REACTOME_SIGNALING_BY_CSF3_G_CSF | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -0.68[2] | -0.84[3] | -0.92[4] | -1.38[5] | -0.92[6] | -0.76[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -0.24[16] | -0.09[17] | -0.56[18] | -0.53[19] | -0.54[20] | -0.31[21] |
4 | UBE2D3 | Ubiquitin-conjugating enzyme E2 D3 | [22] | 0.69[23] | 1.05[24] | 1.06[25] | 0.66[26] | 1.13[27] | 0.97[28] |
5 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [29] | 2.20[30] | 2.14[31] | 2.95[32] | 0.87[33] | 1.68[34] | 0.46[35] |
6 | STAT3 | Signal transducer and activator of transcription 3 | [36] | 2.07[37] | 0.61[38] | 1.12[39] | 1.64[40] | 0.92[41] | 3.52[42] |
7 | PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 | [43] | 1.96[44] | 2.43[45] | 2.16[46] | 2.29[47] | 2.92[48] | 2.37[49] |
8 | GRB2 | Growth factor receptor-bound protein 2 | [50] | 2.71[51] | 2.59[52] | 2.48[53] | 1.96[54] | 1.87[55] | 1.41[56] |
9 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | [57] | 1.44[58] | 0.56[59] | 1.44[60] | 3.93[61] | 1.66[62] | 2.06[63] |
10 | RNF7 | RING-box protein 2 | [64] | 1.33[65] | 1.59[66] | 0.39[67] | 0.59[68] | 0.65[69] | 0.38[70] |
11 | SHC1 | SHC-transforming protein 1 | [71] | 2.68[72] | 2.94[73] | 2.78[74] | 4.05[75] | 3.54[76] | 1.89[77] |
12 | JAK1 | Tyrosine-protein kinase JAK1 | [78] | 2.03[79] | 1.55[80] | 1.51[81] | 2.03[82] | 2.67[83] | 2.64[84] |
13 | SOCS3 | Suppressor of cytokine signaling 3 | [85] | -2.62[86] | -3.00[87] | -1.51[88] | 0.60[89] | -0.47[90] | 1.25[91] |
14 | UBE2D2 | Ubiquitin-conjugating enzyme E2 D2 | [92] | 2.52[93] | 2.60[94] | 1.65[95] | 2.20[96] | 2.39[97] | 1.08[98] |
15 | KRAS | GTPase KRas | [99] | 1.00[100] | 1.02[101] | 2.39[102] | 2.20[103] | 1.86[104] | 1.79[105] |
16 | LYN | Tyrosine-protein kinase Lyn | [106] | 0.66[107] | 0.51[108] | 0.82[109] | 2.46[110] | 1.21[111] | 1.13[112] |
17 | TYK2 | Non-receptor tyrosine-protein kinase TYK2 | [113] | 2.66[114] | 3.05[115] | 2.95[116] | 2.15[117] | 3.07[118] | 3.10[119] |
18 | STAT5B | Signal transducer and activator of transcription 5B | [120] | 2.88[121] | 2.54[122] | 3.01[123] | 2.95[124] | 2.09[125] | 2.74[126] |
19 | CUL5 | Cullin-5 | [127] | 2.09[128] | 3.62[129] | 2.87[130] | 3.92[131] | 3.07[132] | 3.44[133] |
20 | UBE2D1 | Ubiquitin-conjugating enzyme E2 D1 | [134] | 2.31[135] | 3.22[136] | 3.33[137] | 2.92[138] | 2.68[139] | 1.61[140] |
21 | STAT5A | Signal transducer and activator of transcription 5A | [141] | -0.43[142] | 0.78[143] | -0.38[144] | 0.56[145] | 1.31[146] | 1.35[147] |
22 | SOCS1 | Suppressor of cytokine signaling 1 | [148] | 0.07[149] | 0.97[150] | 1.01[151] | -0.39[152] | -1.78[153] | -0.35[154] |
23 | CSF3 | Granulocyte colony-stimulating factor | [155] | -0.65[156] | -4.23[157] | -4.86[158] | -5.54[159] | 5.85[160] | -6.31[161] |
24 | GAB2 | GRB2-associated-binding protein 2 | [162] | 3.08[163] | 2.91[164] | 2.93[165] | 2.32[166] | 2.41[167] | 1.66[168] |
25 | HCK | Tyrosine-protein kinase HCK | [169] | -4.33[170] | -4.47[171] | [172] | -3.86[173] | -4.80[174] | 1.82[175] |
26 | JAK2 | Tyrosine-protein kinase JAK2 | [176] | 1.74[177] | 1.78[178] | 1.11[179] | 2.16[180] | 2.76[181] | 3.82[182] |
27 | CSF3R | Granulocyte colony-stimulating factor receptor | [183] | 2.47[184] | 4.84[185] | 4.29[186] | -4.36[187] | -6.30[188] | 3.57[189] |
28 | SYK | Tyrosine-protein kinase SYK | [190] | -6.65[191] | -0.74[192] | -3.98[193] | 1.50[194] | -2.02[195] | 4.47[196] |
29 | ELOC | Elongin-C | [197] | [198] | [199] | [200] | [201] | [202] | [203] |
30 | ELOB | Elongin-B | [204] | [205] | [206] | [207] | [208] | [209] | [210] |