.3 0.46 1.5
[131]
SNU475 CSPG5
Mean 0.62
Standard deviation 0.32
Values 0.39 0.85
[132]
THLE CSPG5
Mean 0.16
Standard deviation 0.016
Values 0.17 0.15
[133]
liver CSPG5
Mean 0.0462
Standard deviation 0.032
Values 0.024 0.043 0.026 0.093
[134]
ref_hepatocyte GPC5
Mean 0.0619
Standard deviation 0.066
Values 0 0 0.14 0.052 0.11
[135]
HepG2 GPC5
Mean 0.015
Standard deviation 0.0031
Values 0.017 0.013
[136]
HepG2.C3A GPC5
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[137]
HuH.7 GPC5
Mean 0.107
Standard deviation 0.094
Values 0.082 0.21 0.028
[138]
SNU475 GPC5
Mean 0.012
Standard deviation 0.0027
Values 0.014 0.01
[139]
THLE GPC5
Mean 0.0192
Standard deviation 0.01
Values 0.012 0.027
[140]
liver GPC5
Mean 1.04
Standard deviation 0.64
Values 2 0.83 0.72 0.64
[141]
ref_hepatocyte GPC2
Mean 0.0542
Standard deviation 0.044
Values 0.094 0 0.019 0.06 0.098
[142]
HepG2 GPC2
Mean 0.9
Standard deviation 0.41
Values 1.2 0.61
[143]
HepG2.C3A GPC2
Mean 0.541
Standard deviation 0.0087
Values 0.53 0.55
[144]
HuH.7 GPC2
Mean 2.11
Standard deviation 0.72
Values 2.1 1.4 2.8
[145]
SNU475 GPC2
Mean 1.01
Standard deviation 0.087
Values 0.95 1.1
[146]
THLE GPC2
Mean 0.506
Standard deviation 0.038
Values 0.53 0.48
[147]
liver GPC2
Mean 0.00918
Standard deviation 0.011
Values 0.024 0 0 0.013
[148]
ref_hepatocyte XYLT1
Mean 0.0168
Standard deviation 0.025
Values 0 0 0.027 0 0.057
[149]
HepG2 XYLT1
Mean 0.166
Standard deviation 0.19
Values 0.3 0.034
[150]
HepG2.C3A XYLT1
Mean 0
Standard deviation 0
Values 0 0
[151]
HuH.7 XYLT1
Mean 0
Standard deviation 0
Values 0 0 0
[152]
SNU475 XYLT1
Mean 0.0654
Standard deviation 0.00068
Values 0.065 0.066
[153]
THLE XYLT1
Mean 0.0899
Standard deviation 0.069
Values 0.041 0.14
[154]
liver XYLT1
Mean 1.43
Standard deviation 1.4
Values 0.31 1.3 0.64 3.5
[155]
ref_hepatocyte NCAN
Mean 0.0163
Standard deviation 0.036
Values 0 0 0.082 0 0
[156]
HepG2 NCAN
Mean 0.117
Standard deviation 0.12
Values 0.2 0.034
[157]
HepG2.C3A NCAN
Mean 0.0151
Standard deviation 0.0062
Values 0.019 0.011
[158]
HuH.7 NCAN
Mean 0.0731
Standard deviation 0.043
Values 0.041 0.12 0.056
[159]
SNU475 NCAN
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[160]
THLE NCAN
Mean 0.0207
Standard deviation 0.029
Values 0.041 0
[161]
liver NCAN
Mean 0.013
Standard deviation 0.015
Values 0.024 0.029 0 0
[162]
ref_hepatocyte CSPG4
Mean 0.0131
Standard deviation 0.018
Values 0.014 0 0.043 0 0.0081
[163]
HepG2 CSPG4
Mean 0.338
Standard deviation 0.09
Values 0.4 0.27
[164]
HepG2.C3A CSPG4
Mean 0.151
Standard deviation 0.062
Values 0.19 0.11
[165]
HuH.7 CSPG4
Mean 0.505
Standard deviation 0.16
Values 0.57 0.62 0.33
[166]
SNU475 CSPG4
Mean 3.45
Standard deviation 0.17
Values 3.6 3.3
[167]
THLE CSPG4
Mean 6.12
Standard deviation 2.4
Values 4.4 7.8
[168]
liver CSPG4
Mean 1.04
Standard deviation 1.2
Values 0.16 1.3 0.1 2.5
[169]
ref_hepatocyte BCAN
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[170]
HepG2 BCAN
Mean 4.23
Standard deviation 3.5
Values 6.7 1.8
[171]
HepG2.C3A BCAN
Mean 4.29
Standard deviation 0.91
Values 4.9 3.6
[172]
HuH.7 BCAN
Mean 1.21
Standard deviation 0.35
Values 1.3 1.5 0.83
[173]
SNU475 BCAN
Mean 1.96
Standard deviation 0.26
Values 2.1 1.8
[174]
THLE BCAN
Mean 0.527
Standard deviation 0.083
Values 0.59 0.47
[175]
liver BCAN
Mean 0.0604
Standard deviation 0.033
Values 0.071 0.029 0.1 0.04
[176]
ref_hepatocyte B3GAT2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[177]
HepG2 B3GAT2
Mean 0
Standard deviation 0
Values 0 0
[178]
HepG2.C3A B3GAT2
Mean 0
Standard deviation 0
Values 0 0
[179]
HuH.7 B3GAT2
Mean 0
Standard deviation 0
Values 0 0 0
[180]
SNU475 B3GAT2
Mean 0
Standard deviation 0
Values 0 0
[181]
THLE B3GAT2
Mean 0
Standard deviation 0
Values 0 0
[182]
liver B3GAT2
Mean 0.00993
Standard deviation 0.02
Values 0 0 0 0.04