REACTOME_SIGNALING_BY_EGFR Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -1.03[2] -1.35[3] -1.24[4] -1.64[5] -1.15[6] -0.69[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] -0.59[16] -0.60[17] -0.87[18] -0.79[19] -0.77[20] -0.24[21]
4 CDC42 Cell division control protein 42 homolog [22] 0.34[23] 0.94[24] -0.10[25] 0.61[26] -0.08[27] -0.90[28]
5 UBA52 Ubiquitin-60S ribosomal protein L40 [29] 1.85[30] 1.63[31] 2.64[32] 0.61[33] 1.46[34] 0.53[35]
6 AAMP Angio-associated migratory cell protein [36] 1.25[37] 1.25[38] 1.21[39] 0.23[40] 0.23[41] 0.81[42]
7 EPN1 Epsin-1 [43] 1.18[44] 0.70[45] 0.77[46] 0.57[47] 1.02[48] 0.43[49]
8 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [50] 1.61[51] 1.92[52] 1.84[53] 2.03[54] 2.69[55] 2.45[56]
9 GRB2 Growth factor receptor-bound protein 2 [57] 2.36[58] 2.08[59] 2.16[60] 1.69[61] 1.64[62] 1.49[63]
10 HGS Hepatocyte growth factor-regulated tyrosine kinase substrate [64] 2.06[65] 1.45[66] 0.89[67] 1.64[68] 1.59[69] 0.41[70]
11 SHC1 SHC-transforming protein 1 [71] 2.33[72] 2.43[73] 2.47[74] 3.79[75] 3.31[76] 1.97[77]
12 NRAS GTPase NRas [78] 1.79[79] 2.11[80] 2.48[81] 2.14[82] 1.74[83] 0.94[84]
13 SH3GL1 Endophilin-A2 [85] 2.24[86] 2.51[87] 1.63[88] 1.68[89] 2.05[90] 0.75[91]
14 HRAS GTPase HRas [92] 0.16[93] -0.67[94] -1.50[95] 0.19[96] 0.01[97] -1.47[98]
15 CSK Tyrosine-protein kinase CSK [99] 1.54[100] 0.92[101] 1.26[102] 1.13[103] 0.76[104] 0.32[105]
16 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 [106] 1.95[107] 2.21[108] 1.14[109] 2.90[110] 2.01[111] 0.74[112]
17 PXN Paxillin [113] 2.17[114] 1.77[115] 1.77[116] 3.26[117] 3.25[118] 0.84[119]
18 KRAS GTPase KRas [120] 0.65[121] 0.51[122] 2.07[123] 1.94[124] 1.63[125] 1.86[126]
19 ADAM10 Disintegrin and metalloproteinase domain-containing protein 10 [127] 2.15[128] 2.51[129] 2.50[130] 2.42[131] 2.86[132] 1.99[133]
20 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [134] 0.69[135] 0.69[136] 1.75[137] 3.21[138] 2.74[139] 4.19[140]
21 PTPRK Receptor-type tyrosine-protein phosphatase kappa [141] 2.35[142] 3.20[143] 2.69[144] 1.74[145] 1.49[146] 3.31[147]
22 SOS1 Son of sevenless homolog 1 [148] 1.07[149] 2.48[150] 1.95[151] 1.99[152] 1.25[153] 1.73[154]
23 PTPN3 Tyrosine-protein phosphatase non-receptor type 3 [155] 1.57[156] 1.72[157] 1.92[158] 0.85[159] 1.80[160] 3.75[161]
24 LRIG1 Leucine-rich repeats and immunoglobulin-like domains protein 1 [162] -0.06[163] 1.19[164] 1.98[165] -1.77[166] 0.16[167] 2.68[168]
25 EGFR Epidermal growth factor receptor [169] 0.47[170] -0.02[171] 2.82[172] 1.57[173] 2.22[174] 3.84[175]
26 AREG Amphiregulin [176] -1.70[177] -5.06[178] -6.85[179] -8.56[180] 1.78[181] -9.12[182]
27 ADAM17 Disintegrin and metalloproteinase domain-containing protein 17 [183] 1.84[184] 1.60[185] 1.31[186] 2.88[187] 2.05[188] 1.27[189]
28 EPS15 Epidermal growth factor receptor substrate 15 [190] 1.31[191] 2.07[192] 2.32[193] 2.73[194] 2.29[195] 3.43[196]
29 STAM Signal transducing adapter molecule 1 [197] 2.22[198] 2.54[199] 1.55[200] 2.83[201] 2.17[202] 0.94[203]
30 STAM2 Signal transducing adapter molecule 2 [204] 1.43[205] 2.09[206] 1.17[207] 2.70[208] 2.01[209] 2.39[210]
31 SH3KBP1 SH3 domain-containing kinase-binding protein 1 [211] 2.76[212] 2.51[213] 3.20[214] 2.93[215] 3.45[216] 1.67[217]
32 SRC Proto-oncogene tyrosine-protein kinase Src [218] 4.19[219] 4.05[220] 3.02[221] 3.54[222] 2.75[223] 0.34[224]
33 PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 4.66[225] 4.16[226] 3.45[227] 3.96[228] 3.49[229] 1.53[230]
34 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 [231] 2.10[232] 1.83[233] 2.58[234] 1.57[235] 2.32[236] 1.49[237]
35 SPRY2 Protein sprouty homolog 2 [238] 0.57[239] 0.60[240] 2.98[241] -1.13[242] 0.93[243] 1.36[244]
36 ARHGEF7 Rho guanine nucleotide exchange factor 7 [245] 2.78[246] 2.66[247] 2.48[248] 2.96[249] 2.74[250] 3.54[251]
37 TGFA Protransforming growth factor alpha [252] 2.96[253] 3.90[254] -7.18[255] 0.18[256] -1.01[257] 0.79[258]
38 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 0.79[259] 2.30[260] 2.46[261] 2.27[262] 2.51[263] 3.10[264]
39 HBEGF Proheparin-binding EGF-like growth factor [265] 0.18[266] -0.75[267] -1.86[268] 1.45[269] 1.16[270] -1.24[271]
40 BTC Probetacellulin [272] -6.98[273] -7.49[274] -3.30[275] -1.73[276] -1.73[277] -1.73[278]
41 SPRY1 Protein sprouty homolog 1 [279] 3.41[280] 4.15[281] 3.80[282] 1.48[283] 3.24[284] 3.25[285]
42 GAB1 GRB2-associated-binding protein 1 [286] 2.47[287] 3.44[288] 3.52[289] 3.07[290] 2.97[291] 4.06[292]
43 CBL E3 ubiquitin-protein ligase CBL [293] 5.61[294] 4.44[295] 4.62[296] 6.28[297] 5.79[298] 4.95[299]
44 PAG1 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 0.39[300] -0.57[301] 5.96[302] 4.01[303] 5.18[304] 5.96[305]
45 EREG Proepiregulin [306] 2.92[307] 2.73[308] -1.73[309] -0.42[310] 4.86[311] -0.29[312]
46 SH3GL2 Endophilin-A1 [313] -1.09[314] [315] -4.04[316] 2.16[317] 0.96[318] 1.37[319]
47 ADAM12 Disintegrin and metalloproteinase domain-containing protein 12 [320] 0.49[321] 0.88[322] -0.04[323] 11.52[324] 8.54[325] 5.37[326]
48 EGF Pro-epidermal growth factor [327] 3.13[328] 4.80[329] 8.38[330] 10.17[331] 7.62[332] 2.77[333]
49 EPGN Epigen [334] [335] [336] [337] [338] [339] [340]
50 SH3GL3 Endophilin-A3 [341] [342] [343] [344] [345] [346] [347]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte CDC42
Mean 121
Standard deviation 1e+02
Values 1.6e+02 2.8e+02 75 45 46
[23]
HepG2 CDC42
Mean 150
Standard deviation 13
Values 1.4e+02 1.6e+02
[24]
HepG2.C3A CDC42
Mean 220
Standard deviation 55
Values 1.8e+02 2.6e+02
[25]
HuH.7 CDC42
Mean 105
Standard deviation 19
Values 1.2e+02 83 1.1e+02
[26]
SNU475 CDC42
Mean 153
Standard deviation 20
Values 1.7e+02 1.4e+02
[27]
THLE CDC42
Mean 104
Standard deviation 15
Values 93 1.1e+02
[28]
liver CDC42
Mean 40.5
Standard deviation 9.1
Values 42 43 49 28
[29]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[30]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[31]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[32]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[33]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[34]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[35]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[36]
ref_hepatocyte AAMP
Mean 31.6
Standard deviation 8.5
Values 19 26 37 37 39
[37]
HepG2 AAMP
Mean 74.1
Standard deviation 12
Values 82 66
[38]
HepG2.C3A AAMP
Mean 71.9
Standard deviation 5.7
Values 76 68
[39]
HuH.7 AAMP
Mean 68.6
Standard deviation 23
Values 74 44 88
[40]
SNU475 AAMP
Mean 30.9
Standard deviation 0.7
Values 31 30
[41]
THLE AAMP
Mean 33.9
Standard deviation 6
Values 30 38
[42]
liver AAMP
Mean 34.6
Standard deviation 19
Values 50 19 51 18
[43]
ref_hepatocyte EPN1
Mean 26.6
Standard deviation 11
Values 14 16 32 39 32
[44]
HepG2 EPN1
Mean 59.5
Standard deviation 12
Values 68 51
[45]
HepG2.C3A EPN1
Mean 41.2
Standard deviation 16
Values 53 30
[46]
HuH.7 EPN1
Mean 42.4
Standard deviation 13
Values 54 28 45
[47]
SNU475 EPN1
Mean 32.8
Standard deviation 4.6
Values 36 30
[48]
THLE EPN1
Mean 49.1
Standard deviation 7.4
Values 44 54
[49]
liver EPN1
Mean 22.4
Standard deviation 10
Values 18 24 12 36
[50]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 33 53 10 7.5 7.4
[51]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 58 76
[52]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 68 92
[53]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 86 77 61
[54]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 75 76
[55]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[56]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 60 99 62 80
[57]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[58]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[59]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[60]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[61]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[62]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[63]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[64]
ref_hepatocyte HGS
Mean 16.6
Standard deviation 15
Values 6.9 15 42 11 8.1
[65]
HepG2 HGS
Mean 68.4
Standard deviation 17
Values 80 57
[66]
HepG2.C3A HGS
Mean 43.2
Standard deviation 8
Values 49 38
[67]
HuH.7 HGS
Mean 28.9
Standard deviation 4.1
Values 30 24 32
[68]
SNU475 HGS
Mean 43.1
Standard deviation 3.7
Values 40 46
[69]
THLE HGS
Mean 45.7
Standard deviation 2.6
Values 44 48
[70]
liver HGS
Mean 13.8
Standard deviation 3.3
Values 17 9.3 16 14
[71]
ref_hepatocyte SHC1
Mean 16.6
Standard deviation 7.2
Values 5.8 17 19 26 16
[72]
HepG2 SHC1
Mean 82
Standard deviation 0.099
Values 82 82
[73]
HepG2.C3A SHC1
Mean 84.9
Standard deviation 11
Values 77 93
[74]
HuH.7 SHC1
Mean 85.9
Standard deviation 2.4
Values 89 84 85
[75]
SNU475 SHC1
Mean 191
Standard deviation 36
Values 2.2e+02 1.7e+02
[76]
THLE SHC1
Mean 150
Standard deviation 11
Values 1.4e+02 1.6e+02
[77]
liver SHC1
Mean 40.4
Standard deviation 11
Values 37 32 56 37
[78]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[79]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[80]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[81]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[82]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[83]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[84]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[85]
ref_hepatocyte SH3GL1
Mean 12.4
Standard deviation 7.5
Values 7.4 8.5 25 13 8.1
[86]
HepG2 SH3GL1
Mean 57.7
Standard deviation 6.8
Values 63 53
[87]
HepG2.C3A SH3GL1
Mean 67.2
Standard deviation 9.8
Values 74 60
[88]
HuH.7 SH3GL1
Mean 36.1
Standard deviation 5.8
Values 39 29 40
[89]
SNU475 SH3GL1
Mean 33.1
Standard deviation 3.1
Values 35 31
[90]
THLE SH3GL1
Mean 46.9
Standard deviation 4
Values 44 50
[91]
liver SH3GL1
Mean 13
Standard deviation 6.5
Values 17 6.7 20 8.4
[92]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[93]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[94]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[95]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[96]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[97]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[98]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[99]
ref_hepatocyte CSK
Mean 10.6
Standard deviation 1.8
Values 11 8.9 13 9 11
[100]
HepG2 CSK
Mean 30.4
Standard deviation 3.7
Values 33 28
[101]
HepG2.C3A CSK
Mean 19.1
Standard deviation 3
Values 21 17
[102]
HuH.7 CSK
Mean 23.7
Standard deviation 5.3
Values 27 18 26
[103]
SNU475 CSK
Mean 19.3
Standard deviation 0.29
Values 19 20
[104]
THLE CSK
Mean 16.3
Standard deviation 1.9
Values 15 18
[105]
liver CSK
Mean 8.27
Standard deviation 2.7
Values 7.6 6.5 6.7 12
[106]
ref_hepatocyte PTPN12
Mean 9.2
Standard deviation 4.5
Values 11 14 12 5.3 3.4
[107]
HepG2 PTPN12
Mean 35
Standard deviation 1.2
Values 34 36
[108]
HepG2.C3A PTPN12
Mean 40.5
Standard deviation 2.5
Values 42 39
[109]
HuH.7 PTPN12
Mean 18.9
Standard deviation 1.1
Values 19 18 20
[110]
SNU475 PTPN12
Mean 57
Standard deviation 14
Values 47 67
[111]
THLE PTPN12
Mean 33.7
Standard deviation 3.5
Values 36 31
[112]
liver PTPN12
Mean 9.55
Standard deviation 3.7
Values 15 9.1 6.7 7.5
[113]
ref_hepatocyte PXN
Mean 9.17
Standard deviation 8.7
Values 3.1 8.2 24 4 6.1
[114]
HepG2 PXN
Mean 40.5
Standard deviation 4
Values 43 38
[115]
HepG2.C3A PXN
Mean 29.7
Standard deviation 0.97
Values 30 29
[116]
HuH.7 PXN
Mean 29.2
Standard deviation 3.3
Values 33 27 27
[117]
SNU475 PXN
Mean 73
Standard deviation 6.8
Values 78 68
[118]
THLE PXN
Mean 79.6
Standard deviation 9.5
Values 73 86
[119]
liver PXN
Mean 10.2
Standard deviation 5.9
Values 16 3.9 14 6.6
[120]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[121]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[122]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[123]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[124]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[125]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[126]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[127]
ref_hepatocyte ADAM10
Mean 8.78
Standard deviation 8.3
Values 21 13 2.8 3.4 3.4
[128]
HepG2 ADAM10
Mean 38.3
Standard deviation 10
Values 31 46
[129]
HepG2.C3A ADAM10
Mean 47.7
Standard deviation 4.9
Values 44 51
[130]
HuH.7 ADAM10
Mean 46.6
Standard deviation 9
Values 51 53 36
[131]
SNU475 ADAM10
Mean 39.1
Standard deviation 5.2
Values 43 35
[132]
THLE ADAM10
Mean 58.2
Standard deviation 3.8
Values 56 61
[133]
liver ADAM10
Mean 21.7
Standard deviation 10
Values 13 34 14 26
[134]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.1 7.4 4.2 8.1 14
[135]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 9.8 14
[136]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 9.6 13
[137]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 23 32 15
[138]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 80 35
[139]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[140]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 64 1e+02 32 1.4e+02
[141]
ref_hepatocyte PTPRK
Mean 6.9
Standard deviation 4
Values 14 5.7 5.6 4.1 5.2
[142]
HepG2 PTPRK
Mean 34.7
Standard deviation 11
Values 27 43
[143]
HepG2.C3A PTPRK
Mean 60.3
Standard deviation 12
Values 69 52
[144]
HuH.7 PTPRK
Mean 41.6
Standard deviation 9.2
Values 40 51 33
[145]
SNU475 PTPRK
Mean 19.2
Standard deviation 0.061
Values 19 19
[146]
THLE PTPRK
Mean 17.7
Standard deviation 4.8
Values 14 21
[147]
liver PTPRK
Mean 42.8
Standard deviation 13
Values 38 44 29 60
[148]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 27 1.9 2.2 1.3 1.5
[149]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 9.4 19
[150]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 39 33
[151]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 22 37 15
[152]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 25 20
[153]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[154]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 13 18 9.3 16
[155]
ref_hepatocyte PTPN3
Mean 6.09
Standard deviation 3.4
Values 2 3.5 6.4 10 8.5
[156]
HepG2 PTPN3
Mean 17.8
Standard deviation 1.5
Values 19 17
[157]
HepG2.C3A PTPN3
Mean 19.1
Standard deviation 3.7
Values 22 17
[158]
HuH.7 PTPN3
Mean 21.6
Standard deviation 1.3
Values 23 22 20
[159]
SNU475 PTPN3
Mean 9.15
Standard deviation 0.66
Values 9.6 8.7
[160]
THLE PTPN3
Mean 19.4
Standard deviation 0.74
Values 20 19
[161]
liver PTPN3
Mean 51.2
Standard deviation 8.7
Values 56 60 41 47
[162]
ref_hepatocyte LRIG1
Mean 5.62
Standard deviation 3.3
Values 1.3 5 4.1 8.3 9.5
[163]
HepG2 LRIG1
Mean 5.32
Standard deviation 1.1
Values 6.1 4.5
[164]
HepG2.C3A LRIG1
Mean 12.2
Standard deviation 2.2
Values 14 11
[165]
HuH.7 LRIG1
Mean 20.8
Standard deviation 1.2
Values 22 20 21
[166]
SNU475 LRIG1
Mean 1.37
Standard deviation 0.75
Values 0.84 1.9
[167]
THLE LRIG1
Mean 5.73
Standard deviation 0.44
Values 5.4 6
[168]
liver LRIG1
Mean 22.5
Standard deviation 14
Values 14 23 11 42
[169]
ref_hepatocyte EGFR
Mean 5.53
Standard deviation 4.2
Values 0.94 8.5 11 3.5 3.5
[170]
HepG2 EGFR
Mean 7.53
Standard deviation 0.89
Values 6.9 8.2
[171]
HepG2.C3A EGFR
Mean 5.18
Standard deviation 0.67
Values 5.7 4.7
[172]
HuH.7 EGFR
Mean 36.6
Standard deviation 25
Values 32 63 15
[173]
SNU475 EGFR
Mean 13.7
Standard deviation 0.74
Values 13 14
[174]
THLE EGFR
Mean 23.6
Standard deviation 4.4
Values 20 27
[175]
liver EGFR
Mean 49.4
Standard deviation 14
Values 39 69 47 42
[176]
ref_hepatocyte AREG
Mean 5.24
Standard deviation 9.3
Values 1.7 22 1.7 0.57 0.4
[177]
HepG2 AREG
Mean 1.59
Standard deviation 1.3
Values 2.5 0.67
[178]
HepG2.C3A AREG
Mean 0.15
Standard deviation 0.061
Values 0.11 0.19
[179]
HuH.7 AREG
Mean 0.0425
Standard deviation 0.021
Values 0.057 0.051 0.019
[180]
SNU475 AREG
Mean 0.0116
Standard deviation 0.016
Values 0.023 0
[181]
THLE AREG
Mean 16.4
Standard deviation 1.7
Values 15 18
[182]
liver AREG
Mean 0.00588
Standard deviation 0.012
Values 0.024 0 0 0
[183]
ref_hepatocyte ADAM17
Mean 5.04
Standard deviation 4.3
Values 10 8.5 4.3 1 1.1
[184]
HepG2 ADAM17
Mean 17.8
Standard deviation 0.96
Values 18 17
[185]
HepG2.C3A ADAM17
Mean 14.6
Standard deviation 0.94
Values 14 15
[186]
HuH.7 ADAM17
Mean 11.7
Standard deviation 1.5
Values 13 12 10
[187]
SNU475 ADAM17
Mean 31
Standard deviation 2.8
Values 33 29
[188]
THLE ADAM17
Mean 19
Standard deviation 2.3
Values 17 21
[189]
liver ADAM17
Mean 7.57
Standard deviation 0.72
Values 7.2 8.6 7 7.4
[190]
ref_hepatocyte EPS15
Mean 4.89
Standard deviation 1.8
Values 5.6 6.8 2.8 3.1 6.2
[191]
HepG2 EPS15
Mean 11.9
Standard deviation 1.7
Values 11 13
[192]
HepG2.C3A EPS15
Mean 19.5
Standard deviation 2.6
Values 21 18
[193]
HuH.7 EPS15
Mean 22.8
Standard deviation 3.3
Values 24 25 19
[194]
SNU475 EPS15
Mean 27.1
Standard deviation 6.2
Values 31 23
[195]
THLE EPS15
Mean 21.8
Standard deviation 0.2
Values 22 22
[196]
liver EPS15
Mean 32.9
Standard deviation 7.3
Values 27 42 27 36
[197]
ref_hepatocyte STAM
Mean 4.67
Standard deviation 4.3
Values 3.4 4.5 12 1.7 1.7
[198]
HepG2 STAM
Mean 21.4
Standard deviation 0.48
Values 22 21
[199]
HepG2.C3A STAM
Mean 26
Standard deviation 1.5
Values 25 27
[200]
HuH.7 STAM
Mean 12.8
Standard deviation 1.6
Values 15 11 13
[201]
SNU475 STAM
Mean 27.6
Standard deviation 1.8
Values 26 29
[202]
THLE STAM
Mean 19.2
Standard deviation 2.2
Values 18 21
[203]
liver STAM
Mean 5.6
Standard deviation 0.77
Values 5.9 5.8 6.3 4.5
[204]
ref_hepatocyte STAM2
Mean 3.7
Standard deviation 1.9
Values 6 5.1 3.6 1.5 2.3
[205]
HepG2 STAM2
Mean 9.81
Standard deviation 3.1
Values 7.6 12
[206]
HepG2.C3A STAM2
Mean 15
Standard deviation 2.6
Values 13 17
[207]
HuH.7 STAM2
Mean 7.81
Standard deviation 2.2
Values 7.1 10 6.1
[208]
SNU475 STAM2
Mean 20
Standard deviation 2.9
Values 22 18
[209]
THLE STAM2
Mean 13.6
Standard deviation 0.034
Values 14 14
[210]
liver STAM2
Mean 12
Standard deviation 2.6
Values 10 16 10 12
[211]
ref_hepatocyte SH3KBP1
Mean 3.69
Standard deviation 0.65
Values 3.7 4 4.6 3 3.1
[212]
HepG2 SH3KBP1
Mean 24.6
Standard deviation 3.6
Values 27 22
[213]
HepG2.C3A SH3KBP1
Mean 20
Standard deviation 1.3
Values 21 19
[214]
HuH.7 SH3KBP1
Mean 31.8
Standard deviation 7.3
Values 39 24 33
[215]
SNU475 SH3KBP1
Mean 23.4
Standard deviation 3.2
Values 21 26
[216]
THLE SH3KBP1
Mean 36.7
Standard deviation 7.1
Values 32 42
[217]
liver SH3KBP1
Mean 7.31
Standard deviation 4.4
Values 13 4.4 8.2 3.5
[218]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[219]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[220]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[221]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[222]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[223]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[224]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[225]
ref_hepatocyte PLCG1
Mean 3.54
Standard deviation 4.5
Values 11 2.4 1.7 0.91 1.2
[226]
HepG2 PLCG1
Mean 87.8
Standard deviation 4.3
Values 91 85
[227]
HepG2.C3A PLCG1
Mean 60.1
Standard deviation 10
Values 67 53
[228]
HuH.7 PLCG1
Mean 36.2
Standard deviation 5.9
Values 40 30 39
[229]
SNU475 PLCG1
Mean 45.9
Standard deviation 1.9
Values 47 45
[230]
THLE PLCG1
Mean 36.2
Standard deviation 0.92
Values 36 37
[231]
liver PLCG1
Mean 6.36
Standard deviation 4.9
Values 2.3 8.9 2.2 12
[232]
ref_hepatocyte EPS15L1
Mean 3.32
Standard deviation 2.4
Values 2.5 3 7.6 2.1 1.4
[233]
HepG2 EPS15L1
Mean 14
Standard deviation 0.62
Values 14 14
[234]
HepG2.C3A EPS15L1
Mean 11.2
Standard deviation 2.2
Values 13 9.7
[235]
HuH.7 EPS15L1
Mean 18.6
Standard deviation 0.34
Values 19 19 18
[236]
SNU475 EPS15L1
Mean 8.2
Standard deviation 0.13
Values 8.1 8.3
[237]
THLE EPS15L1
Mean 15.2
Standard deviation 2.3
Values 14 17
[238]
liver EPS15L1
Mean 5.82
Standard deviation 3.2
Values 8.4 3.1 8.8 3
[239]
ref_hepatocyte SPRY2
Mean 3.21
Standard deviation 2
Values 0.39 2.4 4.2 5.7 3.3
[240]
HepG2 SPRY2
Mean 4.68
Standard deviation 0.29
Values 4.9 4.5
[241]
HepG2.C3A SPRY2
Mean 4.63
Standard deviation 0.85
Values 5.2 4
[242]
HuH.7 SPRY2
Mean 23.8
Standard deviation 10
Values 27 12 32
[243]
SNU475 SPRY2
Mean 1.22
Standard deviation 0.58
Values 0.81 1.6
[244]
THLE SPRY2
Mean 5.56
Standard deviation 0.25
Values 5.4 5.7
[245]
liver SPRY2
Mean 5.14
Standard deviation 2.3
Values 4.7 5.4 2.4 8
[246]
ref_hepatocyte ARHGEF7
Mean 2.72
Standard deviation 0.57
Values 2 2.5 3.3 3.2 2.6
[247]
HepG2 ARHGEF7
Mean 18.5
Standard deviation 3.4
Values 16 21
[248]
HepG2.C3A ARHGEF7
Mean 16.4
Standard deviation 1.2
Values 17 16
[249]
HuH.7 ARHGEF7
Mean 14.2
Standard deviation 1.4
Values 14 13 15
[250]
SNU475 ARHGEF7
Mean 17.6
Standard deviation 3.5
Values 20 15
[251]
THLE ARHGEF7
Mean 16.6
Standard deviation 2.5
Values 15 18
[252]
liver ARHGEF7
Mean 19.7
Standard deviation 3.9
Values 24 19 15 21
[253]
ref_hepatocyte TGFA
Mean 2
Standard deviation 1.3
Values 3.8 2.7 2.1 0.72 0.76
[254]
HepG2 TGFA
Mean 15.3
Standard deviation 2.1
Values 17 14
[255]
HepG2.C3A TGFA
Mean 28.4
Standard deviation 4.2
Values 25 31
[256]
HuH.7 TGFA
Mean 0.0129
Standard deviation 0.0035
Values 0.016 0.013 0.0094
[257]
SNU475 TGFA
Mean 1.88
Standard deviation 0.53
Values 1.5 2.3
[258]
THLE TGFA
Mean 0.903
Standard deviation 0.47
Values 1.2 0.57
[259]
liver TGFA
Mean 2.16
Standard deviation 0.15
Values 2.1 2.3 2.2 2
[260]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 2.6 2.3 1.2 0.94
[261]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 2.1 4.3
[262]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 8 9.6
[263]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 10 12 7
[264]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 8.1 6.8
[265]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[266]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 6.1 15 6 13
[267]
ref_hepatocyte HBEGF
Mean 1.81
Standard deviation 1.5
Values 1 3.1 3.8 0.78 0.34
[268]
HepG2 HBEGF
Mean 2.02
Standard deviation 0.16
Values 2.1 1.9
[269]
HepG2.C3A HBEGF
Mean 1.02
Standard deviation 0.3
Values 1.2 0.82
[270]
HuH.7 HBEGF
Mean 0.469
Standard deviation 0.044
Values 0.52 0.43 0.46
[271]
SNU475 HBEGF
Mean 4.11
Standard deviation 0.34
Values 3.9 4.4
[272]
THLE HBEGF
Mean 3.71
Standard deviation 0.17
Values 3.8 3.6
[273]
liver HBEGF
Mean 0.478
Standard deviation 0.29
Values 0.89 0.27 0.28 0.46
[274]
ref_hepatocyte BTC
Mean 0.915
Standard deviation 1.9
Values 0 4.4 0.079 0 0.12
[275]
HepG2 BTC
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[276]
HepG2.C3A BTC
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[277]
HuH.7 BTC
Mean 0.087
Standard deviation 0.09
Values 0.066 0.19 0.0094
[278]
SNU475 BTC
Mean 0.229
Standard deviation 0.03
Values 0.25 0.21
[279]
THLE BTC
Mean 0.251
Standard deviation 0.13
Values 0.34 0.16
[280]
liver BTC
Mean 0.172
Standard deviation 0.058
Values 0.21 0.23 0.1 0.15
[281]
ref_hepatocyte SPRY1
Mean 0.868
Standard deviation 0.85
Values 2.4 0.27 0.51 0.41 0.79
[282]
HepG2 SPRY1
Mean 9.07
Standard deviation 0.37
Values 9.3 8.8
[283]
HepG2.C3A SPRY1
Mean 14.6
Standard deviation 0.14
Values 15 15
[284]
HuH.7 SPRY1
Mean 11.3
Standard deviation 4
Values 13 6.7 14
[285]
SNU475 SPRY1
Mean 2.02
Standard deviation 1.1
Values 1.3 2.8
[286]
THLE SPRY1
Mean 7.46
Standard deviation 1.7
Values 8.6 6.3
[287]
liver SPRY1
Mean 5.16
Standard deviation 2.8
Values 9.2 3.3 5 3.2
[288]
ref_hepatocyte GAB1
Mean 0.787
Standard deviation 0.67
Values 2 0.61 0.33 0.38 0.66
[289]
HepG2 GAB1
Mean 4.28
Standard deviation 2.2
Values 2.8 5.8
[290]
HepG2.C3A GAB1
Mean 8.12
Standard deviation 2.3
Values 6.5 9.8
[291]
HuH.7 GAB1
Mean 8.48
Standard deviation 1.4
Values 10 8.1 7.3
[292]
SNU475 GAB1
Mean 5.52
Standard deviation 1.6
Values 6.6 4.4
[293]
THLE GAB1
Mean 5.62
Standard deviation 0.39
Values 5.9 5.3
[294]
liver GAB1
Mean 8.2
Standard deviation 2.5
Values 7.1 10 5.3 10
[295]
ref_hepatocyte CBL
Mean 0.522
Standard deviation 0.26
Values 0.83 0.62 0.65 0.18 0.33
[296]
HepG2 CBL
Mean 25.2
Standard deviation 0.64
Values 26 25
[297]
HepG2.C3A CBL
Mean 10.8
Standard deviation 0.61
Values 11 10
[298]
HuH.7 CBL
Mean 12.1
Standard deviation 3
Values 15 11 9.5
[299]
SNU475 CBL
Mean 33.7
Standard deviation 5.1
Values 30 37
[300]
THLE CBL
Mean 26.4
Standard deviation 3.4
Values 24 29
[301]
liver CBL
Mean 10
Standard deviation 4.2
Values 5.8 14 7.1 14
[302]
ref_hepatocyte PAG1
Mean 0.46
Standard deviation 0.27
Values 0.11 0.83 0.58 0.44 0.33
[303]
HepG2 PAG1
Mean 0.592
Standard deviation 0.44
Values 0.91 0.28
[304]
HepG2.C3A PAG1
Mean 0.295
Standard deviation 0.023
Values 0.31 0.28
[305]
HuH.7 PAG1
Mean 26.9
Standard deviation 22
Values 16 53 12
[306]
SNU475 PAG1
Mean 6.18
Standard deviation 1.6
Values 5 7.3
[307]
THLE PAG1
Mean 15.2
Standard deviation 0.93
Values 16 15
[308]
liver PAG1
Mean 17.8
Standard deviation 8.2
Values 10 22 12 27
[309]
ref_hepatocyte EREG
Mean 0.24
Standard deviation 0.13
Values 0.3 0.18 0.15 0.13 0.45
[310]
HepG2 EREG
Mean 1.79
Standard deviation 1.2
Values 2.6 0.95
[311]
HepG2.C3A EREG
Mean 1.51
Standard deviation 1
Values 0.81 2.2
[312]
HuH.7 EREG
Mean 0.068
Standard deviation 0.032
Values 0.033 0.096 0.075
[313]
SNU475 EREG
Mean 0.149
Standard deviation 0.12
Values 0.065 0.23
[314]
THLE EREG
Mean 6.34
Standard deviation 2.2
Values 7.9 4.8
[315]
liver EREG
Mean 0.123
Standard deviation 0.11
Values 0 0.13 0.26 0.11
[316]
ref_hepatocyte SH3GL2
Mean 0.0479
Standard deviation 0.06
Values 0 0.041 0 0.052 0.15
[317]
HepG2 SH3GL2
Mean 0.0222
Standard deviation 0.023
Values 0.0057 0.039
[318]
HepG2.C3A SH3GL2
Mean 0
Standard deviation 0
Values 0 0
[319]
HuH.7 SH3GL2
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[320]
SNU475 SH3GL2
Mean 0.178
Standard deviation 0.19
Values 0.046 0.31
[321]
THLE SH3GL2
Mean 0.0849
Standard deviation 0.022
Values 0.1 0.069
[322]
liver SH3GL2
Mean 0.0774
Standard deviation 0.058
Values 0.047 0.014 0.1 0.15
[323]
ref_hepatocyte ADAM12
Mean 0.0114
Standard deviation 0.025
Values 0 0 0 0 0.057
[324]
HepG2 ADAM12
Mean 0.0158
Standard deviation 0.01
Values 0.023 0.0086
[325]
HepG2.C3A ADAM12
Mean 0.0199
Standard deviation 0.013
Values 0.029 0.011
[326]
HuH.7 ADAM12
Mean 0.0103
Standard deviation 0.013
Values 0.025 0.0064 0
[327]
SNU475 ADAM12
Mean 27.8
Standard deviation 14
Values 38 18
[328]
THLE ADAM12
Mean 3.87
Standard deviation 1.2
Values 3 4.7
[329]
liver ADAM12
Mean 0.293
Standard deviation 0.22
Values 0.047 0.4 0.54 0.19
[330]
ref_hepatocyte EGF
Mean 0.00415
Standard deviation 0.0093
Values 0 0.021 0 0 0
[331]
HepG2 EGF
Mean 0.0358
Standard deviation 0.014
Values 0.046 0.026
[332]
HepG2.C3A EGF
Mean 0.11
Standard deviation 0.087
Values 0.049 0.17
[333]
HuH.7 EGF
Mean 1.29
Standard deviation 0.44
Values 0.97 1.8 1.1
[334]
SNU475 EGF
Mean 3.97
Standard deviation 0.5
Values 4.3 3.6
[335]
THLE EGF
Mean 0.743
Standard deviation 0.02
Values 0.76 0.73
[336]
liver EGF
Mean 0.0176
Standard deviation 0.027
Values 0 0.057 0 0.013
[337]
ref_hepatocyte EPGN
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[338]
HepG2 EPGN
Mean 0.0544
Standard deviation 0.028
Values 0.074 0.034
[339]
HepG2.C3A EPGN
Mean 0.0501
Standard deviation 0.025
Values 0.068 0.032
[340]
HuH.7 EPGN
Mean 0.127
Standard deviation 0.084
Values 0.082 0.22 0.075
[341]
SNU475 EPGN
Mean 0.503
Standard deviation 0.27
Values 0.31 0.69
[342]
THLE EPGN
Mean 4.76
Standard deviation 1.2
Values 5.6 3.9
[343]
liver EPGN
Mean 0.161
Standard deviation 0.11
Values 0.12 0.17 0.051 0.3
[344]
ref_hepatocyte SH3GL3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[345]
HepG2 SH3GL3
Mean 0
Standard deviation 0
Values 0 0
[346]
HepG2.C3A SH3GL3
Mean 0
Standard deviation 0
Values 0 0
[347]
HuH.7 SH3GL3
Mean 0
Standard deviation 0
Values 0 0 0
[348]
SNU475 SH3GL3
Mean 0.281
Standard deviation 0.0029
Values 0.28 0.28
[349]
THLE SH3GL3
Mean 0.451
Standard deviation 0.0062
Values 0.46 0.45
[350]
liver SH3GL3
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0