REACTOME_AURKA_ACTIVATION_BY_TPX2 | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | HSP90AA1 | Heat shock protein HSP 90-alpha | [1] | -0.90[2] | -0.01[3] | -0.74[4] | -0.34[5] | -0.45[6] | -0.60[7] |
2 | YWHAE | 14-3-3 protein epsilon | [8] | -1.49[9] | -1.46[10] | -1.08[11] | -1.29[12] | -1.05[13] | -0.90[14] |
3 | TUBB4B | Tubulin beta-4B chain | [15] | -1.04[16] | -1.22[17] | -1.21[18] | -2.07[19] | -0.97[20] | -0.80[21] |
4 | TUBB | Tubulin beta chain | [22] | 1.53[23] | 0.72[24] | 1.15[25] | 1.14[26] | 0.66[27] | -0.11[28] |
5 | DYNLL1 | Dynein light chain 1, cytoplasmic | [29] | -1.64[30] | -1.68[31] | -1.86[32] | -2.05[33] | -2.12[34] | -1.45[35] |
6 | TUBA4A | Tubulin alpha-4A chain | [36] | -4.30[37] | -4.55[38] | -5.28[39] | -2.23[40] | -2.19[41] | -1.96[42] |
7 | CETN2 | Centrin-2 | [43] | -2.87[44] | -2.56[45] | -3.69[46] | -3.09[47] | -3.31[48] | -2.83[49] |
8 | YWHAG | 14-3-3 protein gamma | [50] | -0.05[51] | -0.67[52] | -0.57[53] | 0.29[54] | -0.20[55] | -0.69[56] |
9 | DCTN2 | Dynactin subunit 2 | [57] | -0.64[58] | -0.26[59] | -0.44[60] | -0.58[61] | -0.55[62] | -0.79[63] |
10 | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isofor | 0.54[64] | 0.29[65] | 0.25[66] | 0.78[67] | 0.31[68] | 0.80[69] | |
11 | SSNA1 | Sjoegren syndrome nuclear autoantigen 1 | [70] | -1.70[71] | -1.84[72] | -1.79[73] | -2.08[74] | -1.95[75] | -1.27[76] |
12 | MAPRE1 | Microtubule-associated protein RP/EB family member 1 | [77] | 1.42[78] | 0.93[79] | 0.31[80] | 1.27[81] | 0.69[82] | -0.89[83] |
13 | HAUS4 | HAUS augmin-like complex subunit 4 | [84] | -0.51[85] | -1.83[86] | 0.39[87] | -2.38[88] | -1.77[89] | -2.75[90] |
14 | DCTN3 | Dynactin subunit 3 | [91] | -2.21[92] | -2.09[93] | -1.90[94] | -2.48[95] | -1.19[96] | -0.90[97] |
15 | CSNK1D | Casein kinase I isoform delta | [98] | 0.92[99] | 0.60[100] | 0.55[101] | 0.60[102] | 0.34[103] | 0.06[104] |
16 | TUBG1 | Tubulin gamma-1 chain | [105] | -0.01[106] | 0.79[107] | -0.20[108] | -0.91[109] | -0.67[110] | -0.80[111] |
17 | DYNC1I2 | Cytoplasmic dynein 1 intermediate chain 2 | [112] | 0.17[113] | 0.55[114] | 0.38[115] | 0.37[116] | 0.23[117] | 0.08[118] |
18 | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha | [119] | -0.42[120] | -0.67[121] | -0.64[122] | -0.90[123] | -0.11[124] | -0.12[125] |
19 | ACTR1A | Alpha-centractin | [126] | 0.71[127] | 0.80[128] | 0.97[129] | 0.07[130] | 1.07[131] | 1.03[132] |
20 | DCTN1 | Dynactin subunit 1 | [133] | 1.61[134] | 0.68[135] | 0.07[136] | 1.00[137] | 1.21[138] | 1.21[139] |
21 | PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha | [140] | 0.53[141] | 0.57[142] | 0.55[143] | 1.71[144] | 1.78[145] | 1.50[146] |
22 | DYNC1H1 | Cytoplasmic dynein 1 heavy chain 1 | [147] | 3.31[148] | 1.83[149] | 2.67[150] | 3.23[151] | 3.44[152] | 3.85[153] |
23 | AURKA | Aurora kinase A | [154] | 1.45[155] | 1.63[156] | 1.17[157] | 1.19[158] | 1.30[159] | -2.15[160] |
24 | CEP57 | Centrosomal protein of 57 kDa | [161] | -0.40[162] | 1.17[163] | 1.57[164] | 0.13[165] | 0.03[166] | 1.66[167] |
25 | CSNK1E | Casein kinase I isoform epsilon | [168] | 1.11[169] | 0.66[170] | 1.36[171] | 0.04[172] | 1.31[173] | -0.17[174] |
26 | HAUS1 | HAUS augmin-like complex subunit 1 | [175] | -0.76[176] | 0.26[177] | -0.22[178] | -0.52[179] | 0.06[180] | -1.23[181] |
27 | CDK5RAP2 | CDK5 regulatory subunit-associated protein 2 | [182] | 1.12[183] | 1.29[184] | 1.31[185] | 1.47[186] | 1.23[187] | 1.59[188] |
28 | CDK1 | Cyclin-dependent kinase 1 | [189] | 1.00[190] | 2.98[191] | 1.75[192] | 1.84[193] | 2.86[194] | -1.81[195] |
29 | CEP63 | Centrosomal protein of 63 kDa | [196] | -2.03[197] | -0.58[198] | -0.61[199] | -1.71[200] | -1.15[201] | 0.21[202] |
30 | CKAP5 | Cytoskeleton-associated protein 5 | [203] | 2.21[204] | 2.29[205] | 3.03[206] | 2.06[207] | 2.58[208] | 2.15[209] |
31 | ODF2 | Outer dense fiber protein 2 | [210] | 0.44[211] | 0.75[212] | 1.28[213] | 0.41[214] | 0.92[215] | 1.07[216] |
32 | PCM1 | Pericentriolar material 1 protein | [217] | 0.62[218] | 2.47[219] | 2.53[220] | 1.01[221] | 1.30[222] | 3.82[223] |
33 | PLK1 | Serine/threonine-protein kinase PLK1 | [224] | 2.24[225] | 1.90[226] | 1.79[227] | 0.82[228] | 2.06[229] | -1.97[230] |
34 | CEP70 | Centrosomal protein of 70 kDa | [231] | -2.16[232] | -0.33[233] | 0.23[234] | -0.94[235] | -0.58[236] | 1.19[237] |
35 | TPX2 | Targeting protein for Xklp2 | [238] | 3.01[239] | 2.85[240] | 3.88[241] | 2.97[242] | 3.25[243] | -0.58[244] |
36 | TUBA1A | Tubulin alpha-1A chain | [245] | 1.91[246] | -1.54[247] | -4.70[248] | 3.66[249] | 1.38[250] | 0.66[251] |
37 | HAUS2 | HAUS augmin-like complex subunit 2 | [252] | 0.78[253] | 0.79[254] | 0.77[255] | 1.38[256] | 1.51[257] | 0.28[258] |
38 | HMMR | Hyaluronan mediated motility receptor | [259] | -0.56[260] | 2.43[261] | 1.93[262] | 1.01[263] | 2.08[264] | -1.00[265] |
39 | NINL | Ninein-like protein | [266] | 1.80[267] | 2.17[268] | 1.71[269] | 0.55[270] | -0.62[271] | 0.61[272] |
40 | HAUS8 | HAUS augmin-like complex subunit 8 | [273] | -0.38[274] | -0.20[275] | 0.80[276] | -0.52[277] | 0.18[278] | -0.60[279] |
41 | HAUS7 | HAUS augmin-like complex subunit 7 | [280] | 0.13[281] | -0.05[282] | -0.06[283] | -0.65[284] | -0.28[285] | 0.59[286] |
42 | CLASP1 | CLIP-associating protein 1 | [287] | 2.28[288] | 2.19[289] | 1.92[290] | 2.09[291] | 2.35[292] | 3.57[293] |
43 | HAUS6 | HAUS augmin-like complex subunit 6 | [294] | 1.06[295] | 2.25[296] | 2.05[297] | 1.38[298] | 2.30[299] | 1.70[300] |
44 | SDCCAG8 | Serologically defined colon cancer antigen 8 | [301] | -0.99[302] | -0.23[303] | -0.05[304] | 0.00[305] | -0.62[306] | 1.75[307] |
45 | OFD1 | Oral-facial-digital syndrome 1 protein | [308] | -0.73[309] | 0.94[310] | 0.91[311] | 0.37[312] | 0.29[313] | 1.96[314] |
46 | NEDD1 | Protein NEDD1 | [315] | 0.16[316] | 1.41[317] | 0.97[318] | 1.84[319] | 2.08[320] | 1.27[321] |
47 | AKAP9 | A-kinase anchor protein 9 | [322] | -0.23[323] | 2.40[324] | 2.62[325] | 1.37[326] | 1.69[327] | 5.73[328] |
48 | NEK2 | Serine/threonine-protein kinase Nek2 | [329] | 0.77[330] | 1.75[331] | 2.40[332] | 1.71[333] | 2.37[334] | -1.62[335] |
49 | CEP250 | Centrosome-associated protein CEP250 | [336] | 3.23[337] | 2.79[338] | 2.81[339] | 2.88[340] | 2.41[341] | 2.01[342] |
50 | NDE1 | Nuclear distribution protein nudE homolog 1 | [343] | 2.41[344] | 1.60[345] | 0.64[346] | 0.33[347] | 1.50[348] | 0.60[349] |
51 | CEP164 | Centrosomal protein of 164 kDa | [350] | 1.87[351] | 1.84[352] | 1.64[353] | 2.01[354] | 1.89[355] | 2.01[356] |
52 | CCP110 | Centriolar coiled-coil protein of 110 kDa | [357] | 0.70[358] | 1.47[359] | 0.33[360] | 0.52[361] | 1.74[362] | 2.00[363] |
53 | CEP78 | Centrosomal protein of 78 kDa | [364] | 0.38[365] | 1.19[366] | 1.85[367] | 0.95[368] | 2.00[369] | 1.53[370] |
54 | HAUS3 | HAUS augmin-like complex subunit 3 | [371] | 0.16[372] | 1.25[373] | 1.71[374] | 1.71[375] | 1.78[376] | 1.98[377] |
55 | HAUS5 | HAUS augmin-like complex subunit 5 | [378] | 1.24[379] | 1.84[380] | 3.18[381] | 1.22[382] | 1.92[383] | 1.26[384] |
56 | CEP76 | Centrosomal protein of 76 kDa | [385] | 0.90[386] | 1.83[387] | 2.44[388] | 1.22[389] | 1.22[390] | 1.38[391] |
57 | SFI1 | Protein SFI1 homolog | [392] | 1.51[393] | 3.31[394] | 2.17[395] | 0.77[396] | 1.12[397] | 1.83[398] |
58 | PCNT | Pericentrin | [399] | 2.42[400] | 2.79[401] | 2.26[402] | 3.03[403] | 3.05[404] | 4.50[405] |
59 | CEP290 | Centrosomal protein of 290 kDa | [406] | 0.01[407] | 3.00[408] | 1.95[409] | 1.72[410] | 1.87[411] | 2.51[412] |
60 | CENPJ | Centromere protein J | [413] | 0.22[414] | 1.91[415] | 2.11[416] | 2.39[417] | 1.93[418] | 1.46[419] |
61 | CEP192 | Centrosomal protein of 192 kDa | [420] | 1.97[421] | 3.35[422] | 4.49[423] | 3.33[424] | 3.34[425] | 4.37[426] |
62 | PLK4 | Serine/threonine-protein kinase PLK4 | [427] | 1.57[428] | 3.13[429] | 2.24[430] | 2.15[431] | 3.22[432] | -0.48[433] |
63 | CNTRL | Centriolin | [434] | 0.75[435] | 2.91[436] | 3.79[437] | 2.33[438] | 2.23[439] | 3.23[440] |
64 | CEP72 | Centrosomal protein of 72 kDa | [441] | 0.93[442] | 0.83[443] | 1.90[444] | 0.44[445] | 1.12[446] | 1.75[447] |
65 | CEP135 | Centrosomal protein of 135 kDa | [448] | 0.20[449] | 1.42[450] | 1.10[451] | 1.66[452] | 1.82[453] | 2.00[454] |
66 | CEP41 | Centrosomal protein of 41 kDa | [455] | 1.86[456] | 1.63[457] | 2.47[458] | 2.81[459] | 2.80[460] | 2.41[461] |
67 | ALMS1 | Alstrom syndrome protein 1 | [462] | 2.39[463] | 3.89[464] | 3.77[465] | 3.56[466] | 3.60[467] | 5.29[468] |
68 | CEP152 | Centrosomal protein of 152 kDa | [469] | 1.38[470] | 3.29[471] | 3.51[472] | 3.42[473] | 3.68[474] | 3.57[475] |
69 | PRKAR2B | cAMP-dependent protein kinase type II-beta regulatory subunit | [476] | -2.60[477] | -0.85[478] | 3.47[479] | 4.66[480] | 3.37[481] | 3.97[482] |
70 | TUBB4A | Tubulin beta-4A chain | [483] | 1.57[484] | -2.63[485] | 3.94[486] | 3.21[487] | 1.97[488] | 2.50[489] |
71 | CEP43 | [490] | [491] | [492] | [493] | [494] | [495] | [496] | |
72 | CEP131 | Centrosomal protein of 131 kDa | [497] | [498] | [499] | [500] | [501] | [502] | [503] |