REACTOME_SIGNALING_BY_FGFR2_IIIA_TM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 POLR2L DNA-directed RNA polymerases I, II, and III subunit RPABC5 [1] -2.07[2] -2.09[3] -2.46[4] -1.40[5] -1.92[6] -0.66[7]
2 POLR2J DNA-directed RNA polymerase II subunit RPB11-a [8] -2.77[9] -2.49[10] -2.34[11] -2.63[12] -2.76[13] -2.41[14]
3 POLR2E DNA-directed RNA polymerases I, II, and III subunit RPABC1 [15] 1.01[16] 0.96[17] 0.91[18] 0.23[19] 0.64[20] 1.15[21]
4 POLR2H DNA-directed RNA polymerases I, II, and III subunit RPABC3 [22] -1.17[23] -0.55[24] -0.72[25] -1.88[26] -1.64[27] -1.28[28]
5 POLR2F DNA-directed RNA polymerases I, II, and III subunit RPABC2 [29] -0.87[30] -0.63[31] -1.59[32] -1.81[33] -1.52[34] -0.39[35]
6 POLR2K DNA-directed RNA polymerases I, II, and III subunit RPABC4 [36] -1.19[37] -0.34[38] -0.59[39] -0.16[40] -0.70[41] -0.60[42]
7 POLR2G DNA-directed RNA polymerase II subunit RPB7 [43] -0.76[44] -0.49[45] -1.13[46] -0.36[47] -0.94[48] -1.15[49]
8 GTF2F2 General transcription factor IIF subunit 2 [50] -1.54[51] -0.92[52] -0.74[53] -1.33[54] -1.55[55] -1.91[56]
9 NCBP2 Nuclear cap-binding protein subunit 2 [57] -0.07[58] 0.39[59] 0.33[60] -0.08[61] -0.27[62] -0.66[63]
10 POLR2C DNA-directed RNA polymerase II subunit RPB3 [64] 1.22[65] 1.33[66] 0.68[67] 0.56[68] 0.33[69] 0.22[70]
11 POLR2I DNA-directed RNA polymerase II subunit RPB9 [71] -1.18[72] -1.06[73] -1.28[74] -1.48[75] -1.85[76] -0.36[77]
12 GTF2F1 General transcription factor IIF subunit 1 [78] 0.79[79] 0.38[80] 1.71[81] 0.40[82] 0.46[83] -0.59[84]
13 POLR2B DNA-directed RNA polymerase II subunit RPB2 [85] 1.62[86] 2.00[87] 1.79[88] 1.90[89] 2.15[90] 1.62[91]
14 POLR2D DNA-directed RNA polymerase II subunit RPB4 [92] 0.65[93] 0.78[94] -0.07[95] 0.39[96] 0.16[97] 0.24[98]
15 POLR2A DNA-directed RNA polymerase II subunit RPB1 [99] 3.13[100] 1.66[101] 2.52[102] 2.95[103] 2.89[104] 2.47[105]
16 NCBP1 Nuclear cap-binding protein subunit 1 [106] 1.66[107] 1.87[108] 1.55[109] 2.55[110] 2.64[111] 1.91[112]
17 FGF2 Fibroblast growth factor 2 [113] -6.29[114] -6.04[115] -2.03[116] 1.73[117] 2.86[118] -0.99[119]
18 FGFR2 Fibroblast growth factor receptor 2 [120] -2.11[121] -0.91[122] 2.89[123] 2.25[124] -3.04[125] 4.10[126]
19 FGF1 Fibroblast growth factor 1 [127] -2.36[128] -1.58[129] -6.18[130] 1.38[131] 2.51[132] 0.71[133]
[1]
ref_hepatocyte POLR2L
Mean 67.8
Standard deviation 41
Values 12 45 1.2e+02 88 75
[2]
HepG2 POLR2L
Mean 26.9
Standard deviation 9.4
Values 20 34
[3]
HepG2.C3A POLR2L
Mean 23.8
Standard deviation 11
Values 16 31
[4]
HuH.7 POLR2L
Mean 19.4
Standard deviation 11
Values 20 8.1 30
[5]
SNU475 POLR2L
Mean 27.1
Standard deviation 4.2
Values 30 24
[6]
THLE POLR2L
Mean 29.2
Standard deviation 3.5
Values 27 32
[7]
liver POLR2L
Mean 38.1
Standard deviation 40
Values 74 3.8 71 3.9
[8]
ref_hepatocyte POLR2J
Mean 37.5
Standard deviation 21
Values 11 18 56 56 47
[9]
HepG2 POLR2J
Mean 9.2
Standard deviation 0.083
Values 9.3 9.1
[10]
HepG2.C3A POLR2J
Mean 10
Standard deviation 2.4
Values 8.3 12
[11]
HuH.7 POLR2J
Mean 11.7
Standard deviation 3.3
Values 12 8.1 15
[12]
SNU475 POLR2J
Mean 6.41
Standard deviation 0.42
Values 6.7 6.1
[13]
THLE POLR2J
Mean 9.03
Standard deviation 0.31
Values 9.2 8.8
[14]
liver POLR2J
Mean 6.28
Standard deviation 6.7
Values 14 0.84 9.4 0.7
[15]
ref_hepatocyte POLR2E
Mean 27.9
Standard deviation 6.6
Values 19 23 30 33 35
[16]
HepG2 POLR2E
Mean 93.8
Standard deviation 2.1
Values 95 92
[17]
HepG2.C3A POLR2E
Mean 81.1
Standard deviation 3.3
Values 83 79
[18]
HuH.7 POLR2E
Mean 82.6
Standard deviation 22
Values 97 58 93
[19]
SNU475 POLR2E
Mean 34.6
Standard deviation 3.7
Values 37 32
[20]
THLE POLR2E
Mean 70.5
Standard deviation 6.2
Values 66 75
[21]
liver POLR2E
Mean 55.3
Standard deviation 38
Values 84 18 92 27
[22]
ref_hepatocyte POLR2H
Mean 27.5
Standard deviation 6.8
Values 24 25 29 38 21
[23]
HepG2 POLR2H
Mean 20.4
Standard deviation 2.4
Values 19 22
[24]
HepG2.C3A POLR2H
Mean 28
Standard deviation 0.23
Values 28 28
[25]
HuH.7 POLR2H
Mean 26.4
Standard deviation 6.6
Values 24 21 34
[26]
SNU475 POLR2H
Mean 7.91
Standard deviation 0.017
Values 7.9 7.9
[27]
THLE POLR2H
Mean 14.3
Standard deviation 0.26
Values 14 14
[28]
liver POLR2H
Mean 10.1
Standard deviation 4.7
Values 14 6.5 14 5.4
[29]
ref_hepatocyte POLR2F
Mean 24.8
Standard deviation 6.1
Values 23 34 19 28 21
[30]
HepG2 POLR2F
Mean 22.8
Standard deviation 0.98
Values 22 23
[31]
HepG2.C3A POLR2F
Mean 23.9
Standard deviation 6.4
Values 19 28
[32]
HuH.7 POLR2F
Mean 13
Standard deviation 3.5
Values 13 9.7 17
[33]
SNU475 POLR2F
Mean 7.49
Standard deviation 0.4
Values 7.2 7.8
[34]
THLE POLR2F
Mean 14
Standard deviation 3
Values 12 16
[35]
liver POLR2F
Mean 16.8
Standard deviation 16
Values 36 4.2 24 2.4
[36]
ref_hepatocyte POLR2K
Mean 24.4
Standard deviation 5.5
Values 20 27 17 29 29
[37]
HepG2 POLR2K
Mean 17.9
Standard deviation 2.7
Values 16 20
[38]
HepG2.C3A POLR2K
Mean 28.8
Standard deviation 10
Values 22 36
[39]
HuH.7 POLR2K
Mean 25.7
Standard deviation 7.6
Values 25 19 34
[40]
SNU475 POLR2K
Mean 23.1
Standard deviation 3.2
Values 25 21
[41]
THLE POLR2K
Mean 24.3
Standard deviation 2.2
Values 23 26
[42]
liver POLR2K
Mean 14.3
Standard deviation 12
Values 26 5.3 23 3.1
[43]
ref_hepatocyte POLR2G
Mean 24.2
Standard deviation 8.6
Values 18 28 13 34 28
[44]
HepG2 POLR2G
Mean 23.8
Standard deviation 0.4
Values 24 24
[45]
HepG2.C3A POLR2G
Mean 25.8
Standard deviation 7.7
Values 20 31
[46]
HuH.7 POLR2G
Mean 17.4
Standard deviation 8.7
Values 15 10 27
[47]
SNU475 POLR2G
Mean 19.9
Standard deviation 4.4
Values 23 17
[48]
THLE POLR2G
Mean 20.5
Standard deviation 2.2
Values 19 22
[49]
liver POLR2G
Mean 9.68
Standard deviation 8.6
Values 14 2.8 20 2.3
[50]
ref_hepatocyte GTF2F2
Mean 22.4
Standard deviation 20
Values 31 55 12 8.4 5.6
[51]
HepG2 GTF2F2
Mean 12.8
Standard deviation 1.9
Values 11 14
[52]
HepG2.C3A GTF2F2
Mean 17.7
Standard deviation 0.02
Values 18 18
[53]
HuH.7 GTF2F2
Mean 21.2
Standard deviation 3.4
Values 23 17 23
[54]
SNU475 GTF2F2
Mean 9.42
Standard deviation 1.8
Values 8.2 11
[55]
THLE GTF2F2
Mean 12.4
Standard deviation 1.8
Values 11 14
[56]
liver GTF2F2
Mean 5.3
Standard deviation 2.8
Values 8.4 3.5 6.8 2.5
[57]
ref_hepatocyte NCBP2
Mean 21.2
Standard deviation 13
Values 41 29 15 11 11
[58]
HepG2 NCBP2
Mean 33.8
Standard deviation 0.93
Values 33 34
[59]
HepG2.C3A NCBP2
Mean 41.6
Standard deviation 4.5
Values 45 38
[60]
HuH.7 NCBP2
Mean 42.1
Standard deviation 12
Values 45 29 53
[61]
SNU475 NCBP2
Mean 21.2
Standard deviation 3.1
Values 23 19
[62]
THLE NCBP2
Mean 28.5
Standard deviation 2.5
Values 27 30
[63]
liver NCBP2
Mean 11.9
Standard deviation 5.9
Values 15 7.7 19 6.3
[64]
ref_hepatocyte POLR2C
Mean 17.6
Standard deviation 4.3
Values 15 13 24 20 17
[65]
HepG2 POLR2C
Mean 68.6
Standard deviation 8
Values 63 74
[66]
HepG2.C3A POLR2C
Mean 66
Standard deviation 11
Values 58 74
[67]
HuH.7 POLR2C
Mean 44.6
Standard deviation 6.4
Values 45 38 51
[68]
SNU475 POLR2C
Mean 27.4
Standard deviation 1.2
Values 28 27
[69]
THLE POLR2C
Mean 36.1
Standard deviation 1
Values 37 35
[70]
liver POLR2C
Mean 18.3
Standard deviation 4.9
Values 20 16 24 13
[71]
ref_hepatocyte POLR2I
Mean 14.8
Standard deviation 8.2
Values 6.7 5.5 20 18 24
[72]
HepG2 POLR2I
Mean 10.9
Standard deviation 0.95
Values 12 10
[73]
HepG2.C3A POLR2I
Mean 10.6
Standard deviation 0.63
Values 10 11
[74]
HuH.7 POLR2I
Mean 9.58
Standard deviation 4.2
Values 9.6 5.4 14
[75]
SNU475 POLR2I
Mean 5.6
Standard deviation 1.6
Values 4.4 6.8
[76]
THLE POLR2I
Mean 6.67
Standard deviation 0.3
Values 6.9 6.5
[77]
liver POLR2I
Mean 10.3
Standard deviation 10
Values 20 2.1 19 0.83
[78]
ref_hepatocyte GTF2F1
Mean 14.3
Standard deviation 3.7
Values 14 17 18 14 8.5
[79]
HepG2 GTF2F1
Mean 41.2
Standard deviation 6.7
Values 46 36
[80]
HepG2.C3A GTF2F1
Mean 27.7
Standard deviation 6.3
Values 32 23
[81]
HuH.7 GTF2F1
Mean 73.5
Standard deviation 6.5
Values 81 71 68
[82]
SNU475 GTF2F1
Mean 19.9
Standard deviation 2.9
Values 18 22
[83]
THLE GTF2F1
Mean 31.8
Standard deviation 5
Values 28 35
[84]
liver GTF2F1
Mean 8.41
Standard deviation 2.9
Values 9.6 6.7 12 5.4
[85]
ref_hepatocyte POLR2B
Mean 11.1
Standard deviation 5.1
Values 14 19 8.6 7.8 6.5
[86]
HepG2 POLR2B
Mean 56.9
Standard deviation 17
Values 45 69
[87]
HepG2.C3A POLR2B
Mean 66.2
Standard deviation 18
Values 54 79
[88]
HuH.7 POLR2B
Mean 60.6
Standard deviation 7.6
Values 65 52 65
[89]
SNU475 POLR2B
Mean 43.8
Standard deviation 2.4
Values 42 46
[90]
THLE POLR2B
Mean 79.8
Standard deviation 7.8
Values 74 85
[91]
liver POLR2B
Mean 30.4
Standard deviation 5.1
Values 27 37 26 33
[92]
ref_hepatocyte POLR2D
Mean 10.5
Standard deviation 5.2
Values 17 13 12 6.5 4.1
[93]
HepG2 POLR2D
Mean 27.7
Standard deviation 1.1
Values 27 29
[94]
HepG2.C3A POLR2D
Mean 27
Standard deviation 7.8
Values 22 33
[95]
HuH.7 POLR2D
Mean 15.9
Standard deviation 5.1
Values 19 10 19
[96]
SNU475 POLR2D
Mean 14.6
Standard deviation 0.75
Values 14 15
[97]
THLE POLR2D
Mean 19.2
Standard deviation 4.2
Values 16 22
[98]
liver POLR2D
Mean 11
Standard deviation 2.8
Values 13 8.6 14 8.7
[99]
ref_hepatocyte POLR2A
Mean 7.79
Standard deviation 4.5
Values 9.5 5.3 15 4.9 4.5
[100]
HepG2 POLR2A
Mean 114
Standard deviation 23
Values 98 1.3e+02
[101]
HepG2.C3A POLR2A
Mean 37
Standard deviation 6.8
Values 32 42
[102]
HuH.7 POLR2A
Mean 70.7
Standard deviation 33
Values 1.1e+02 40 66
[103]
SNU475 POLR2A
Mean 63.7
Standard deviation 8.3
Values 70 58
[104]
THLE POLR2A
Mean 93.7
Standard deviation 26
Values 75 1.1e+02
[105]
liver POLR2A
Mean 38.4
Standard deviation 3.6
Values 41 33 40 40
[106]
ref_hepatocyte NCBP1
Mean 5.21
Standard deviation 2.7
Values 8.1 8.2 2.7 3.9 3.2
[107]
HepG2 NCBP1
Mean 27.5
Standard deviation 12
Values 19 36
[108]
HepG2.C3A NCBP1
Mean 28.5
Standard deviation 8.5
Values 23 35
[109]
HuH.7 NCBP1
Mean 24.1
Standard deviation 6.3
Values 30 17 25
[110]
SNU475 NCBP1
Mean 32.3
Standard deviation 2.4
Values 31 34
[111]
THLE NCBP1
Mean 52.8
Standard deviation 5
Values 49 56
[112]
liver NCBP1
Mean 17.5
Standard deviation 5.4
Values 11 24 15 19
[113]
ref_hepatocyte FGF2
Mean 4.04
Standard deviation 6.5
Values 0.052 15 3.7 0.37 0.73
[114]
HepG2 FGF2
Mean 0.0866
Standard deviation 0.08
Values 0.14 0.03
[115]
HepG2.C3A FGF2
Mean 0.092
Standard deviation 0.0064
Values 0.087 0.097
[116]
HuH.7 FGF2
Mean 1.57
Standard deviation 0.89
Values 0.98 2.6 1.1
[117]
SNU475 FGF2
Mean 14.2
Standard deviation 1.3
Values 13 15
[118]
THLE FGF2
Mean 47.5
Standard deviation 0.66
Values 48 47
[119]
liver FGF2
Mean 1.81
Standard deviation 0.66
Values 1.9 2.5 0.9 2
[120]
ref_hepatocyte FGFR2
Mean 1.34
Standard deviation 1.4
Values 0.47 0.46 0.084 2.4 3.2
[121]
HepG2 FGFR2
Mean 0.519
Standard deviation 0.3
Values 0.3 0.73
[122]
HepG2.C3A FGFR2
Mean 1.07
Standard deviation 0.3
Values 0.86 1.3
[123]
HuH.7 FGFR2
Mean 15.7
Standard deviation 0.71
Values 16 15 16
[124]
SNU475 FGFR2
Mean 6.74
Standard deviation 6.4
Values 11 2.2
[125]
THLE FGFR2
Mean 0.263
Standard deviation 0.0039
Values 0.27 0.26
[126]
liver FGFR2
Mean 20.4
Standard deviation 8
Values 18 19 13 32
[127]
ref_hepatocyte FGF1
Mean 0.126
Standard deviation 0.27
Values 0 0.6 0 0 0.024
[128]
HepG2 FGF1
Mean 0.0408
Standard deviation 0.04
Values 0.069 0.013
[129]
HepG2.C3A FGF1
Mean 0.0628
Standard deviation 0.048
Values 0.029 0.097
[130]
HuH.7 FGF1
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[131]
SNU475 FGF1
Mean 0.346
Standard deviation 0.077
Values 0.29 0.4
[132]
THLE FGF1
Mean 1.16
Standard deviation 0.44
Values 0.85 1.5
[133]
liver FGF1
Mean 0.184
Standard deviation 0.042
Values 0.14 0.21 0.15 0.23