REACTOME_SIGNALING_BY_FGFR1 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.95[2] -1.14[3] -1.17[4] -1.56[5] -1.10[6] -0.57[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] -0.51[16] -0.39[17] -0.80[18] -0.70[19] -0.72[20] -0.11[21]
4 UBA52 Ubiquitin-60S ribosomal protein L40 [22] 1.92[23] 1.84[24] 2.71[25] 0.69[26] 1.51[27] 0.65[28]
5 PPP2R1A Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform 2.04[29] 1.88[30] 1.63[31] 2.43[32] 1.76[33] 1.46[34]
6 PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 1.52[35] 1.62[36] 0.81[37] 1.97[38] 2.08[39] 1.21[40]
7 PPP2CB Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform 0.85[41] 0.52[42] 0.43[43] 0.77[44] 0.66[45] 0.32[46]
8 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [47] 1.69[48] 2.13[49] 1.91[50] 2.11[51] 2.74[52] 2.57[53]
9 GRB2 Growth factor receptor-bound protein 2 [54] 2.44[55] 2.29[56] 2.23[57] 1.78[58] 1.69[59] 1.61[60]
10 SHC1 SHC-transforming protein 1 [61] 2.41[62] 2.64[63] 2.54[64] 3.88[65] 3.36[66] 2.09[67]
11 NRAS GTPase NRas [68] 1.87[69] 2.32[70] 2.55[71] 2.22[72] 1.79[73] 1.06[74]
12 HRAS GTPase HRas [75] 0.24[76] -0.46[77] -1.42[78] 0.28[79] 0.06[80] -1.35[81]
13 MAPK1 Mitogen-activated protein kinase 1 [82] 2.95[83] 3.11[84] 2.76[85] 3.07[86] 2.72[87] 3.09[88]
14 KRAS GTPase KRas [89] 0.73[90] 0.72[91] 2.14[92] 2.03[93] 1.68[94] 1.99[95]
15 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [96] 0.77[97] 0.90[98] 1.82[99] 3.29[100] 2.79[101] 4.31[102]
16 FGFRL1 Fibroblast growth factor receptor-like 1 [103] 2.42[104] 2.59[105] 1.85[106] 1.45[107] 1.71[108] 2.13[109]
17 SOS1 Son of sevenless homolog 1 [110] 1.14[111] 2.69[112] 2.02[113] 2.07[114] 1.30[115] 1.85[116]
18 FLRT3 Leucine-rich repeat transmembrane protein FLRT3 [117] -0.38[118] -6.27[119] 3.31[120] 1.45[121] -0.69[122] 1.48[123]
19 MAPK3 Mitogen-activated protein kinase 3 [124] 3.09[125] 3.15[126] 3.02[127] 1.65[128] 1.67[129] 0.27[130]
20 FGF2 Fibroblast growth factor 2 [131] -5.44[132] -5.17[133] -1.20[134] 2.16[135] 3.74[136] -0.35[137]
21 MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1 [138] 1.61[139] 1.25[140] 1.59[141] 1.57[142] 1.17[143] 2.01[144]
22 SRC Proto-oncogene tyrosine-protein kinase Src [145] 4.27[146] 4.27[147] 3.09[148] 3.62[149] 2.80[150] 0.46[151]
23 PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 4.73[152] 4.37[153] 3.52[154] 4.05[155] 3.54[156] 1.65[157]
24 SPRY2 Protein sprouty homolog 2 [158] 0.65[159] 0.81[160] 3.06[161] -1.05[162] 0.98[163] 1.48[164]
25 SPRED2 Sprouty-related, EVH1 domain-containing protein 2 [165] 3.33[166] 3.59[167] 3.18[168] 2.37[169] 2.77[170] 2.23[171]
26 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 0.86[172] 2.52[173] 2.53[174] 2.35[175] 2.55[176] 3.22[177]
27 FRS2 Fibroblast growth factor receptor substrate 2 [178] 2.53[179] 3.64[180] 3.96[181] 4.13[182] 3.75[183] 4.65[184]
28 BRAF Serine/threonine-protein kinase B-raf [185] 1.49[186] 1.23[187] 3.09[188] 1.97[189] 1.66[190] 3.16[191]
29 FRS3 Fibroblast growth factor receptor substrate 3 [192] 1.87[193] 1.71[194] 0.52[195] 1.52[196] 1.17[197] 0.40[198]
30 FGFR1 Fibroblast growth factor receptor 1 [199] 5.82[200] 4.15[201] 5.62[202] 6.28[203] 5.55[204] 2.97[205]
31 GAB1 GRB2-associated-binding protein 1 [206] 2.55[207] 3.65[208] 3.59[209] 3.16[210] 3.02[211] 4.18[212]
32 SPRED1 Sprouty-related, EVH1 domain-containing protein 1 [213] 3.66[214] 4.18[215] 3.92[216] 5.20[217] 5.69[218] 4.10[219]
33 CBL E3 ubiquitin-protein ligase CBL [220] 5.69[221] 4.65[222] 4.69[223] 6.36[224] 5.84[225] 5.07[226]
34 KL Klotho [227] -4.81[228] [229] [230] -0.17[231] -5.42[232] 1.56[233]
35 FGF5 Fibroblast growth factor 5 [234] 0.25[235] 1.59[236] 1.34[237] 2.71[238] 2.39[239] 4.45[240]
36 FGF1 Fibroblast growth factor 1 [241] -1.52[242] -0.72[243] -5.36[244] 1.81[245] 3.39[246] 1.35[247]
37 FLRT1 Leucine-rich repeat transmembrane protein FLRT1 [248] 3.27[249] 4.55[250] 3.41[251] 2.54[252] 3.83[253] 6.30[254]
38 FGF8 Fibroblast growth factor 8 [255] -2.08[256] -1.72[257] 2.59[258] -0.69[259] [260] 4.01[261]
39 FGF18 Fibroblast growth factor 18 [262] 3.02[263] -1.08[264] 0.91[265] 1.84[266] 2.43[267] 1.89[268]
40 FGF9 Fibroblast growth factor 9 [269] 3.50[270] -0.14[271] [272] 4.01[273] -1.11[274] 1.41[275]
41 FLRT2 Leucine-rich repeat transmembrane protein FLRT2 [276] 10.58[277] [278] 10.01[279] 11.16[280] 13.46[281] 10.01[282]
42 FGF6 Fibroblast growth factor 6 [283] [284] [285] [286] [287] [288] [289]
43 FGF23 Fibroblast growth factor 23 [290] [291] [292] [293] [294] [295] [296]
44 FGF22 Fibroblast growth factor 22 [297] [298] [299] [300] [301] [302] [303]
45 FGF10 Fibroblast growth factor 10 [304] [305] [306] [307] [308] [309] [310]
46 FGF17 Fibroblast growth factor 17 [311] [312] [313] [314] [315] [316] [317]
47 ANOS1 Anosmin-1 [318] [319] [320] [321] [322] [323] [324]
48 FGF3 Fibroblast growth factor 3 [325] [326] [327] [328] [329] [330] [331]
49 FGF20 Fibroblast growth factor 20 [332] [333] [334] [335] [336] [337] [338]
50 FGF4 Fibroblast growth factor 4 [339] [340] [341] [342] [343] [344] [345]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[23]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[24]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[25]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[26]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[27]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[28]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[29]
ref_hepatocyte PPP2R1A
Mean 27.9
Standard deviation 5.4
Values 23 30 23 36 28
[30]
HepG2 PPP2R1A
Mean 107
Standard deviation 6.5
Values 1.1e+02 1e+02
[31]
HepG2.C3A PPP2R1A
Mean 84.7
Standard deviation 12
Values 93 76
[32]
HuH.7 PPP2R1A
Mean 77.2
Standard deviation 6.8
Values 84 70 78
[33]
SNU475 PPP2R1A
Mean 118
Standard deviation 14
Values 1.3e+02 1.1e+02
[34]
THLE PPP2R1A
Mean 83.3
Standard deviation 16
Values 72 94
[35]
liver PPP2R1A
Mean 43.9
Standard deviation 17
Values 51 30 65 30
[36]
ref_hepatocyte PPP2CA
Mean 27.3
Standard deviation 6.4
Values 27 38 22 24 25
[37]
HepG2 PPP2CA
Mean 72.8
Standard deviation 15
Values 62 83
[38]
HepG2.C3A PPP2CA
Mean 69.2
Standard deviation 19
Values 55 83
[39]
HuH.7 PPP2CA
Mean 42.8
Standard deviation 4.9
Values 43 38 48
[40]
SNU475 PPP2CA
Mean 83.9
Standard deviation 4.1
Values 81 87
[41]
THLE PPP2CA
Mean 102
Standard deviation 13
Values 92 1.1e+02
[42]
liver PPP2CA
Mean 36.1
Standard deviation 13
Values 49 27 46 23
[43]
ref_hepatocyte PPP2CB
Mean 25.5
Standard deviation 11
Values 15 43 27 17 26
[44]
HepG2 PPP2CB
Mean 43
Standard deviation 1.5
Values 44 42
[45]
HepG2.C3A PPP2CB
Mean 30.2
Standard deviation 0.78
Values 31 30
[46]
HuH.7 PPP2CB
Mean 30.6
Standard deviation 2.8
Values 28 34 30
[47]
SNU475 PPP2CB
Mean 34.2
Standard deviation 0.1
Values 34 34
[48]
THLE PPP2CB
Mean 35.7
Standard deviation 2.6
Values 37 34
[49]
liver PPP2CB
Mean 18.3
Standard deviation 7.2
Values 28 14 19 12
[50]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 33 53 10 7.5 7.4
[51]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 58 76
[52]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 68 92
[53]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 86 77 61
[54]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 75 76
[55]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[56]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 60 99 62 80
[57]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[58]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[59]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[60]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[61]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[62]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[63]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[64]
ref_hepatocyte SHC1
Mean 16.6
Standard deviation 7.2
Values 5.8 17 19 26 16
[65]
HepG2 SHC1
Mean 82
Standard deviation 0.099
Values 82 82
[66]
HepG2.C3A SHC1
Mean 84.9
Standard deviation 11
Values 77 93
[67]
HuH.7 SHC1
Mean 85.9
Standard deviation 2.4
Values 89 84 85
[68]
SNU475 SHC1
Mean 191
Standard deviation 36
Values 2.2e+02 1.7e+02
[69]
THLE SHC1
Mean 150
Standard deviation 11
Values 1.4e+02 1.6e+02
[70]
liver SHC1
Mean 40.4
Standard deviation 11
Values 37 32 56 37
[71]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[72]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[73]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[74]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[75]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[76]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[77]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[78]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[79]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[80]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[81]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[82]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[83]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[84]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[85]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 14 13 13 6.1 7.4
[86]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 62 93
[87]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 71 81
[88]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 73 60 61
[89]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 77 65
[90]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[91]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 39 68 41 61
[92]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[93]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[94]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[95]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[96]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[97]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[98]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[99]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.1 7.4 4.2 8.1 14
[100]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 9.8 14
[101]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 9.6 13
[102]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 23 32 15
[103]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 80 35
[104]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[105]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 64 1e+02 32 1.4e+02
[106]
ref_hepatocyte FGFRL1
Mean 7.35
Standard deviation 3.5
Values 2.7 5 7.9 10 11
[107]
HepG2 FGFRL1
Mean 36.7
Standard deviation 9.3
Values 43 30
[108]
HepG2.C3A FGFRL1
Mean 36.4
Standard deviation 6.8
Values 41 32
[109]
HuH.7 FGFRL1
Mean 23.7
Standard deviation 7.8
Values 31 16 24
[110]
SNU475 FGFRL1
Mean 15.8
Standard deviation 2.1
Values 17 14
[111]
THLE FGFRL1
Mean 21.2
Standard deviation 6.7
Values 16 26
[112]
liver FGFRL1
Mean 18.5
Standard deviation 2
Values 20 19 16 19
[113]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 27 1.9 2.2 1.3 1.5
[114]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 9.4 19
[115]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 39 33
[116]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 22 37 15
[117]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 25 20
[118]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[119]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 13 18 9.3 16
[120]
ref_hepatocyte FLRT3
Mean 4.25
Standard deviation 6.1
Values 0.31 15 0.94 3.5 1.5
[121]
HepG2 FLRT3
Mean 3.04
Standard deviation 0.62
Values 2.6 3.5
[122]
HepG2.C3A FLRT3
Mean 0.0452
Standard deviation 0.018
Values 0.058 0.032
[123]
HuH.7 FLRT3
Mean 37.6
Standard deviation 11
Values 33 50 30
[124]
SNU475 FLRT3
Mean 9.11
Standard deviation 5.2
Values 13 5.4
[125]
THLE FLRT3
Mean 2.32
Standard deviation 0.25
Values 2.5 2.1
[126]
liver FLRT3
Mean 6.77
Standard deviation 0.91
Values 7 6.1 6.1 8
[127]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 5.1 2.8 3.6 6 3.3
[128]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 37 29
[129]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 39 22
[130]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 34 25 32
[131]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 12 8.5
[132]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[133]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 5 0.81 4.8 0.82
[134]
ref_hepatocyte FGF2
Mean 4.04
Standard deviation 6.5
Values 0.052 15 3.7 0.37 0.73
[135]
HepG2 FGF2
Mean 0.0866
Standard deviation 0.08
Values 0.14 0.03
[136]
HepG2.C3A FGF2
Mean 0.092
Standard deviation 0.0064
Values 0.087 0.097
[137]
HuH.7 FGF2
Mean 1.57
Standard deviation 0.89
Values 0.98 2.6 1.1
[138]
SNU475 FGF2
Mean 14.2
Standard deviation 1.3
Values 13 15
[139]
THLE FGF2
Mean 47.5
Standard deviation 0.66
Values 48 47
[140]
liver FGF2
Mean 1.81
Standard deviation 0.66
Values 1.9 2.5 0.9 2
[141]
ref_hepatocyte MKNK1
Mean 3.72
Standard deviation 0.64
Values 3 4.7 3.9 3.7 3.4
[142]
HepG2 MKNK1
Mean 10.6
Standard deviation 2.1
Values 9.1 12
[143]
HepG2.C3A MKNK1
Mean 7.29
Standard deviation 0.2
Values 7.4 7.2
[144]
HuH.7 MKNK1
Mean 10
Standard deviation 0.97
Values 10 8.9 11
[145]
SNU475 MKNK1
Mean 8.68
Standard deviation 2.1
Values 10 7.2
[146]
THLE MKNK1
Mean 7.38
Standard deviation 0.36
Values 7.6 7.1
[147]
liver MKNK1
Mean 8.59
Standard deviation 2.1
Values 11 6.3 10 7.3
[148]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[149]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[150]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[151]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[152]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[153]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[154]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[155]
ref_hepatocyte PLCG1
Mean 3.54
Standard deviation 4.5
Values 11 2.4 1.7 0.91 1.2
[156]
HepG2 PLCG1
Mean 87.8
Standard deviation 4.3
Values 91 85
[157]
HepG2.C3A PLCG1
Mean 60.1
Standard deviation 10
Values 67 53
[158]
HuH.7 PLCG1
Mean 36.2
Standard deviation 5.9
Values 40 30 39
[159]
SNU475 PLCG1
Mean 45.9
Standard deviation 1.9
Values 47 45
[160]
THLE PLCG1
Mean 36.2
Standard deviation 0.92
Values 36 37
[161]
liver PLCG1
Mean 6.36
Standard deviation 4.9
Values 2.3 8.9 2.2 12
[162]
ref_hepatocyte SPRY2
Mean 3.21
Standard deviation 2
Values 0.39 2.4 4.2 5.7 3.3
[163]
HepG2 SPRY2
Mean 4.68
Standard deviation 0.29
Values 4.9 4.5
[164]
HepG2.C3A SPRY2
Mean 4.63
Standard deviation 0.85
Values 5.2 4
[165]
HuH.7 SPRY2
Mean 23.8
Standard deviation 10
Values 27 12 32
[166]
SNU475 SPRY2
Mean 1.22
Standard deviation 0.58
Values 0.81 1.6
[167]
THLE SPRY2
Mean 5.56
Standard deviation 0.25
Values 5.4 5.7
[168]
liver SPRY2
Mean 5.14
Standard deviation 2.3
Values 4.7 5.4 2.4 8
[169]
ref_hepatocyte SPRED2
Mean 2.72
Standard deviation 1.4
Values 1.2 2.1 4.9 3.2 2.3
[170]
HepG2 SPRED2
Mean 25.5
Standard deviation 1.3
Values 25 26
[171]
HepG2.C3A SPRED2
Mean 27
Standard deviation 5
Values 31 23
[172]
HuH.7 SPRED2
Mean 22
Standard deviation 5.4
Values 28 17 21
[173]
SNU475 SPRED2
Mean 11.1
Standard deviation 5.1
Values 7.4 15
[174]
THLE SPRED2
Mean 16.4
Standard deviation 2.1
Values 15 18
[175]
liver SPRED2
Mean 7.3
Standard deviation 3.7
Values 13 4.5 6.7 5.3
[176]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 2.6 2.3 1.2 0.94
[177]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 2.1 4.3
[178]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 8 9.6
[179]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 10 12 7
[180]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 8.1 6.8
[181]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[182]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 6.1 15 6 13
[183]
ref_hepatocyte FRS2
Mean 1.15
Standard deviation 0.48
Values 1.3 1.9 0.69 0.74 1.2
[184]
HepG2 FRS2
Mean 6.18
Standard deviation 3
Values 4 8.3
[185]
HepG2.C3A FRS2
Mean 11.7
Standard deviation 4
Values 8.9 15
[186]
HuH.7 FRS2
Mean 15.9
Standard deviation 4.9
Values 16 21 11
[187]
SNU475 FRS2
Mean 15.7
Standard deviation 0.35
Values 16 15
[188]
THLE FRS2
Mean 13.6
Standard deviation 0.96
Values 14 13
[189]
liver FRS2
Mean 16.5
Standard deviation 3.3
Values 18 20 13 15
[190]
ref_hepatocyte BRAF
Mean 1.07
Standard deviation 0.72
Values 0.56 1.2 2.3 0.67 0.67
[191]
HepG2 BRAF
Mean 2.8
Standard deviation 0.62
Values 2.4 3.2
[192]
HepG2.C3A BRAF
Mean 2.07
Standard deviation 0.66
Values 1.6 2.5
[193]
HuH.7 BRAF
Mean 8.12
Standard deviation 5.8
Values 6.4 15 3.4
[194]
SNU475 BRAF
Mean 3.28
Standard deviation 0.16
Values 3.2 3.4
[195]
THLE BRAF
Mean 2.97
Standard deviation 0.38
Values 2.7 3.2
[196]
liver BRAF
Mean 5.48
Standard deviation 2.9
Values 3.1 8 2.9 7.9
[197]
ref_hepatocyte FRS3
Mean 0.88
Standard deviation 0.75
Values 2 0.11 0.65 0.39 1.3
[198]
HepG2 FRS3
Mean 3
Standard deviation 0.84
Values 3.6 2.4
[199]
HepG2.C3A FRS3
Mean 2.38
Standard deviation 0.57
Values 2.8 2
[200]
HuH.7 FRS3
Mean 1.13
Standard deviation 0.22
Values 1.1 0.94 1.4
[201]
SNU475 FRS3
Mean 1.98
Standard deviation 0.18
Values 2.1 1.9
[202]
THLE FRS3
Mean 1.75
Standard deviation 0.21
Values 1.9 1.6
[203]
liver FRS3
Mean 0.666
Standard deviation 0.45
Values 1.1 0.26 0.98 0.3
[204]
ref_hepatocyte FGFR1
Mean 0.81
Standard deviation 0.63
Values 1.2 0.49 1.6 0.06 0.62
[205]
HepG2 FGFR1
Mean 42.7
Standard deviation 4
Values 40 46
[206]
HepG2.C3A FGFR1
Mean 11.8
Standard deviation 3.5
Values 9.3 14
[207]
HuH.7 FGFR1
Mean 35.6
Standard deviation 13
Values 43 20 43
[208]
SNU475 FGFR1
Mean 49.5
Standard deviation 1.4
Values 50 49
[209]
THLE FGFR1
Mean 33.4
Standard deviation 3.3
Values 36 31
[210]
liver FGFR1
Mean 3.64
Standard deviation 0.67
Values 3 4.2 3.2 4.3
[211]
ref_hepatocyte GAB1
Mean 0.787
Standard deviation 0.67
Values 2 0.61 0.33 0.38 0.66
[212]
HepG2 GAB1
Mean 4.28
Standard deviation 2.2
Values 2.8 5.8
[213]
HepG2.C3A GAB1
Mean 8.12
Standard deviation 2.3
Values 6.5 9.8
[214]
HuH.7 GAB1
Mean 8.48
Standard deviation 1.4
Values 10 8.1 7.3
[215]
SNU475 GAB1
Mean 5.52
Standard deviation 1.6
Values 6.6 4.4
[216]
THLE GAB1
Mean 5.62
Standard deviation 0.39
Values 5.9 5.3
[217]
liver GAB1
Mean 8.2
Standard deviation 2.5
Values 7.1 10 5.3 10
[218]
ref_hepatocyte SPRED1
Mean 0.719
Standard deviation 0.37
Values 1.1 1.1 0.36 0.37 0.67
[219]
HepG2 SPRED1
Mean 8.47
Standard deviation 0.51
Values 8.1 8.8
[220]
HepG2.C3A SPRED1
Mean 10.7
Standard deviation 0.75
Values 11 10
[221]
HuH.7 SPRED1
Mean 9.7
Standard deviation 2.9
Values 13 6.9 9.5
[222]
SNU475 SPRED1
Mean 20.8
Standard deviation 6.4
Values 16 25
[223]
THLE SPRED1
Mean 32.6
Standard deviation 0.87
Values 32 33
[224]
liver SPRED1
Mean 7.06
Standard deviation 3.6
Values 3.9 11 4.3 8.8
[225]
ref_hepatocyte CBL
Mean 0.522
Standard deviation 0.26
Values 0.83 0.62 0.65 0.18 0.33
[226]
HepG2 CBL
Mean 25.2
Standard deviation 0.64
Values 26 25
[227]
HepG2.C3A CBL
Mean 10.8
Standard deviation 0.61
Values 11 10
[228]
HuH.7 CBL
Mean 12.1
Standard deviation 3
Values 15 11 9.5
[229]
SNU475 CBL
Mean 33.7
Standard deviation 5.1
Values 30 37
[230]
THLE CBL
Mean 26.4
Standard deviation 3.4
Values 24 29
[231]
liver CBL
Mean 10
Standard deviation 4.2
Values 5.8 14 7.1 14
[232]
ref_hepatocyte KL
Mean 0.258
Standard deviation 0.29
Values 0 0 0.4 0.2 0.69
[233]
HepG2 KL
Mean 0.00858
Standard deviation 0.012
Values 0 0.017
[234]
HepG2.C3A KL
Mean 0
Standard deviation 0
Values 0 0
[235]
HuH.7 KL
Mean 0
Standard deviation 0
Values 0 0 0
[236]
SNU475 KL
Mean 0.181
Standard deviation 0.026
Values 0.2 0.16
[237]
THLE KL
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[238]
liver KL
Mean 0.436
Standard deviation 0.32
Values 0.38 0.31 0.15 0.9
[239]
ref_hepatocyte FGF5
Mean 0.241
Standard deviation 0.27
Values 0.042 0.036 0.09 0.64 0.4
[240]
HepG2 FGF5
Mean 0.268
Standard deviation 0.022
Values 0.25 0.28
[241]
HepG2.C3A FGF5
Mean 0.596
Standard deviation 0.024
Values 0.61 0.58
[242]
HuH.7 FGF5
Mean 0.543
Standard deviation 0.15
Values 0.62 0.65 0.37
[243]
SNU475 FGF5
Mean 1.24
Standard deviation 0.35
Values 0.99 1.5
[244]
THLE FGF5
Mean 1.11
Standard deviation 0.17
Values 0.99 1.2
[245]
liver FGF5
Mean 3.01
Standard deviation 1.5
Values 2.3 4.5 1.2 4.1
[246]
ref_hepatocyte FGF1
Mean 0.126
Standard deviation 0.27
Values 0 0.6 0 0 0.024
[247]
HepG2 FGF1
Mean 0.0408
Standard deviation 0.04
Values 0.069 0.013
[248]
HepG2.C3A FGF1
Mean 0.0628
Standard deviation 0.048
Values 0.029 0.097
[249]
HuH.7 FGF1
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[250]
SNU475 FGF1
Mean 0.346
Standard deviation 0.077
Values 0.29 0.4
[251]
THLE FGF1
Mean 1.16
Standard deviation 0.44
Values 0.85 1.5
[252]
liver FGF1
Mean 0.184
Standard deviation 0.042
Values 0.14 0.21 0.15 0.23
[253]
ref_hepatocyte FLRT1
Mean 0.0324
Standard deviation 0.036
Values 0.035 0 0 0.086 0.041
[254]
HepG2 FLRT1
Mean 0.293
Standard deviation 0.0075
Values 0.3 0.29
[255]
HepG2.C3A FLRT1
Mean 0.623
Standard deviation 0.12
Values 0.71 0.54
[256]
HuH.7 FLRT1
Mean 0.308
Standard deviation 0.11
Values 0.3 0.42 0.21
[257]
SNU475 FLRT1
Mean 0.148
Standard deviation 0.085
Values 0.088 0.21
[258]
THLE FLRT1
Mean 0.407
Standard deviation 0.086
Values 0.47 0.35
[259]
liver FLRT1
Mean 1.47
Standard deviation 0.96
Values 0.56 2.2 0.72 2.4
[260]
ref_hepatocyte FGF8
Mean 0.0195
Standard deviation 0.044
Values 0 0 0 0 0.098
[261]
HepG2 FGF8
Mean 0.00429
Standard deviation 0.0061
Values 0 0.0086
[262]
HepG2.C3A FGF8
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[263]
HuH.7 FGF8
Mean 0.105
Standard deviation 0.073
Values 0.19 0.051 0.075
[264]
SNU475 FGF8
Mean 0.00949
Standard deviation 0.0063
Values 0.014 0.0051
[265]
THLE FGF8
Mean 0
Standard deviation 0
Values 0 0
[266]
liver FGF8
Mean 0.18
Standard deviation 0.14
Values 0.047 0.34 0.077 0.25
[267]
ref_hepatocyte FGF18
Mean 0.0138
Standard deviation 0.031
Values 0 0 0 0.069 0
[268]
HepG2 FGF18
Mean 0.105
Standard deviation 0.039
Values 0.13 0.077
[269]
HepG2.C3A FGF18
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[270]
HuH.7 FGF18
Mean 0.0232
Standard deviation 0.02
Values 0 0.032 0.037
[271]
SNU475 FGF18
Mean 0.0388
Standard deviation 0.0024
Values 0.037 0.041
[272]
THLE FGF18
Mean 0.0657
Standard deviation 0.033
Values 0.089 0.043
[273]
liver FGF18
Mean 0.0294
Standard deviation 0.0072
Values 0.024 0.029 0.026 0.04
[274]
ref_hepatocyte FGF9
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[275]
HepG2 FGF9
Mean 0.0687
Standard deviation 9.1e-05
Values 0.069 0.069
[276]
HepG2.C3A FGF9
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[277]
HuH.7 FGF9
Mean 0
Standard deviation 0
Values 0 0 0
[278]
SNU475 FGF9
Mean 0.0822
Standard deviation 0.08
Values 0.14 0.025
[279]
THLE FGF9
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[280]
liver FGF9
Mean 0.00993
Standard deviation 0.02
Values 0 0 0 0.04
[281]
ref_hepatocyte FLRT2
Mean 0.00271
Standard deviation 0.0038
Values 0 0 0.0054 0 0.0081
[282]
HepG2 FLRT2
Mean 3.88
Standard deviation 0.6
Values 3.5 4.3
[283]
HepG2.C3A FLRT2
Mean 0
Standard deviation 0
Values 0 0
[284]
HuH.7 FLRT2
Mean 2.49
Standard deviation 2
Values 1.5 4.8 1.2
[285]
SNU475 FLRT2
Mean 4.86
Standard deviation 1.8
Values 3.6 6.1
[286]
THLE FLRT2
Mean 27.1
Standard deviation 9.4
Values 20 34
[287]
liver FLRT2
Mean 1.6
Standard deviation 0.7
Values 1.7 1.9 0.62 2.3
[288]
ref_hepatocyte FGF6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[289]
HepG2 FGF6
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[290]
HepG2.C3A FGF6
Mean 0
Standard deviation 0
Values 0 0
[291]
HuH.7 FGF6
Mean 0
Standard deviation 0
Values 0 0 0
[292]
SNU475 FGF6
Mean 0
Standard deviation 0
Values 0 0
[293]
THLE FGF6
Mean 0
Standard deviation 0
Values 0 0
[294]
liver FGF6
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[295]
ref_hepatocyte FGF23
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[296]
HepG2 FGF23
Mean 0
Standard deviation 0
Values 0 0
[297]
HepG2.C3A FGF23
Mean 0
Standard deviation 0
Values 0 0
[298]
HuH.7 FGF23
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[299]
SNU475 FGF23
Mean 0
Standard deviation 0
Values 0 0
[300]
THLE FGF23
Mean 0
Standard deviation 0
Values 0 0
[301]
liver FGF23
Mean 0.68
Standard deviation 0.31
Values 0.59 0.67 1.1 0.36
[302]
ref_hepatocyte FGF22
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[303]
HepG2 FGF22
Mean 0.01
Standard deviation 0.002
Values 0.011 0.0086
[304]
HepG2.C3A FGF22
Mean 0
Standard deviation 0
Values 0 0
[305]
HuH.7 FGF22
Mean 0.00625
Standard deviation 0.011
Values 0 0 0.019
[306]
SNU475 FGF22
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[307]
THLE FGF22
Mean 0
Standard deviation 0
Values 0 0
[308]
liver FGF22
Mean 0
Standard deviation 0
Values 0 0 0 0
[309]
ref_hepatocyte FGF10
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[310]
HepG2 FGF10
Mean 0
Standard deviation 0
Values 0 0
[311]
HepG2.C3A FGF10
Mean 0
Standard deviation 0
Values 0 0
[312]
HuH.7 FGF10
Mean 0
Standard deviation 0
Values 0 0 0
[313]
SNU475 FGF10
Mean 0
Standard deviation 0
Values 0 0
[314]
THLE FGF10
Mean 0
Standard deviation 0
Values 0 0
[315]
liver FGF10
Mean 0.0234
Standard deviation 0.038
Values 0 0.014 0 0.079
[316]
ref_hepatocyte FGF17
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[317]
HepG2 FGF17
Mean 0.398
Standard deviation 0.15
Values 0.5 0.29
[318]
HepG2.C3A FGF17
Mean 1.23
Standard deviation 1.1
Values 2 0.46
[319]
HuH.7 FGF17
Mean 0.183
Standard deviation 0.2
Values 0.074 0.41 0.066
[320]
SNU475 FGF17
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[321]
THLE FGF17
Mean 0.0228
Standard deviation 0.0096
Values 0.03 0.016
[322]
liver FGF17
Mean 0.00588
Standard deviation 0.012
Values 0.024 0 0 0
[323]
ref_hepatocyte ANOS1
Missing
[324]
HepG2 ANOS1
Missing
[325]
HepG2.C3A ANOS1
Missing
[326]
HuH.7 ANOS1
Missing
[327]
SNU475 ANOS1
Missing
[328]
THLE ANOS1
Missing
[329]
liver ANOS1
Missing
[330]
ref_hepatocyte FGF3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[331]
HepG2 FGF3
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[332]
HepG2.C3A FGF3
Mean 0
Standard deviation 0
Values 0 0
[333]
HuH.7 FGF3
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[334]
SNU475 FGF3
Mean 0.00717
Standard deviation 0.003
Values 0.0093 0.0051
[335]
THLE FGF3
Mean 0
Standard deviation 0
Values 0 0
[336]
liver FGF3
Mean 0
Standard deviation 0
Values 0 0 0 0
[337]
ref_hepatocyte FGF20
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[338]
HepG2 FGF20
Mean 0.0115
Standard deviation 0.016
Values 0.023 0
[339]
HepG2.C3A FGF20
Mean 0
Standard deviation 0
Values 0 0
[340]
HuH.7 FGF20
Mean 0
Standard deviation 0
Values 0 0 0
[341]
SNU475 FGF20
Mean 0.00485
Standard deviation 0.0003
Values 0.0046 0.0051
[342]
THLE FGF20
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[343]
liver FGF20
Mean 0.0118
Standard deviation 0.024
Values 0.047 0 0 0
[344]
ref_hepatocyte FGF4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[345]
HepG2 FGF4
Mean 0
Standard deviation 0
Values 0 0
[346]
HepG2.C3A FGF4
Mean 0
Standard deviation 0
Values 0 0
[347]
HuH.7 FGF4
Mean 0
Standard deviation 0
Values 0 0 0
[348]
SNU475 FGF4
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[349]
THLE FGF4
Mean 0
Standard deviation 0
Values 0 0
[350]
liver FGF4
Mean 0
Standard deviation 0
Values 0 0 0 0